Concurrent - Modeling Development and Disease: Neural

Thursday, June 25, 2020

11:00 – 12:45 EDT

Sponsored By: MaxWell Biosystems

Chair(s)

Joseph Klim

Department of Stem Cell and Regenerative Biology
Harvard University, USA
Maria Kousi

Department of Computer Science and Artificial Intelligence
Massachusetts Institute of Technology (MIT), USA
Marine Krzisch

Jaenisch lab
Whitehead Institute for Biomedical Research, USA
Larissa Traxler

Institute of Molecular Biology
University of Innsbruck, Austria
Silvia Velasco

Stanley Center
Broad Institute, Harvard University, USA

11:00 – 11:05 EDT

Overview- Modeling Development and Disease: Neural
Marianne E. Bronner, PhD – California Institute of Technology
11:05 – 11:20 EDT

RECONSTRUCTION OF THE HUMAN BLOOD-BRAIN BARRIER USING INDUCED PLURIPOTENT STEM CELLS TO MODEL CEREBRAL AMYLOID ANGIOPATHY
Li-Huei Tsai, PhD – Massachusetts Institute for Technology; Joel Blanchard – Massachusetts Institute of Technology
11:25 – 11:33 EDT

STEM CELL-DERIVED NEURONS PROVIDE THE MISSING LINK BETWEEN ALS PATHOLOGY AND MOTOR NEUROPATHY
Joseph Klim – Harvard University
11:35 – 11:43 EDT

NETWORK-BASED PREDICTION AND VALIDATION THROUGH SYSTEMATIC PROFILING OF CAUSAL SCHIZOPHRENIA GENES IN HUMAN CORTICAL NEURONS.
Maria Kousi – Massachusetts Institute of Technology (MIT)
11:45 – 11:53 EDT

BRAIN ORGANOIDS REPRODUCIBLY GENERATE THE CELLULAR DIVERSITY OF THE HUMAN CEREBRAL CORTEX
Silvia Velasco – Broad Institute, Harvard University
11:55 – 12:03 EDT

INTERSPECIES CHIMERIC FRAGILE X SYNDROME MODEL REVEALS FMR1-DEPENDENT NEURONAL PHENOTYPES
Marine A. Krzisch – Whitehead Institute for Biomedical Research
12:05 – 12:13 EDT

ALZHEIMER PATIENT-DERIVED INDUCED NEURONS REVEAL A WARBURG-LIKE METABOLIC SWITCH
Larissa Traxler – University of Innsbruck
12:15 – 12:30 EDT

BASIC AND TRANSLATIONAL DISEASE MODELING WITH PATIENT IPSC-DERIVED NEURAL CELLS
Haruhisa Inoue, MD, PhD – CiRA, Kyoto University