For decades, biological transistors have been touted as a potential gateway between digital and biological networks. Cardea’s graphene-based, biology-gated transistor platform harnesses hardware, software, and molecular infrastructure to detect and convert biological “signals” of interest into measurable digital information without the need for large expensive instrumentation, amplification or optics. In addition, we have developed methods for understanding device design from a system level. This is particularly important when the system must include active biological components. Last year, we demonstrated how the molecular machinery of a CRISPR complex could be used along with our transistors to create a “DNA Search Engine (CRISPR-ChipTM).” This year we show how that research, done in collaboration with the Aran Lab at KGI, has led to the Genome SensorTM. In addition, we will describe our Innovation Partnership Program for researchers and industry partners in life science (diagnostics, genomics, and drug discovery), agriculture, and food safety industry segments. Cardea’s infrastructure is helping the world Conduct Biology™ by opening the door to a universe of new applications and opportunities for portability and scalability. We're looking forward to collaborations with SLAS participants to continue to explore novel applications of Cardean transistors.