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LBS01: Late Breaking: Cancer Biology and Biomarkers
LBS01 - LBS01: Late Breaking: Cancer Biology and Biomarkers
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LBS01.01 - Nasopharyngeal Carcinoma Exosomes Modify the Metabolism Status of Human Dendritic Cells and Favour their Recruitment through the CCL20 Chemokine
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LBS01.02 - Cytotoxic T Lymphocyte EV that Prevents Tumor Metastasis by Collapse of Tumoral Mesenchymal Stroma is classified into Exosome, but not Microvesicle or Apoptotic Body.
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LBS01.03 - CLIC4 is essential for breast cancer metastatic competence and predicts disease outcome
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LBS01.04 - The application of flow cytometry in an EV-based liquid biopsy for the detection of Cancer Multidrug Resistance in Myeloma
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LBS01.05 - Photodynamic Therapy using a New Folate-targeted Photosensitizer on Peritoneal Ovarian Cancer Cells Induces the Release of Extra-cellular Vesicules with Immunoactivating Properties
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LBS01.06 - Metabolomic profiling of serum and exosomes isolated from head and neck cancer patients after radiotherapy
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LBS01.07 - Proteomic profiling of small extracellular vesicles secreted by human pancreatic cancer cells implicated in cellular transformation
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LBS01.08 - Proteomic profile of tumor-derived exosomes in plasma of melanoma patients
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LBS01.09 - Isolation and characterization of prostate-derived extracellular vesicles as a liquid biopsy strategy in cancer diagnosis
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LBS01.10 - Paving the way for implementing a feasible and reliable technique for assessing urinary extracellular vesicles as biomarkers for bladder cancer in clinical practice
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LBS01.11 - The role of small extracellular vesicles secreted by cells with extra centrosomes in PDAC microenvironment remodelling
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LBS01.12 - Exosomal Carboxypeptidase E confers and CPE-shRNA loaded exosomes inhibit growth and invasion of hepatocellular carcinoma cells.
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LBS01.13 - Stress hormones promote prostate cancer aggressiveness through modulation of mir-628-5p expression and exosome release
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LBS02: Late Breaking: New Technologies and Methods
LBS02 - LBS02: Late Breaking: New Technologies and Methods
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LBS02.04 - Single Extracellular Vesicle Trapping by Aptamer-Au Nanoparticle Mediated Au Superlattices
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LBS02.05 - Edit The use of a DLS-based clinical platelet instrument beyond the blood transfusion laboratory
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LBS02.06 - Secreted protein of MSC: Adipose vs Umbilical Cord Tissue
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LBS02.07 - Development of scalable monolith chromatography processes for the purification of exosomes from a clinically relevant stem cell product
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LBS02.08 - Using degron-tagged reporters to specifically label and track extracellular vesicles in vivo
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LBS02.09 - Heterogeneity and batch variation of HEK293 extracellular vesicles
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LBS03: Late Breaking: Specific Cell Derived EVs
LBS03 - LBS03: Late Breaking: Specific Cell Derived EVs
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LBS03.2 - Blunted postprandial suppression of phosphoenolpyruvate carboxykinase in kidney-derived urinary exosomes in early insulin resistance in humans
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LBS03.3 - Differential characterization of extracellular vesicles in neuroprotective human platelet lysate preparations
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LBS03.4 - GMP compatible angiogenic exosome processing toward therapeutic for treating stroke
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LBS03.5 - Neuronal-origin plasma EVs provide biomarkers for Parkinson’s Disease
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LBS03.7 - Urinary extracellular vesicles as biomarkers of kidney allograft injury: optimization of isolation protocol and characterization
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LBS03.10 - Astrocyte-derived extracellular vesicles regulate dendritic spine formation and neuronal network connectivity
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LBS03.11 - Enhancement of immunomodulatory functions of MSC-derived extracellular vesicles through modification of up-stream parameters
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LBS03.12 - Donor Source Affects Potency of Mesenchymal Stem Cell-derived Extracellular Vesicles
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LBS03.13 - Analysis of extracellular vesicle populations from malaria-infected erythrocytes by field-flow fractionation reveal distinct sub-sets
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LBS03.14 - Evidences on microalgal extracellular vesicles: a morphological assessment
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PF01: EVS in Metabolism and Metabolic Disease
PF01 - PF01: EVS in Metabolism and Metabolic Disease
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PF01.02 - Release of larger extracellular vesicles post-acute exercise is associated with the exercise responder phenotype in youth living with obesity
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PF01.03 - Using dual-fluorescent reporter mice to track tissue-specific extracellular vesicles
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PF01.04 - Endothelial CD36 delivery of FA loaded extracellular vesicles is critical for thermogenesis.
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PF01.05 - Nanovesicles from orange juice restore the intestinal functions altered during diet-induced obesity in mice.
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PF01.06 - Association, structure, and function of fibronectin in extracellular vesicles from hepatocytes
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PF01.07 - Elevated glucose increases soluble and aggregated forms of human islet amyloid polypeptide in islet-derived extracellular vesicles – Implications in type 2 diabetes and islet transplantation
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PF01.08 - Contraction, but not glycolysis, regulates the size of skeletal muscle EVs secreted ex vivo.
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PF02: EVs as Delivery Vehicles
PF02 - PF02: EVs as Delivery Vehicles
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PF02.03 - Cell-penetrating sC18 peptide-modified extracellular vesicles for intracellular delivery
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PF02.05 - Natural or Synthetic: A Comparison of the Efficiency of Extracellular Vesicles vs Synthetic Carriers for RNA Delivery
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PF02.09 - The Role of Circulating Extracellular Vesicles in Patients with Chronic Chagas Disease
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PF02.10 - Extracellular Vesicles - a Trojan horse for therapeutic agent delivery
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PF02.11 - Hybrid extracellular vesicles - biomimetic tool for drug delivery to repair endothelial cell dysfunction
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PF03: EVs of Non-mammalian Organisms
PF03 - PF03: EVs of Non-mammalian Organisms
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PF03.01 - Investigating the effects of oxidative stress on extracellular vesicle function and cargo loading
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PF03.02 - Mutant p53 governs tumor microenvironment dynamics via exosomes and outer membrane vesicles
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PF03.03 - S. oneidensis vesicle loading is driven by BAR domain protein and outer membrane cytochrome interplay
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PF03.04 - Enhancement of intestinal IgA production via Peyer’s patch dendritic cells by membrane vesicles derived from lactic acid bacteria (Lactobacillus sakei)
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PF03.05 - Identification and evaluation of potential new biomarkers of trematode infections in Extracellular Vesicles
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PF03.06 - Life stage-specific glycosylation of schistosome-derived extracellular vesicles
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PF03.07 - Isolation and characterization of Extracellular Vesicles from phloem sap reveals their possible role in defense against phloem-feeding insects
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PF03.08 - Extracellular vesicles from nematode species Heligmosomoides bakeri and Trichuris muris contain distinct small RNAs that could enable niche specificity in the host
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PF04: EV Nucleic Acid Biomarkers
PF04 - PF04: EV Nucleic Acid Biomarkers
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PF04.02 - Circulating non-coding RNA biomarkers of cancers in extracellular vesicles and serum
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PF04.05 - Identification of novel EV-associated miRNAs as toxic biomarkers in mouse
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PF04.07 - Cancer-specific genomic alterations in plasma large EVs from patients with advanced cancer
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PF04.08 - Detection of EGFR mutations in exosomal RNA and protein mirrors disease status in metastatic lung cancer patients
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PF04.09 - Identification of plasma-derived, EV-based biomarkers for glioblastoma
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PF04.12 - Identification of a saliva exosomal RNA signature for Sjogren’s syndrome
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PF04.14 - Endometrial fluid derived EVs as low invasive diagnostic biomarkers of implantative endometrium
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PF04.16 - Small RNA cargo of EVs is affected by hormone treatment in prostate cancer
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PF05: EV Protein Biomarkers
PF05 - PF05: EV Protein Biomarkers
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PF05.02 - Detection of PD-L1 in circulating extracellular vesicles
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PF05.03 - Differences in extracellular vesicle protein cargo is dependent on head and neck squamous cell carcinoma cell of origin
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PF05.04 - Validation of antibodies on western blot for extracellular vesicles from biological human samples and cancer cell conditioned media
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PF05.08 - Proteomic study of mesenchymal stem cells derived exosomes modified using miR.
