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Basic EV Biology
On Demand

OT03.2 - Towards identification of protein components mediating cardiac repair by cardiac progenitor cell-derived extracellular vesiclesMarieke T. Roefs, M.T. – Department of Experimental Cardiology, University Medical Center Utrecht, Utrecht University, The Netherlands; Pieter Vader – Laboratory of Clinical Chemistry and Hematology, UMC Utrecht; Department of Experimental Cardiology, UMC Utrecht, The Netherlands; Joost Sluijter, J.P.G. – Department of Experimental Cardiology, University Medical Center Utrecht, Utrecht University, The Netherlands; Joost Sluijter, J.P.G. – Department of Experimental Cardiology, University Medical Center Utrecht, Utrecht University, The Netherlands
On Demand

OT04.1 - Endo-lysosomes as an alternative intracellular location for EV cargo delivery with disease relevanceGiona Pedrioli, MSc – Laboratory for Biomedical Neurosciences, LBN-EOC; Marialuisa Barberis – Laboratory for Biomedical Neurosciences, LBN-EOC; Diego Morone – Istituto di Ricerca in Biomedicina; Paolo Paganetti – Laboratory for Biomedical Neurosciences, LBN-EOC
On Demand

OT04.3 - Anti-human Fab fragment of CD9 antibody prevents the endocytosis of melanoma and colon cancer-derived extracellular membrane vesicles and nuclear transfer of their cargosAurelio Lorico, MD, PhD – Touro University Nevada College of Medicine; Mark Santos – Touro University College of Medicine; Jana Karbanová – Technische Universität Dresden; Kevin Huang – Touro University Nevada College of Medicine; Tony Huynh – Touro University Nevada College of Medicine; Gyunghwi Woo – Touro University Nevada College of Medicine; Cheryl Vanier – Touro University Nevada; Chikao Morimoto – Juntendo University; Germana Rappa – Touro University Nevada College of Medicine; Denis Corbeil – Tissue Engineering Laboratories, Technische Universität Dresden,; Aurelio Lorico, MD, PhD – Touro University Nevada College of Medicine
On Demand

OT04.4 - A bright, versatile reporter for multivesicular body trafficking and exosome secretion and uptakeBong Hwan Sung, MSc, PhD – Department of Cell and Developmental Biology, Vanderbilt University; Ariana von Lersner – Vanderbilt University; Jorje Guerrero – University of Wisconsin-Madison; Evan Krystofiak – Vanderbilt University; David Inmann – University of Wisconsin-Madison; Roxanne Pelletier – Vanderbilt University; Andries Zijlstra – Vanderbilt University Medical Center; Suzanne Ponik – University of Wisconsin-Madison; Alissa Weaver – Department of Cell and Developmental Biology, Vanderbilt University School of Medicine
On Demand

OT04.5 - Uncovering novel genes regulating EV-mediated functional RNA transfer using a CRISPR/Cas9-based reporter systemOlivier G. de Jong, PhD – Laboratory of Clinical Chemistry and Hematology, UMC Utrecht, The Netherlands; Daniel E. Murphy, MSc – Laboratory of Clinical Chemistry and Hematology, UMC Utrecht; Imre Mäger – Department of Paediatrics, University of Oxford; Eduard Willms – La Trobe University; Sander A.A Kooijmans, PhD – CDL Research, University Medical Center Utrecht, The Netherlands; Jacco van Rheenen – Department of Molecular Pathology, Oncode Institute, Netherlands Cancer Institute; Raymond M. Schiffelers – Laboratory of Clinical Chemistry and Hematology, UMC Utrecht, The Netherlands; Samir El-Andaloussi – Department of Laboratory Medicine, Clinical Research Center, Karolinska Institutet; Matthew J.A. Wood – Department of Paediatrics, University of Oxford; Pieter Vader – Laboratory of Clinical Chemistry and Hematology, UMC Utrecht; Department of Experimental Cardiology, UMC Utrecht, The Netherlands
On Demand

OT04.6 - Quantitative characterization of Extracellular Vesicle Uptake and Content Delivery within Mammalians Cellsgregory lavieu, PhD – INSERM U132/Institut Curie; gregory lavieu, PhD – INSERM U132/Institut Curie; emeline Bonsergent – Institut Curie/ Universite de Paris; eleonora grisard – institut Curie; Clotilde Théry, MD PhD – INSERM U932, Institut Curie, PSL Research university
On Demand

OT09.1 - Ubiquitin E3 ligase NEDD4 is a novel regulator of exosome biogenesis and secretionIshara Atukorala, PhD – La Trobe Institute for Molecular Science; Sushma Anand, n/a – Monash University; David Chisanga, n/a – University of Melbourne; Guillaume van Niel, PhD – Institute of Psychiatry and Neurosciences of Paris U-1266 INSERM; Sharad Kumar, n/a – University of South Australia; Suresh Mathivanan – La Trobe University
On Demand

OT09.2 - Fragmentation of extracellular ribosomes and tRNAs shapes the extracellular RNAomeJuan P. Tosar, PhD – Universidad de la República, Uruguay; Juan P. Tosar, PhD – Universidad de la República, Uruguay; Mercedes Segovia – Laboratory of 9 Immunoregulation and Inflammation, Institut Pasteur de Montevideo, Uruguay.; Fabiana Gámbaro – Functional Genomics Unit, Institut Pasteur de Montevideo, Uruguay; Yasutoshi Akiyama – Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, USA. Department of Medicine, Harvard Medical School, Boston, MA, USA.; Pablo Fagúndez – Analytical Biochemistry Unit. Nuclear Research Center. Faculty of Science. Universidad de la República, Uruguay.; Bruno Costa – Analytical Biochemistry Unit. Nuclear Research Center. Faculty of Science. Universidad de la República, Uruguay.; Tania Possi – Functional Genomics Unit, Institut Pasteur de Montevideo, Uruguay; Marcelo Hill – Laboratory of Immunoregulation and Inflammation, Institut Pasteur de Montevideo, Uruguay.; Pavel Ivanov – Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, USA. Department of Medicine, Harvard Medical School, Boston, MA, USA; Alfonso Cayota – Functional Genomics Unit, Institut Pasteur de Montevideo, Uruguay
On Demand

OT09.3 - CD47 interactions with exportin-1 regulate targeting of m7G-capped RNAs to extracellular vesiclesSukbir Kaur, PhD – National Cancer Institutes; Alejandra Cavazos Saldana – Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, USA; Abdel G. Elkahloun – Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, USA; Jennifer D. Petersen, PhD – Section on Integrative Biophysics, Division of Basic and Translational Biophysics, Eunice Kennedy-Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, USA; Anush Arakelyan – Section on Intercellular Interactions, Division of Basic and Translational Biophysics, Eunice Kennedy-Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda,; Satya P. Singh – Inflammation Biology Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, USA.; Lisa M Jenkins – Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, USA; Bethany Kuo – Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, USA; Bianca Reginauld – Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, USA; David G Jordan – Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, USA; Andy D Tran – Confocal Microscopy Core Facility, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, USA; Weiwei Wu – Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, USA; Joshua Zimmerberg – Section on Integrative Biophysics, Division of Basic and Translational Biophysics, Eunice Kennedy-Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, USA; Leonid Margolis – Section on Intercellular Interactions, Division of Basic and Translational Biophysics, Eunice Kennedy-Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, USA; David D. Roberts – Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, USA
On Demand

OT09.5 - Role of membrane protein palmitoylation in extracellular vesicle biogenesis in squamous cell carcinomaMohammed Haque – Thomas Jefferson University; Joseph P. Flemming – Thomas Jefferson University; Brianna L. Hill – Thomas Jefferson University; James Wahl – UNMC; My Mahoney – Thomas Jefferson University
On Demand

OT09.6 - Translation initiation factor eIF4E reprograms the vesiculation of cancer cellsEsterina D'Asti – University of Montreal; Biljana Culjkovic-Kraljacic – University of Montreal; Héloïse Chassé – University of Montreal; Jadwiga Gasiorek – University of Montreal; Gavin Morris – University of Montreal; Katherine Borden – University of Montreal
On Demand

OT10.6 - lncRNA EPHA6-1 in IFNβ-induced small extracellular vesicles promotes cytotoxicity of NK cells by acting as a ceRNA for hsa-miR-4485 to up-regulate NKp46 expressionShuang Li – Institute of Blood Transfusion, Peking Union Medical College; Anjing Zhu – Institute of Blood Transfusion, Chinese Academy of Medical Sciences Peking Union Medical College; Shilin Li – Institute of Blood Transfusion, Chinese Academy of Medical Sciences Peking Union Medical College; Limin Chen – Institute of Blood Transfusion, Chinese Academy of Medical Sciences Peking Union Medical College
On Demand

OT11.1 - Unbiased quantitative proteomic analysis identifies novel cellular components specifically incorporated into endogenous EV subtypes, HIV-1 particles and virus-modified EVslorena Martin-Jaular – INSERM U932, Institut Curie, PSL Research university; Nathalie Nevo – INSERM U932, Institut Curie, PSL Research university; mercedes tkach – INSERM U932, Institut Curie, PSL Research university; mabel jouve – CNRS UMR3215, Institut Curie, PSL Research university; Florent Dingli – Institut Curie, PSL Research University, Laboratoire de Spectrométrie de Masse Protéomique; damarys loew – Institut Curie, PSL Research University, Laboratoire de Spectrométrie de Masse Protéomique; Kenneth Witwer – Department of Molecular and Comparative Pathobiology and Department of Neurology, The Johns Hopkins University School of Medicine; matias ostrowski – Instituto INBIRS, Universidad de Buenos Aires-CONICET; georg borner – Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry,; Clotilde Théry, MD PhD – INSERM U932, Institut Curie, PSL Research university; lorena Martin-Jaular – INSERM U932, Institut Curie, PSL Research university
On Demand

OT11.6 - Who comes out first: Extracellular Vesicles (EV) or Viruses?Fatah Kashanchi, PhD – Laboratory of Molecular Virology, School of Systems Biology, George Mason University, Manassas, VA; Yuriy Kim – George Mason University; Daniel Pinto – George Mason University; Gifty Mensah – George Mason University; Maria Cowen – George Mason University; James Erickson – George Mason University; Michelle Pleet – George Mason University; Catherine DeMarino – George Mason University; Renaud Mahieux – Superieure de Lyon, Université
On Demand

