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Development and Validation of Multiplexed Metabolic Assay Panel Using ECL Technology

Development of a Sensitive LC-MS/MS Method for the Quantification of a Stereopure Phosphorothioate Antisense Oligonucleotide in Human Plasma

Direct Measurement of the Intracellular Concentration of 8-Oxo-2'-Deoxyguanosine-5'-Triphosphate by LC-MS/MS

Effectively Utilizing Cutting-Edge Technologies in a Bioanalytical Lab to Improve Workflow Efficiencies

Efficient Optimization of an Affinity Capture Elution Procedure for Anti-Drug Antibody Assays by Applying a Design of Experiments Approach on the Gyrolab™

Evaluation of MRM Based Peptide Quantification, Using a Novel Triple Quadrupole Instrument with Optimized Ion Source E-Lens Technology and D Jet Ion Guide

High-resolution Characterization of Crystalline Protein Suspension Formulation by Solid-State NMR Spectroscopy: a Keytruda^TM Example

Improved LC-MRM Workflow for Cyclic Peptide Quantitation on Natriuretic Peptide Family

Optimization of an LC-MS/MS Generic Human IgG Assay Using Heat Stable Trypsin to Reduce Sample Analysis Time in Preclinical Samples

Parameters Affecting the Digestion Efficiency of a Monoclonal Antibody using a Generic LC-MS/MS

Screening of FDA-Approved Drug Library against Vancomycin Resistant Enterococci

Ultra-sensitive Quantitation of Intact Insulin Lispro Using a Novel Triple Quadrupole System

Assessment of Biotin Interference in Ligand Binding Assays

Challenges in Developing a Biomarker Assay for α-Synuclein Quantification

Continuous Monitoring of Biomarkers in Diabetic Rat Models under Stress Conditions

Dynamic Measurements of Dual Targets following the Administration of a Bi-specific Nanobody^® in Cynomolgus Monkey

Evaluating the Immune Modulatory Effects of Cancer Derived Membrane and Soluble Proteins and Mapping Their Immune Dominant Epitopes Using Bioinformatics

A Simple-Yet-Sensitive Use of Dried Plasma to Distinguish Estrogen-Negative Solid Tumors in Patient Samples

Retrospective Analysis of Singlicate vs Duplicate Testing of Clinical Synovial Fluid Samples for Alpha-defensin and Neutrophil Elastase Biomarkers of Periprosthetic Joint Infection

Validation and Clinical Diagnostic Accuracy of Immunoassays for the Ratiometric Determination of COMP and IL-8 in Synovial Fluid for the Differential Diagnosis of Idiopathic Osteoarthritis of the Knee

An Integrated, Automated Gating Pipeline to Analyze Large Scale and Multi-parameter Flow Cytometry Datasets from Clinical Trials

Challenges to Develop Immunoassays to Quantify Total and Phosphorylated BTK for Clinical Applications

Detection of Proteins at Low Attomolar and Sub-attomolar Concentrations Using Digital ELISA: Pushing the Detection Limits of Simoa Down by 100x

Development and Characterization of an Ultrasensitive Multiplex Biomarker Panel

Development of a Novel Ligand Binding Assay to Measure sBCMA in Human Serum

Compliant-Ready Intact Biotherapeutic Protein Quantitation Using Reconstructed Masses

FormylGlycinAmide Ribonucleotide (FGAR) Quantification following Glutamine Antagonist Anti-cancer Therapy Confirms Inhibition of Purine Synthesis

LC-MS/MS Quantitation of Endogenous Coagulation Factor XI and XII in Rabbit Plasma

An Adaptable and Robust Approach to Evaluating Pro-Inflammatory Biomarkers

Non-invasive Measurement of Lower Respiratory Cytokine Biomarkers with PExA and Ultrasensitive Immunoassays

Hybrid LBA-LC-MS/MS Method for Preclinical and Clinical Pharmacokinetic Assessment of Antibody Combination Targeting SARS-CoV-2 (AZD7442)

Lowering the LC-MS/MS Assay Quantitation Limit to 50 pg/mL for Ranibizumab in Human Plasma after Intravitreal Administration, by Using Sciex TripleQuad 7500 Mass Spectrometer

Reducing Soluble Target Interference in a Quantitative Ligand Binding Assay for a Bispecific Therapeutic Antibody

The Gyros Immunoassay Platform to Measure various Forms of a Therapeutic Antibody in Preclinical Studies

Improve Sensitivity for Quantification of Antisense Oligonucleotides in Plasma Using MicroLC-MRM Methodology

Development of LBA-LCMS Approaches for ADA Analysis in Pre-Clinical Studies

The Development of a Circulating Immune Complex (CIC) Assay

Modelling Unnatural or Modified Amino Acids for In Silico Immunogenicity Analysis

Visualization of Cut Point Data for Optimized Application in Anti-Drug Antibody Assays to Support Immunogenicity Testing

Evaluation of TOF MS Approaches for the Quantitation of Oligonucleotides

Identification and Relative Quantitation of Oligonucleotides and Impurities by a Data Dependent LC-MS/MS Method Using an Orbitrap Exploris 240 Mass Spectrometer

Bioanalysis of Permeation Enhancer Propyl Gallate and Metabolites for Oral Biotherapeutic Delivery: Overcoming Analytical Challenges

Evaluation of a Fully Automated Tip-on-Tip Bioanalytical Method for Total Nanoparticle Drug Quantitation in Rat Plasma by HILIC-UPLC-MS/MS

Investigation of Potential Chiral Inversion for SEP-363856 in Humans by Enantioselective LC-MS/MS Analysis of Human Plasma from Clinical Trials

Mathematical Modelling and Simulation for Predicting Lidocaine Systemic Exposure Following Topical Application on Human Subjects

Real-time Assessment of Aerosol Size Distributions from Vaping Products and Vitamin E Acetate Formulations

The Development of New High-Throughput Experimentation and Analytics Capabilities to Meet ICH-Q3D Requirements

HRMS/MS Based Quantification of Physiological Amines and Amino Acids by Chemical Isotope-Labeled Marfey's Reagent

Sample Preparation Options for a Panel of Endogenous Steroids in Serum Using Supported Liquid Extraction (SLE) or Solid Phase Extraction (SPE)

Sensitive and Comprehensive Lipid Mediator Profiling using Advanced Scheduled MRM with Polarity Switching and QTRAP Enhanced Product Ion Scanning

Simultaneous Determination of Apomorphine-Glucuronides and Norapomorphine-Glucuronides in Human Plasma by LC-MS/MS and Its Clinical Application

Targeted and Untargeted LC-HRMS-Based Metabolomics to Identify Novel Biomarkers of Antibacterial Resistance

Aspects of Matrix and Analyte Effects in Clinical Pharmacokinetic Sample Analyses Using LC-ESI/MS/MS – Two Case Examples

Contamination in Assays Which Are Designed to Aerosolize; Troubleshooting Albuterol

Evaluation of Streamlined SPE Processing of Pharmaceuticals Prior to LC-MS/MS Analysis

Mitigation of Significant Matrix Suppression, Adsorption, and Temperature Sensitivity toward the Accurate Quantification of a Small Molecule by LC/MS

Simultaneous Analysis of COVID-19 Drugs Candidates in Human Plasma by LC-MS/MS

Simultaneous Determination of Risperidone, Olanzapine, Aripiprazole, Amisulpride, Quetiapine, Haloperidol, Zuclopenthixol, and Fluphenazine (8-in-1) in Human Plasma by LC-MS/MS

The Passage of Drugs into Breast Milk: New Data for Untested Medications

Development and Validation of a High-Performance Liquid Chromatography Based Analytical Assay for Determination of Naloxone Hydrochloride in Skin Permeation Studies

Synthesis and Chromatography of the Sulfation Metabolite of A Natural Product- Ursolic Acid

Development of the Scientific Rationale for the Evaluation of Different Calibration Models (Regression and Ratio Based) Used for In Vitro BE Analysis

Targeting BRAF WT Metastatic Melanomas: Identifying ERBB4 Mutant Alleles as Biomarkers and Targets for Novel Combinatorial Treatment Strategies

4D Bioprinting Platform for Skin Regeneration in Diabetic Foot Ulcer Treatment

Dulaglutide 4.5 mg Administered as a Single Dose Pen Achieved Comparable Relative Bioavailability to Prefilled Syringe Administration in Healthy Subjects

Micropore Closure Time after Dermal Microneedle Application in Subjects of Diverse Ethnic/Racial Skin Types

Pharmacology, Immunogenicity, and Safety of PF-06881894, a Proposed Biosimilar to Pegfilgrastim, Versus US- and EU-Approved Pegfilgrastim Reference Products (Neulasta^®) in Healthy Volunteers

Defining the Role of the Neonatal Fc Receptor (FcRn) during the Traffic and Recycling of IgG in Down Syndrome (trisomy 21)

Co-culturing Cancer and Fibroblast Cells into Multicellular Spheroids to Mimic Solid Tumors

Formation of Multivalent Complexes in the Presence of More Than One Conventional Antibody to Complement Factor C5

Preliminary Investigation of Ketoprofen Release from Semisolid Formulations Using the Phoenix™ DB-6 Diffusion Tester

Comparison of Numerical and Mechanistic IVIVC: A Comprehensive Analysis on the Methodologies Using a Case Study of an Oral Extended-Release (ER) Drug Product

Application of Minimal Physiologically Based Pharmacokinetic Model for Insulin: A Population Analysis

Physiologically Based Pharmacokinetic Modeling of Oxybate: The Role of Counter-ions in Gastrointestinal Absorption

Monte-Carlo Simulation of Pharmacokinetics of Nexium DR Capsule (20mg)

Population Analysis of In Vivo Release Profiles of Modified Release Drug Products

Target-Mediated Disposition Pharmacokinetics (TMDD) Model of Recombinant Human Erythropoietin (rHuEpo) in Patients Undergoing Hematopoietic Transplantation

Characterization of the Nonlinear Pharmacokinetics and Time-Varying Clearance of Anifrolumab in Patients With Active Systemic Lupus Erythematosus

Population Pharmacodynamic Modeling of Intramuscular and Oral Dexamethasone and Betamethasone Effects on Six Biomarkers with Circadian Complexities in Indian Women