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PF05.11 - A Novel Extracellular Vesicle Isolation Method Used to Discover Urine Liver Disease Biomarkers
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PF05.12 - Evaluation of plasma extracellular vesicles in Rheumatoid Arthritis and Systemic Lupus Erythematosus
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PF05.13 - Using extracellular vesicles as a template for autoimmune diagnostic screening
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PF05.14 - Circadian variation of extracellular vesicles secreted in urine: Analysis of time point collection and normalization strategy.
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PF05.16 - Porcine body fluids differ in small extracellular vesicle counts: comparison of blood plasma, seminal plasma and cerebrospinal fluid as vesicle sources for proteomic analyses
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PF05.18 - Identification of potential pancreatic cancer therapeutic targets in the cargo of extracellular vesicles released by human macrophages
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PF06: EVs in Reproduction and Pregnancy
PF06 - PF06: EVs in Reproduction and Pregnancy
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PF06.02 - In vivo derived bovine blastocyst secrete different population of extracellular vesicles compared to vitro produced counterparts
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PF06.03 - Extracellular vesicles as messengers in early embryo-maternal communication
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PF06.04 - Arrdc4-dependent extracellular vesicle biogenesis is required for sperm maturation
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PF06.05 - Maternal EV-derived myomiRs are associated with the development of large-for-gestational age babies in pregnancies complicated by gestational diabetes
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PF06.06 - A new type of nanovesicles in seminal plasma: the myelinosomes
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PF07: EVs in Kidney, Urinary Tract, and Related Diseases
PF07 - PF07: EVs in Kidney, Urinary Tract, and Related Diseases
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PF07.01 - Tuberous sclerosis complex axis controls extracellular vesicles production and protein content
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PF07.02 - Extracellular vesicles derived from human amniotic fluid stem cells: characterization and therapeutic effect in a model of chronic kidney disease
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PF07.03 - A millifluidic in vitro model of glomerular filtration to test the regenerative effect of extracellular vesicles under dynamic conditions
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PF07.04 - Extracellular vesicles from kidney cancer tissue and comparison of two quantitative methods
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PF07.05 - Tetraspanins on Serum derived-EVs Enable Detection of Renal Cell Carcinoma
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PF07.06 - Extracellular Vesicles as a Source of Cancer Biomarkers in the Urine of Urothelial Carcinoma Patients: characterization of a two-step protocol for the isolation of urine-derived EVs
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PF08: EVs in Cancer Pathogenesis
PF08 - PF08: EVs in Cancer Pathogenesis
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PF08.01 - Extracellular vesicles are involved in the expansion of the mesenchymal signature in glioblastoma tumours
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PF08.02 - Inhibition of extracellular vesicle release in triple negative breast cancer
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PF08.05 - Extracellular vesicles from highly metastatic lung cancer cells induce barrier impairment, permeability, and epithelial-to-mesenchymal plasticity in a 16-day mature bronchial epithelium
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PF08.06 - Grp78 plays a crucial role in the extracellular vesicle-promoted radioresistance of irradiated head and neck cancer cells
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PF08.09 - 3D modeling of EV release in progressing prostate cancer
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PF08.10 - Multiplex analysis of renal cell carcinoma cell extracellular vesicles to identify potential clinically relevant markers
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PF08.11 - Low molecular weight protein tyrosine phosphatase (LMWPTP) carried by colorectal cancer cells-derived extracellular vesicles as a player in tumor-educated human fibroblast
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PF08.15 - Exosomal miR-181a Inhibition by Vincristine and Prednisone in Pediatric Acute Lymphoblastic Leukemia.
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PF08.16 - Secreted extracellular vesicles from renal cell carcinoma cells
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PF08.17 - Tumor cell-derived small extracellular vesicles modulate macrophage immunosuppressive phenotype associated with PD-L1 expression
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PF08.18 - Exosomes synthesizing HER2 miRNA and engineered to adhere to HER2 on tumor cells surface exhibit enhanced anti-tumor activity
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PF08.19 - Systematic Characterization of Ovarian Cancer-derived Exosomes Unveil miRNAs Interfering with CD8+ T Cell Activation
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PF08.20 - Irradiation of breast cancer cells alters the quality of DNA cargo in the exosomes that they produce
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PF08.21 - IRE1 inhibition modulates immune phenotype of triple negative breast cancer cells and cancer-derived extracellular vesicles
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PF09: EVs in Cancer Pathogenesis
PF09 - PF09: EVs in Blood Disorders
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PF09.01 - Comparison of three isolation protocols to search extracellular vesicles signature in sickle cell disease patients
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PF09.02 - Extracellular vesicles from patients with sickle cell disease disrupt gap junctions
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PF09.03 - The effects of platelet concentrate storage time on extracellular vesicle interactions associated with fibrin clot formation in-vitro
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PF09.04 - Characterization of miRNA from serum derived exosomes in a mouse tibia fracture model of Complex Regional Pain Syndrome
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PF09.05 - Extracellular Vesicle-based liquid biopsy in Acute Myeloid Leukaemia: a reliable source of residual disease biomarkers?
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PF10: Cell-EV Interaction, Uptake, and Fusion
PF10 - PF10: Cell-EV Interaction, Uptake, and Fusion
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PF10.01 - Profiling mRNAs of parental prostate cancer cells with different phenotypes and their daughter extracellular vesicles using the NanoString low RNA input nCounter assay
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PF10.05 - Cancer cell-derived EVs containing alphaV beta6 Integrin regulate CD163, IL-6 and IL-10 levels in peripheral blood mononuclear cells
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PF10.07 - T Cell Activation by Allogeneic EVs and Allogeneic MHC Cross-Dressed Cells in vitro and in vivo
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PF10.09 - Antifungal antibiotic activity of outer membrane vesicles from adherent Lysobacter enzymogenes C3 against therapeutic and biocontrol targets.
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PF10.10 - Elucidating the cellular uptake and tissue distribution mechanism of cell derived vesicles, a novel therapeutic carrier
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PF10.11 - Myofibroblasts-derived microvesicles increase dermal fibroblasts collagen production through PLGF-1
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PF10.12 - Structural Insights on Fusion Mechanisms of Extracellular Vesicles with Model Plasma Membranes
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PF11: EVs as Intrinsic Medicines
PF11 - PF11: EVs as Intrinsic Medicines
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PF11.02 - Platelet Enhanced Plasma: A Novel Extracellular Vesicle Enriched Resuscitation Fluid?
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PF11.05 - Therapeutic Effect of Exosomes in Mice Model of Autism
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PF11.06 - miRNAs enriched in extracellular vesicles isolated from plasma- and serum-based autologous blood-derived products for osteoarthritis therapy
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PF11.08 - Protective role of shiitake mushroom-derived exosome-like nanoparticles in D-galactosamine and lipopolysaccharide-induced acute liver injury in mice
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PF11.10 - Approaches to Assess Clinically Available Exosomes' Quality and Safety
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PF11.11 - Engineering Pro-Healing EV Cargo Using a Closed-System Bioreactor.
