Assoc./Full Professor University of Bath Bath, England, United Kingdom
This presentation is being submitted as part of a larger 2-hr symposium on 'Pediatric Biopharmaceutics," with each seminar being submitted to the AAPS programming committee by a different individual. The presentation will focus on the use of in vitro biopredictive testing and physiologically-based pharmacokinetic modelling for the prediction of in vivo performance in paediatrics. The presentation is a critical part of the proposed session as it will tie together with the other proposed presentations for this symposium.
understand the use of PBPK modelling to assess the performance for pediatric drug products.
understand the use of biorelevant in vitro testing to assess the performance for pediatric drug products
design drug products for pediatric patients with a holistic understanding of the characteristics of the pediatric population