OF12.3 - A novel in vivo Drosophila model of vesicle-mediated intercellular communicationClaire M. Hill – University of Oxford; Elizabeth Dellar – University of Oxford/Oxford Brookes University; Jana Terenova – University of Oxford; Monika Gullerova – University of Oxford; David R F. Carter – Oxford Brookes University; Luis Alberto Baena-Lopez – University of Oxford
On Demand

OF12.5 - Bacterial membrane vesicles (MVs) — a bacterial innate defense system against viral infectionXiaomei Yan, PhD – Xiamen University; Qian Niu – Xiamen University; Ye Tian – Xiamen University
On Demand

OF12.7 - In vivo tracking of extracellular vesicles: comparison across radioactive, fluorescence and bioluminescence approachesElisa Lázaro-Ibáñez, PhD – Advanced Drug Delivery, BioPharmaceuticals R&D, AstraZeneca; Farid N. Faruqu – Institute of Pharmaceutical Science, King's College London; Amer Saleh – Clinical Pharmacology & Safety Sciences, Biopharmaceuticals R&D, AstraZeneca; Andreia M. Silva, PhD – AstraZeneca R&D; Khuloud Al-Jamal – Institute of Pharmaceutical Science, King’s College London; Niek Dekker – Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca
On Demand

OF13.5 - High-resolution size-based profiling and morphological analysis of extracellular vesicles by scanning electron microscopySara Cavallaro, MS – KTH Royal Institute of Technology; Federico Pevere – Uppsala University; Petra Hååg – Karolinska Institute; Kristina Viktorsson – Karolinska Institute; Rolf Lewensohn – Karolinska Institute; Jan Linnros – KTH Royal Institute of Technology; Apurba Dev – Uppsala University
On Demand

OF13.6 - Detailed Characterization of how different extracellular vesicles isolation methods results in different amount of Periostin protein association.Carolina Balbi, PhD – Cardiocentro Ticino; Edoardo Lazzarini – Cardiocentro Ticino; Emanuel Fertig – Victor Babes National Institute of Pathology; Mihaela Gherghiceanu – Victor Babes National Institute of Pathology; Lucio Barile – Cardiocentro Ticino; Giuseppe Vassalli – Cardiocentro Ticino
On Demand

OF14.4 - Presence of vault RNA and proteins indicates contamination of extracellular vesicle preparations with vault particlesXinming Liu, MSc(Res) – The University of Sheffield; Daniel Lambert – The University of Sheffield; Stuart Hunt – The University of Sheffield; Stuart Hunt – The University of Sheffield
On Demand

OF14.5 - Staphylococcus aureus secrete immunomodulatory RNA and DNA via extracellular vesiclesBlanca V. Rodriguez, MS – Duke University; Meta Kuehn – Duke University
On Demand

OF18.1 - Glycolytic restraint in alveolar macrophages is critical for vesicular secretion of suppressor of cytokine signaling 3Mikel D. Haggadone – University of Michigan Medical School; Jennifer Speth – University of Michigan Medical School; Hanna Hong – University of Michigan Medical School; Eric Zhang – University of Michigan; Costas Lyssiotis – University of Michigan Medical School; Marc Peters-Golden – University of Michigan Medical School
On Demand

OF18.2 - Cyanobacterial extracellular vesicles are an alternative secretion mechanism to deal with copper-induced stressSteeve S. Lima, MSc – i3S/IBMC (Porto, Portugal); Joaquin Giner-Lamia – Centre for Plant Biotechnology and Genomics; Francisco Florencio – Plant Biochemistry and Molecular Biology, Universidad de Sevilla; Narciso Couto – Department of Chemical and Biological Engineering, University of Sheffield; Phillip Wright – School of Chemical Engineering and Advanced Materials, Newcastle University; Paula Tamagnini – Faculdade de Ciências, Departamento de Biologia, Universidade do Porto; i3S/IBMC; Paulo Oliveira – i3s/IBMC
On Demand

OF18.3 - Ciliary EV cargo sorting and biogenesis in living animalsJuan Wang, PhD – Rutgers University, Human Genetics Institute of NJ; Maureen Barr – Rutgers University, Human Genetics Institute of NJ
On Demand

OF18.4 - Comparative proteomics from different cancer cell types reveals novel mechanisms of Rab11-exosome subtype regulationPauline Marie – University of Oxford; Shih-Jung Fan, MD PhD – University of Oxford; John Mason – University of Oxford; Claudia Mendes – University of Oxford; Mark Wainwright, MD PhD – University of Oxford; Adrian Harris – University of Oxford; Clive Wilson – University of Oxford; Deborah C I Goberdhan, PhD – University of Oxford; Deborah C I Goberdhan, PhD – University of Oxford
On Demand

OF18.5 - Three-dimensional culture models to elucidate exosomal biologyKathleen M. McAndrews – UT MD Anderson Cancer Center; Fei Xiao – UT MD Anderson Cancer Center; Valerie LeBleu – UT MD Anderson Cancer Center; Raghu Kalluri – Department of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center
On Demand

OF18.6 - Extracellular vesicles derived from R345W-Fibulin-3 retinal pigment epithelial cells promote epithelial-mesenchymal transitionMi Zhou, MD – Penn State Hershey Medical Center; Stephanie Grillo – Penn State Hershey Medical Center; Sarah Weber – Penn State Hershey Medical Center; Yuanjun Zhao – Penn State Hershey Medical Center; Jeffrey Sundstrom – Penn State Hershey Medical Center
On Demand

OS21.3 - Exosomes in filopodia formationCaitlin McAtee, PhD – Vanderbilt University; Daisuke Hoshino – Kanagawa Cancer Center Research Institute; Nan Hyung Hong – Fred Hutchinson Cancer Research Center; Bong Hwan Sung, MSc, PhD – Department of Cell and Developmental Biology, Vanderbilt University; Ariana von Lersner – Vanderbilt University; Andries Zijlstra – Vanderbilt University Medical Center; Alissa Weaver – Department of Cell and Developmental Biology, Vanderbilt University School of Medicine
On Demand

OS21.6 - Astrocyte-derived EV-mediated blood-brain barrier disruptionShilpa Buch, PhD – University of Nebraska Medical Center; Ke Liao – University of Nebraska Medical Center; Susmita Sil – University of Nebraska Medical Center; Fang Niu – University of Nebraska Medical Center; Guoku Hu, PhD – University of Nebraska Medical Center
On Demand

OS22.6 - Sequence-specific RNA trafficking to Extracellular Vesicles is conserved across cell typesAndreia M. Silva, PhD – AstraZeneca R&D; Olga Shatnyeva – Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca; Elisa Lázaro-Ibáñez, PhD – Advanced Drug Delivery, BioPharmaceuticals R&D, AstraZeneca; Molly Stevens – Department of Materials, Department of Bioengineering and Institute for Biomedical Engineering, Imperial College London; Department of Medical Biochemistry and Biophysics, Karolinska Institutet; Niek Dekker – Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca
On Demand

OS23.3 - Synergy between 15-lipoxygenase and secreted PLA2 promotes inflammation by formation of TLR4 agonists from extracellular vesiclesMateja Manček Keber – National Institute of Chemistry; Van Thai Ha – National Institute of Chemistry; Duško Lainšček – National Institute of Chemistry; Bernd Gesslbauer – University of Graz; Eva Jarc – Jožef Stefan Institute; Tuulia Hyötyläinen – Örebro University; Nejc Ilc – University of Ljubljana; Katja Lakota – University Medical Centre Ljubljana; Matija Tomšič – University Medical Centre Ljubljana; Fons A.J. van de Loo – Radboud University Medical Center; Valery Bochkov – University of Graz; Toni Petan – Jožef Stefan Institute; Roman Jerala – National Institute of Chemistry
On Demand

OS23.5 - Microglial derived extracellular vesicles activate autophagy and mediate multi-target signaling to maintain cellular homeostasisBram Van den Broek – Hasselt university; Isabel Pintelon – Antwerp university; Ibrahim Hamad – Hasselt university; Mansour Haidar – Hasselt University; Niels Hellings – Hasselt University; Jerome Hendriks – Hasselt University; Markus Kleinewietfeld – Hasselt University; Jean-Pierre Timmermans – Antwerp University; Vincent Timmerman – Antwerp university; Veerle Somers – Hasselt University; Luc Michiels – Hasselt University; Joy I. Irobi, PhD – Hasselt University; Joy I. Irobi, PhD – Hasselt University
On Demand

OS24.4 - Characterization of EVs using orthogonal techniques identifies discrete EV populations from a mouse dendritic cell lineBryce Killingsworth – Laboratory of Pathology, National Cancer Institute, National Institutes of Health; Timothy Traynor – Laboratory of Pathology, National Cancer Institute, National Institutes of Health; Joshua A. Welsh – Laboratory of Pathology, National Cancer Institute, National Institute of Health; Aleksandra Dakic – Laboratory of Pathology, National Cancer Institute, National Institutes of Health; Jason Savage – Laboratory of Pathology, National Cancer Institute, National Institutes of Health; Kevin Camphausen – Radiation Oncology Branch, National Cancer Institute, National Institutes of Health; Kenneth Aldape – Laboratory of Pathology, National Cancer Institute, National Institutes of Health; Jennifer Jones – Laboratory of Pathology, National Cancer Institute, National Institutes of Health
On Demand

OS28.3 - Multi-compartmented microvesicles: novel extracellular secretory organelles that release exosomes and extracellular vesiclesJennifer D. Petersen, PhD – Section on Integrative Biophysics, Division of Basic and Translational Biophysics, Eunice Kennedy-Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, USA; Sukhbir Kaur – Laboratory of Pathology and Laboratory of Experimental Carcinogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health; Elena Mekhedov – Section on Integrative Biophysics, Division of Basic and Translational Biophysics, Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD, Bethesda, USA; David D. Roberts – Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, USA; Joshua Zimmerberg – Section on Integrative Biophysics, Division of Basic and Translational Biophysics, Eunice Kennedy-Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, USA
Monday, Jul 20
11:23 AM – 11:48 AM

The Mystery of EV Biogenesis – Past, Present, and FuturePhyllis Hanson – University of Michigan
Monday, Jul 20
12:35 PM – 12:36 PM

IntroductionAndrew Hill – The Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria, Australia.
Monday, Jul 20
12:36 PM – 12:49 PM