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PF11.12 - Comprehensive analysis of methods and outcome reporting in preclinical animal studies of mesenchymal stem cell derived extracellular vesicles: A systematic review
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PF11.14 - MSC-Exosomes as Next Generation Therapeutics for Atopic Dermatitis
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PF11.15 - Cell derived vesicles: Unraveling the science of novel vesicles with therapeutic promises
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PF11.16 - Antifibrotic properties of extracellular vesicles derived from human induced pluripotent stem cells
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PF11.17 - Induced pluripotent stem cells- derived extracellular vesicles ameliorates D-galactosamine and lipopolysaccharide induced acute liver failure
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PF11.18 - MSC-derived extracellular vesicles promote human cartilage regeneration by control of autophagy
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PF11.19 - Large-scale preparations of small extracellular vesicles from conditioned media of mesenchymal stromal cells modulate therapeutic impacts on a newly established Graft-versus-Host-Disease model in batch dependent manners
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PF11.20 - Milk Extracellular Vesicles Can Repair Malnutrition-induced Gut Barrier Dysfunction
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PF11.21 - The impact of spheroids culture on mesenchymal stem cells and EV production
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PF11.22 - Outer Membrane Vesicles from Photobacterium damselae subsp. piscicida: characterization and antigenic potential
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PF12: Advances in Characterization of EV-associated Molecules: Omics
PF12 - PF12: Advances in Characterization of EV-associated Molecules: Omics
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PF12.01 - Comparison of Extracellular Vesicle Isolation Methods from Small Volumes of Urine for Radiation Metabolomics Analysis.
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PF12.02 - MALDI-TOF MS fingerprinting of potential esophageal cancer biomarkers in exosomes isolated by LEAPS
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PF12.03 - Fraction-based Proteomic profiling of serum extracellular vesicles derived from cervical cancer patients
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PF12.05 - Isolation methods of exosomes optimized for biomarker screening based on proteomic analysis using 2-D gel electrophoresis
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PF12.07 - An extracellular small RNA-seq data processing pipeline optimized for high-performance computing
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PF12.09 - Characterization of extracellular vesicles (EVs) derived from Peripheral Blood Mononuclear Cells (PBMCs) of Inflammatory Bowel Disease (IBD) patients
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PF12.10 - Proteomic analysis of exosomes isolated using precipitation and column-based approaches
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PF13: Separation and Concentration
PF13 - PF13: Separation and Concentration
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PF13.02 - From total plasma EVs to immuno-captured neuronal EVs - yield, purity and enrichment
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PF13.03 - Characterisation of breath exosomes: towards non-invasive diagnosis
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PF13.04 - Ligand-based Exosome Affinity Purification (LEAP) is a rapid and reproducible method for the enrichment of functional EVs
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PF13.05 - A Novel but Simple Method to Obtain Purified Exosomes by One-Step Ultracentrifugation
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PF13.07 - A straightforward device to extract apoplastic fluid from succulent fruits for higher purity of extracellular vesicles
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PF13.08 - Method to Simultaneously Capture Multiple Classes of Intact Extracellular RNA Carriers Including Extracellular Vesicles and Lipoprotein Particles
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PF13.09 - Optimizing the isolation of placental mesenchymal stromal cell-derived extracellular vesicles in a 3D bioreactor system
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PF13.10 - A Novel Method For Isolating Extracellular Vesicles From Cell Culture Media and Plasma Using Polyethylenimine
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PF13.11 - Assessment of Various Extracellular Vesicle Isolation Methods Through Chemical Analysis with Surface-Enhanced Raman Spectroscopy
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PF13.12 - Bioreactors: lessons to develop an Extracellular Vesicle factory
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PF13.13 - Rapid and efficient isolation of extracellular vesicles by Phosphate−DNA−Cholesterol functionalized defected Metal Organic Framework
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PF14: EVs as Delivery Vehicles
PF14 - PF14: EVs as Delivery Vehicles
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PF14.02 - Site-specific integration enables rapid cell engineering for the development of precision extracellular vesicle therapeutics
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PF14.03 - Transport of Outer Membrane Vesicles as a Model Therapeutic Delivery System in Pathogenic and Commensal Bacteria
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PF14.04 - Utilizing a Gaucher’s Disease Cell Line for the Evaluation of a Novel Exosome-Based Replacement Therapy
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PF14.06 - ThRxosomes: A Novel Exosomes Based Theranostic for Lung Cancer
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PF14.08 - Exosome-modified nanoparticles as an alternative delivery system for small RNAs in cancer therapy
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PF14.09 - Microglial Extracellular Vesicles as Therapeutic Vector for Neuroinflammation
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PF14.10 - Targeting IL-3Rα on tumor-derived endothelial cells blunts metastatic spread of triple negative breast cancer via extracellular vesicle reprogramming
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PF15: EVs in Cancer Metasis and Tumor Angiogenesis
PF15 - PF15: Evs in Cancer Metasis and Tumor Angiogenesis
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PF15.01 - Statins decrease the implantation and invasion of high-grade serous ovarian cancer cells induced by exosomes by altering its composition and its cell uptake and the endocytic traffic at the metastatic niche.
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PF15.02 - Label-free optical imaging and characterization of cancer-associated extracellular vesicles in tissues
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PF15.03 - Novel potential anticancer therapies based on interference with nuclear entry of cancer cell-derived extracellular vesicle components in recipient cells
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PF15.05 - Educated osteoblasts regulate breast cancer proliferation via small extracellular vesicles
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PF15.06 - Phosphorylation of Tyrosine 23 in Annexin A2 is Essential for its Association with Exosomes and for Imparting Invasive and Proliferative Capacity to other Cells
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PF15.07 - A novel method for epithelial-derived extracellular vesicle isolation and enrichment in patients with advanced prostate cancer
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PF15.11 - Exosomes drive medulloblastoma metastasis in a MMP2 and EMMPRIN dependent manner
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PF15.12 - Anti-migratory effect of Nm23-H1 via exosomes
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PF16: EVs in Tissue Injury and Repair
PF16 - PF16: EVs in Tissue Injury and Repair
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PF16.01 - Moderate exercise has beneficial effects on mouse ischemic stroke by enhancing the functions of circulating endothelial progenitor cell-derived exosomes via activation of the miR-126/BDNF/PI3k pathway
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PF16.02 - Syndecan-1 Regulates Alveolar Type 2 Epithelial Cell Senescence Mediating Through Extracellular Vesicles During Lung Fibroproliferation
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PF16.03 - Immortalized Cardiosphere-Derived Cell EV-associated piRNA, imEV-Pi, protects against ischemic injury in the heart
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PF16.05 - Enhancement of extracellular vesicles from umbilical stem cell in hair follicle regeneration
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PF16.06 - Mechanisms of host resistance to plasma membrane damage induced by pneumolysin attack
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PF17: Oral with Poster Session 2: Cancer and Technology
PF17.01=OP2.01 - Development of scalable processes to produce therapeutic mesenchymal stromal cell-derived extracellular vesicles and their characterization
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PF17.03=OP2.03 - Concentration measurements by nanoparticle tracking analysis strongly depend on the particle refractive index
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PF17.04=OP2.04 - Evaluation of three different isolation methods for small extracellular vesicles from human plasma in prostate cancer diagnosis
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PF17.05=OP2.05 - Multiplexed surface protein profiling of tumor-derived extracellular vesicles by an electrokinetic sensor
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PF17.07=OP2.07 - Optimized immunocapture methods for the direct detection of EV tumour associated proteins in biological fluids: playing around with biophysics
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PF17.08=OP2.08 - Normalized extravesicular protein expression profiles on antibody microarrays reveal protein associations in EVs of organotropic and metastatic breast cancer cell lines
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PF17.09=OP2.09 - Heparan sulphate proteoglycans are required for EV-mediated delivery of multiple growth factors
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PF17.12=OP2.12 - Robust exosomal biomarker panel discovery in ovarian cancer using machine learning approaches and studying miRNA & miRNA-target interactions
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PF17 - Oral with Poster Session 2: Cancer and Technology
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PS01: EVs in Infectious Diseases and Vaccines
PS01 - PS01: EVs in Infectious Diseases and Vaccines
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PS01.01 - Ethanol and HIV-induced exosome from hepatocytes activate hepatic stellate cells
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PS01.02 - Antimicrobial peptide LL-37 induces neutrophil-derived extracellular vesicles with antibacterial potential and protects murine sepsis
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PS01.03 - Identification of miRNA profiles of serum exosomes in active tuberculosis
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PS01.04 - The new therapy to treatment experimental Acute Chagas Disease
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PS01.09 - Characterization of outer membrane vesicle-carried proteins as pathogenicity factors from Acinetobacter baumannii
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PS01.10 - Talaromyces marneffei yeasts-derived Extracellular Vesicles Mediate Inflammatory Response and Modulate Macrophage Functions
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PS01.11 - Plasma-derived extracellular vesicles as potential biomarkers in chronic Chagas disease patients
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PS01.12 - Eukaryotic extracellular vesicles and prokaryotes – a different perspective
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PS01.13 - Hydrogen sulfide (H2S) derived extracellular vesicles: a potential protective role in response to respiratory syncytial virus (RSV) infection
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PS01.14 - Effects of extracellular vesicle-mediated transmission on Reoviridae infection
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PS01.15 - Multiparameter flow cytometry analysis of the human spleen and its interaction with plasma-derived EVs from Plasmodium vivax patients
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PS02: EVs in Cancer Metastasis and Tumor Angiogenesis
PS02 - PS02: EVs in Cancer Metastasis and Tumor Angiogenesis
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PS02.01 - Activating protein-1 and extracellular vesicles in cancer metastatic behavior phenocopying
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PS02.02 - Neuroblastoma-secreted exosomes carrying miR‐375 promote osteogenic differentiation of bone marrow mesenchymal stromal cells
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PS02.03 - Effects of Small-Extracellular Vesicles on cell biomechanical properties in metastatic breast cancer
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PS02.04 - Stratification of angiogenic or non-angiogenic lesions in colorectal cancer liver metastases patients using extracellular vesicle miRNA
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PS02.06 - The role of extracellular vesicles from cancer cells in bone metastasis
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PS02.08 - Increased expression of chemokine receptor CXCR4 in non-invasive colorectal cancer cells after incorporation of platelet-derived extracellular vesicles.
