The purpose of this work is to describe a standard preparation method and clinical outcomes using the Angel concentration system (Arthrex; Naples, FL, USA) for knee OA.
A review of the electronic medical record was performed on 134 cases of patients who underwent PRP injections for knee OA. Ninety knees (65 patients) met criteria for inclusion. All patients had whole blood processed at 0% hematocrit using the Angel concentration system (104cc whole blood for unilateral OA, 156cc whole blood for bilateral OA). International knee documentation committee (IKDC) subjective scores completed at baseline and 3 months were collected and analyzed.
Overall, IKDC score improved from 42.3 ± 14.1 pre-injection to 59.7 ± 17.5 at 3 months post-injection (p < 0.001). Of the 90 knees injected with PRP, 57% met criteria for a positive response at 3 months with an average final IKDC score of 66.5 ± 15.0 (Δ 24.7±10.9). Increased patient age (p = 0.008) and body mass index (p = 0.008) were associated with lower three month subjective IKDC scores.
Michael Baria– Assistant Professor, Ohio State University Wexner Medical Center
robert Magnussen– Associate Professor, Department of Orthopedics, The Ohio State University Sports Medicine
Melissa Lau– Resident, The Ohio State University Sports Medicine
meghan Miller– Data analyst, Orthobiologics Program, The Ohio State University Sports Medicine
William Vasileff– Assistant Professor, Department of Orthopedics, The Ohio State University Sports Medicine
James Borchers– Professor, Deparment of Family Medicine, The Ohio State University Sports Medicine