Objectives: To evaluate the effect of an exercise program on the morphological and functional echocardiographic variables, evaluate the quality of life of patients after ischemic stroke.
Design: A longitudinal, randomized clinical trial consisting of patients with clinically stable chronic ischemic stroke is being performed. Patients are being randomized into two groups: Control Group (CG): physical therapy intervention according to the National Institute for Health and Care Excellence protocol; and Intervention Group (IG): cardiovascular rehabilitation on a treadmill programmed at speed and inclination compatible with individual capacity for 45 minutes, three times a week for 16 weeks. Patients in both groups are undergoing transthoracic echocardiography and quality of life assessment (EuroQol) at the beginning and end of the protocol. Comparisons between groups were performed by Student's t-test, and between the moments, before and after intervention, were made by paired t-test. Significance level: p< 0.05. To date, the participations in the study of 17 patients (CG=7 and IG=10) were completed and analyzed and the participation of other patients is ongoing.
Results: There was a significant improvement in morphofunctional echocardiographic variables: left ventricular systolic diameter (LVSD, p=0.02), left ventricular mass (LVM, p< 0.01), LVM index (LVMI, p< 0.01), left atrium diameter (LA, p< 0.01); ejection fraction (EF, p< 0.01), systolic excursion velocity of the mitral annulus to the tissue Doppler (Wave S, p=0.04); left atrial volume index (LAVI, p < 0.01) and E/e' ratio (p=0.02) in the intervention group patients when compared to the control group at the end of the research protocol. There was an improvement in GI compared to CG in the pain and discomfort domain of the EUROQUOL questionnaire (p=0.02) at the end of the protocol.
Improvement of morphofunctional echocardiographic parameters and pain after the cardiovascular rehabilitation program suggests a favorable impact on cardiac function and quality of life after stroke.
Josiela C. S. Rodrigues– Physioterapist, HCFMB- UNESP
Gustavo Luvizutto– Professor, Federal University of Triangulo Mineiro
Tais Silva– Physiotherapist, University Estadual Paulista Júlio de Mesquita Filho, São Paulo, Brazil
Robson Prudente– Physiotherapist, FMB - UNESP
Rafael D. M. Costa– Physiotherapist, FMB - UNESP
Fernanda winckler– Biologist, FMB - UNESP
Juli T. Souza– Nutricionist, FMB - UNESP
Estefânia A. Franco– Nurse, FMB - UNESP
Caroline F.S.M. Silveira– Doctor, FMB - UNESP
Tainá F. Valadão– Physical Education teacher, FMB - UNESP
Daniele A. Rossi– Doctor, FMB - UNESP
Leticia C. Antunes– Physiotherapist, FMB - UNESP
Gabriel Pinheiro Modolo– Physician, Hospital das Clínicas da Faculdade de Medicina de Botucatu
Luis Martin– Doctor, FMB - UNESP
Rodrigo Bazan– Doctor, FMB - UNESP
Silmeia G. Z. Bazan– Doctor, FMB - UNESP