Featured Abstract: Ral GTPases promote metastasis by controlling biogenesis and organotropism of extracellular vesiclesshima ghoroghi – INSERM UMR_S1109, Tumor Biomechanics; Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France; Benjamin Mary – INSERM UMR_S1109, Tumor Biomechanics; Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France; Annabel LARNICOL – INSERM UMR_S1109, Tumor Biomechanics; Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France; François Delalande – LSMBO, Institut Pluridisciplinaire Hubert Curien, Strasbourg, France.; Christine Carapito – LSMBO, Institut Pluridisciplinaire Hubert Curien, Strasbourg, France; Nicodème Paul – INSERM UMR_S1109, Tumor Biomechanics; Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France; Raphael Carapito – INSERM UMR_S1109, Tumor Biomechanics; Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France; Olivier Lefebvre – INSERM UMR_S1109, Tumor Biomechanics; Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France; Jacky Goetz – INSERM UMR_S1109, Tumor Biomechanics; Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France; Vincent Hyenne – Tumor Biomechanics INSERM UMR_S 1109 Institut d’hématologie et d'immunologie,CNRS SNC5055, Strasbourg, France
Monday, Jul 20
1:53 PM – 2:04 PM

ISEV guidelines on EV studies (MISEV2018) and standardization initiativesClotilde Théry, MD PhD – INSERM U932, Institut Curie, PSL Research university; Kenneth Witwer – Department of Molecular and Comparative Pathobiology and Department of Neurology, The Johns Hopkins University School of Medicine
Tuesday, Jul 21
3:38 PM – 3:39 PM

IntroductionSusmita Sahoo – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai
Tuesday, Jul 21
3:39 PM – 3:49 PM

Nuclear proteins are recruited into tumor-derived extracellular vesicles upon expression of tetraspanin Tspan8Elena Grueso Navarro – Institute for Infection Prevention and Hospital Epidemiology; Medical Center-University of Freiburg, University of Freiburg, Freiburg, Germany; Andrea Gross – Institute for Infection Prevention and Hospital Epidemiology; Medical Center-University of Freiburg, University of Freiburg, Freiburg, Germany.; Amal Mohamed – Institute for Infection Prevention and Hospital Epidemiology; Medical Center-University of Freiburg, University of Freiburg, Freiburg, Germany.; Patrick Then – Leibniz Institute of Photonic Technology, Jena, Germany; Frank Garwe – Leibniz Institute of Photonic Technology, Jena, Germany; Domitille Schvartz – Department of Human Protein Sciences, Centre Médical Universitaire, Geneva, Switzerland; Jean-Charles Sanchez – Department of Human Protein Sciences, Centre Médical Universitaire, Geneva, Switzerland; Andreas Keller – Clinical Bioinformatics, University Hospital Saarland University, Saarbrücken, Germany; Joaquin Jurado Maqueda – Bioinf2Bio, Porto, Portugal. i3S-Instituto de Investigação e Inovação em Saúde Universidade do Porto, Porto, Portugal. Ipatimup-Institute of Molecular Pathology and Immunology University of Porto, Porto, Portugal.; Carla Oliveira – Bioinf2Bio, Porto, Portugal. i3S-Instituto de Investigação e Inovação em Saúde Universidade do Porto, Porto, Portugal. Ipatimup-Institute of Molecular Pathology and Immunology University of Porto, Porto, Portugal.; Irina Nazarenko – Institute for Infection Prevention and Hospital Epidemiology; Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany
Wednesday, Jul 22
12:14 PM – 12:29 PM

IntroductionKenneth Witwer – Department of Molecular and Comparative Pathobiology and Department of Neurology, The Johns Hopkins University School of Medicine
Wednesday, Jul 22
12:15 PM – 12:30 PM

Genetically encoded probes provide insight into extracellular vesicle cargo release in cellsBhagyashree Joshi – University Medical Center Groningen; Marit de Beer – Postdoctoral researcher; Ben N G Giepmans – Associate Professor; Inge S Zuhorn – Associate Professor
Wednesday, Jul 22
1:18 PM – 1:28 PM

EV complexity and heterogeneityEdit Buzás – Semmelweis University, Department of Genetics, Cell and Immunobiology, MTA-SE Immune-Proteogenomics Extracellular Vesicle Research Group, Budapest, Hungary and HCEMM_SE Extracellular Vesicle Research Group
Wednesday, Jul 22
1:28 PM – 1:38 PM

EV biogenesis and releasePascale Zimmermann – Cancer Research Center of Marseille
Wednesday, Jul 22
1:38 PM – 1:48 PM

EV uptake and fusionDavid R F. Carter – Oxford Brookes University
Wednesday, Jul 22
4:05 PM – 4:14 PM

Extracellular biogenesis of extravesicular rRNA- and tRNA-derived fragmentsJuan P. Tosar, PhD – Universidad de la República, Uruguay
Clinical/Translational
On Demand

OT01.5 - Comparative evaluation of EV isolation methods for EV subpopulation analysis in human urine, plasma and cell culture mediaLiang Dong, MD – The Brady Urological Institute, Johns Hopkins University School of Medicine; Richard Zieren, MD – The Brady Urological Institute, Johns Hopkins University School of Medicine; Kengo Horie, MD, PhD – The Brady Urological Institute, Johns Hopkins University School of Medicine; Sarah Amend – The Brady Urological Institute, Johns Hopkins University School of Medicine; Kenneth Pienta – The Brady Urological Institute, Johns Hopkins University School of Medicine
On Demand

OT01.6 - A Capillary-Channeled Polymer (C-CP) Fiber Spin-Down Tip Approach for the Isolation and Biomarker Characterization of Extracellular Vesicles of Ovarian Cancer OriginKaylan K. Jackson – Clemson University; Rhonda R. Powell – Clemson University; Terri F. Bruce, MDPhD – Clemson University; R. Kenneth Marcus – Clemson University
On Demand

OT01.8 - Use of an alternating current electrokinetic microelectrode chip to positively identify oncology, neurology, and infectious disease samples through plasma extracellular vesicle analysisRajaram Krishnan, PhD – Biological Dynamics, Inc.; Jean Lewis, MD PhD – Biological Dynamics, Inc.; David Searson – Biological Dynamics, Inc.; Orlando Perrera – Biological Dynamics, Inc.; Alfred Kinana, MD PhD – Biological Dynamics, Inc.; Heath Balcer, MD PhD – Biological Dynamics, Inc.; Rajaram Krishnan, PhD – Biological Dynamics, Inc.
On Demand

OT02.1 - Identification of critical modifying factors in EV-based communication between colorectal cancer and stromal cells using the organoid modelZsuzsanna Szvicsek – Semmelweis University, Department of Genetics, Cell and Immunobiology, Molecular Cancer Research Group, Budapest, Hungary; Adam Oszvald – Semmelweis University, Department of Genetics, Cell and Immunobiology; Anikó Zeöld – Semmelweis University, Department of Genetics, Cell and Immunobiology, Molecular Cancer Research Group, Budapest, Hungary; Andrea Kelemen – Semmelweis University, Department of Genetics, Cell and Immunobiology, Molecular Cancer Research Group, Budapest, Hungary; Tamás Tölgyes – Uzsoki Hospital, Budapest, Hungary; Kristóf Dede – Uzsoki Hospital, Budapest, Hungary; Attila Bursics – Uzsoki Hospital, Budapest, Hungary; Edit Buzás – Semmelweis University, Department of Genetics, Cell and Immunobiology, MTA-SE Immune-Proteogenomics Extracellular Vesicle Research Group, Budapest, Hungary and HCEMM_SE Extracellular Vesicle Research Group; Zoltán Wiener, PhD – Semmelweis University, Department of Genetics, Cell and Immunobiology, Molecular Cancer Research Group, Budapest, Hungary
On Demand

OT02.2 - Prostate Cancer-derived EVs Induce a Pro-inflammatory Phenotype in the StromaBlandine F. Victor, MS – Cedars-Sinai Medical Center; Dolores Di Vizio – Cedars-Sinai Medical Center; Andrew Chin – Cedars-Sinai; Tatyana Vagner, PhD – Cedars-Sinai Medical Center; Javier Mariscal – Cedars-Sinai Medical Center; Mandana Zandian – Cedars-Sinai Medical Center; Catherine Grasso – Cedars-Sinai Medical Center; Roberta Gottlieb – Cedars-Sinai Medical Center; Helen Goodridge – Cedars-Sinai Medical Center
On Demand

OT02.3 - The αvβ6 integrin in cancer cell-derived small extracellular vesicles enhances angiogenesisShiv Ram Krishn, PhD – Thomas Jefferson University, Philadelphia, USA; Israa Salem – Thomas Jefferson University; Fabio Quaglia, PhD – Thomas Jefferson University; Nicole M. Naranjo – Thomas Jefferson University; Ekta Agarwal – The Wistar Institute; Peter A. McCue – Thomas Jefferson University; Paul H. Weinreb – Biogen Inc.; Shelia M. Violette – Biogen; Dario C. Altieri – Immunology, Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, PA 19104 USA; Lucia R. R. Languino, PhD – Department of Cancer Biology, Thomas Jefferson University
On Demand

OT02.4 - Prostate cancer exosomes promote bone metastasis in a cholesterol-dependent mannerStephen E. Henrich – Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611; Kaylin McMahon – Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611; Michael Plebanek – Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611; Fabio Tavora – Brown University, Providence, RI, 02912; Andre De Souza – Lifespan Cancer Institute, Providence, RI, 02903; Anthony Mega – Lifespan Cancer Institute, Providence, RI, 02903; Benedito Carneiro – Brown University, Providence, RI, 02912; Colby Thaxton – Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611; Simpson Querrey Institute for BioNanotechnology, Northwestern University, Chicago, IL, 60611; Robert H. Lurie Comprehensive Cancer Center Northwestern University, Chicago IL, 60611
On Demand

OT02.5 - Low aggressive HNSCC-derived EVs regulates metastatic potential of highly metastasized HNSCC.Shinya Sato, MD, PhD – Division of Molecular Pathology and Genetics, Kanagawa Cancer Center Research Institute; Michael Korrer – Department of Otolaryngology, Vanderbilt University Medical Center; Sohini Roy – Department of Otolaryngology, Vanderbilt University Medical Center; Young Kim – Department of Otolaryngology, Vanderbilt University Medical Center; Alissa Weaver – Department of Cell and Developmental Biology, Vanderbilt University School of Medicine
On Demand

