Drug Target Strategies
Protein Homeostasis: new drug discovery directions
Protein degradation is a very effective way to inhibit target activity and prevent its scaffolding function. At Cedilla, we are focusing on small molecules that directly or indirectly regulate the homeostasis of a protein of interest. This presentation will cover some of our strategic approaches to direct and indirect degradation and the contribution of biomolecular sciences (biophysics, biochemical, structural biology, molecular dynamics…) to this novel path in drug discovery.