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PS02.10 - Changes of miRNA profile in extracellular vesicles released by colorectal cancer cells during early EMT
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PS02.11 - Extracellular vesicles from prostate cancer cells deliver microRNAs to promote osteogenesis
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PS02.12 - Proteomic Profiling of Retinoblastoma-Derived Exosomes reveals potential biomarkers of vitreous seeding
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PS02.14 - Activation of hepatic stellate cells by extracellular vesicles released by uveal melanoma cells
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PS02.15 - Exosome of cancer-associated fibroblast induce anti-cancer drug-resistance of NSCLC
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PS03: EVs in Intrinsic Medicines
PS03 - PS03: EVs in Intrinsic Medicines
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PS03.01 - Proteomic Analysis of Amniotic Fluid-Derived Exosome Cargo Reveals a Therapeutic Potential for Regenerative Therapies.
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PS03.03 - Generation of CAR-T and γδT Cell-derived Exosomes for Future Cell Free Immunotherapies
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PS03.04 - Characterization, composition, and biological properties of extracellular vesicles generated from human induced pluripotent stem cell-derived neural stem cells
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PS03.05 - Promise of neural stem cell-derived extracellular vesicles for combating age-associated cognitive and mood impairments
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PS03.08 - Chemically modified myocytes-derived EVs for the treatment of cardiac fibrosis.
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PS03.09 - Evaluation of Osteoinductive and Anti-Inflammatory Properties of Spine-Derived Exosomes
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PS03.10 - Administration of human Mesenchymal Stem Cell derived extracellular vesicles modulates the abnormal plasticity of newly born neurons and neuroinflammation in a rat model of status epilepticus
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PS03.11 - Intranasal administration of exosomes improves the symptoms in three mice model of Autism
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PS03.12 - Equine tendon injury treatment by EVs: an in vitro study
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PS03.13 - EV-enriched secretome fraction from GMP-compatible, scalable, human iPSC-derived cardiac progenitors improve heart function in chronic heart failure mice
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PS03.14 - Electrospun Collagen Coupled with Spine Bone Marrow-Derived Exosomes
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PS03.15 - Exosomes loaded with PTEN-Interfering RNA enables functional recovery in rats after complete spinal cord transection
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PS03.16 - A Novel Umbilical Cord Derived Wharton’s Jelly Formulation For Regenerative Medicine Applications
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PS03.17 - Improvement of immunosuppressive extracellular vesicles by HIF-1alpha overexpression and priming of parental mesenchymal stromal cells
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PS03.18 - Collagen sponge loaded with mesenchymal stem cell-derived small extracellular vesicles promote robust bone regeneration
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PS03.19 - Immunomodulatory Potential of Extracellular Vesicles Derived from Mesenchymal Stromal Cells
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PS03.20 - Extracellular Vesicles in Platelet-rich Plasma: Dependency on Sample Processing
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PS03.21 - Satellite Cell-Derived Extracellular Vesicles as a Therapeutic for Mitochondrial Dysfunction in Duchenne Muscular Dystrophy
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PS04: Advances in EV Quantification
PS04 - PS04: Advances in EV Quantification
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PS04.03 - Quantitation of extra-cellular vesicle surface markers with MESF liposomes
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PS04.05 - Measuring cholesterol as a high-throughput method for quantifying extracellular vesicles
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PS04.06 - Optimization of nanoparticle tracking analysis of extracellular vesicles isolated from plasma and bronchopulmonary lavage fluid of patients with non-small cell lung cancer
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PS04.08 - Introducing a universal fluorescence extracellular vesicle stain for NanoView Bioscience’s Exoviewer platform
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PS04.09 - Membrane labeling is essential for the identification and quantification of extracellular vesicles via FACS
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PS04.10 - Surface plasmon field-enhanced fluorescence spectroscopy (SPFS) system for quantitative and qualitative extracellular vesicles total evaluation without any sample pretreatment
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PS04.12 - Identification of a novel compound that inhibits small EV secretion and tumor progression by a sensitive ELISA screening.
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PS04.13 - Quantitative proteomics identifies proteins enriched in microvesicles and exosomes respectively
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PS05: EVs in the Central and Peripheral Nervous Systems
PS05 - PS05: EVs in the Central and Peripheral Nervous Systems
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PS05.01 - Vesicle secretion by ependymal cilia in brain ventricle
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PS05.02 - Mitochondrial vesicles in neurons
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PS05.03 - The role of small extracellular vesicles in chronic neuropathic pain
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PS05.06 - Large and small extracellular vesicles in ALS: friends or foes?