OT02.6 - Desmoglein 2 enhances squamous cell carcinoma tumor development through extracellular vesicles in an IL-8/miR-146a-dependent mechanismJoseph P. Flemming – Thomas Jefferson University; Mohammed Haque – Thomas Jefferson University; Brianna L. Hill – Thomas Jefferson University; James Wahl – UNMC; Kenneth Tsai – Moffitt Cancer Center; Peter Wermuth – TJU; Andrew Overmiller – Thomas Jefferson University; My Mahoney – Thomas Jefferson University
On Demand

OT03.3 - Hypoxia enhances the therapeutic potential of human CD34+ stem cell exosomes in ischemic hindlimb repairShweta Lodha, BA – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Morad Asadi – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Susmita Sahoo – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Marta Adamiak, PhD – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Cherrie Sherman – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Douglas Losardo – Feinberg Cardiovascular Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, IL; Rajesh Gupta – University of Toledo; Luca Musante – University of Virginia School of Medicine; Uta Erdbrügger – University of Virginia; Michael Davis – Emory University; David Kim – Feinberg Cardiovascular Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, IL
On Demand

OT03.4 - MiRNA-192 and -432 depleted c-kit+ progenitor cell exosomes promotes the proliferation, migration of mesenchymal stem cells and regulates inflammationHyun-Ji Park, PhD – Emory University; Jessica R. Hoffman – Emory University; Michael Davis – Emory University
On Demand

OT04.1 - Endo-lysosomes as an alternative intracellular location for EV cargo delivery with disease relevanceGiona Pedrioli, MSc – Laboratory for Biomedical Neurosciences, LBN-EOC; Marialuisa Barberis – Laboratory for Biomedical Neurosciences, LBN-EOC; Diego Morone – Istituto di Ricerca in Biomedicina; Paolo Paganetti – Laboratory for Biomedical Neurosciences, LBN-EOC
On Demand

OT04.3 - Anti-human Fab fragment of CD9 antibody prevents the endocytosis of melanoma and colon cancer-derived extracellular membrane vesicles and nuclear transfer of their cargosAurelio Lorico, MD, PhD – Touro University Nevada College of Medicine; Mark Santos – Touro University College of Medicine; Jana Karbanová – Technische Universität Dresden; Kevin Huang – Touro University Nevada College of Medicine; Tony Huynh – Touro University Nevada College of Medicine; Gyunghwi Woo – Touro University Nevada College of Medicine; Cheryl Vanier – Touro University Nevada; Chikao Morimoto – Juntendo University; Germana Rappa – Touro University Nevada College of Medicine; Denis Corbeil – Tissue Engineering Laboratories, Technische Universität Dresden,; Aurelio Lorico, MD, PhD – Touro University Nevada College of Medicine
On Demand

OT06.1 - Regulation of liver homeostasis, regeneration and diseases by mesenchymal stem cell-derived apoptotic extracellular vesiclesBingdong Sui – University of Pennsylvania
On Demand

OT06.2 - MSC-sEVs restore structural and mechanical properties in a rabbit model of cartilage injuryWei seong Toh, PhD – Faculty of Dentistry, National University of Singapore, Singapore. Department of Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore. Tissue Engineering Program, Life Sciences Institute, National University of Singapore, Singapore. Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore; Wei seong Toh, PhD – Faculty of Dentistry, National University of Singapore, Singapore. Department of Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore. Tissue Engineering Program, Life Sciences Institute, National University of Singapore, Singapore. Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore; Shipin zhang, MD PhD – Faculty of Dentistry, National University of Singapore, Singapore. Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Francis Keng lin Wong, MCI, F.R.C.S., F.A.M.S. – Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Department of Orthopaedic Surgery, Sengkang General Hospital, Singhealth, Singapore; Barry Wei Loong Tan, MBBS – Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; James Hoi Po Hui, F.R.C.S., F.A.M.S., M.D. – Tissue Engineering Program, Life Sciences Institute, National University of Singapore, Singapore. Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Sai Kiang Lim, MDPhD – Institute of Medical Biology, Agency for Science, Technology and Research, Singapore. Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Sai Kiang Lim, MDPhD – Institute of Medical Biology, Agency for Science, Technology and Research, Singapore. Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
On Demand

OT06.3 - Mesenchymal Stromal Cell Exosomes Educate Myeloid Cell Populations to Alleviate Neonatal Hyperoxia-Induced Lung InjuryGareth R. Willis, PhD – Harvard University & Boston Children's Hospital; Monica Reis – Harvard University & Boston Children's Hospital; Angeles Fernandez-Gonzalez – Harvard University & Boston Children's Hospital; Vincent Yeung – Harvard University & Boston Children's Hospital; Xianlan Liu – Boston Children's Hospital; S Alex Mitsialis – Harvard University & Boston Children's Hospital; Stella Kourembanas – Harvard University & Boston Children's Hospital
On Demand

OT06.4 - Immunomodulatory small extracellular vesicles derived from mesenchymal stem cells: A potential cell-free therapy for acute and chronic pulmonary vascular diseasesAlvin Tieu, BMSc, MSc – Clinical Epidemiology Program and Regenerative Medicine Program, Ottawa Hospital Research Institute; Casey Lansdell, MSc – Regenerative Medicine Program, Ottawa Hospital Research Institute; Duncan Stewart, MD – Ottawa Hospital Research Institute; Dylan Burger, PhD – Chronic Disease Program, Ottawa Hospital Research Institute; Manoj Lalu, MD, MDPhD – Clinical Epidemiology Program, Ottawa Hospital Research Institute
On Demand

OT06.6 - Changes in extracellular vesicle protein cargo after pro-inflammatory priming of umbilical cord mesenchymal stem cellsMairead Hyland, MSc Stem Cells and Regenerative Medicine – Keele University; Emma Wilson – University of Chester; Aled Clayton – Cardiff University; Claire Mennan – Keele University and RJAH Oswestry; Oksana Kehoe – Keele University
On Demand

OT07.1 - Alzheimer's disease biomarkers in plasma extracellular vesicles of neuronal origin correlate with brain pathology in miceFrancheska Delgado-Peraza – Laboratory of Clinical Investigation, National Institutes of Aging; Erez Eitan – NeuroDex; Carlos J. Nogueras-Ortiz, PhD – Laboratory of Clinical Investigation, National Institutes of Aging; Dong Liu – Department of otorhinolaryngology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University; Mark P Mattson – Johns Hopkins School of Medicine; Nigel Greig – National Institute on Aging/National Institutes of Health; Dimitrios Kapogiannis – Laboratory of Clinical Investigation, National Institutes of Aging
On Demand

OT07.2 - Exosomal ceramide mediates neurotoxicity of Amyloid beta (Aβ) in Alzheimer’s disease.Ahmed Elsherbini – University of Kentucky; Simone Crivelli – University of Kentucky; Alexander Kirov – Augusta University; Michael Dinkins – Augusta University; Zhihui Zhu – University of Kentucky; Haiyan Qin – University of Kentucky; Sanjib Karki – University of Kentucky; Priyanka Tripathi – University of Kentucky; Erhard Bieberich – University of Kentucky
On Demand

OT07.4 - Blood-derived extracellular vesicles in Multiple Sclerosis: the effects of Particulate Matter exposureLuca Ferrari, PhD – EPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano; Mirjam Hoxha – Epiget Lab Dipartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy; Simona Iodice – EPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano; Federica Rota – Epiget Lab Dipartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy; Jacopo Mariani, BS – EPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano; Giulia Mallucci – IRCCS Fondazione Mondino, Department of Neurology and Neurorehabilitation, Multiple Sclerosis Unit, Pavia, Italy; Roberto Bergamaschi – IRCCS Fondazione Mondino, Department of Neurology and Neurorehabilitation, Multiple Sclerosis Unit, Pavia, Italy; Valentina Bollati – EPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano
On Demand

OT07.6 - Plasma neuronal and astrocyte-derived exosomes serve as biomarkers of neurodegeneration and systemic bioenergetic effects in male Cynomolgus monkeys self-administrating oxycodoneAshish Kumar – Wake Forest Baptist Medical Center; Yixin Su – Wake Forest Baptist Medical Center; David Soto-Pantoja – Wake Forest Baptist Medical Center; Jingyun Lee – Wake Forest Baptist Medical Center; Ravi Singh – Wake Forest Baptist Medical Center; Cristina Furdui – Wake Forest Baptist Medical Center; Michael Nader – Wake Forest Baptist Medical Center; Gagan Deep, PhD – Wake Forest Baptist Medical Center; Gagan Deep, PhD – Wake Forest Baptist Medical Center
On Demand

OT08.2 - Vesicles released during Mycobacterium tuberculosis infection: immunomodulatory (glyco)lipids and role in host-pathogen interactionsEmilie Layre – CNRS-Université Paul Sabatier; Emilie Layre – CNRS-Université Paul Sabatier; Pierre Boyer – CNRS-Université Paul Sabatier; Jerome Nigou – CNRS-Université Paul Sabatier
On Demand

OT08.3 - Blood-Based Detection of Tuberculosis using Outer Membrane VesiclesNishal Shah, MS – University of Pennsylvania; Jina Ko, PhD – Massachusetts General Hospital, Wyss Institute at Harvard University; takahiro Yano – University of Pennsylvania; Sruthi Ravimohan – University of Pennsylvania; Greg Bisson – University of Pennsylvania; Harvey Rubin – University of Pennsylvania; David Issadore, MDPhD – Department of Bioengineering, University of Pennsylvania
On Demand

OT08.4 - Mechanisms of innate immune regulation by exosomes released during infection with pathogenic gram-negative bacteriaAdam Fleming – George Mason University; Heather Hobbs – George Mason University; Graham Matulis – George Mason University; Valentin Giroux – George Mason University; Weidong Zhou – Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA; Valerie Calvert – George Mason University; Carolina Salvador-Morales – George Mason University; Nitin Agrawal – Children's National Hospital; Emanuel Petricoin – George Mason University; Rekha Panchal – USAMRIID; Sina Bavari – USAMRIID; Ramin M. Hakami – George Mason University; Ramin M. Hakami – George Mason University
On Demand

OT08.6 - Human pathogenic fungus Candida albicans induces immunomodulatory TGF-β1-transporting vesicles from human immune cellsLuke D. Halder – Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (HKI); Emeraldo Jo – Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (HKI); Mohammad Hasan – Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (HKI); Marta Ferreira-Gomes – Friedrich Schiller University; Thomas Krüger – Leibniz Institute for Natural Product Research and Infection Biology (HKI), Department of Molecular and Applied Microbiology, Jena, Germany; Martin Westermann – University Hospital Jena; Diana Palme – Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (HKI); Günter Rambach – Medical University of Innsbruck; Niklas Beyersdorf – University of Würzburg; Cornelia Speth – Medical University of Innsbruck; Ilse Jacobsen – Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (HKI); Olaf Kniemeyer – Leibniz Institute for Natural Product Research and Infection Biology (HKI), Department of Molecular and Applied Microbiology, Jena, Germany; Berit Jungnickel – Friedrich Schiller University; Peter Zipfel – Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (HKI); Christine Skerka – Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (HKI)
On Demand