Quantitative Systems Toxicology (DILIsym) Modeling of the Acetaminophen (Paracetamol) Mode of Action (MOA) Pathway for Hepatotoxicity Supports that Acetaminophen Is Not a Carcinogenic Hazard in Humans

The Importance of Clinical Pharmacology in the Development of Biosimilars: A Retrospective Analysis of Products Approved by EMA and FDA

Effects of Riluzole Treatment on the Pharmacokinetics of Concomitant Medications in Patients with Acute Spinal Cord Injury: Oxycodone and Acetaminophen

Rivaroxaban Pharmacokinetics in Obese Patients: A Systematic Review

Bioequivalence of Elagolix with Estradiol/Norethindrone Acetate Fixed Dose Combination Product

Creation of an Inventory of Quality Markers Used to Evaluate Pharmacokinetic Literature: A Systematic Review

Phase Ia and Ib Double-Blind Randomized Clinical Study to Evaluate the Safety, Tolerability and Pharmacokinetics of a Novel Oral Amphotericin B Formulation (ICO-019) in Healthy Human Subjects

Strengthening the Quality of Clinical Pharmacokinetic Studies: Development and Validation of a Critical Appraisal Tool for Clinical Pharmacokinetic Research

Environmental Harmonization in Multi-Application Sunscreen Use: In Vitro Permeation Testing to Healthy Volunteers

Can Exenatide ER be Administered Every Four Weeks? PBPK Analysis Supporting Dosage Regimen Change

A Pregnancy Physiologically Based Pharmacokinetic (PBPK) Model for Antipsychotics

Comparison of PBPK Models for Evaluation of Clinical PK Exposure and Drug-Drug Interactions with the CYP3A4 Inhibitor Itraconazole

Guiding Predictive Performance of a Physiologically Based Pharmacokinetic (PBPK) Pregnancy Model for Labetalol Using Sensitivity and Parameter Contribution Analysis

Identifying Parameters to Improve the Pharmacokinetics and Tumor Delivery Efficiency of Nanomedicine

Investigation of Changes in Pimavanserin Pharmacokinetics (PK) in Patients Suffering from Child Pugh A (mild), Child Pugh B (moderate), and Child Pugh C(severe) Hepatic Impairment

Investigation of the Oral Absorption of Azithromycin in Adults and Paediatrics Based on PBPK Modeling

PBPK Model Based Virtual Bioequivalence Assessment of Different Elagolix Formulations to Support Regulatory Biowaiver

Pharmacokinetic Profile and Physiologically Based Pharmacokinetic Modeling of Matrine in Healthy Human Plasma and Saliva

Physiologically-Based Pharmacokinetic Model for Coproporphyrin I as an Endogenous Biomarker of OATP1B Transporters – Impact of SLCO1B1 Genotype, Ethnicity, and Sex on Its Inter-individual Variability

Physiologically-Based Pharmacokinetic Modeling of Chloroquine in Rat and Man

Predicting Local and Systemic Piroxicam Concentrations Following Topical Application using PBPK Modelling

Quantitative Prediction of Creatinine-Drug Interaction in Chronic Kidney Disease Population Using PBPK Modelling

Modeling the Pharmacokinetics of Soluble-to-Insoluble Phase Transitions

Population Pharmacokinetic Modeling of Intramuscular and Oral Dexamethasone and Betamethasone in Indian Women

Quantitative Systems Toxicology Modeling Using DILIsym Suggests That Drug-Induced Liver Injury Can Be Enhanced by Co-administered Drugs and Mitigated by Mitochondrial Biogenesis

openNCA - New Open-Source Non-Compartmental Analysis System and Pharmacokinetic Results Repository

Prediction of Human Brain Distribution of P-glycoprotein Substrate Drugs Using the Proteomics-Informed Relative-Expression Factor Approach and Verification Using PET Imaging

A Clinical Study to Assess the Bioequivalence of Lidocaine and Prilocaine Topical Drug Products Using Dermal Open Flow Microperfusion

Characterization of Human AME for Targeted Covalent Inhibitors (TCIs): Review of FDA Oncology Approvals

Relative Bioavailability of Ertugliflozin Tablets Containing the Amorphous Form vs Tablets Containing the Cocrystal

Development and Characterization of Human Immuno-Oncology Assays on a Multiplexed Electrochemiluminescence Platform

Multidimensional Chemical Library Screening for Novel Antibacterial Activities

Evaluation of Linked Protonation Effects on the Enthalpy of Phenobarbital Binding to Activated Carbon

3D Printed Wearable Biosensors: A Next-Generation Digital Healthcare Platform

Elucidating the Role of Phospholipid Remodeling Enzymes in Prostate Cancer Progression

Molecular Mechanisms of Cerebrovascular Inflammation in Alzheimer’s Disease

Repurposing an Irritable Bowel Syndrome Drug to Treat Late Stage Prostate Cancer

The BHMT-betaine Methylation Pathway Plays a Role in Oligodendrocyte Maturation under Oxidative Stress

Effect of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Immunodominant Peptide Antigens on Human Oral Mucosal, Nasal and Corneal Epithelial Cells.

Immune Tolerance-Adjusted Personalized Immunogenicity Prediction for Pompe Disease

Bioengineered In Vitro 3D Miniaturized Tuberculosis Mimetic Granulomas

Development and Qualification of a Novel In Vitro Assay of Oligodendrocyte Myelination and Demyelination using a Human Brain Spheroid Model

Development of a High-Throughput SARS-CoV-2 Strain-Typing Assay

Multi-Omics Approaches to Develop Genetic Signatures (mRNA, miRNA and miRNA-mRNA Pair) for the Aggressiveness of Prostate Cancers from Different Ethnicities

Role of Membrane-Associated Transporters in Modulating Fetal Drug Exposure: Relevance to Antiretroviral Drug Teratogenicity

The Involvement of Fatty Acid-Binding Proteins in Docosahexaenoic Acid Uptake in Microglia

In Silico Optimization of Amino-pyrazole Ureas as Anti-Leishmanial Agents

Synthesis and Evaluation of N^α,N^ε-diacetyl-L-lysine-inositol Conjugates as Cancer-Selective Probes for Metabolic Engineering of GPIs and GPI-Anchored Proteins

Multi-cytokine Inhibition and NKG2A+CD8 T-Cells in Humans with Immune and Hematologic Disorders: Computer-Aided Drug Discovery

C1 Analogues Have Improved Anti-Cancer Activity and Accumulation in TNBC Cell Line

Evaluating the PTP1B Inhibitory Potential of Dithiocarbamates

Sulfonamides Analogues of Homotaurine as Potential Treatment for Aβ plaques in Alzheimer’s Disease

Mastering Chemical Reactions on API Synthesis with Quantum Mechanics

Development of Immediate Release 3D Printed Tablet Produced via Fused Deposition Modeling of Phenytoin Drug

In Vivo Regulatory T Cell Induction by Lymphatic-Delivery of Long-Acting Butyrate Micelles

Ligand Mediated Differential Distribution of Decreased Nonspecific Adhesivity, Receptor-Targeted Nanoparticles in the Tumor Microenvironment

Monoglyceride-Based Thermally Sensitive Drug Delivery System

Novel Approaches for Identification of Preventative and Therapeutic Peptides against Zika Virus

Safety and In Vivo Gene Delivery Efficiency of COATSOME® SS-Lipids, a Lipid Nanoparticle Platform Composed of Biodegradable Ionizable Lipids

Selective Laser Sintering (SLS) Based 3D Printing of Magnetically Stimulated Pharmaceutical Dosage Forms

Self-Adjuvating Lipid Nanoparticle mRNA Vaccine Elicits T-Cell Responses and Protects Against Immune Challenge

Targeted Breast Cancer Therapy Using Nanoparticles Modified by Tumor-Homing Peptides

Use of Mycobacteria-Mimetic Metal-Organic Framework Particles as a Host-Directed Therapy Drug Delivery System for Tuberculosis

Integrity of the Blood Brain Barrier in a Rat Model of Gliadin-Induced Enteropathy

Experimental Measurements and Mathematical Modelling of Volatile Loss from Binary Solvent Systems

Exploring Multi-Compartment Plug–Flow Based Model Approach in Biopharmaceutics: Impact of Stomach Setting and the Estimation of the Fraction Absorbed of Orally Administered Basic Drugs

Molecular Dynamics Modeling Based Investigation of Cryoconcentration of Solutes during Freezing and Its Impact on Protein Stability

Utilizing Tiny-TIM to Assess the Effect of Proton Pump Inhibitors on the Absorptions of Oral Drug Candidates in Clinical Development

Fabrication of Novel 3D Printed Rapid-Setting Calcium Phosphate Bone Cement

Modulating Insulin Signaling/Uptake at the Blood-Brain Barrier Endothelium in Alzheimer’s Brain

Using Allosteric Peptides to Improve Selective Nanoparticle Uptake in CXCR4-Expressing Cells

RNA-Exo Codes: A Novel Biochemical Toolset for Real-Time Tracking Exosome Cargo Movement and Deposition

The Influence of External Lubrication on the Puncturing Properties of Hard Capsules for Dry Powder Inhalations

Development of a Synergistic Vector Based on Natural Polymers in Order to Reduce the Therapeutic Doses of Current Treatments and Their Adverse Effects in Chronic Inflammatory Bowel Diseases (IBD)

Effects of Polymer Properties on Poly(lactide-co-glycolide) Erosion and Degradation

Hydrogen-Sulfide Responsive Bicontinous Nanospheres for Treatment of Solid Tumors

Optimization of Efficacy and Safety of Novel Dexamethasone Prodrug Therapy through Dose Escalation in Treating Murine Lupus Nephritis

Pharmaceutical Excipient Compactions and Evaluation: Entrapped Air

Surface Chemistry and Generation Effect of PAMAM Dendrimers in HER2-Positive Breast Cancer Cells

Understanding HPC Polymer Chain Folding in Solutions

A Novel Rat Cervical Lymph Cannulation Method to Evaluate the Lymphatic Clearance of Therapeutics from the Brain

Age-Dependent Changes in the Plasma and Brain Disposition of Amyloid Beta Peptides and Insulin

Crystalline Sponges as a Sensitive and Tast Method for Metabolite Identification: Application to In Vitro Metabolites