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PS05.08 - Combining high-resolution flow cytometry and surface marker analysis using an automated platform to study extracellular vesicle in cerebrospinal fluid
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PS05.09 - A distinct microRNA signature in plasma derived small extracellular vesicles of different neurodegenerative diseases
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PS05.12 - Role of exosomes in the development of dendritic filopodia, spines and synapses
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PS05.13 - Effects of apolipoprotein E genotype on protein and small RNA profiles of brain tissue-derived extracellular vesicles of Alzheimer’s disease patients
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PS05.14 - Efficient pathology spread by extracellular vesicles from human brain tissues in mouse brain and tissue cultured neurons: Transmission and propagation to GABAergic neurons
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PS05.15 - Isolation of extracellular vesicles from cerebrospinal fluid and characterization of their bioactive compounds to investigate multiple sclerosis pathogenesis
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PS05.16 - Differences in circulating number of extracellular vesicles between contact sport athletes with and without acute mTBI: a pilot study
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PS05.17 - Plasma-derived Extracellular Vesicles profiling as a biomarker for Parkinson’s Disease
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PS05.18 - Separation and characterization of extracellular vesicles from human cerebrospinal fluid
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PS06: EVs in Cardiovascular Diseases and Vascular Disorders
PS06 - PS06: EVs in Cardiovascular Diseases and Vascular Disorders
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PS06.01 - Release of extracellular vesicles from platelets requires platelet-platelet interaction
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PS06.04 - Age-dependent alteration in concentration and size distribution of extracellular vesicles in plasma of normotensive and hypertensive rats
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PS06.05 - microRNA profiling of circulating extracellular vesicles is involved with susceptibility to age-related diseases: relevance to cardiovascular signaling in aging process
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PS06.07 - Endothelial cell-derived extracellular vesicles induce a smooth muscle cell pro-inflammatory phenotype via HMGB1
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PS06.08 - Double value of Microvesicles in CABG: patency predictive capacity and tool for personalized antiplatelet therapy
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PS06.09 - Exosomes from engineered immortalized human heart cells improve ventricular function and attenuate fibrosis in mice with arrhythmogenic cardiomyopathy
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PS06.10 - Cardiac-derived Extracellular Vesicles Contribute to Communication between Heart and Brain in Chronic Heart Failure (CHF) and Target Nrf2/ARE Signaling
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PS06.11 - Ischemia impairs the ubiquitin-mediated secretion of Cx43 into extracellular vesicles
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PS06.12 - Cardioprotection mediated by calcium-ionophore induced extracellular vesicles
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PS07: EV Nucleic Acid Biomarkers
PS07 - PS07: EV Nucleic Acid Biomarkers
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PS07.01 - Extracellular-Vesicle microRNAs for detecting Pancreaticobiliary Cancers
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PS07.02 - Optimization of Urinary Extracellular mRNA Profiling during Pregnancy
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PS07.03 - IL-2 mutein-induced changes of exosomal miRNA cargo in a humanized mouse model
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PS07.05 - Identification of potential biomarkers in microglial specific exosomes isolated from prion-infected serum
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PS07.06 - Comparison of urinary extracellular vesicle isolation methods for transcriptomic biomarker research in diabetic kidney disease
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PS07.07 - cfDNA distribution in bioliquids: exosome-associated vs. free circulating form
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PS07.08 - Tracing extrachromosomal DNA inheritance patterns in glioblastoma using CRISPR
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PS07.09 - RNA signatures of mouse primary neurons, astrocytes and their small extracellular vesicles
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PS07.10 - Isolation and characterization of Extracellular vesicles (EVs) and EV RNA in human urine samples
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PS07.11 - Vn96-Isolated Plasma Extracellular Vesicles Improve Tumor Mutation Detection By Next-Generation Sequencing Compared To Cell-Free DNA and Correlate With Tissue Biopsy of NSCLC Patients
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PS07.12 - Novel markers for neuroendocrine prostate cancer
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PS07.13 - Exosomal mRNA in diagnosis strategy for hepatocellular carcinoma
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PS07.14 - Circulating extracellular vesicle signatures in small cell lung cancer
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PS08: Separation and Concentration
PS08 - PS08: Separation and Concentration
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PS08.03 - A fast and reliable in vitro cell culture system reveals that acidification of bovine milk extracellular vesicles impairs their functionality
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PS08.04 - Optimising methods for separation and characterisation of extracellular vesicles from skim milk and infant milk formula
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PS08.05 - A novel platform to isolate extracellular vesicles based on surface molecule expression uncovers functional differences between EV subpopulations
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PS08.06 - Preparation of agarose microspheres for high-efficient separation of extracellular vesicles
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PS08.10 - Immunomagnetic Sequential Ultrafiltration (iSUF) Platform for Enrichment and Purification of Extracellular Vesicles from Large and Small Volumes of Biofluid
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PS08.12 - Challenges in exosomes isolation from primary biological samples derived from multiple myeloma patients
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PS08.13 - A rigorous method for exosome isolation from post mortem eyes
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PS08.14 - Characterization of the extraction of extracellular vesicles using a lab-on-a-disc filtration system
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PS08.15 - Effects of Sample Processing on Isolation of Extracellular Vesicles from Blood Plasma by Centrifugation
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PS09: EVs in Cancer Pathogenesis
PS09 - PS09: EVs in Cancer Pathogenesis
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PS09.01 - Imaging extracellular vesicles arising from apoptotic tumour cells for cancer diagnosis and monitoring
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PS09.02 - Casting A Small Netrin: Functional roles of a Novel Surface Factor on Stroma-Derived Extracellular Vesicles in Pancreatic Cancer
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PS09.05 - Exosomes carry distinct miRNAs that drive medulloblastoma progression
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PS09.08 - Leukemic extracellular vesicles induce inflammatory regulators and suppress hematopoietic stem and progenitor cell function
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PS09.09 - SARI prevents glioblastoma multiforme progression by inhibiting the recruitment of myeloid-derived suppressor cells via SARI-bearing extracellular vesicles
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PS09.10 - Desmoglein 2 modulates extracellular vesicle microRNA content in squamous cell carcinoma
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PS09.11 - Cancer cells grown in 3D release distinct extracellular vesicles during tumor growth and invasion
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PS09.13 - Exploring Extracellular Vesicles release inhibition in Prostate Cancer
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PS09.14 - Patient-derived organoids represent a novel tool to study the effect of intra-tumoral heterogeneity on EV release in non-small cell lung cancer
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PS09.15 - Exosome Mediate Heart-Adipocyte Communication after Myocardial Ischemia/Reperfusion and Impairs Adipocyte Endocrine Function
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PS09.16 - Pancreatic cancer cell extracellular vesicles drastically alter the behavior of recipient normal pancreas cells
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PS09.17 - Plasma extracellular vesicles-miRNAs released by hypoxic cells are associated to pro-tumorigenic and immunosuppressive microenvironment in lung cancer
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PS09.18 - Exploration of EV-associated metastatic targets on melanoma cells
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PS09.20 - Analysing Extracellular Vesicles from Drug-Resistant and Drug-Sensitive Cancer Cells as potential Predictive Biomarkers in the Liquid Biopsy
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PS09.21 - Downregulation of Rab27a Expression Correlates with Replication Restriction of Oncolytic Herpes Virus in Tumor Cells
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PS09.22 - PS09: EVs in Cancer Pathogenesis
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PS10: Diverse EV Biomarkers
PS10 - PS10: Diverse EV Biomarkers
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PS10.04 - Raman spectral signature of urinary extracellular vesicles as a diagnostic biomarker for diabetic kidney disease
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PS10.05 - Isolation of circulating extracellular vesicles and cfDNA allows for ERBB2 detection in a single aliquot of breast cancer patients plasma
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PS11: Single EV Analysis
PS11 - PS11: Single EV Analysis
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PS11.02 - Fluorescence-based strategies for EVs quantification, characterization and assay development
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PS11.04 - Subpopulations of tissue-derived extracellular vesicles – methodological evaluation for vesicle size measurement
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PS11.05 - Imaging of human plasma-derived small-extracellular vesicles using Transmission Electron Microscopy and Structured Illumination Microscopy
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PS11.07 - Fabrication of nanopore structures via conformal metal-film deposition for EV sensing
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PS11.08 - Dimensional reduction of multi-parametric flow cytometry data reveals existence of distinct extracellular vesicle subpopulations
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PS11.09 - Detection and Quantification of Extracellular Vesicles with Cargo Protein and RNA Using the Amnis® CellStream® Flow Cytometer
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PS11.10 - Single EV imaging reveals novel EV biomarkers and DNA cargo
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PS12: EVs in Musculoskeletal System- Bone, Muscle, Tendon
PS12 - PS12: EVs in Musculoskeletal System- Bone, Muscle, Tendon
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PS12.01 - Extracellular vesicles, microRNA and muscle damage
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PS12.02 - Pulsed electromagnetic fields potentiate the paracrine function of mesenchymal stem cells for cartilage regeneration
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PS12.03 - Effects of extracellular vesicles from blood derivatives on osteoarthritic chondrocytes within an inflammation model
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PS12.06 - 1α,25(OH)2D3 Regulates Growth Cartilage Matrix Vesicle microRNAs
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PS13: Advances in Characterization of EV-Associated Molecules
PS13 - PS13: Advances in Characterization of EV-Associated Molecules