OT10.1 - Intranasal administration of neural stem cells-derived extracellular vesicles promotes neurogenesis and reduces neuroinflammation and amyloid plaques in a mouse model of Alzheimer’s diseaseLeelavathi N. Madhu – Institute of Regenerative medicine, College of Medicine, Texas A&M University; Raghavendra Upadhya, PhD – Institute of Regenerative Medicine, College of Medicine, Texas A&M University; Sahithi Attaluri, M Pharm – Institute of Regenerative Medicine, College of Medicine, Texas A&M University; Maheedhar Kodali, PhD – Institute for Regenerative Medicine, College of Medicine, Texas A&M University; Laila Melissari – Institute for Regenerative Medicine, College of Medicine, Texas A&M University; Andrew Vogel – Institute of Regenerative Medicine, College of Medicine, Texas A&M University; Bing Shuai – Institute of Regenerative Medicine, College of Medicine, Texas A&M University; Ashok K Shetty – Institute of Regenerative Medicine, College of Medicine, Texas A&M University
On Demand

OT10.2 - Protective effects of extracellular vesicles derived from induced pluripotent stem cells in acute kidney injury modelRafael S. Lindoso, PhD – Federal University of Rio de Janeiro; Rafael S. Lindoso, PhD – Federal University of Rio de Janeiro; Federica Collino, PhD – Pediatric Nephrology, Dialysis and Transplant Unit, Fondazione Ca' Granda IRCCS Ospedale Maggiore Policlinico of Milan; Jarlene Alécia Lopes – Federal University of Rio de Janeiro; Marta Tapparo – Department of Medical Sciences, Molecular Biotechnology Center, University of Torino; Giovane Tortelote – Department of Pediatrics' Section of Pediatric Nephrology, Tulane University School of Medicine; Taís Kasai-Brunswick – Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro; Gustavo Lopes – Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro; Douglas Barroso – Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro; Renata Skovronova – Department of Molecular Biotechnology and Health Sciences, University of Torino; Camila Wendt – Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro; Kildare Miranda – Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro; Benedetta Bussolati, MD, PhD – University of Torino; Adalberto Vieyra – Federal University of Rio de Janeiro
On Demand

OT10.4 - Epigenetic regulation of fetal hypoplastic lungs by amniotic fluid stem cell derived extracellular vesiclesLina Antounians, MSc – The Hospital for Sick Children; Huayun Hou – The Hospital for Sick Children; Cadia Chan – The Hospital for Sick Children; Michael Wilson – The Hospital for Sick Children; Augusto Zani – The Hospital for Sick Children; Augusto Zani – The Hospital for Sick Children
On Demand

OT10.5 - Bottom-up assembly of fully-synthetic extracellular vesiclesOskar Staufer, MA – Max Planck Institute for Medical Research, Department for Cellular Biophysics, Jahnstraße 29, 69120 Heidelberg, Germany; Oskar Staufer, MA – Max Planck Institute for Medical Research, Department for Cellular Biophysics, Jahnstraße 29, 69120 Heidelberg, Germany; Franziska Dietrich – Max Planck Institute for Medical Research, Department for Cellular Biophysics, Jahnstraße 29, 69120 Heidelberg, Germany; Jochen Hernandez – Max Planck Institute for Medical Research, Department for Cellular Biophysics, Jahnstraße 29, 69120 Heidelberg, Germany; Martin Schröter – Max Planck Institute for Medical Research, Department for Cellular Biophysics, Jahnstraße 29, 69120 Heidelberg, Germany; Sebastian Fabritz – Department for Chemical Biology, Max Planck Institute for Medical Research, Jahnstraße 29, 69120 Heidelberg, Germany; Heike Böhm – Max Planck Institute for Medical Research, Department for Cellular Biophysics, Jahnstraße 29, 69120 Heidelberg, Germany; Ilia Platzman – Max Planck Institute for Medical Research, Department for Cellular Biophysics, Jahnstraße 29, 69120 Heidelberg, Germany; Joachim Spatz – Max Planck Institute for Medical Research, Department for Cellular Biophysics, Jahnstraße 29, 69120 Heidelberg, Germany
On Demand

OT11.1 - Unbiased quantitative proteomic analysis identifies novel cellular components specifically incorporated into endogenous EV subtypes, HIV-1 particles and virus-modified EVslorena Martin-Jaular – INSERM U932, Institut Curie, PSL Research university; Nathalie Nevo – INSERM U932, Institut Curie, PSL Research university; mercedes tkach – INSERM U932, Institut Curie, PSL Research university; mabel jouve – CNRS UMR3215, Institut Curie, PSL Research university; Florent Dingli – Institut Curie, PSL Research University, Laboratoire de Spectrométrie de Masse Protéomique; damarys loew – Institut Curie, PSL Research University, Laboratoire de Spectrométrie de Masse Protéomique; Kenneth Witwer – Department of Molecular and Comparative Pathobiology and Department of Neurology, The Johns Hopkins University School of Medicine; matias ostrowski – Instituto INBIRS, Universidad de Buenos Aires-CONICET; georg borner – Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry,; Clotilde Théry, MD PhD – INSERM U932, Institut Curie, PSL Research university; lorena Martin-Jaular – INSERM U932, Institut Curie, PSL Research university
On Demand

OT11.2 - The encephalomyocarditis virus Leader modulates autophagic pathways to promote the release of virions inside extracellular vesiclesKyra AY Defourny, Msc – Dept. Biomolecular Health Sciences, Fac. Veterinary Medicine, Utrecht University, The Netherlands; Susanne G. Van der grein – Dept. Biomolecular Health Sciences, Fac. Veterinary Medicine, Utrecht University, The Netherlands; Huib rabouw – Dept. Biomolecular Health Sciences, Fac. Veterinary Medicine, Utrecht University, The Netherlands; Frank J.M. Van Kuppeveld – Dept. Biomolecular Health Sciences, Fac. Veterinary Medicine, Utrecht University, The Netherlands; Esther Nolte-'t Hoen – Dept. Biomolecular Health Sciences, Fac. Veterinary Medicine, Utrecht University
On Demand

OT11.3 - ZIKV induced DEFA1B blocks ZIKV adsorption and retard cell cycle by regulating ORC1 expressionShuang Li – Institute of Blood Transfusion, Peking Union Medical College; Shilin Li – Institute of Blood Transfusion, Chinese Academy of Medical Sciences Peking Union Medical College; Limin Chen – Institute of Blood Transfusion, Chinese Academy of Medical Sciences Peking Union Medical College
On Demand

OT11.4 - Extracellular vesicles mediate bacterial-immune cell interactions during respiratory viral-bacterial co-infectionsSidney Lane – University of Pittsburgh; Matthew Hendricks – University of Washington; Jennifer Bomberger – University of Pittsburgh
On Demand

OT11.5 - Using machine learning with neuronal EV target proteins and clinical data to predict cognitive impairment in HIV infectionLynn Pulliam, PhD – University of California, San Francisco; Michael Liston, MS – Veteran Affairs; bing Sun, M.D., MD PhD – NCIRE; Jared Narvid – UCSF
On Demand

OF12.1 - Development of non-invasive clinically applicable in vivo tracking of extracellular vesicles using magnetic resonance imaging (MRI)Johnny Akers – Visicell Medical; Paola Aguiari – Children's Hospital Los Angeles; Hamsik Soloyan – Children's Hospital Los Angeles; Seda Mkhitaryan – Children's Hospital Los Angeles; Gevorg Karapetyan – Children's Hospital Los Angeles; Laura Perin – Children's Hospital Los Angeles-University of Southern California; Mya Thu – Children's Hospital Los Angeles-University of Southern California; Sargis Sedrakyan, PhD – Children's Hospital Los Angeles-University of Southern California; Sargis Sedrakyan, PhD – Children's Hospital Los Angeles-University of Southern California
On Demand

OF12.4 - Dietary cross-species communication: context-dependent role of bovine extracellular vesicles in cancer progressionRahul Sanwlani, MSc – La Trobe Institute for Molecular Sciences, La Trobe University, Melbourne, Australia; Monisha Samuel – La Trobe Institute for Molecular Sciences, La Trobe University, Melbourne, Australia; Suresh Mathivanan – La Trobe University
On Demand

OF14.1 - Extracellular vesicles - a tattletale for rare gene editing eventsKoen Breyne, PhD – MGH-Harvard Medical School; Stefano Ughetto – MGH-Harvard Medical School; Xandra O Breakefield – MGH-Harvard Medical school
On Demand

OF14.2 - Y-RNA subtype ratios in plasma extracellular vesicles are cell type specific and are candidate biomarkers for inflammatory diseasesTom Driedonks, PhD – Dept. Molecular & Comparative Pathobiology, Johns Hopkins School of Medicine; Sanne Mol – Dept. Biochemistry & Cell Biology, Fac. Veterinary Medicine, Utrecht University, The Netherlands; Sanne de Bruin – Dept. Intensive Care, Amsterdam University Medical Centers, location AMC, Amsterdam, The Netherlands; Anna-Linda Peters – Dept. Anesthesiology, University Medical Center Utrecht, Utrecht, The Netherlands; Xiaogang Zhang – Dept. Biochemistry & Cell Biology, Fac. Veterinary Medicine, Utrecht University, The Netherlands; Marthe Lindenbergh – Dept. Biochemistry & Cell Biology, Fac. Veterinary Medicine, Utrecht University, The Netherlands; Boukje Beuger – Dept. of Blood Cell Research, Sanquin Research, and Landsteiner Laboratory, Amsterdam University Medical Centers, Location AMC, Amsterdam, The Netherlands; Anne-Marieke Stalborch – Molecular Cell Biology lab, Dept. of Molecular and Cellular Hemostasis, Sanquin Research, and Landsteiner Laboratory, Amsterdam University Medical Centers, Location AMC, Amsterdam, The Netherlands; Thom Spaan – Dept. of Infectious Diseases & Immunity, Division of Virology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands; Esther de Jong – Dept. Experimental Immunology, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, The Netherlands; Erhard van der Vries – Dept. of Infectious Diseases & Immunity, Division of Virology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands; Coert Margadant – Molecular Cell Biology lab, Dept. of Molecular and Cellular Hemostasis, Sanquin Research, and Landsteiner Laboratory, Amsterdam University Medical Centers, Location AMC, Amsterdam, The Netherlands; Robin van Bruggen – Dept. of Blood Cell Research, Sanquin Research, and Landsteiner Laboratory, Amsterdam University Medical Centers, Location AMC, Amsterdam, The Netherlands; Alexander Vlaar – Dept. Intensive Care, Amsterdam University Medical Centers, location AMC, Amsterdam, The Netherlands; Tom Groot Kormelink – Dept. Experimental Immunology, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, The Netherlands; Esther Nolte-'t Hoen – Dept. Biomolecular Health Sciences, Fac. Veterinary Medicine, Utrecht University
On Demand