Evaluating the IVIVC of Combining Tiny-TIM Outputs and Compartmental PK Model to Predict Oral Exposure for Different Formulations of Ibuprofen

Impact of Alzheimer’s Disease Amyloid-β Peptides on 18Fluorodeoxyglucose Transport into the Brain

Orbitrap Exploris 240 Mass Spectrometer with Novel Data Acquisition Features Ensures Confident Metabolite Identification and Structure Elucidation

Semi-mechanistic Pharmacokinetic Model to Predict the Impact of Age and Insulin Exposure on Alzheimer’s Disease Amyloid Beta Peptide Kinetics at the Blood-Brain Barrier

Synovial Permeability to Intraarticular Administered Drugs as Observed in an Inflammatory Explant Model

A Database of Pharmacogenomics Information Related to Minority Groups

Development of QSAR Models for Blood-Brain Barrier Permeability and Efflux Transporters

Fc-Fused Cocaine Hydrolase Blocks Cocaine-induced Alternation of Dopamine Transporter Distribution in Dopaminergic Neurons

Potential of Cebranopadol for Cocaine Abuse Treatment: Impact on Cocaine Abuse-related Animal Models and Its Safety Profile

Histone Post-Translational Modifications Induced by DNA Hypomethylating Agents

An mPGES-1 Inhibitor Alters the Growth of Abdominal Aortic Aneurysms in Mice

Combination of Photodynamic and Chemotherapeutic Agents in the Treatment of Psoriasis: Assessment of In Vitro Efficacy of Aminolevulinic Acid and Mycophenolic Acid

Comprehensive Analysis of Histone Posttranslational Modifications Induced by Curcumin Analog

Mechanistic Investigation of NAP1051, a Lipoxin A4 Biomimetic, in Treating Colorectal Cancer

The Cationic Peptide K16ApoE is Highly Effective against Staphylococcus epidermidis Biofilms

Programming Tumor-Clearing Macrophages with In Situ Gene Therapy

Characterization of the Immunopharmacology of Repository Corticotropin Injection (Acthar^® Gel) Compared with Synthetic ACTH_1-24 Depot and Methylprednisolone in Healthy Human Subjects

Anticancer Drug Transporters at the Blood-Brain Barrier: Impact on the Treatment of Glioblastoma

Dithiolethiones Exert Neuroprotection Against Iron Overload-Induced Ferroptosis in Human Glioblastoma Cells

A Deep Learning Framework for Integrating Heterogeneous Data in Predictive Toxicology

Using In Silico Prediction, In Vitro Validation and Next Generation Sequencing (NGS)-Based Characterization to Repurpose Novel Agents as Secondary Drugs against Taxane-Resistant Prostate Cancer

Combination of Gemcitabine and Cytidine Deaminase Inhibitor: A Breakthrough Cocktail for the Treatment of Pancreatic Ductal Adenocarcinoma

Drug Repositioning for Noonan and LEOPARD Syndromes by Integrating Transcriptomics with a Structure-Based Approach

Bioactivation of Diphenylamine NSAIDs into Quinone-Species Metabolites Varies Greatly with Minor Structural Modifications

Nonlinear Pharmacokinetic Modeling of a Weakly Basic, Highly Lipophilic Drug

The Relationship between Hydrophobicity and Fraction of Drug Metabolism

Regulation of bFGF-Induced Angiogenesis by Endothelial Small GTPase RhoA: A Potential Target for Anti-angiogenic Therapy

Adverse Outcome Pathway (AOP) Guided Modeling for Drug-Induced Liver Injury (DILI)

Subvisible Particles in Intravenous Infusion Bags

Pulmonary Delivery of Bevacizumab (Avastin™) in Sheep

Crafting Immunity: Novel Microparticulate Measles Vaccine for Needle-free Transdermal Immunization

CGMD and CFD Simulation of Continuous Manufacturing of Polymeric Micelles

Locally Trapping the CCL2 by Gene Delivery Nanoparticles Remodeled the Immunosuppressive Tumor Microenvironment and Inhibit Tumor Progression in Triple-Negative Breast Cancer

Design and Evaluation of Ketoprofen/PLGA Implants using Direct Powder Extrusion 3D Printing

Evaluation of Single Step Thermoplastic Extrusion as Potential Technique for Fabrication of 3D Printed Drug Loaded Polymeric Implants

Gentamicin Loaded 3D Printed Metal Implants for Post-Surgical Infections

Meloxicam Coated 3D Printed Stainless Steel Implants for Sustained Drug Delivery

High-Efficient Immune Cell Production of Extracellular Vesicles for Developing a Novel Nanodelivery Approach

Antibody Targeted Multifunctional Lipid-Polymer Nanoparticles Loaded with Temozolomide and ⁸⁹Zr Labeled for Theranostic Treatment of Glioblastoma

Assessment of 3D Printed Calcium Phosphate Cement (CPC) Scaffolds for Its Potential Applications in Tissue Engineering and Regenerative Medicine with Anti-cancer Properties

Combination of Human Insulin and Flurbiprofen Sodium into a Nasal Powder for a Multitarget Therapy in Alzheimer’s Disease

Development of Cefuroxime Loaded ZnO:MgO Nanoparticles and Evaluation of Their Internalization on T24 Cells

Development of Safe and Efficient Zwitterionic Polymer-Based Interferon-β1 DNA Polyplexes for Glioblastoma Therapy

Examining Subcutaneous Bioavailability of Therapeutic Monoclonal Antibodies and Fusion Proteins

Exosomes as Nano Delivery Systems for Treatment of Non-Small Cell Lung Cancer

Investigation of the Nanoparticle Distribution within the Peritoneal Cavity for the Treatment of Ovarian Cancer Metastasis

Large Immunomodulating Drugs Traffic Specifically through the Joint-Draining Lymphatics after Intra-Articular Compared to Subcutaneous Injection

Lipid Nanoparticles for M2-Type Tumor Associated Macrophages Specific Drug Delivery

Multi PEGylation Can Increase the Potency In Vivo Despite Loss of Potency In Vitro: A Case Study of PEGylated G-CSF

Nanomedicine-Based Gene Therapy for Treatment of Cancer Cachexia

PLGA Nanoparticle Formulation of the Novel mitoNEET Ligand NL-1 Improves Cerebral Outcomes after Stroke

Preparation and Characterization of PEGylated Nanostructured Lipid Carrier Systems for the Ocular Delivery of Antineoplastic Agent

Double-Coated Poly(butyl cyanoacrylate) Nanoparticles: A Potential Delivery System to Inhibit the Efflux Function of P-gp and BCRP Transporters in Acquired Multidrug-Resistant Cancer Cells

Formulation and Characterization of Inhalable Nano-lipid Carriers by Hot Melt Extrusion Techniques

Glycemic Effects of Bedtime Oral Insulin (ORMD-0801) in Uncontrolled Type 2 Diabetes Mellitus Patients

Preparation, Characterization and Stability Evaluation of Ligand Anchored Primaquine Loaded Nanostructured Lipid Carrier Systems for Liver Targeting

Reducing Subcutaneous Tissue Resistance with Recombinant Human Hyaluronidase PH20 Lowers Injection Force Required for Rapid, Large Volume Administration of Macromolecules

Developing a Double Layered Film Dosage Form for Drug and Vaccine Delivery Using Lidocaine as Model Drug

Localized Delivery of Glucose Oxidase and Catalase Enzymes in a Self-Assembling Peptide Hydrogel: Potential for Treatment of Diabetic Chronic Wounds

3D Printed Magnetically-Triggered Microspouter Encapsulating Drug-Loaded PLGA Nanoparticles

Development of PLGA-Based Implants Using Hot Melt Extrusion for Sustained Release of Drugs

Novel 3D Printing Technology for Formulation of Oral Dissolving Films (ODFs)

Targeting AT₁ Receptor in the Brain Using Dual Functionalized Liposomes for Treatment of Neurogenic Hypertension

Understanding the Impact of Intraperitoneal Insulin Catheter Size and Geometry on Fibrotic Response

Vitamin Lipid Nanoparticles Enable Adoptive Macrophage Transfer for the Treatment of Multidrug-Resistant Bacterial Sepsis

A Microparticle-Filled Drinking Straw for the Delivery of Metformin/Gliclazide Sustained Release Fixed Dose Combination

Antibody-Functionalised Electrosprayed Microparticles for T Cell Activation

A Broad AAV Formulation Platform for Bespoke Genomic Therapies

Brain-Targeted CRISPR/Cas9 Approach Knocking Down P-glycoprotein and Overcoming Pharmacoresistance at the Blood-Brain Barrier

Development and Validation of Brain Targeted Liposome-Based Gene Therapy for an Effective Treatment of Alzheimer’s Disease

Development of TRPV1 siRNA Lipid Nanoparticles for Neuropathic Pain Therapy

Extracellular Vesicles for the Delivery of Neurotrophin DNA to Brain Endothelial Cells

Improved Insulin Sensitivity in Obese-Diabetic Mice via Chitosan Nanomicelles Mediated Silencing of Pro-Inflammatory Adipocytokines

In Vitro and In Vivo Evaluation of Liposomes Mediated ApoE2 Gene Therapy for the Treatment of Alzheimer’s Disease

Stabilization and Release Characteristics of Recombinant DNA in a Polymer Based Film Matrix

Tinagl1 Gene Therapy for Tumor-Wide Remodeling of Triple Negative Breast Cancer

Entrapment of β-Cyclodextrin/Hispolon Inclusion Complex Inside Liposomes: Enhancement of Loading Efficiency and Release Properties

Gentle Drying for Thermosensitive Active Pharmaceutical Ingredients

The New Buzz in Adjuvant Research: Exploring Adjuvant Potential of Microparticulate DPD and Its Analogs

Excipient Combinations to Manage Protein Viscosity for Highly Concentrated Formulations

Expanding the Toolbox of Surfactants Available for Biologics Formulations with Kolliphor® HS 15 and Kolliphor® ELP

Extending Shelf Life of Therapeutic Proteins with Hydroxylpropyl ß-Cyclodextrins - Mechanistic Understanding of Bevacizumab Stabilization

Hydrophobe Variation in Surfactant Excipient Significantly Impacts Fundamental Performance and Biologic Stability in Liquid Formulation

In Situ Investigation of Freeze-Thaw Induced LDH Aggregation in Sodium Phosphate Buffer using Neutron Scattering

