9 - Chronic Traumatic Encephalopathy (CTE) and the Long-Term Consequences of Sports-Related Repetitive Subconcussive Brain Trauma: What We Know Now and What We Need to Know Next
Thursday, October 15, 2020
3:30 PM – 4:30 PM ET
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Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease found in individuals with a history of exposure to repetitive head impacts (RHI), such as former American football players, soccer players, and boxers. Referred to as “punch drunk” or dementia pugilistica since the early 20th century, the term “CTE” has been used since the 1950s to describe the clinical and neuropathological changes seen in individuals with RHI exposure. However, it is only in the past decade that CTE has received increased attention due to a growing number of deceased former NFL players being diagnosed with the disease postmortem. The tremendous growth in media attention to CTE has led to many misconceptions and misunderstanding about CTE. As with other neurodegenerative diseases, at this time CTE can only be confirmed by neuropathological examination. However, there are now consensus diagnostic criteria for the clinical presentation of CTE, and there have been several studies indicating potential neuroimaging and fluid biomarkers to detect and diagnose CTE during life. This workshop will provide an overview of what is currently known about CTE and what knowledge gaps exist, as well as current and future directions in research.
Describe the neuropathological features of chronic traumatic encephalopathy (CTE).
Explain what is currently known about risk factors for developing CTE.
Discuss the clinical features associated with CTE and the current diagnostic criteria for Traumatic Encephalopathy Syndrome.
Describe the possible fluid and neuroimaging biomarkers for CTE.
Explain the current gaps in knowledge about CTE and what research is needed to close those gaps.