OF14.6 - Urinary extracellular vesicles transcriptome in diabetic kidney diseaseOm Dwivedi – Institute for Molecular Medicine Finland FIMM, University of Helsinki, Finland; Maija Puhka – Institute for Molecular Medicine Finland FIMM, University of Helsinki, Finland; Karina A. Barreiro, MSc – Institute for Molecular Medicine Finland FIMM, University of Helsinki, Finland; erkka valo – Folkhälsan Institute of Genetics, Folkhälsan Research Center, Helsinki, Finland; Harry Holthofer – Institute for Molecular Medicine Finland FIMM, University of Helsinki, Finland; per-henrik Groop – Abdominal Center Nephrology, University of Helsinki and Helsinki University Hospital, Finland; Carol Forsblom – Folkhälsan Institute of Genetics, Folkhälsan Research Center, Helsinki, Finland; tiinamaija tuomi – Hospital District of Helsinki and Uusimaa (HUS), Helsinki, Finland; Leif Groop – Institute for Molecular Medicine Finland FIMM, University of Helsinki, Finland
On Demand

OF15.1 - Engineering extracellular vesicles for targeted delivery of Cas9 to T cellsDevin M. Stranford – Northwestern University; Lacy Simons – Northwestern University; Judd F. Hultquist – Northwestern University; Joshua N. Leonard – Northwestern University
On Demand

OF15.2 - Exosomal AAVs in Myocardial Repair: Escaping Neutralizing Antibody and Enhancing DeliveryMarta Adamiak, PhD – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Shweta Lodha, BA – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Morad Asadi – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Yaxuan Liang – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Cherrie Sherman – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Erik Kohlbrenner – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Dongtak Jeong – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Delaine Ceholski – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Navneet Dogra, PhD – Department of Genetics and Genomic Sciences, Department of Pathology, Icahn School of Medicine, Mount Sinai; Nicole Dubois – Department of Developmental and Regenerative Biology, Mindich Child Health and Development Institute, Black Family Stem Cell Institute, Icahn School of Medicine, Mount Sinai; Roger Hajjar – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Susmita Sahoo – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai
On Demand

OF15.3 - Computational Modeling of Mesenchymal Stem Cell Exosomes Predicts Cardiac Improvements in Preclinical and Clinical Models of Hypoplastic Left Heart SyndromeJessica R. Hoffman – Emory University; Laxminarayana Korutla – University of Pennsylvania; Mohamed Abdullah – University of Maryland School of Medicine; Gregory Bittle – University of Maryland School of Medicine; Joshua Hare – University of Miami; Joey Harmon – University of Pennsylvania; Robert Hu – University of Pennsylvania; Rachana Mishra – University of Maryland School of Medicine; David Morales – University of Maryland School of Medicine; Sudhish Sharma – University of Maryland School of Medicine; Sunjay Kaushal – University of Maryland School of Medicine; Prashanth Vallabhajosyula – Yale University; Michael Davis – Emory University
On Demand

OF15.6 - RNA nanoparticles as EV displaying ligands for specific cancer targeting and efficient RNAi delivery in vivoZhefeng Li, PhD – College of Pharmacy, The Ohio State University; Fengmei Pi, PhD – ExonanoRNA; Zhen Zheng – Center for RNA Nanobiotechnology and Nanomedicine; College of Pharmacy; Comprehensive Cancer Center; Dorothy M. Davis Heart and Lung Research Institute; College of Medicine. The Ohio State University; Peixuan Guo – Center for RNA Nanobiotechnology and Nanomedicine; College of Pharmacy; Comprehensive Cancer Center; Dorothy M. Davis Heart and Lung Research Institute; College of Medicine. The Ohio State University
On Demand

OF16.1 - Multiplex Nanoscale Flow Cytometry to Study the Circulating Extracellular Vesicle Biome in Patients with Pancreatic Cancer versus Screen Negative ControlsMayu Morita – OHSU; Thuy Ngo – Knight CEDAR Technology, OHSU; Emek Demir – OHSU; Randall Armstrong – OHSU; Scott Bornheimer – BD Biosciences; Terry K. Morgan, MD, PHD – OHSU; Terry K. Morgan, MD, PHD – OHSU
On Demand

OF16.2 - Analysis of surface markers as biomarkers for small cell lung cancerPatricia Midori M. M. Murobushi Ozawa, PhD – Department of Cell and Developmental Biology, Vanderbilt University School of Medicine; Sarah M. Groves – Department of Biochemistry, Vanderbilt University Medical Center; Vito Quaranta – Department of Biochemistry, Vanderbilt University Medical Center; Alissa Weaver – Department of Cell and Developmental Biology, Vanderbilt University School of Medicine
On Demand

OF16.3 - Leukobiopsy – exploiting extracellular vesicle-mediated leukocyte sequestration of cancer-specific signaturesJanusz Rak, MD, PhD – McGill University; Janusz Rak, MD, PhD – McGill University; Shipa Chennakrishnaiah – McGill University; Laura Montermini – RIMUHC; Brian Meehan – RIMUHC; Thupten Tsering – RIMUHC; Saro Aprikian – McGill University; Dongsic Choi – RIMUHC
On Demand

OF16.4 - Whole-Transcriptomic Profiling of Circulating Small Extracellular Vesicles Derived RNAs for Early Detection of Colorectal Carcinoma and AdenomaLi Min, PhD – Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.; Shengtao Zhu – Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.; Xiang Liu – Echo Biotech Co., Ltd, Beijing, China.; Da Qin – Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.; Qingdong Guo – Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.; Rui Wei – Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.; Libo Zhao – Echo Biotech Co., Ltd, Beijing, China.; Guanyi Kong – Echo Biotech Co., Ltd, Beijing, China.; Shutian Zhang – Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.; Shutian Zhang – Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.
On Demand

OF16.5 - RNA Signatures from Blood and Urine EVs Display Tissue-Lineage from Prostate Cancer PatientsNavneet Dogra, PhD – Department of Genetics and Genomic Sciences, Department of Pathology, Icahn School of Medicine, Mount Sinai; Navneet Dogra, PhD – Department of Genetics and Genomic Sciences, Department of Pathology, Icahn School of Medicine, Mount Sinai; Mehmet Ahsen – Icahn School of Medicine at Mount Sinai; Tina Chen – Icahn School of Medicine at Mount Sinai; Reena Olsen – Icahn School of Medicine at Mount Sinai; Dan Han – Icahn School of Medicine at Mount Sinai; Stacey M. Gifford – IBM; Benjamin Wunsch – IBM; Rachel Weil – Icahn School of Medicine at Mount Sinai; Melissa Smith – Icahn School of Medicine at Mount Sinai; Joshua Smith – IBM; Sungchel Kim – IBM; Kamala Bhatt – Icahn School of Medicine at Mount Sinai; Sujit Nair – Icahn School of Medicine at Mount Sinai; Bojan Losic, MDPhD – Icahn School of Medicine at Mount Sinai; Robert Sebra – Icahn School of Medicine at Mount Sinai; Adam Margolin – Icahn School of Medicine at Mount Sinai; Carlos Cordon-Cardo – Icahn School of Medicine at Mount Sinai; Ashutosh Tewari – Icahn School of Medicine at Mount Sinai; GUSTAVO Stolovitzky – Icahn School of Medicine at Mount Sinai
On Demand

OF16.6 - A multi-model, liquid biopsy approach for diagnosing and staging pancreatic adenocarcinomaZijian Yang, MS – University of Pennsylvania; Michael LaRiviere – University of Pennsylvania; Jina Ko, PhD – Massachusetts General Hospital, Wyss Institute at Harvard University; Jacob Till – University of Pennsylvania; Theresa Christensen – University of Pennsylvania; Stephanie Yee – University of Pennsylvania; Taylor Black – University of Pennsylvania; Kyle Tien – University of Pennsylvania; Andrew A. Lin – University of Pennsylvania; Hanfei Shen – University of Pennsylvania; Andrew Adallah – University of Pennsylvania; Mark O'Hara – University of Pennsylvania; Charles Vollmer – University of Pennsylvania; Bryson Katona – University of Pennsylvania; Ben Stanger – University of Pennsylvania; David Issadore, MDPhD – Department of Bioengineering, University of Pennsylvania; Erica Carpenter – University of Pennsylvania
On Demand

OF17.1 - The Proteome of Circulating Large EVs in Diabetes and HypertensionDylan Burger, PhD – Chronic Disease Program, Ottawa Hospital Research Institute; Dylan Burger, PhD – Chronic Disease Program, Ottawa Hospital Research Institute; Ozgun Varol – Ottawa Hospital Research Institute; Maddison Turner – Ottawa Hospital Research Institute; Christopher Kennedy – Ottawa Hospital Research Institute
On Demand

OF17.3 - Understanding the role of endothelial cell-derived apoptotic bodies in inflammatory signaling and cell clearance in an atherosclerosis model of inflammation.Amy A. Baxter, PhD – La Trobe University; Georgia Atkin-Smith – La Trobe University, Walter & Eliza Hall Institute for Medical Research; Stephanie Paone – St Pancras Clinical Research; Mark Hulett – La Trobe University; Ivan Poon – La Trobe University
On Demand