Mechanistic Investigation of Spray Drying Process and Excipients Effects on Sb-ABAB Cell Stability using In-Cell Fast Photochemical Oxidation of Proteins (IC-FPOP) and Homology Modeling

Physicochemical and Functional Characterization of Pea Protein and Rice Protein Isolates as Pharmaceutical Excipients

Quantifying Excipient Effects on the Helix Secondary Structure in Formulation of Biologic Compounds

Thinking Outside the Box: The Protective Role of Buffer Systems in Bacteriophage Formulation During Processing with Thin Film Freeze Drying

Effect of Lactoferrin and Lysozyme Containing Formulations on Skin Wound Healing

Formulation of PLGA/PEG-PLGA Nanoparticles for Prolonged Release of Granulocyte-Macrophage Colony-Stimulating Factor in the Breast Tumor Microenvironment

In Vivo Stability of Therapeutic Proteins

Immunotherapy Against Cancer Stem Cells Using Synthetic High-Density Lipoprotein Nanodiscs

The Effect of Molecular Weight of the Amino-Dextran on the In Vitro Uptake by Splenic Immune Cells

Applying Computational Prediction of Biorelevant Solubility in Dispersions of Self-Emulsifying Lipid-Based Formulations to Predict Dose Number

Development of a Systematic In Vitro Permeation (IVPT) Method for Dermatological OTC Products Exercising Regulatory Guidance

Development of a Level A IVIVC for an Immediate Release Formulation

Microwave Assisted Synthesis and Characterization of a 4-bromophenylboronic Acid Closo-nanoconjugate for HIV Virion Capture

Optimizing Nitrogen Mustard Administration to Obtain Reproducible Model Vesicant Skin Burns

Integrating Drug Product Quality Attributes in a Bottom-Up Physiologically Based Pharmacokinetic (PBPK) Model to Simulate In Vitro Skin Permeation of Acyclovir Commercial Formulations

Understanding In Vivo Dissolution of Solid Oral Ibuprofen Immediate-Release Drug Products Using Deconvolution Methodology

Understanding In Vivo Drug Dissolution of Indomethacin Immediate Release Drug Products to Guide Biopredictive In Vitro Dissolution Method Development

A Comparative Study on Fabrication Methods for Microparticle-Based Drug Delivery Systems

An Injectable Liquid Crystalline Semi-gel System for One-Month Delivery of Leuprolide

Development of Radiolabeled Surrogate Beads for Tracing Gastrointestinal Transit of Oral Multiparticulate Formulations

Drug Particle Characterization Inside Long-Acting Intrauterine Systems with 3D Imaging Analytics

Effect of PLGA Raw Material on In Vitro and In Vivo Performance of Microsphere Controlled Release of Leuprolide Acetate and Triamcinolone Acetonide

Extended Release (Regulatory T Cell Inducing) Microsphere Formulation for the Treatment of Periodontal Disease

In Situ Metronidazole Gel Delivery for the Treatment of Jawbone Infections

Integrated In Vitro-In Silico-In Vivo Approach for Developing Controlled Release Microspheres for Pre-Clinical Studies

Investigation of Gelation Time Controllable Long-Acting In Situ Forming Gel

Local Corticosteroid Delivery to the Paranasal Sinuses via a Thermoresponsive and Extended Release System

One Month Contraception with Controlled Release Etonogestrel from PLGA Microspheres Administered by a Dissolvable Microneedle Patch

Permeation and Absorption of Ethanol/Water Mixture through Ethylcellulose Film

Physiologically-Based Pharmacokinetic Model to Describe the Pharmacokinetics of Crushed Morphine Sulfate and Naltrexone Hydrochloride Extended-Release Capsules with Abuse Deterrent Properties

Superior Performance of Silicified Microcrystalline Cellulose in Development of Stable and Robust Multiple Unit Pellet System (MUPS) Tablets

Ultra-long-acting Oral Drug Delivery Using a Single-component Hydralese™ (PGSU) Gastroretentive Device

A Lipid-Based Nanocarrier Containing Dacarbazine and Resveratrol for Treatment of Cutaneous Melanoma

Application of Magnetic Field Induction to Enhance the Function of Magnetic Nanoparticles – In Vivo Rat Model for Glioblastoma Multiforme

Brain Distribution Kinetics of Intranasal Fluorescent-Labeled Nanoemulsion

Charge-Based Interactions Enhance Penetration of Positively Charged Peptide Surfaces through Tumor Extracellular Matrix

Co-delivery of Paclitaxel and Ritonavir Nanomicelles Targeted with Hyaluronic Acid for Treatment of Metastatic Breast Cancer

Combination of STING and TLR 7/8 Agonists as Vaccine Adjuvants for Cancer Immunotherapy

Delivery of Hydrogen Sulfide via Novel PEG Brush Polymers as a Means of Ameliorating Oxidative Stress

Design and Evaluation of Albumin-oleic Acid Conjugated Nanoparticles Containing Bulky and Poorly Water-Soluble Model Drug

Design, Development and Optimization of New 8-aminoquinoline Derivative Loaded Nanostructured Lipid Carriers Using Central Composite Design for Malaria Treatment

Development and Evaluation of Sterylamine-Lactobionic Acid Conjugate Attached New 8-aminoquinoline Derivative Loaded Nanostructured Lipid Carriers for Liver Targeting

Development and Evaluation of Transferrin Conjugated Amodiaquine Nanoparticles - Non-Small Cell Lung Cancer (NSCLC) Targeted Therapy

Development and In Vitro Characterization of Folate Conjugated PLGA Nanoparticles of Lutein

Efavirenz Delivery to Brain Using Solid Lipid Nanoparticles for Potential Management of Neuro-AIDS

Engineering Nanoparticles to Evade Phagocytic Clearance for Pulmonary Drug Delivery

Hyaluronic Acid Nanogel for Protein Delivery System

In Vitro Assessment of Stearyl Triphenyl Phosphonium Toxicity in Drug Resistant Tumor Cells

Investigation of Surface Charge Effects on Insulin-Loaded Thermoresponsive Biodegradable Nanogels Intended for the Treatment of Diabetic Retinopathy

Liposomal Delivery of Azido Compound for the Determination of Subcellular Drug Delivery in Gram-Negative Bacteria

Liposomes and Transferosomes for the Topical Delivery of Papain in the Treatment of Hypertrophic Scars

Local Delivery System of Antiemetic Drug for Cancer Patients

Lutein Encapsulated Biotinylated PLGA Nanoparticles for the Treatment of Age-Related Macular Degeneration

Novel Orlistat Low Density Lipoprotein (LDL) Nanoparticles: Evaluation of Concentration Dependant Ripening of Particles

nTRACK: Non-invasive Imaging Model with Gold Nanoparticles for Stem Cell Tracking on a Muscle Regeneration

Optimization of Cholesterol/Polycaprolactone-Based Perfluorooctyl Bromide Nanocapsules and Its Impact on X-ray CT Attenuation for Tumor Imaging

Overcoming Biological Barriers to Enhance Protein Nanoparticles Delivery to Brain by Red Blood Cell Hitchhiking

PD-1 siRNA-Encapsulated Solid Lipid Nanoparticles Down-Regulate PD-1 Expression by Macrophages and Inhibit Tumor Growth

PEGylated Single Walled Carbon Nanotubes in Alzheimer’s Disease Drug Delivery

Rational Engineering of Polymeric Nanocarriers for Enhancing Selective Delivery to Vascular Endothelium

Synthesis and In Vitro Evaluation of Novel Indocyanine Green Loaded Hyaluronic Acid Nanoparticles for Bioimaging of Pancreatic Cancer

Understanding the PK-PD Relationship Governing Nanoparticle Formulations of STING Agonists for Systemic Administration

Using Nanomedicine to Hijack Lipid Metabolism in Glioma Cells and Hypothalamic Neurons by Blocking Carnitine Palmitoyl-Transferase 1 (CPT1)

Assessing the Pharmacokinetics and Biodistribution of Amphotericin B following Oral Administration of Three Novel Oral Amphotericin B Formulations to Beagle Dogs

Bioavailability of Apalutamide Tablets Administered in Applesauce and Use of Yogurt, Orange Juice, and Green Tea as Alternate Food Vehicles

BioRAM-Based Decision-Making: A Blueprint for Success

Compositions for Hormone Free Woman-Controlled Contraception

Development and Category-1 In Vitro Evaluation of Extended Release Pellets Prepared by Hot Melt Extrusion Techniques: Role of Gelling Agents in the Mitigation of Intravenous Abuse

Effect of γ-cyclodextrin Hydrolysis on Dexamethasone Release from Aqueous Complex Solution Containing Porcine Pancreatic α-amylase

Effect of Recycling on Printability of Pharmaceutical Powder Blend in SLS 3D Printing

Evaluation of Carrying Capacity of Directly Compressible (DC) Excipients

Feasibility Studies for the Preparation of a Paclitaxel Hydrazide Derivative for Enhanced Solubility and Drug Delivery

Investigation of Impact of Hydrophilic Binders in Lipid-Based Sustained Release Formulations of Quetiapine Fumarate by Twin-Screw Melt Granulation

Leaf Extract of Crinum Latifolium Suppresses EGF-induced Proliferation of C4-II Cervical Cancer Cells

Successful Replacement of EUDRAGIT^® NE 30 D with EUDRAGIT^® NM 30 D in Delayed Release Coating Systems of EUDRAGIT^® L 30 D-55

Design and Development of an Ophthalmic Nanoemulsion Topical Formulation for Corneal Wound Healing

Development and Characterization of Hot-Melt Extruded Ocular Inserts of Moxifloxacin for Bacterial Keratitis

Novel, Fast-Equilibrating, Ophthalmic Vehicle for Enhanced Patient Comfort and Tolerability for Pilocarpine Delivery

Characterization of Human and Porcine Gingiva for Drug Absorption

Establishment of In Vitro Evaluation System on Intranasal Dissolution for Nasal Powder Formulations

Evaluating 1,4-Dioxane as Permeability Enhancer Using Lidocaine as Model Drug in a Film Drug Dosage Form for Buccal and Sublingual Administration

Hybrid CFD-PBPK Model for Prediction of Systemic PK Following Nasal Insufflation of Milled Oxycodone Hydrochloride Extended-Release Tablets

