17 - Dissecting the "3-Ds": Decontamination, Degradation and Deactivation of Hazardous Drugs
Tuesday, April 7, 2020
5:00 PM – 6:30 PM
Location: Colorado B-D
Decontamination of hazardous drugs (HDs) such as chemotherapy agents and Beta-lactam antibiotics from surfaces in compounding areas is essential to reduce the risk of cross-contamination and occupational exposure. Understanding the roles of physical removal versus degradation or deactivation of the parent drug is critical for proper selection of decontamination agents, cleaning techniques, and for proper interpretation of wipe sampling for residues. This session will discuss data that support physical removal vs. degradation, and the challenges associated with HD decontamination and sampling.
Define the terms cleaning, decontamination, degradation, and deactivation of hazardous drugs.
Interpret the results of data from manufacturers of decontamination agents and from environmental wipe sampling to make informed decisions about how to establish and maintain a state of control.