University of Kentucky
Ashley W. Seifert is currently an Associate Professor in the Department of Biology at the University of Kentucky where his research group investigates animal regenerative biology and development. A major focus of his group is trying to understand the conditions that establish a regenerative microenvironment in response to injury. Specifically, his research seeks to identify the cell autonomous and non-autonomous mechanisms that support regeneration and how these mechanisms are curtailed in non-regenerating systems. Prof. Seifert's lab has pioneered the use of spiny mice to study complex tissue regeneration in mammals. His work has uncovered a key role for cellular metabolism regulating tissue healing across mammals and highlighted a role for specific macrophage populations to direct regenerative healing. In addition to studying tissue healing and regeneration in mammals, his lab also studies limb development and regeneration in salamanders.