A Mechanistic Evaluation of How Metamorphosis of a Topical Dosage Form Impacts Permeation

A Mechanistic Evaluation of the Impact of Formulation Viscosity and Fractional Solubility on Drug Release and Permeation

A Systematic Process for the Synthesis of Nanospheres for Ungual Delivery of Terbinafine Hydrochloride

Assessing Topical Drug Clearance from the Skin Using Raman Spectroscopy

Assessing Topical Drug Penetration into the Skin Using Raman Spectroscopy

Comparative Evaluation of the Permeation of Metronidazole Using Static Diffusion Cells and Flow-through Diffusion Cells

Critical Quality Attributes of Topical Clobetasol Propionate Foams

Dacarbazine Polyphenol Polymeric Nanocarriers for Transdermal Delivery in the Treatment of Melanoma

Development of Lysozyme Loaded Microneedles for Dermal Applications

Effect of Formulation Parameters on Permeation of Ibuprofen from Semisolid Topical Formulations

Enhanced Drug Loading in In Situ Forming Gel for Oral Mucositis Pain Control

In Vitro Evaluation of Poloxamer 407 as a Potential Vehicle for Delivery of Diclofenac to Chronic Wound Sites

Interaction Studies of Tretinoin with Microspheres in Tretinoin Topical Gel

Microstructural Characterisation of Microsponge-Based Gel Products using Cryo SEM

Nanocrystals for Improved Topical Drug Delivery of Apremilast

Physicochemical Properties of Poloxamer Gels Used to Improve Microneedle-Assisted Transdermal Delivery of Naltrexone

Preparation, Characterization and IVRT Study of Tretinoin Loaded Microspheres in Topical Gel Product

Rheological Characterization of Topical Clobetasol Propionate Foams

Sensory Profiling of Metronidazole Topical Semisolid Products by Descriptive Sensory Analysis

Topical and Transdermal Delivery with Diseased Human Skin: Passive and Iontophoretic Delivery of Hydrocortisone into Psoriatic and Eczematous Skin

Transdermal Delivery of Breakthrough Therapeutics against Treatment-Resistant and Post-Partum Depression

Nose to Brain Drug Delivery of Aerosolized Nanoparticles

Application of Polyvinyl Chloride to Thermoresponsive Drug Carrier

Design Options for FDM 3D Printed Tablets: Tailoring Drug Dose and Drug Release Performance

Development and Evaluation of a Self Emulsifying Drug Delivery System of Etoricoxib

Formulation Development and Characterization of Rapid Acting Microneedles to Treat Biofilm Infections

Lipid-Based Formulation Development of Poorly Soluble Drug for Fast Access to Animal and Human PK Proof of Concept

Sulfobutylether-β-Cyclodextrin Microneedle Arrays for Hydrophobic Drug Delivery

Zero-Order Release of Hydrophilic Drugs at High Loadings Using Novel Biodegradable Elastomer Hydralese™ (PGSU)

Development of Sustained-Release Gastro Retentive Floating Tablets Using HME Coupled 3D Printing: A QbD Approach

Medication Swallowing Lubricants as a Vehicle for Oral Drug Delivery for Patients with Dysphagia

Novel On-Demand 3D Printed Devices Using Fill Density as an Effective Release-Controlling Tool

Evolution of a Software as Medical Device from Concept to Reality

Absorption Driven Drug Formulation through the Example of Telmisartan

Dissolution Kinetics of pH Sensitive Drugs in an Artificial Stomach and Duodenum Apparatus

Membrane-Drug Binding and Its Impact on In Vitro Release of Dexamethasone

Method Comparison for Bioequivalence Prediction through the Example of Aripiprazole

Predictive Performance Comparison of Computed Multivariate Calibration Models for In Situ UV Fiber Optics Tablet Dissolution Testing

Amorphous Drug-Polymer Salts with High Stability under Tropical Conditions and Fast Dissolution: The Case of Lumefantrine-PAA

Atorvastatin Calcium-Plasdone^TM S-630 Based Amorphous Solid Dispersions Produced by Hot Melt Extrusion Technique

Characterization of Grades of HPMCAS Spray Dried Dispersions of Itraconazole Based on Supersaturation Kinetics and Molecular Interactions Impacting Formulation Performance

Comparison between Phase Diagrams of Solid Dispersion System Using Different Analytical Techniques

Competition Between Dissolution and Matrix Crystallization of Bicalutamide-PVPVA Amorphous Solid Dispersions Containing Residual Crystallinity

Counterions Facilitate High Drug Loading in Amorphous Solid Dispersion

Development and Characterization of Drug-Drug-Polymer Ternary Amorphous Solid Dispersion

Disparities of Single Particle Growth Rates in Buried versus Exposed Ritonavir Crystals within Amorphous Solid Dispersions

Effect of Carrier Type and Drug Loading on the Physical Stability and Compaction Behavior of Amorphous Solid Dispersions Containing Indomethacin

Effect of Carrier Type and Tween® 80 Concentration on the Silymarin Release from the Solid Dispersion

Effect of Plasdone^TM Copovidones on the Stability of Atorvastatin Calcium Trihydrate Amorphous Solid Dispersions Prepared via Hot Melt Extrusion: Role of Plasticizers in Processability and Stability

Effect of Polymers on Crystallization in Glass-Forming Molecular Liquids: Equal Suppression of Nucleation and Growth and Master Curve for Prediction

Enhancement of Solubility and Permeability of Hydrochlorothiazide by Co-crystallization Using Hot-Melt Extrusion

Evaluation of Different Opadry Film Coating Systems on Tablets Containing Amorphous Solid Dispersion of Itraconazole

Flexible Formulation Assessments in FIH Studies for Poorly Soluble Drugs Accelerates Dosage Form Development, Manufacturing and Supply for Patient POC Trials

From Computational Predictability to Verification of Anti-Solvent Precipitation Process, Solid State Characterization, and In Vitro Dissolution of a Weakly-Basic Nanoamorphous Micellar Dispersion

Hot Melt Extrusion Process Optimization and Formulation Development of Amorphous Solid Dispersions for a Poorly Soluble Calcium Channel Blocker

Impact of pH and Ionization State on Limit of Congruency (LoC) of Drug and Polymer Release from Amorphous Solid Dispersions

Impact of Storage Conditions on the Physical Stability of Indomethacin-PVP Amorphous Solid Dispersions

Improving the Stability of a Spray-Dried Peroxide-Susceptible Drug in Tablets

Improving Thermal Conductivity Expands KinetiSol^® Processing Capabilities of Amorphous Solid Dispersions

Increasing the Apparent Solubility of Niclosamide by Hot-Melt Extrusion Processing

Influence of Pharmaceutical Polymers on the Recrystallization and Dissolution of Nimodipine

Investigating the Applicability of the Molecular Descriptor R3m in Predicting Amorphous Solid Dispersion Formation for Thermally Unstable APIs

Investigation of Taste Masking Efficiency of Caffeine Citrate by Lipids Utilizing Hot Melt Extrusion Technology

Manufacture of Amorphous Solid Dispersions by Spray Drying Using a Coaxial Three-Fluid Nozzle

Mechanistic Understanding of Drug-Rich Nanodroplet Size Stabilization by Surfactants using ¹H NMR

Molecular-Level Characterization of Amorphous Pharmaceuticals from MAS NMR

Optimisation of Oral Bioavailability of Indomethacin Tablets via Dielectric Heating Techniques

Organic Glasses with Tunable Liquid-Crystalline Order Through Kinetic Arrest of End-Over-End Rotation

Polymer Nanocoating of Amorphous Drugs for Improving Stability, Dissolution, Powder Flow, and Tabletability: The Case of Chitosan-Coated Indomethacin

Role of Lattice Disorder in the Water Mediated Dissociation of Pharmaceutical Cocrystal Systems

Selective Laser Sintering Based 3-Dimensional Printing as a Single Step Process to Prepare Amorphous Solid Dispersion for Improved Bioavailability

Solid State Investigation of KinetiSol® Processed Abiraterone Solid Dispersions

Solid-State Stability and Dissolution Performance of Lumefantrine Amorphous Solid Dispersions Formulated with Neutral and Enteric Polymers

Structure – Mechanics Study of Drug-Drug Cocrystal for Enhancement of Tablet Performance and Size Optimization of Metformin HCl

Surface Diffusion in Molecular Glasses: Effects of Molecular Shape, Penetration Depth, and Ambient Moisture

The Enhancement of the Aqueous Solubility of Albendazole Employing Polymeric Amorphous Solid Dispersion (ASD) as an Approach

The Impact of TPGS and PEG 1000 as Surfactants in a Spray Dried Ternary Amorphous Solid Dispersion on Glass Transition Width and Miscibility

The Impact of TPGS on Solid State Stability in a Spray Dried Amorphous Solid Dispersion

The Molecular Descriptor R3m Correctly Predicts the Dispersability Behavior of Highly Supersaturated Systems

The Unexpected Consequence of Drug-Polymer Interactions on Dissolution of Amorphous Dispersions

Understanding the Impact of Phase Separation on Drug Absorption

Understanding the Impact of Surfactants on the Phase Separation Behavior of Amorphous Solid Dispersions

Applying Electron Paramagnetic Resonance Spectroscopy to Assess the Stability of Polymers During Hot Melt Extrusion

Bioadhesive Nanoemulsions Improve Piplartine Cytotoxicy in 3D Breast Tumor Models and Reduce Tumor Development In Vivo upon Intraductal Administration

Building a Better Particle: Leveraging Physicochemical Understanding of Amorphous Solid Dispersions and a Hierarchical Particle Approach for Improved Delivery at High Drug Loadings

Comparative PK Performance of Solution and Suspension Based Formulations for a BCS Class II Molecule in a Soft Gelatin Based Dosage Form

Effect of Drug Loading on In Vitro and In Vivo Performance of KinetiSol® Processed Abiraterone Solid Dispersions

Effect of Particle Size of API on Critical Quality Attributes of Oral Films

Excipient-Mediated Concomitant Increase of Both Solubility and Permeability: Cremophor and Pluronic L44 Based Formulations for Increased Oral Absorption of Lipophilic P-gp Substrates Drugs

Formulation of a Topical Gel of Cromolyn Sodium for Treatment of Atopic Dermatitis