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PS13.01 - Evaluating the impact of culture conditions on human mesenchymal stromal cell-derived extracellular vesicles molecular fingerprint through FTIR spectroscopy
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PS13.02 - Performance Qualification for MicroFlow Cytometers: Understanding technical limitations to improve your research
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PS13.03 - Operating guidelines to determine the size and concentration of extracellular vesicles with microfluidic resistive pulse sensing
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PS13.04 - Real-time measurements of extracellular vesicles binding kinetics achieved through interferometric imaging in a multiplexed microarray modality
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PS13.06 - Spectral methods for EV detection in diabetic renal complications
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PS13.07 - Charge Detection Mass Spectrometry Measurements of Exosomes and other Extracellular Particles Enriched from Bovine Milk
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PS13.08 - In situ Detection of Exosomal microRNA-10b by Fusion with Liposome-Encapsulated Nanomotor
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PS13.09 - Isolation of exosomes by membrane affinity column increases non-exosomal RNA recovery in comparison to differential ultracentrifugation
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PS13.10 - Fluorescent Extracellular Vesicle characterisation using a long lasting cell tracker probe
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PS13.11 - Multiplex Electrochemiluminescence Immunoassays for Phenotyping of Intact Extracellular Vesicles (EVs)
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PS13.12 - Detection of MISEV recommended EV protein-markers using automated western blotting
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PS13.13 - AL-PHA beads: a library of extracellular vesicle-associated metalloproteinase biosensors
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PS14: Scholarship and Funding Opportunities
PS14 - PS14: Scholarship and Funding Opportunities
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PS14.01 - Program to assess the rigor and reproducibility of extracellular vesicle-derived analytes for cancer detection
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PS15: Oral with Poster Session 3: Neurological & ID
PS15.01=OP3.01 - Mitovesicles: a new extracellular vesicle of mitochondrial origin altered in aging and neurodegeneration
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PS15.02=OP3.02 - Reducing extracellular vesicle release with a novel neutral sphingomyelinase 2 inhibitor for the treatment of Alzheimer’s disease
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PS15.03=OP3.03 - Profiling EVs in the anterior cingulate cortex of individuals with major depressive disorder
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PS15.05=OP3.05 - L1CAM is not associated with extracellular vesicles in cerebrospinal fluid or plasma
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PS15.06=OP3.06 - An in vitro and in vivo perspective on the role of erythrocyte-derived extracellular vesicles in Parkinson's disease pathology
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PS15.07=OP3.07 - Exosomes from N-Myc amplified neuroblastoma cells induce migration and confer chemoresistance to non-N-Myc amplified cells: implications of intra-tumour heterogeneity
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PS15.08=OP3.08 - Dissecting the heterogeneity of extracellular vesicle sub-populations at single vesicle level
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PS15.09=OP3.09 - Proteomic analysis of EVs from the filamentous fungal plant pathogens Fusarium graminearum and Fusarium oxysporum f. sp. vasinfectum
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PS15.10=OP3.10 - Trypanosoma cruzi releases different types of extracellular vesicles that distinctly modulate host cells
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PS15.11=OP3.11 - Commensal bacterial extracellular vesicles act as carriers for norovirus
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PS15.13=OP3.13 - Detection of Bacterial Extracellular Vesicles in Blood from Healthy Volunteers
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PS15 - Oral with Poster Session 3: Neurological & ID
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PT01: EVs in the Central and Peripheral Nervous Systems
PT01 - PT01: EVs in the Central and Peripheral Nervous Systems
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PT01.01 - miR-451a highly expressed in extracellular vesicles secreted from Human fetal mesencephalic neural progenitor cells is one of key therapeutic factors for Parkinsonism multiple system atrophy
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PT01.03 - Patterns of apolipoproteins J , D and oxidative markers in circulating extracellular vesicles from MCI and Alzheimer’s patients
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PT01.04 - Extracellular vesicle biomarkers of complement activation and synaptic loss in Multiple Sclerosis
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PT01.05 - Methylglyoxal and glyoxal affect the protein cargoes in neuronal-derived extracellular vesicles
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PT01.06 - Cigarette Smoke Extract Alters Extracellular Vesicle Release and Circular RNA Expression
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PT01.07 - A method for exosomal RNA extraction from paired human brain and blood specimens
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PT01.08 - MicroRNAs from Adipocyte-derived Small Extracellular Vesicles are Associated with Neurodegeneration
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PT01.10 - Expression of Extracellular Vesicles after acute Traumatic Brain Injury: An Exploratory Flow-Cytometry Study
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PT01.11 - Enrichment of miR-451a in CNS extracellular vesicles following impairment of the blood brain barrier
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PT01.14 - Astrocyte-derived extracellular vesicles in morphine tolerance
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PT01.15 - Biophotonics-based platforms for the evaluation of circulating extracellular vesicles as biomarkers of neurodegeneration in Alzheimer’s disease
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PT01.16 - Raman profiling of extracellular vesicles as new blood-based biomarker for brain disorders: focus on Parkinson’s disease
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PT01.17 - Impact of circulating extracellular vesicles on brain functions and behaviors
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PT01.18 - MicroRNA profile of circulating extracellular vesicles are associated with upregulation of neuroinflammatiory signaling pathway in aged animals
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PT02: EVs in Dermatology
PT02 - PT02: EVs in Dermatology
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PT02.01 - Keratinocyte-derived exosomal packaging drives conversion of injury-site macrophage in granulation tissue of murine wound
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PT02.02 - Multifaced effects of Milk-exosome (Mi-Exo) as modulator of scar-free wound healing
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PT02.03 - Extracellular vesicles in human milk expose tissue factor and promote coagulation
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PT02.04 - Scalable isolation of EVs from different probiotic strains with potential as cosmetic ingredients
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PT02.07 - Acerola derived exosome-like nanovesicles enhances the repair of ultraviolet B-induced DNA damage in cultured skin fibroblasts
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PT03: Engineering and Loading EVs
PT03 - PT03: Engineering and Loading EVs
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PT03.01 - EV-mediated HOTAIR delivery for increased angiogenesis
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PT03.02 - Nanomaterial labeling of exosomes for cell biology
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PT03.03 - Loading of goat´s whey extracellular vesicles with spiked microRNA and curcumin as an strategy for developing new nanocarriers for acellular therapies
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PT03.04 - Development of novel tool for purification and characterization of extracellular vesicles in ageing and disease
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PT03.05 - Engineering exosomes with GATA-4
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PT03.06 - Chinese hamster ovary cells engineered for production of GFP-loaded extracellular vesicles
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PT03.07 - Manufacturing Extracellular Vesicles Derived from Human Mesenchymal Stromal Cells (MSC) in Bioreactors for Cancer Therapy
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PT03.08 - Biodistribution and cellular location of inhaled exosomes and liposomes in the lung
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PT03.10 - Transfection reagent artifact accounts for some reports of extracellular vesicle function
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PT04: EV Protein Biomarkers
PT04 - PT04: EV Protein Biomarkers
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PT04.01 - Cancer stem cell-derived exosomes: potential biomarkers for early diagnosis and prognosis in pancreatic cancer
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PT04.03 - Characterization of Extracellular vesicles separated from biospecimens of former national football League players at a risk for chronic traumatic encephalopathy
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PT04.04 - Density-based fractionation of urine to unravel the proteome landscape of extracellular vesicles in prostate cancer
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PT04.06 - Immunoglobulin A coating of feces-derived bacterial vesicles as a marker of inflammatory bowel disease in humans
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PT04.07 - Monitoring altered tetraspanin and PSMA expression in Prostate Cancer derived Extracellular Vesicles via Advanced Image Flow Cytometry (ISX)
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PT04.09 - Proteomic profiling of human neural cells derived extracellular vesicles to identify human brain cell-type specific markers
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PT04.11 - Quality control for bacterial EVs
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PT04.12 - Relationship of extracellular vesicle cargo with clinical markers of mortality and race
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PT04.13 - Repurposing specialised cell-free DNA blood collection tubes for extracellular vesicle isolation
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PT04.14 - Role of exosomes in the management of cellular disease in the genetic susceptible participants in the Chilean population
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PT04.15 - Subpopulations of EVs in serum and plasma
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PT04.16 - Tumor-derived extracellular vesicles contain distinct integrin proteins
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PT04.17 - Effect of nicotine and menthol on cytochrome P450 and antioxidant enzymes in rat plasma-derived extracellular vesicles
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PT04.18 - Proteomic signatures in breast cancer exosomes and cell lines
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PT04.19 - Circulatory EVs as potential biomarkers of HIV-drug abuse interactions and neurological dysfunction in HIV-Infected subjects and alcohol/tobacco Users
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PT04.20 - Electrochemical detection of miRNA-21-5p
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PT05: Advance in EV Quantitation
PT05 - PT05: Advance in EV Quantitation
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PT05.01 - Accurate EV Concentration is Critical for Experimental Rigor and Reproducibility
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PT05.02 - Clinically relevant synthetic reference materials to standardize concentration measurements of extracellular vesicles: state-of-the-art and future prospects
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PT05.03 - Comparison of Production and Activity of Amniotic Fluid Stem Cell Extracellular Vesicles from 3D Hollow Fiber Bioreactor and 2D culture.
