Category: Clinical Sciences/Health Conditions
The capacity of articular cartilage is limited to heal due to low mitotic potential of chondrocyte in vivo. Thus defect in the Joint cartilage progress to osteoarthritis (OA). To address this limitation, the use of Platelet Rich Plasma (PRP) was investigated. The objective was to find out the efficacy of PRP in mild to moderate osteoarthritis (OA) of knee joint.
It is a prospective experimental study. We recruited thirty patients of osteoarthritis knee joints treated by PRP from 1st June to 31st December, 2018.. According to radiological grading of knee OA, 12(40%) were in grade-1, 11(36.66%) were in grade-2, 7(23.33%) were in grade-3. Each patient took PRP at 1 month interval for 3 months. With all aseptic precautions, 10cc PRP was injected by Ultrasound (US) guided into knee joint followed by planned rehabilitation program at 2 weeks and 3 follow up was taken at 4 weeks, 8 weeks & 12 weeks. The mean Platelets count were 200±45.58 (mean±SD) K/µgm.
Approach to PRP into mild to moderate Knee OA can reduce disability and prevent the early progression of osteoarthritis. Though the outcome is good in this small study, large scale study is recommended.
mohammad moniruzzaman– Associate Professsor, Dhaka Medical College