Influence of Process Parameters in Establishing the Microstructure Equivalence as a Q3 Function in Developing a Topical Antibacterial Gel Equivalent to Marketed Reference Listed Drug Product

Nanoparticle Based High Drug Load Amorphous Solid Dispersions Produced by Spray-Drying

PBBM Analysis of the In Vivo Behavior of Amorphous Solid Dispersions Based on Water-Soluble versus Water-Insoluble Carriers: A Fenofibrate Case Study

Polymorphism Influences the Physicochemical Characteristics of Anti-Tuberculosis Drugs Formulated as Nanocrystals

Rapid Development and Pharmacokinetic Evaluation of Amorphous Solid Dispersion with Minimal Material Use

Solubility Enhancement of Poorly Soluble Drugs Using EUDRAGIT^® L 100-55

Two Strategies of Using Acidic Polymers to Improve Stability and Dissolution of a Basic Amorphous Drug Clofazimine

Using Microevaporative Screening Studies in Development of Amorphous Dispersions for Phase I Clinical Trials

A Stabilized Pemetrexed-Containing Liquid Formulation for Injection

Anomalies in the pH-Dependent Supersaturation of Telmisartan

Application of Sucrose Acetate Isobutyrate for Development of Methamphetamine Abuse Deterrent Formulations

Challenges in Solubility Measurements: New Techniques and Methods for more Accurate Results

Development of a Quantitative Method to Evaluate the Printability of Filaments for Fused Deposition Modeling 3D Printing

Effect of Process and Glycerol Palmitostearate on Stability, Crystal Polymorphism and Dissolution of Rifaximin Tablets

Particle Analysis within Drug Products: Novel Methods in Quantification using 3D Microscopy

Potential for Levothyroxine Sodium Pentahydrate to Dehydrate in a Drug Product Environment: Implications on Chemical Stability

Solubility and Stability Enhanced Prednisolone Acetate Solutions

Solubility Enhancement of Etoricoxib by Co-solvents

Studying Binding Interactions of Drugs to Macromolecules Using an Ultrafiltration Method

Temperature and Humidity Degradation of API’s Studied by Dynamic Vapor Sorption and In Situ Raman Spectroscopy

A New Abuse-Deterrent Index for Narcotic Drug Formulations

Biodegradable Hydralese^TM (PGSU) (poly(glycerol sebacate) urethane) Microspheres for Controlled Drug Delivery

Cholecalciferol Complexation with Hydroxypropyl-β-Cyclodextrin (HPBCD) Phase Solubility and Molecular Dynamics Simulation

Comprehensive Binder Comparison for ODT in Dry Manufacturing Processes

Correlation between Mucoadhesion and Surface Energy Properties of HPMC Compacts

Creation of Filaments for 3D Printing via Hot Melt Extrusion: Evaluating Different Downstream Technologies

Development of a Predictive Model for the Impact of Polyethylene Glycol Molecular Weight and Blend Ratio on Topical Ointment Microstructure and Performance

Effect of Hypromellose Particle Size on the Interfacial Bonding and Mechanical Strength in Extended Release Metformin Bilayer Tablets

Effect of Polymer Source Variation on Physicochemical Properties of Risperidone Microspheres

Expanding Hot Melt Extrusion Design Space of Amorphous Solid Dispersions by Incorporation of Thermally Conductive Excipients

Freeze-Drying of Hydroxypropyl-β-Cyclodextrin-Acetazolamide Formulations – Impact of Freeze-Drying Process Parameters

How to Enhance Your Tablet Coating Formulation Development by Using a Particle Engineered Polyvinyl Alcohol

Influence of Plasdone^TM S630 Ultra, an Improved Copovidone Grade, on the Oxidative Degradation of Quetiapine Fumarate Amorphous Solid Dispersions Prepared Using Hot Melt Extrusion

Investigation of Taste Masking Efficiency of Different Polymers via the Hot Melt Extrusion Technique

Low-Cost Enteric Spray Coating System for Dietary Supplements

Pharmaceutical Lauryl Sulfate Salts – Prevalence, Precipitation Rules, and Formulation Implications

Phosphorus Content of Medicines Taken by Patients on Hemodialysis and Its Relation to Serum Phosphate Concentration

Preparation and Characterization of the Nano-Capsules Based on the Inter-polyelectrolyte Complexes for Controlled Perfume Release Systems

Preparation of 3D Printing Tablets by Fused Deposition Modeling using Shin-Etsu AQOAT^®

Processability and Stability of Plant-Based Dextrin as a Dry Binder in Tablets Prepared by Direct Compression

Stability Improvement of the Moisture Sensitive Drug Ranitidine HCl with the Inclusion of Partially Pregelatinized Starch (Starch 1500)

Structure-Function Analysis of Advanced Lipid-Based Excipients and Correlation with Stable Product Performance

To Evaluate the Effect of Material Grades on Physicochemical Properties of Topical Cream Formulation using Design of Experiments (DOE)

Topical Gel: Influence of Excipient Ratio and Process Parameters in Establishing the Microstructure Equivalence as a Q3 Function in Developing a Generic Equivalent to Marketed Product

Fixed Dose Combination of Metformin ER and Glipizide IR Bilayer Tablets using Directly Compressible Excipients

Amikacin Extended Release Nanoliposomes Using the Ethanol Injection Method: Development and Characterization

Amorphous Solid Dispersions for Nasal Delivery: Development, Characterization and Aerodynamic Performance

Expanding Global Tuberculosis Treatment Through a Novel Inhaled Clofazimine Product

Formulation and Evaluation of Doxorubicin HCl Nanoliposomes by Ethanol Injection Method

In Vitro Characterization of Gentamicin Sulfate Loaded PLGA Magnetic Nanoparticles Intended for the Pulmonary Treatment of Hospital Acquired Pneumonia Caused by Pseudomonas aeruginosa

Nasal Delivery of Insulin by Self-emulsified Nanoemulsion

3D Powder Bed Printing of Lactose Tablets

A New High Throughput poly(meth)acrylate Based Ready-to-Mix Powder for Oral Immediate Release Applications

Case study – Application of Colorista® Capsules for Rapid Product Development with Proof of Concept Data for a Heat, Oxygen, and Moisture Sensitive Compound

Chemometric Assisted X-Ray Powder Diffractometry Method for Crystalline Lopinavir Quantification in 3D Printlets Manufactured by Selective Laser Sintering

Creation and Assessment of Solid Crystal Suspensions of Carbamazepine utilizing Crystalline Carriers via Hot-Melt Extrusion Techniques

Developing a High API Load Immediate Release Tablet by Switching from a Wet to a Dry Granulation and DoE Formulation

Development of a High Shear Wet Granulation Process through the Use of Design of Experiments

Development of Bioequivalent Pazopanib Tablets Using Quality by Design Approach and Comparative Pharmacokinetics in Beagle Dogs

Development of High Drug Load Multiparticulate Beads Using Extrusion-Spheronization Process

Enhanced Solubilization of an Analgesic/Antipyretic Drug with the Use of Polymeric Excipients

Formulation Development of Loratadine Immediate-Release Tablets Using Hot-Melt Extrusion Coupled with 3D-Printing Technology

Improvement of Drug Powder Flow Properties by Dry Particle Coating

Orally Disintegrating Tablet Formulation Development Through Functional Excipients

Overdose and Alcohol Sensitive Immediate Release Sleeping Pills (OASIS) for Deterring Accidental Overdose or Abuse of Sleeping Pills

Scale-Up and Stability of Ibuprofen Tablets Containing StarTab®, Directly Compressible Starch

Tableting of Nanoformed Material

Taste Masking of Drug Layered Pellets with the Kollicoat^® Smartseal 100P

The Application of Mixture Design to Develop Directly Compressible PVP K29/31 SDD Tablet Formulation Platforms

To Determine the Dosing Disk and Encapsulation Speed for Encapsulation of a Drug Product Using Automated Encapsulator (Bosch 1700)

Utilization of Adsorption Nature of Neusilin US2 in the Formulation of Liquisolid Compacts of Practically Insoluble Drug

Controlled Release of an OTC Cough Suppressant in a Soft Gelatin Based Dosage Form

Determining the Design Space of Intermediate Core Microparticles Obtained from Spray Dried Acrylic Polymers for Taste Masking Bitter Drugs

Development of a pH-Dependent Colon Targeted Drug Delivery System for Mesalamine Delayed Release Tablets

Development of Patient-Focused Drug Delivery System by Modulated Structure Designs Using 3D Printing Technologies

Evaluation of Various Formulations and Processes on Barrier Membrane Coating of a BCS Class 1 Drug using Aquacoat^® ECD-30

In Situ Alginate Crosslinking for Gel Strength Enhancement in the Formulation of High Drug Load Gastroretentive Tablets by Direct Compression

In Vitro Evaluation of an Enteric Coating System for Esomeprazole Delayed Release Multiparticulates for Administration Through Nasogastric Tube

Influence of Polymer Chemistry in Drug Release of Propranolol HCl Controlled Release Tablets Manufactured via a Direction Compression Method

MED^TM 3D Printing- A Technology Platform for Accelerating Formulation Development

New Directly Compressible Controlled Release Excipient: Effects of Tablet Design and Formulation Variables on Melatonin Release

Novel Uncoated Enteric Two-Piece Hard Capsule by Cold Gelling Method - Part 2

Physical Manipulation of Opioid Drug Product Containing Combination of Opioid Agonist and Antagonist

Postprandial Enteric Performance of Enteric Coated Omeprazole Multiparticulate Systems

Taste-Masking Efavirenz through Microencapsulation Using the Technique of Spray-Drying

The Influence of Compacted Dry Granules as Filler on Development and Manufacturing Ability of Multi-Unit Pellet System (MUPS) Tablet

Accelerated Formulation Characterization and Development with AI Image Analysis and Image-Based Release Modeling for PLGA Implant

Development of First Generation ALK Inhibitor Liposomal Formulations for Enhancing Anti-Cancer Activity

Formulation Optimization of PLGA Microspheres Prepared Using a Coacervation Method

Formulation, Characterization, and the Diuretic Effects of a New Intravenous Metolazone Emulsion

A Hierarchical Mass Transfer Model for Drug Particle Dissolution

Accelerated Stability Assessment for an Oral N-type Calcium Channel Blocker

Application of Computational Machine Learning Tools to Compare Predictive Performance on Critical Quality Attributes of Spray Dried Lipid-based Formulation