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PT05.04 - Demonstration of High Gain mode in combination with Imaging Flow Cytometry for improved EV analysis
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PT05.05 - Distance-controlled accelerated catalyzed hairpin DNA circuit for multiple and sensitive detection of exosomes-associated miRNAs
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PT05.06 - Impact of isolation methods on biophysical heterogeneity of single extracellular vesicles
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PT05.08 - Ready-to-use, pre-labeled and stable human EVs for validating new standardization procedures of EV concentration measurements
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PT05.09 - Understanding Intracellular Fate of EV-delivered Content
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PT05.10 - Theoretical model of EV losses due to adsorption on the tube walls. Application for immunomagnetic detection of the vesicles
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PT05.11 - Videodrop by Myriade : The use of interferometric microscopy to quantify vesicles in complex samples such as fecal filtrates
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PT06: EVs in Stem Cells (including Cancer Stem Cells)
PT06 - PT06: EVs in Stem Cells (including Cancer Stem Cells)
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PT06.02 - Characterization of small extracellular vesicles produced by human mesenchymal stromal cells in an improved extracellular vesicle-free medium
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PT06.03 - Comparison of classical and imaging flow cytometry platforms for the characterization of stem cell-derived extracellular vesicles
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PT06.04 - Evaluation of ATCC’s exosomes from cell culture supernatant as reference standards in research and development.
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PT06.05 - Exo-cise: Extracellular vesicles enriched from plasma post-exercise promotes myogenesis and neurogenesis
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PT06.07 - Extracellular Vesicle Characterization in Human Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium
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PT06.08 - Increased VEGF Secretion from MSC Cell Culture in Normoxic Condition
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PT06.09 - Isolation and characterization of exosomes from canine stem cells
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PT06.10 - Mesenchymal stem cells-derived exosomes promote in vitro the progression of triple negative breast cancer cells
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PT06.11 - Natural killer cell-derived extracellular vesicles have a potent anti-leukemic effect and selectively target the cancer stem cell subpopulation
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PT06.12 - Scalable Manufacturing System for MSC-EV Generation
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PT06.13 - Simplifying Scalable MSC EV Production in a Microcarrier-Based Bioreactor System
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PT06.15 - The whitening, anti-wrinkle, and wound-healing effects of Extracellular vesicles from Orbicularis oculi muscle-derived stem cells.
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PT06.16 - Use of Stem Cell Extracellular Vesicles as a Holistic Approach Towards CNS Repair
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PT06.17 - The effect of cell culture media on extracellular vesicle secretion from mesenchymal stem cells and human pluripotent stem cell-derived neurons
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PT06.18 - Mouse mesoangioblast stem cell extracellular vesicles are able to influence macrophage cell activity
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PT07: EV Biogenesis (from Prokaryotes to Euraryotes), Component Loading, and Release
PT07 - PT07: EV Biogenesis (from Prokaryotes to Euraryotes), Component Loading, and Release
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PT07.01 - Analytical ultracentrifugation identifies distinct populations of extracellular vesicles (EVs) carrying the evolutionarily-conserved polycystin-2 protein in C. elegans
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PT07.02 - C. elegans ciliated sensory neurons release distinct subpopulations of extracellular vesicles
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PT07.03 - Ceramide accumulation induces exosome secretion through lysosomal protein LAPTM4B
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PT07.05 - Evaluation of culture conditions on the presence of Ago2 in extracellular vesicles
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PT07.07 - Extracellular vesicles secreted from melanoma cell lines contain similar gangliosides and associated molecules with lipid rafts on the cellular membrane
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PT07.08 - Hypoxia alters the metabolic and miRNA content of breast cancer-derived exosomes
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PT07.09 - Lysosomotropic agents prompts the release of extracellular vesicles carrying autophagy-associated markers: evidence of a general mechanism of secretion driven by lysosomal impairment
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PT07.10 - Roles of Extracellular Vesicles for Lenalidomide-Resistance in Multiple Myeloma
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PT07.11 - Study on Biological Stimulate Mechanism of Stem cell-derived Exosome Generation by Nanoparticles
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PT07.12 - Theoretical description of formation of extracellular vesicles by budding of membrane
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PT07.13 - Role of Arrdc4-mediated ubiquitination in extracellular vesicle biogenesis and protein trafficking
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PT08: Scientific Outreach and Collaboration
PT08 - PT08: Scientific Outreach and Collaboration
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PT08.01 - A 3D-printed model to represent the structure and nature of extracellular vesicles, for public engagement and education events.
