Objectives: To demonstrate the effectiveness of tDCS associated with rehabilitation in maintaining gait improvements and balance in patients with Parkinson's disease.
Design: We enrolled 16 patients (10 males, 6 females; age 60±7.2) with PD and 2.5-4 grade of Hoen & Yahr scale. The patients were randomly assigned to case group (A) undergone conventional rehabilitation therapy combined with tDCS (n=8) and control group (B) undergone rehabilitation therapy alone. 10 sessions of tDCS with a 2mA intensity, (left dorsolateral prefrontal cortex, LDLPFC and primary motor cortex, M1) were applied. Fall risk index using computerized balance board, gait parameters using sensorized treadmill and Time,up&go (TUG) using inertial sensor were used to evaluation. At beginning of the treatment (T0), at the end (T1) and after 1 month (T2) the patients were examined.
Results: In step length from 46.5(7.3) at T0 to 54(7.9) at T1, in TUG test from 13(4.6) at T0 to 10(3.1) at T1, in Fall Risk Index from 1.7(0.2) to 1.1(0.3), significant improvements were reported in both groups(p< .05). But at T2 these results were maintained (p< .05) only in group A compared to group B.
Conclusions: The sinergy of the tDCS and rehabilitative treatment, doesn’t makes the latter more effective, but more lasting. This demonstrated thanks to an instrumental analysis that becomes essential.
Nicola Marotta– PRM Resident / MD, Università "Magna Graecia" di Catanzaro
Andrea Demeco– PRM resident, Università "Magna Græcia" di Catanzaro
Angelo Indino– prm resident, Università "Magna Græcia" di Catanzaro
Gerardo de Scorpio– prm resident, Università "Magna Græcia" di Catanzaro
Roberto Bianchito– prm resident, Università "Magna Græcia" di Catanzaro
Cinzia Marinaro– PRM resident, Università "Magna Græcia" di Catanzaro
Ilaria Pino– PRM resident, Università "Magna Græcia" di Catanzaro
Antonio Ammendolia– PRM residency program director, Università "Magna Græcia" di Catanzaro