Simulating Polymer Controlled Drug Release from Amorphous Solid Dispersions within a Physiologically Based Pharmacokinetic (PBPK) Framework: Case Example Ritonavir Norvir^® Tablet

An Innovative HPLC Assay for Use in Formulating an Extended Release Testosterone Transdermal Patch

Crystal Structure Solution for Terfenadine Allows Prediction of Its Mechanical Disordering during Milling

Development of Sustained Release Lipid-Based Matrix Microparticles for Vaginal Delivery using Twin-Screw Hot Melt Extrusion

High Temperature Measurement of API Solubility in Spray Drying Solutions by NMR

Physical Properties of Foam Formulations and Their Disappearance Time and Palatability in the Oral Cavities of Healthy Volunteers

Solubility-Physicochemical-Thermodynamic Theory of Penetration Enhancer Mechanism of Action

Topical Formulation Approaches: Solubility Complexities for BCS Class II Drug Substances (High Permeable/Low Soluble)

Topical Formulation Development: Role of Release modulators, Anatomical Site, and Gender on Skin Permeation of a Model Drug-In Vitro Assessments

A Multifunctional Orodispersible Film System with Hydroxypropyl-β-Cyclodextrin

In Vitro Evaluation of Nephrotoxicity and Permeation Studies on Vancomycin Loaded Liposomes

Correlation of Physical and Structural (Q3) Properties of Lidocaine/Prilocaine Topical Products with Product Performance In Vitro and In Vivo

Disparities versus Similarities; WHO GPPQCL and ISO/IEC 17025:2017, International Standards for Quality Management Systems in Pharmaceutical Laboratories

Impact of Excipient and Blend Properties on Feeding Consistency for Continuous Manufacturing

Stabilizing Polysorbate 20 and 80 Against Oxidative Degradation

Evaluation of Phospholipase B-Like 2 (PLBL2) Testing as Downstream Process Host Cell Protein (HCP) Impurity Control Strategy for PS-80 Degradation

Utilizing Two PCR Technology Platforms to Support Biosafety and Release Testing of Recombinant Adeno-Associated Virus (rAAV) Vectors for Gene Therapy

Characterization of large conjugate (PEGylated) biologics: Combination approach with CE-SDS and SEC-MALS methods

Feasibility of Implementation of USP < 855 > Nephelometry and Turbidimetry Suitability Verification/Validation for Proteins

Impact of Uneven Illumination in Flow Imaging Flow Cell on the Sizing Accuracy of Beads and Implication for Biopharmaceutical Drug Products

Ph.Eur. Visual Color Method I versus Method II Robustness Comparison

Application of Slope Spectroscopy® to the Measurement of Co-oximetry Parameters in Bovine Hemoglobin: The Case of Measuring Low Concentration Met Hemoglobin in Bovine Hemoglobin Samples

Automatic Continuous Measuring Method for Sub-micrometer Protein Aggregation Size Distribution using 3D Homodyne Light Detection (3D-HLD)

Targeted HCP Quantitation Workflow Utilizing Versatile LC-MS Methodologies

Using HR Multi-attribute Method to Monitor and Compare pCQAs of Innovator Rituximab and Its Biosimilars

Application of an Impedance-Based Freeze-Drying Microscope (Z-FDM) for Product Formulation Development and Screening

Impact of Formulation and Processing on Critical Quality Attributes of siRNA Encapsulating Lyophilized Lipid Nanoparticles

Lyophilization: Small-Large Scale Comparability

Inline Blend Uniformity (BU) Monitoring of Low Drug Loading Formulations using Light Induced Fluorescence (LIF)

Particle Identification and Source Analysis

Non-Biological Quantification of Viral Titer: A New Approach

Exploring Enhanced Selectivity of an Innovative Ion Exchange Resin in ADC Polishing

Quantification of Apoptotic Dye Defined Viable Cell Density using Dielectric Spectroscopy and Multivariate Data Analysis

Developing a Multiphase Coupled CFD-DEM Model for a Fluidized Bed Dryer

Discrete Element Modeling of a Pharmaceutical Blending Process

Optimization of Spray Drying of Mucoadhesive Microparticles Using Design of Experiments (DoE)

Optimization of Final Filtration Operations using Single-Use Systems

Biphasic Dissolution Study of Nifedipine Extended-Release (ER) Tablets for Biorelevant Testing

Development of an In Vitro Drug Release Method to Enable In Vitro-In Vivo Correlation of Potassium Chloride Extended Release Tablet

Evaluating Dissolution Profiles of Different Non-prescription Niacin Formulations Intended to Reduce Cutaneous Flushing and Hepatotoxicity Adverse Events

Evaluation on Biorelevant Dissolution Behavior of Propranolol HCl Encapsulated in Various Capsules

Development of Accelerated Release Testing Method for Levonorgestrel Intrauterine Systems

Dissolution Development of Parvulet™ Technology Oral Tablets

Predictive Dissolution for Nanoparticle Formulations

Method Validation for Quantitative Determination of the (Pseudo) Polymorphs Ratio in DS and DP Samples: Performance and Compliance

Simultaneous Estimation of Paclitaxel and Erlotinib in Plasma by LC-MS/MS (Liquid Chromatography/Electrospray Tandem Mass Spectrometry): Application in Formulation Development and Pharmacokinetics

Development of an In Vitro Release Testing Method for Rectal Suppositories

Determination of Calcium Carbonate Content in a Film Coating Using Ultra High Performance Liquid Chromatography-Charged Aerosol Detection

Fundamental Evaluation of Moisture Scavenging Property of Partially Pregelatinized Maize Starch using Thermoanalytical Techniques

Accelerated Forced Degradation of Therapeutic Peptides in Levitated Microdroplets

Photo-Oxidation Mechanisms in Liquid Formulations: Thinking Beyond Peroxide and Free Radical Induced Degradation

Chiral HPLC Method to Determine the D-/L-Epinephrine Ratio in Expired Epinephrine Autoinjectors

Reliable Quantitation of Nitrosamine Impurities using High Resolution and Accurate Mass Orbitrap Mass Spectrometry

Temperature-Dependent Formation of N-nitrosodimethylamine (NDMA) during the Storage of Ranitidine Reagent Powders and Tablets

Utilizing the Power of GC Column Deactivation to get Symmetric Peaks for Residual Volatile Amines and Genotoxic Impurities in Pharmaceutical API

Mycotoxin Screening in Nicotine-Containing Products with LC-MS/MS

Development of an Analytical Method to Quantify Warfarin Enantiomers using Direct Chiral AGP-HPLC-DAD: Application to Human Plasma Samples from Patients Receiving Anticoagulation Therapy

Influence of Polymeric Excipients on the Precision of Particle Size Distribution Measurements of Suspensions Using Laser Diffraction

Online Identification and Quantification of Structural Isomers Using In Situ Fourier Transform Infrared (FTIR) Spectroscopy during Pharmaceutical Manufacturing

Structural Analysis of Pharmaceuticals by Stochastic Differential Scanning Calorimetry

Analysis of Pharmaceutical Raw Materials Using the Tri-range Spectrum 3 Infrared Spectrophotometer

Characterization of Mechanical Properties of Sodium Alginate Raft Using Rheometer

Classification of Commercially Available Ofloxacin Tablets Using Frequency-Domain Terahertz Spectroscopy and Discriminant Analysis

Development and Validation NMR Method for Identification and Assay of Bulk Drug Substance Pregnenolone

Enhancing the Efficiency of USP Monograph Workflows through the Use of Dual-Injection UHPLC

Examining Surface Interactions of Glycine and Its Oligomers from Experimental and Molecular Modelling Approaches

Instrument Calibration Verification and Method Transfer for a Low-Cost Handheld Short-Wave Infrared Spectrometer for Rapid Qualitative Evaluations of Pharmaceuticals

Investigating the Sensitivity of Ultrasonic In-Die Measurements to the Compaction Behavior of Different Mannitol Grades

Investigation of Rheological Behavior of Diclofenac Topical Gel Formulations Using Rheometer

A Simple TLC-UV Spectrophotometric Method for Rapid Assessment of Quality of the Fixed-Dose-Combinations Lamivudine/Tenofovir Disoproxil Fumarate and Lamivudine/Zidovudine Tablets

Characterization of Commercial Poly(lactide-co-glycolide) by NMR Spectroscopy

Infrared Analysis of Pharmaceutical Packaging

Innovations in Drug Quality: Quantification of APIs in Contraceptive Tablets by Thin Layer Chromatography with Smartphone Image Capture and Image J Analysis

Comparison of Analytical Techniques for Measuring Crystallinity and Drug-in-Polymer Solubility in Amorphous Solid Dispersions

Determination of Saturation Solubility of Clotrimazole in Different Fatty Alcohols Using Differential Scanning Calorimetry (DSC)

Development of Particle Size Methodology for a Nano Particle Suspension of Megestrol Acetate

Investigation of Anti Reflux Suspensions for Raft Properties: Effect of Varying Key Ingredients & Novel Method of Raft Strength Determination

An Effort at Improving Reliability of Laboratory Data in Titrimetric Analysis for Zinc Sulfate Tablets Using Validated Spreadsheet Calculators

Spray Drying with a Coaxial Three-Fluid Nozzle: Practical Aspects and Physico-Chemical Product Properties

Effect of Alkalizing Agent on In Vitro Drug Release from Bilayer Abuse-Deterrent Extended-Release Tablets to Minimize Oral Multiple-Dose Abuse of Opioids Using Propranolol HCl as a Model Drug

Establishment of Design Space for Liposomal Continuous Manufacturing Platform

Manufacturing Lumefantrine Amorphous Solid Dispersions with Spray Anti-solvent Precipitation Method

Surface Preparation and Its Effect on Sticking

Flood Feeding Small Batches on a Co-Rotating Intermeshing Twin-Screw Extruder.