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PT08.02 - Centrifugal filtration-SEC is promising for extracellular vesicle isolation from D492 and D492HER2+ breast epithelial cell lines
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PT08.03 - Customer stories from the EV Core of University of Helsinki
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PT08.04 - Recent ISEV Workshops: Open, reproducible and standardized EV research (Ghent, 2019) and EVs in immunology (Buenos Aires, 2020)
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PT08.05 - EV Journal Club: exchanging pizza for a worldwide audience during COVID-19
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PT09: EV Immunology, Autoimmunity, and Inflammation
PT09 - PT09: EV Immunology, Autoimmunity, and Inflammation
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PT09.01 - Air pollution exposure and allergic rhinitis exacerbation: the role of nasal microbiota and extracellular vesicle communication
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PT09.03 - Aryl hydrocarbon receptor activation induces the expression of specific MicrorRNAs in Th17 cells that are release into extracellular vesicules and associated with arthritis
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PT09.08 - Extracellular Vesicles released by Trypanosoma cruzi trypomastigotes under different stress conditions
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PT09.09 - Immuno-toxicological Evaluation of Human Mesenchymal Stem Cell-derived Extracellular Vesicles
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PT09.11 - Investigation of immune response to mesenchymal stem cell-derived extracellular vesicles in the cancer setting
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PT09.12 - Outer membrane vesicles of Mycobacterium avium modulate inflammatory response in monocytes
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PT09.13 - Sepsis Alters the Differential Expression of microRNA in Platelet-Derived Small Extracellular Vesicles of Pediatric Patients
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PT09.14 - T cell-exosome-derived miR-142-3p impairs glandular cell function in Sjögren´s syndrome
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PT09.15 - Treg-Derived IL35-Coated Extracellular Vesicles Promote Infectious Tolerance
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PT09.16 - Unique formulated dual targeting antigen specific and delivered miRNA-150 gene regulating exosomes acting at the immune synapse to induce APC-derived secondary suppressive exosomes
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PT09.17 - The role of Mac-1 and calcium signaling in the formation of neutrophil granulocyte derived extracellular vesicles
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PT09.18 - Extracellular vesicles and their microRNA cargo in retinal health and degeneration: mediators of homeostasis, and immune modulation
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PT09.19 - Impacts of Agricultural Dust Exposure on Human Lung-Resident Mesenchymal Stromal/stem Cells and their Extracellular Vesicles
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PT10: Single-EV Analysis
PT10 - PT10: Single-EV Analysis
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PT10.03 - Clinically applicable method to avoid swarm detection during flow cytometry analyses of single extracellular vesicles in human plasma
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PT10.05 - Benchmarking flow cytometric analysis of nanoparticles: a cross-platform study for single extracellular vesicle detection
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PT10.07 - Caution when Using Membrane Dyes for Sequential Extracellular Vesicle Analysis
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PT10.08 - Correlation between size and protein expression of single exosomes by combined atomic force and fluorescence microscopy
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PT10.09 - Development of a panel of antibodies for capture and labeling of EVs from neural cell types
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PT11: EVs in Cardiovascular Diseases and Vascular Disorders
PT11 - PT11: EVs in Cardiovascular Diseases and Vascular Disorders
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PT11.01 - Association between circulating extracellular vesicles and thrombogenic risk markers for cardiovascular disease
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PT11.02 - Beyond stem cells: extracellular vesicles from human induced pluripotent stem cells (hiPSC) and hiPSC-cardiomyocytes as therapeutic approaches for heart failure
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PT11.03 - Endothelial cells differentially load and secrete extracellular vesicle-derived microRNAs into apical and basolateral compartments
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PT11.08 - Insights into EV subpopulations positive and negative for Annexin A1 from smooth muscle cells and valvular interstitial cells
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PT11.09 - Possibility of Exosomal MicroRNAs Associated with Chronic Limb-Threatening Ischemia, the End stage of Atherosclerosis, as a promising Biomarker
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PT11.10 - Postoperative plasma exosomal miR-21 and miR-133a signature in patients with left ventricular reverse remodeling after surgical mitral valve repair
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PT11.11 - Expression of lipocalin-2 (LCN2) in circulating extracellular vesicles (EVs) and femoral plaque-derived EVs of peripheral arterial disease patients.
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PT11.12 - Cardioprotective effects of extracellular vesicles from immortalized parental stromal cells: a translational strategy
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PT12: Biodistribution, Signaling, and ECM
PT12 - PT12: Biodistribution, Signaling, and ECM
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PT12.01 - Acinetobacter baumannii transfers the efflux pump related substances via outer membrane vesicles
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PT12.02 - Characterization of melanocytic extracellular vesicles during aging of the choroid
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PT12.03 - Extracellular vesicle heterogeneity and the impact of cellular phenotypic drift on the vesicular proteome
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PT12.05 - In vivo tracking and biodistribution analysis of mesenchymal stem cell-derived extracellular vesicles in a radiation injury murine model
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PT12.06 - Linking fat to colorectal cancer: extracellular vesicle crosstalk
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PT12.08 - Regulation of cellular senescence by Interferon Induced Transmembrane Protein 3 contained in small Extracellular Vesicles
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PT12.09 - Stiff Matrix Induces Exosome Secretion and Promotes Tumor Progression
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PT12.11 - Tridimensional fibroblast culture revealed a novel exososome-dependent extracellular matrix secretion mechanism
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PT12.12 - Redirected tropisms of extracellular vesicles and exomeres yield distinct biodistribution profiles
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PT12.13 - TRACKING MESENCHYMAL STEM CELL-DERIVED EXTRACELLULAR VESICLES (EVs) IN A IN VIVO CANCER MODEL
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Pt12.15 - Response To Irradiation Of Small Extracellular Vesicles Derived From Prostate Tumors
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PT13: Advances in EV Separation and Concentration
PT13 - PT13: Advances in EV Separation and Concentration
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PT13.01 - Development and characterization of extracellular vesicles separation methods from human brain tissues and its application to Alzheimer’s disease
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PT13.07 - EDTA stabilizes the concentrations of extracellular vesicles during blood collection
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PT14: Microfluidic and Other Devices
PT14 - PT14: Microfluidic and Other Devices
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PT14.03 - Circular Dichroism-based Exosome (CDEXO) detection microfluidic platform using their assemblies with chiral gold nanoparticles
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PT14.04 - EV classification and fractionation strategy using surface charge labeling
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PT14.05 - High throughput exosome analysis by using reversible microfluidic electrochemical sensor system
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PT14.06 - High-throughput multiparametric characterization and quantitation of extracellular vesicles by fluorescence-based microfluidic diffusion sizing
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PT14.07 - Immunomagnetic isolation of specific subpopulations of exosomes for liquid biopsy via nano-architected porous materials
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PT14.09 - Micropatterned Growth Surface Topography Affects Extracellular Vesicle Production
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PT14.10 - Using miscroscale thermophoresis and surface plasmon resonance to measure the interactions of extracellular vesicles
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PT14.11 - Acoustofluidic separation of complex suspensions
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PT14.12 - Nanophotonic platform for cancer-associated exosomal microRNA detection
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PT15: Oral with Poster Session 1: Lungs
PT15.01=OP1.01 - Human urinary extracellular vesicles carry surface markers that are indicative of hematopoietic origin
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PT15.02=OP1.02 - Cardiovascular risk markers are strongly related to numbers of circulating extracellular vesicles
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PT15.03=OP1.03 - Extracellular vesicles from cardiosphere-derived cells potentiate regulatory T cells
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PT15.04=OP1.04 - Prostanoids impair platelet reactivity, thrombus formation and platelet extracellular vesicle release in patients with pulmonary arterial hypertension
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PT15.05=OP1.05 - Nanoflow cytometry identifies an imbalance of epithelium- and neutrophil-derived extracellular vesicles in the airway environment of pediatric cystic fibrosis patients
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PT15.06=OP1.06 - The potential of crude extracellular vesicle microRNAs for the diagnosis of community-acquired pneumonia and for the detection of pneumonia-related sepsis as a severe secondary complication
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PT15.07=OP1.07 - microRNA exosome cargo from induced sputum: new tool for approaching asthma research
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PT15.08=OP1.08 - Human nrf2-active multipotent stromal cell exosomes reverse pathologic delay in the healing of cutaneous diabetic wounds
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PT15.12=OP1.12 - Extracellular vesicles from adipose tissue end endothelial cells of obese humans share miRNA cargos and increase prostate cancer aggressiveness in conjunction with Twist1
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PT15 - Oral with Poster Session 1: Lungs
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Sponsored Poster Session
Beckman Coulter Life Sciences
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Cellarcus Biosciences
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Cytek Biosciences
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FUJIFILM Wako Pure Chemical Corporation
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IMMUNOSTEP S.L.
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Luminex Corporation
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Malvern
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MYRIADE
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NanoFCM INC.
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NanoView Biosciences
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Particle Metrix
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RoosterBio, Inc.
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Spectradyne LLC
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Streck
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System Bio
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Symposium Session 06: MSC EV Therapeutics
OT06.6 - Changes in extracellular vesicle protein cargo after pro-inflammatory priming of umbilical cord mesenchymal stem cells
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