OF17.4 - Adipose mesenchymal stromal cell derived EVs foster cardio-renal protection in the DOCA-salt hypertensive rat modelRafael S. Lindoso, PhD – Federal University of Rio de Janeiro; Jarlene Alécia Lopes – Federal University of Rio de Janeiro; Renata Binato – National Institute of Cancer; Eliana Abdelhay – National Institute of Cancer; christina Moeda Takiya – Federal University of Rio de Janeiro; Giovanni Montini; Benedetta Bussolati, MD, PhD – University of Torino; Adalberto Vieyra – Federal University of Rio de Janeiro; Federica Collino, PhD – Pediatric Nephrology, Dialysis and Transplant Unit, Fondazione Ca' Granda IRCCS Ospedale Maggiore Policlinico of Milan; Federica Collino, PhD – Pediatric Nephrology, Dialysis and Transplant Unit, Fondazione Ca' Granda IRCCS Ospedale Maggiore Policlinico of Milan
On Demand

OS19.1 - Extracellular vesicle associated microRNA-29a elicits microglial activation and synaptodendritic injury with chronic methamphetamine exposureDalia Moore – University of Nebraska Medical Center; Alexander Clark – Creighton University; Farah Shahjin – UNMC; Niming Wu – University of Nebraska Medical Center; Subhash Chand – University of Nebraska Medical Center; katherine odegaard – University of Nebraska Medical Center; austin Gowen – University of Nebraska Medical Center; Rick Bevins, MDPhD – UNIVERSITY OF NEBRASKA AT LINCOLN; Gurudutt Pendyala, MDPhD – University of Nebraska Medical Center; Howard Fox, MDPHD – University of Nebraska Medical Center; Sowmya V. Yelamanchili, PhD – Department of Anesthesiology; Sowmya V. Yelamanchili, PhD – Department of Anesthesiology
On Demand

OS19.2 - Blood-borne and brain-derived ectosomes/microparticles in morphine-induced anti-nociceptive toleranceDeepa Ruhela, MD PhD – University of Maryland School of Medicine; Veena Bhopale, MD PhD – University of Maryland School of Medicine; Ming Yang, MD – University of Maryland School of Medicine; Kevin Yu, MD PhD – University of Maryland School of Medicine; Eric Weintraub, MD – University of Maryland School of Medicine; Aaron Greenblatt, MD – University of Maryland School of Medicine; Stephen R. Thom, MD, PhD – University of Maryland School of Medicine; Stephen R. Thom, MD, PhD – University of Maryland School of Medicine
On Demand

OS19.3 - EVs are a conveyor of toxic dipeptide repeat proteins in C9orf72 ALS/FTD modelsMaria Elena Cicardi – Thomas Jefferson University; Davide Trotti – Thomas jefferson University
On Demand

OS19.4 - Amniotic fluid stem cell derived extracellular vesicles modulate pathogenic immune responses in experimental autoimmune encephalomyelitisGiorgia Manni, PhD – Department of Experimental Medicine, Section of Pharmacology, University of Perugia; Rita Romani – Department of Experimental Medicine, Sec. Biology; Marco Gargaro – Department of Experimental Medicine, Sec Pharmacology; Luisa Pascucci – Department of Veterinary Medicine; Pierluigi Orvietani – Department of Experimental Medicine, Sec. Phisiolgy and Biochemistry; Paolo Puccetti – Department of Experimental Medicine, Sec. Pharmacology; Vincenzo Nicola Talesa – Department of Experimental Medicine, Sec. of Biology; Francesca Fallarino – Department of Experimental Medicine, Sec. of Pharmacology
On Demand

OS19.5 - Association of neuronal-derived extracellular vesicles cargo with cognitive decline in late middle lifeErden Eren, PhD – National Institute on Aging, NIH; Jack Hunt – Wisconsin Alzheimer’s Disease Research Center, University of Wisconsin; Michelle Shardell – University of Maryland; Sahil Chawla – National Institute on Aging, NIH; Joyce Tran – National Institute on Aging, NIH; Jeffrey Gu – NIA/NIH; Nick Vogt – Wisconsin Alzheimer’s Disease Research Center, University of Wisconsin; Sterling Johnson – Wisconsin Alzheimer’s Disease Research Center, University of Wisconsin; Barbara B. Bendlin – Wisconsin Alzheimer’s Disease Research Center, University of Wisconsin; Dimitrios Kapogiannis – Laboratory of Clinical Investigation, National Institutes of Aging
On Demand

OS19.6 - Extracellular Vesicle Release from the Choroid Plexus Visualized Using ExoMap-2 MiceChristie D. Fowler, PhD – University of California, Irvine; Valeria Lallai, MD PhD – University of California, Irvine; Francis Fordjour, MD PhD – Johns Hopkins University; Lane Christenson, MDPhD – University of Kansas Medical Center; Stephen Gould, MD PhD – Johns Hopkins University
On Demand

OS20.1 - Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signaling pathway in the recipient cellsPAMALI FONSEKA, PhD – La Trobe Institute for Molecular Sciences, La Trobe University; Hina Kalra – La Trobe University; Lahiru Gangoda – La Trobe University; Suresh Mathivanan – La Trobe University
On Demand

OS20.3 - Salivary exosomes – Carrier of High Risk Human Papillomavirus Causing Oropharyngeal Cancerchamindie punyadeera, PhD – QUT; chamindie punyadeera, PhD – QUT; kai tang – QUT; Liz Kenny – RBWH; Brett Hughes – RBWH; sarj vasani – RBWH; Yunxia Wan – QUT
On Demand

OS21.1 - Continuous in vivo release of mast cell derived extracellular vesicles from an implanted device spreads pro-inflammatory response in miceKrisztina V. Vukman, PhD – Dept. of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary; Gábor Seregélyes – 1Dept. of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary; Tamás Visnovitz – Dept. of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary; Péter Lőrincz – Department of Anatomy, Cell and Developmental Biology, Eötvös Loránd University, Budapest, Hungary; Anna Koncz – Dept. of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary; Andrea Ferencz – Department of Surgical Research and Techniques, Semmelweis University, Budapest, Hungary; Daniella Fehér – Department of Surgical Research and Techniques, Semmelweis University, Budapest, Hungary; Krisztina Juhos – Department of Surgical Research and Techniques, Semmelweis University, Budapest, Hungary; Barabara Sódar – Dept. of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary; Krisztina Pálóczi – Dept. of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary; Eszter Tóth – Dept. of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary; András Försönits – Dept. of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary; Delaram Khamari – Dept. of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary; Alicia Galinsoga – Dept. of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary; Edit Buzás – Semmelweis University, Department of Genetics, Cell and Immunobiology, MTA-SE Immune-Proteogenomics Extracellular Vesicle Research Group, Budapest, Hungary and HCEMM_SE Extracellular Vesicle Research Group
On Demand

OS21.2 - Small extracellular vesicles modulated by the αVβ3 integrin reprogram recipient cells towards an aggressive neuroendocrine cancer phenotypeFabio Quaglia, PhD – Thomas Jefferson University; Shiv Ram Krishn, PhD – Thomas Jefferson University, Philadelphia, USA; George Daaboul, MDPhD – NanoView Biosciences; Srawasti Sarke – Thomas Jefferson University; Peter A. McCue – Thomas Jefferson University; William Kelly – Thomas Jefferson University; Qin Liu – Wistar Institute; Lucia R. R. Languino, PhD – Department of Cancer Biology, Thomas Jefferson University
On Demand

OS21.6 - Astrocyte-derived EV-mediated blood-brain barrier disruptionShilpa Buch, PhD – University of Nebraska Medical Center; Ke Liao – University of Nebraska Medical Center; Susmita Sil – University of Nebraska Medical Center; Fang Niu – University of Nebraska Medical Center; Guoku Hu, PhD – University of Nebraska Medical Center
On Demand

OS22.2 - Extracellular vesicles containing host restrictive factor IFITM3 inhibited Zika virus infection of fetuses in pregnant mice through trans-placenta deliveryAllen Z. Wu, PhD – Nanjing University; Allen Z. Wu, PhD – Nanjing University
On Demand

OS22.3 - Engineering extracellular vesicles with altered cellular tropism for targeted payload delivery in vivoMonique Kauke, PhD – Codiak BioSciences; Nikki Ross – Codiak BioSciences; Dalia Burzyn – Codiak BioSciences; Shelly Martin – Codiak BioSciences; Ke Xu – Codiak BioSciences; Nuruddeen Lewis – Codiak BioSciences; Charan Leng – Codiak BioSciences; Su Chul Jang – Codiak BioSciences; Stephanie Yu – Codiak BioSciences; Kevin Dooley – Codiak BioSciences; Sriram Sathyanarayanan – Codiak BioSciences; Jonathan Finn – Codiak BioSciences
On Demand

OS22.4 - A novel method for the delivery of cell-free therapy to fetuses with congenital anomalies: a proof of principle studyLina Antounians, MSc – The Hospital for Sick Children; Lina Antounians, MSc – The Hospital for Sick Children; Louise Montalva – The Hospital for Sick Children; Gabriele Raffler – The Hospital for Sick Children; Maria Sole Gaffi – The Hospital for Sick Children; Augusto Zani – The Hospital for Sick Children; Augusto Zani – The Hospital for Sick Children
On Demand

OS22.5 - Microalgae as a novel and renewable bioresource of extracellular vesicleAntonella Bongiovanni, PhD – Institute for Research and Biomedical Innovation (IRIB) - National Research Council (CNR); Antonella Bongiovanni, PhD – Institute for Research and Biomedical Innovation (IRIB) - National Research Council (CNR); Giorgia Adamo – Institute for Research and Biomedical Innovation (IRIB) - National Research Council (CNR); Sabrina Picciotto – Institute for Research and Biomedical Innovation (IRIB) - National Research Council (CNR); University of Palermo; David Fierli – Institute of Technology Sligo (ITSligo); Maria Elena Barone – Institute of Technology Sligo (ITSligo); Anita Aranyos – Institute of Technology Sligo (ITSligo); Rachel Parkes – Institute of Technology Sligo (ITSligo); Svenja Morsbach – Max-Planck Institute for Polymer Research; Samuele Raccosta – Institute of Biophysics (IBF) - National Research Council (CNR); Darja Božič – University of Ljubljana; Antonella Cusimano – Institute for Research and Biomedical Innovation (IRIB) - National Research Council (CNR); Christopher Stanly – Institute of Biosciences and BioResources (IBBR) - National Research Council (CNR); Daniele P Romancino – Institute for Research and Biomedical Innovation (IRIB) - National Research Council (CNR); Rita Carrotta – Institute of Biophysics (IBF) - National Research Council (CNR); Carolina Paganini, MS – ETH Zurich; Umberto Capasso Palmiero – ETH Zurich; Vincenzo Martorana – Institute of Biophysics (IBF) - National Research Council (CNR); Rosina Noto – Institute of Biophysics (IBF) - National Research Council (CNR); Giovanna L Liguori – Institute of Genetics and Biophysics (IGB) - National Research Council (CNR); Annamaria Kisslinger – Institute of Experimental Endocrinology and Oncology (IEOS); Laura Corcuera – Zabala Innovation Consulting; Elia Di Schiavi – Institute of Biosciences and BioResources (IBBR) - National Research Council (CNR); Veronika Kralj-Iglič – University of Ljubljana; Ales Iglič – University of Ljubljana; Katharina Landfester – Max-Planck Institute for Polymer Research; Paolo Arosio – ETH Zurich; Gabriella Pocsfalvi – Institute of Biosciences and BioResources (IBBR) - National Research Council (CNR); Mauro Manno – Institute of Biophysics (IBF) - National Research Council (CNR); Nicolas Touzet – Institute of Technology Sligo (ITSligo)
On Demand