Optimize Spray Pattern using a Replicated 2³ Full Factorial Design of Experiments

Preventing Compounding Mistakes in 503A Pharmacies: An Exhibition of Quality Assurance Program in Pharmaceutical Compounding

Application of Drug-Layered Core Particle in Orally Disintegrating Mini-tablets for Pediatric

Polyglycerol esters of Fatty Acids on the Development of Inhalable Lipid-Based Microparticles via Spray-Drying

A Quality by Design Approach to Optimize Tablet Formulations Containing PVP VA64 Amorphous Dispersions: Part I, Formulation Variables

Addressing the Scale Up Challenge of a Low-Dose Tablet Formulation through Blending and Roller Compaction Optimization

Benchmarking Formulation and Process Approaches to Poorly Flowing Spray Dried Dispersions for Downstream Processing

Continuous Manufacturing - How to Overcome Feeding Challenge of Magnesium Stearate

Development of Gastro-Retentive Floating Tablets Using Fused Deposition Modelling 3D Printing

Exceptional Tabletability of Elastic Crystals – Decoupling Single Crystal Mechanical Behavior from Powder Tableting Performance

Scaling up Fluidised Bed Coating of Sustained Release Microparticles at High Spray Rate Using the MicroCoat^TM Technology

Studies on In Vitro In Vivo Correlation of a BCS IV Drug Tablets by a Discriminatory Dissolution Method

Superior Lubrication Performance of Sodium Stearyl Fumarate in Direct Compression and Continuous Manufacturing

Determination of Trace Amounts of N-Bromosuccinimide in N-Chlorosuccinimide

Salt Screen of Bedaquiline Using a Combination of Orthogonal Techniques to Identify Promising New Salts for Development

Advanced Analytical Tools for Characterization of Pentosan Polysulfate Sodium

Artificial Neural Network as a Predictive Tool for Continuous Processing of Liposomes

Establishing a Proactive Behavior Through Method Lifecycle: Method Performance Verification Contribution

Efforts at Building Capacity for Manufacturing and Analysis Laboratories for Medicines in Sub-Saharan Africa; Historical Evidence from the BIRS Program

Investigation of the Drying Process of Pharmaceutical Wet Granules in a Fluidized Bed Dryer using Coupled CFD-DEM Approach

A Novel Granulation Process For Powder Bed-Based 3-Dimensional Printing Applications

Application of PAT Tools in Exploratory Drug Product Development

Designing a Quick Response (QR)-Coded Orodispersible Film Using 3D Printing Technology

In-line Measurement of Moisture Using an NIR Filter Photometer in Rotor Processor: Part II

Methanol-Assisted Secondary Drying to Accelerate Residual Solvent Removal in Spray Dried Polymers

CPM Technology for Bottom Up and Top Down Nanoparticle Production in Single Set-Up

Feeder Performance of Benecel™ PH DC HPMC for Continuous Manufacturing of Controlled-Release Dosage Forms

Flow Properties, Morphology and Compression Characteristics of Directly Compressible Starch Before and After Feeding through Continuous Feeder

In-line Assessment of Powder Stream Density Variation and Its Effect on Near Infrared Measurements during Scale-Up of a Simulated Continuous Process

Investigating the Effect of Process Parameters of the Dome-Ex Twin-Screw Granulator on Particle Size and Particle Size Distribution

Polymorphic Discrimination via Powder Brillouin Light Scattering

Encapsulating Low Viscosity Products Using Liquid Filling and Banding Technology

Extended Multidisciplinary Investigation Leads to Efficient Optimization of a Manufacturing Process of Clinical Drug Product Avoiding Critical Degradation Issues

Where Does Drug Degrade during Twin-Screw Melt Granulation?

In-line Measurement of Moisture Using an NIR Filter Photometer in Rotor Processor for Dry Powder-layering: Part III

The Influence of Binder Addition Methods on Continuous Twin-Screw Melt Granulation

Impact of Manufacturing Process on Critical Quality Attributes of Multivesicular Liposomes

The Optimization of Process Analytical Tools for The Inline Continuous Quantification of Multiple Drugs in Fixed Dose Combinations

A Quality by Design Approach to Optimize and Accelerate Formulation and Process Development Leading toward Registration Batches Manufacturing

Evaluation of a Quality by Design (QbD) Approach for Process Development and Scale-Up of a Novel ALS Drug Product

Investigating the Use of Absolute Exhaust Humidity as a Control Parameter for Multiparticulate Coating

Study of Spray Drying Process Parameters and Equipments on the Granule Characteristic of the Immediate Release Tablets of a BCS (Biopharmaceutical Classification System) Class –II Drug

Is Derivatization Necessary for the Gas Chromatographic Analysis Performed in Extractable/Leachable Screening Studies?

Evaluation of Albumin Binding for Fatty Acid Modified Peptides

Development and Characterization of a Transgenic Mouse Expressing P-glycoprotein at the Choroid Plexus

Intranasal Delivery of Insulin by Self-emulsified Nanoemulsion System: In Vitro and In Vivo Studies

The Impact of Albumin Binding on PK of Fatty Acid Acylated Peptide and Estimation of In Vivo Albumin Binding Affinity

Impact of Low Intensity Focused Ultrasound on Tracer Accumulation across BTB in Breast Cancer Metastases to the Brain

Use of Chrom logD-Assay for Lipophilicity Estimation and Permeability Binning of Targeted Protein Degraders/Protacs

Biopharmaceutical Characterization and the Importance of Mucus Binding in Segmental-Dependent Intestinal Permeability of Rebamipide

Complex Formation of an Engineered Anti-OX40 IgG RGY Hexamer with Complement C1q Contributes to its Fast Clearance in Mice

InTESTine Barrier Chip: A Medium Throughput Microfluidic System to Study Drug Absorption and Host-Microbe Interactions in Ex Vivo Intestinal Tissue

Mechanistic Insights and Pharmacokinetic Modeling of the Peripheral Sink Effect in Alzheimer’s Disease Immunotherapy

Exosome-Transfer of miR-6068 Mediates the Aggressive Phenotypes of Prostate Cancer Cells

FirePlex-HT® – A Novel Assay Platform which Combines High-Throughput, Multiplexing, and Absolute Quantification

TMTC4 is a Novel Biomarker and Potential Therapeutic Target in Prostate Cancer

Assessing the Cerebrovascular and Neurological Impact of Chronic Smoking on Post-Traumatic Brain Injury Outcome: An In Vitro Study

Effects of Monocyte Chemoattractant Protein-1, Macrophage Inflammatory Protein-1α and Interferon-α2a on P450 Enzymes in Human Hepatocytes In Vitro

Characterization of Toxicity and Physiological Effects of Cocaine Metabolites to Identify Promising Therapeutic Enzyme Candidates for Cocaine Overdose Treatment

Antioxidant Effects of N-acetylcysteine Amide and NPI-002 on Human Skin or Equivalents

Biodistribution and Tumor Targeting of an Anti-IL13 Receptor α2 Antibody by Positron Emission Tomography (PET) Imaging in A375 Xenograft Model

Bone-Targeted Angiotensin Peptide Therapy in Adjuvant Arthritic Rat: Impact on the Lung Renin-Angiotensin System Components

High-Throughput, Reproducible Scale-Up Manufacturing of Decreased Nonspecific Adhesivity, Receptor-Targeted (DART) Nanoparticles for Clinical Translation

Leveraging mRNAs Sequences and Nanoparticles to Deliver SARS-CoV-2 Antigens In Vivo

Phospholipid-Based Cyclosporine Prodrug as a Novel Targeted Drug Delivery in IBD

Direct Targeting of BRD4 by Novel PROTAC Nanoparticles Inhibit High-risk Neuroblastoma Growth

Intrapulmonary Inoculation of Multicellular Tumor Spheroids to Construct an Orthotopic Lung Cancer Xenograft Model

Statins Relax Systemic Mesenteric Arteries via the Inhibition of Phosphodiesterases

A Novel Pharmacotherapy Approach That Combines Ivermectin and a Hepatoprotective P-Glycoprotein (PGP/ABCB1) Efflux Inhibitor to Reduce Alcohol Drinking and Preference in Mice

Does Drug-Lipid Binding Add Up? A Surface Plasmon Resonance Study into Combined Phospholipid Liposome Binding and the Impact of Cholesterol

Ex Vivo Dermis Microdialysis: Method Development and Testing

Dermal Pharmacokinetics of Lidocaine, Prilocaine and Their Metabolites from Topical Dermatological Drug Products

Effect of Multidrug Efflux and Uptake Transporters and CYP3A on the Pharmacokinetics and Tissue Distribution of Milciclib

Micro-Pharmacokinetic Analysis of Drug-Induced Splenomegaly in Mice

A Potential Method to Adjust Kp Scalar in Different Species for PBPK Modeling

Comparison of Different Brain Vascular Volume Correction Techniques while Measuring Brain Uptake of Sucrose

Development and Validation of Efinaconazole HPLC Method in Human Nails

Evaluation of Pharmacokinetics and Dose Proportionality of R14 After Intravenous Administration in Rats

Evaluation of Serial Survival Cerebrospinal Fluid Collection in Intact or Jugular Vein‑Cannulated Rats and of Intrathecal Dose Administration to Intact Rats

In Vivo Pharmacokinetic Characterization of CK-3773274, a Novel Cardiac Myosin Inhibitor

Modeling the Impact of Amorphous Drug-Polymer Colloids on the Absorption of Poorly Water Soluble Drugs

Pharmacokinetic Variations of Riluzole and Etoricoxib between Sprague-Dawley and Long-Evans Rats

Topical Ocular Pharmacokinetics and Bioavailability for a Cocktail of Timolol, Betaxolol and Atenolol in Rabbits

Discerning Characteristics of Endogenous Compounds during Drug Screening Process

Human Liver Microsomes on Magnetizable Beads: A Potential Tool to Study In Vitro Drug Metabolism

Using In Vitro Skin Irritation Testing for Dose Optimization: A De-risking Approach for Topical Ointments

Quantitative Systems Toxicology Identifies the Mechanism and Data Gaps for Evaluating the Hepatotoxicity of Compound V

LC-MRM-MS Method for the Detection and Quantification of Six Nitrosamine Impurities in Sartan (ARBs) Drugs

Deep Learning on High-Throughput Transcriptomics to Predict Drug-Induced Liver Injury

Physiologically Based Pharmacokinetic Modeling of Brain for Prediction of Local Target Site Concentration in Rat

Impact of Bulk Flow Mediated Efflux on Brain Uptake Measurements of a Small Molecule Marker Having Low Permeability: Comparison Across Age and Sex