Chief Technology Officer Pivot Park Screening Centre
Disclosure: Disclosure information not submitted.
Pivot Park Screening Centre (PPSC) is a small company that specializes in ultra-High Throughput Screening (uHTS) for drug discovery. We perform about 25 full deck screening campaigns a year on our own library of 300.000 compounds, the European Lead Factory library of 550.000 compounds and client libraries up to 1.000.000 compounds. In order to support this huge production we have implemented efficient processes on a fully automated screening system consisting of 3 robot pods integrated with a wide variety of instruments. Even in a highly automated environment like our uHTS lab, there is a continuous need for tools and little tricks to support our daily work. These include software tools to run active picking from the online store, re-use of (washed) verification plates, a simple tool for drying compound plates, implementation of a weighing station in the robot for checking dispensing performance, etc. Also, we have implemented cleaning stations for our heavily used certus dispensers. Finally, we make extensive use of a 3D-printer to create all sorts of tools in the lab and to save costs by printing parts of instruments that need repair. This presentation will provide insight in the daily operations in a uHTS lab.
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