Associate Director of Pharmaceutical Product Development Triastek, Inc. NANJING, Jiangsu, China (People's Republic)
Presentation Description: Melt Extrusion Deposition(MED) 3D printing is a technology that converts powder feedstocks into softened/molten states followed by precise layer-by-layer deposition to produce objects with well-designed internal geometric structures. This technology can be used to create drug delivery systems with predetermined release characteristics, accelerate the product development and build an advanced manufacturing system. The MED process continuously transforms API/excipient powders into final products within one integrated system, thereby enabling end-to-end automation. In this presentation, a newly developed MED-based 3D printing system for tablet continuous manufacturing is discussed. Various design elements including PAT, SCADA, robotization, and traceable ID have been implemented into the modular system to ensure the quality of every tablet produced. Such a CM line is capable of producing dosage forms with various modified release characteristics, and is amenable for production scaling through chaining of modularized printhead units, thus streamlines the translation of formulations from early-phase development to commercial production.
Upon completion, participant will be able to understand the principle of MED 3D Printing technology and its key features for pharmaceutical applications
Upon completion, participant will be able to understand how the well-designed MED 3D printing system enables tablet continuous manufacturing and assures high product quality
Upon completion, participant will be able to recognize the capability and flexibility of MED 3D printing system to manufacture dosage forms with various modified release characteristics