The Labware Leachables SIG was started in 2012. The purpose of this SIG is to evaluate the prevalence of leachates in labware and evaluate what effect leachates may have on results. The SIG has been trying to determine if leachates are a significant problem and if so what can and should be done.
The 2020 Labware Leachables SIG will focus on what options do labware manufacturers have in addressing the issue of leachables in their products. To this point, the publications listed below discuss leachates in common labware.
Up for discussion at the 2020 SIG: What are manufacturers able to do to address Extractables and Leachables in their products? What does the cost/benefit analysis look like? Are end users concerned and are they willing to pay more for “Leachate Free” labware?
Peng J., et al. Chemical Identity and Mechanism of Action and Formation of a Cell Growth Inhibitory Compound from Polycarbonate Flasks. Anal. Chem. 2018, 990, 4603-4610 Hill EJ, Martin SJ, Weikart CM. Characterization of Extractable Species from Polypropylene Microplates. SLAS Technology 2018, Vol. 23(6) 560-565 Knight S., Identifying Inherent Contamination in Deep Well Microplates. Chromatography Today, May/June 2018