Category: Clinical Sciences/Health Conditions
To provide a comprehensive and thorough review of the existing literature with regards to the identification and management of neuropathic pain in the pediatric population. Specifically, to provide an updated and concise analysis of the current pharmacological, interventional, and alternative modalities of treatment of neuropathic pain in the pediatric population.
An exhaustive literature review of the relevant published works was completed. Our literature review was conducted using PubMed, OVID, and Google Scholar databases. Over 400 articles were surveyed (after exclusion criteria applied), which included, but was not limited to various case reports, randomized controlled trials, systematic reviews, retrospective cohort studies, and case series. Searches were conducted using the following key words: ‘Pediatric,’ ‘Neuropathic Pain,’ 'Neuralgia,' 'Therapy, 'Diet Therapy,' 'Drug Therapy,' 'Rehabilitation'. Articles were excluded based on pre-determined criteria (i.e., written in English, availability of full text, age 0-18, date of article publication, level of evidence rating). General and overall recommendations for treatment of neuropathic pain in the pediatric population were generated and organized within our review based on overall level of evidence rating of the treatment modalities studied in each of the surveyed articles.
Through conduction of this literature review we were able to devise an up to date collection of guidelines regarding identification, management, and treatment of neuropathic pain in the pediatric population. Treatment and management modalities included pharmacologic interventions (i.e., Gabapentin, Lyrica, Lidocaine, Tricyclic Anti-depressants), surgical and invasive interventions (i.e., Nerve block, spinal cord stimulator), physical modalities (i.e., exercise, physical therapy) as well as other miscellaneous treatments (i.e., psychological therapy).
Through our study, current pediatric neuropathic pain treatments as well as management and identification strategies were identified and outlined in detail, and an up to date collection of guidelines and recommendations were provided for the treatment of neuropathic pain in the pediatric population.
Faheem Mahomed– Resident Physician, University of Texas Health - San Antonio
Caroline Brennick– Resident Physician, University of Texas Health - San Antonio
Kendall Hulk– Resident Physician, University of Texas Health - San Antonio
Allan Lara– Resident Physician, University of Texas Health - San Antonio
Nicholas Fleming– Assistant Professor, Department of Physical Medicine and Rehabilitation, Baylor College of Medicine