OS23.2 - Pro-inflammatory cytokine-mediated alterations in beta cell extracellular vesicle cargo and function enhance activation of the CXCL10-CXCR3 axis in diabetesNaureen Javeed, MSc, PhD – Department of Physiology and Biomedical Engineering, Mayo Clinic; Tracy Her – Department of Physiology and Biomedical Engineering, Mayo Clinic; Matthew Brown – Department of Physiology and Biomedical Engineering, Mayo Clinic; Patrick Vanderboom – Division of Endocrinology, Diabetes, and Metabolism, Mayo Clinic; Aoife Egan – Division of Endocrinology, Diabetes, and Metabolism, Mayo Clinic; Adrian Vella – Division of Endocrinology, Diabetes, and Metabolism, Mayo Clinic; Ian Lanza – Division of Endocrinology, Diabetes, and Metabolism, Mayo Clinic; Tushar Patel – Department of Transplantation, Mayo Clinic; Aleksey Matveyenko – Department of Physiology and Biomedical Engineering, Mayo Clinic
On Demand

OS23.3 - Synergy between 15-lipoxygenase and secreted PLA2 promotes inflammation by formation of TLR4 agonists from extracellular vesiclesMateja Manček Keber – National Institute of Chemistry; Van Thai Ha – National Institute of Chemistry; Duško Lainšček – National Institute of Chemistry; Bernd Gesslbauer – University of Graz; Eva Jarc – Jožef Stefan Institute; Tuulia Hyötyläinen – Örebro University; Nejc Ilc – University of Ljubljana; Katja Lakota – University Medical Centre Ljubljana; Matija Tomšič – University Medical Centre Ljubljana; Fons A.J. van de Loo – Radboud University Medical Center; Valery Bochkov – University of Graz; Toni Petan – Jožef Stefan Institute; Roman Jerala – National Institute of Chemistry
On Demand

OS23.4 - Monocytes traffic extracellular vesicles to damaged muscle and adopt a novel immunophenotype to support muscle regenerationRussell G. Rogers, III, PhD – Smidt Heart Institute, Cedars-Sinai Medical Center; Akbarshakh Akhmerov, M.D. – Smidt Heart Institute, Cedars-Sinai Medical Center; Weixin Liu – Smidt Heart Institute, Cedars-Sinai Medical Center; Lizbeth Sanchez – Smidt Heart Institute, Cedars-Sinai Medical Center; Eduardo Marbán – Smidt Heart Institute, Cedars-Sinai Medical Center
On Demand

OS23.5 - Microglial derived extracellular vesicles activate autophagy and mediate multi-target signaling to maintain cellular homeostasisBram Van den Broek – Hasselt university; Isabel Pintelon – Antwerp university; Ibrahim Hamad – Hasselt university; Mansour Haidar – Hasselt University; Niels Hellings – Hasselt University; Jerome Hendriks – Hasselt University; Markus Kleinewietfeld – Hasselt University; Jean-Pierre Timmermans – Antwerp University; Vincent Timmerman – Antwerp university; Veerle Somers – Hasselt University; Luc Michiels – Hasselt University; Joy I. Irobi, PhD – Hasselt University; Joy I. Irobi, PhD – Hasselt University
On Demand

OS23.6 - Evaluation of Plasma Extracellular Vesicles as Biomarkers for LongevityXin Zhang, N/A – Laboratory Medicine Center, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, P. R. China; Virginia Kraus, MD, MD PhD – Division of Rheumatology, Duke Molecular Physiology Institute, Duke University School of Medicine
On Demand

OS24.1 - Scaling-up the manufacturing of well-characterized mesenchymal stromal cell-derived extracellular vesicles for biomedical applicationsAna Fernandes-Platzgummer – Department of Bioengineering and iBB – Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal; Sara Rosa – Department of Bioengineering and iBB – Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal; Ricardo Silva – Department of Bioengineering and iBB – Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal; Raquel MS Cunha, PhD – Instituto Superior Técnico, University of Lisbon; Miguel Almeida Fuzeta, MSc – Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal; Cecília Calado – Instituto Superior de Engenharia de Lisboa; Carla Carvalho – Department of Bioengineering and iBB – Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal; Joaquim Cabral – Department of Bioengineering and iBB – Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal; Ana Azevedo – Department of Bioengineering and iBB – Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal; Cláudia Silva – Department of Bioengineering and iBB – Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal
On Demand

OS25.2 - Fibroblast Growth Factor 2-mediated Regulation of Neuronal Exosome Release Depends on VAMP3/cellubrevin in Hippocampal Neurons.Thomas Koeglsperger, Dr. – German Center for Neurodegenerative Diseases (DZNE); Thomas Koeglsperger, Dr. – German Center for Neurodegenerative Diseases (DZNE); Rohit Kumar – German Center for Neurodegenerative Diseases (DZNE); Qilin Tang – German Center for Neurodegenerative Diseases (DZNE); Stephan A. Müller – German Center for Neurodegenerative Diseases (DZNE); Pan Gao – German Center for Neurodegenerative Diseases (DZNE); Mahlstedt Diana – German Center for Neurodegenerative Diseases (DZNE); Yi Tan – German Center for Neurodegenerative Diseases (DZNE); Klingl Andreas – Department of Biology, Ludwig Maximilian University, Munich; Kai Bötzel – Department of Neurology, Ludwig Maximilian University, Munich; Stefan F. Lichtenthaler – German Center for Neurodegenerative Diseases (DZNE); Günter Höglinger – German Center for Neurodegenerative Diseases (DZNE)
On Demand

OS25.3 - The well-chaperoned extracellular vesicle: their presence in neuropathologiesXiaoli Yu – University of Colorado Denver, Anschutz Medical Campus, Department of Neurosurgery; Anthony Fringuello – University of Colorado Denver, Anschutz Medical Campus, Department of Neurosurgery; Steven G. Griffiths – X0S0ME; Brooke Metzger – Illinois College; Michael W. Graner – University of Colorado Anschutz Medical Campus
On Demand

OS25.4 - Methamphetamine Use Disorder Uniquely Plasma Extracellular Vesicle MiRNA ExpressionUrsula S. Sandau, PhD – Oregon Health and Science University; Erika Duggan – Scintillon Institute; Xiao Shi – VA Portland Health Care System; Oregon Health and Science University; Tracy Swanson – VA Portland Health Care System; Oregon Health and Science University; Marilyn Huckans – VA Portland Health Care System; Methamphetamine Abuse Research Center; Sierra Smith – Oregon Health and Science University; Jennifer Loftis – VA Portland Health Care System; Methamphetamine Abuse Reaseach System; aaron Janowsky – VA Portland Health Care System; Methamphetamine Abuse Reaseach System; Oregon Health and Science University; John Nolan – Scintillon Institute; Julie A. Saugstad – Oregon Health and Science University
On Demand

OS25.6 - Bone marrow-derived extracellular vesicles may alter the aging phenotype of murine hematopoietic stem cells.sicheng Wen, MD, PhD – Rhode Island Hospital/ Brown University; Jill Kreiling – Brown University; Mark Dooner – Rhode Island Hospital; Elaine papa – Rhode Island Hospital; Michael Del Tatto – Rhode Island Hospital; yan Cheng – Rhode Island Hospital; Mandy Pereira – Rhode Island Hospital; Peter Quesenberry – Rhode Island Hospital; Laura R. Goldberg, MDPhD – Brigham and Women's Hospital
On Demand

OS27.2 - Detecting Tumor-Associated Membrane Receptors on Extracellular Vesicles via immuno-PCR with Affibody-DNA-ConjugatesChristiane Stiller, PhD – Uppsala University; Petra Hååg – Karolinska Institute; Elizabeth Paz Gomero – KTH Royal Institute of Technology; Vasiliki Arapi – Karolinska Institute; Kristina Viktorsson – Karolinska Institute; Rolf Lewensohn – Karolinska Institute; Amelie E. Karlström – KTH Royal Institute of Technology
On Demand

OS27.4 - Integrated omics reveal conserved and divergent modulation of cardiovascular disease by tissue-entrapped extracellular vesiclesMark C. Blaser, PhD – Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Fabrizio Buffolo, MD – Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Arda Halu, PhD – Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Florian Schlotter, MD – Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Hideyuki Higashi, MSc – Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Lorena Pantano Rubino, PhD – The Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Boston, MA, 02139, U.S.A.; Louis A. Saddic, MD, PhD – Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Samantha Atkins – Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Maximillian A. Rogers, PhD – Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Tan H. Pham, BSc – Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Eugenia Shvartz, MS – Center for Excellence in Vascular Biology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Galina K. Sukhova, PhD, MS – Center for Excellence in Vascular Biology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Silvia Monticone, MD, PhD – Division of Internal Medicine and Hypertension, Department of Medical Sciences, University of Torino, Torino, Italy; Giovanni Camussi – Department of Medical Sciences, University of Torino; Simon C. Body, MD, MPH – Boston University School of Medicine, Boston, MA, 02118, U.S.A.; Jochen D. Muehlschlegel, MD, MMSc – Center for Perioperative Genomics, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Peter Libby, MD – Center for Excellence in Vascular Biology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.A; Sasha A. Singh, PhD – Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Masanori Aikawa, MD, PhD – Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Elena Aikawa, MDPhD – Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.
On Demand

OS27.6 - MiR-20a regulates exogenous CD82 expression on proliferation, invasion, migration and angiogenesis of gastric cancerTingting guo – Zhengzhou University
On Demand

OS27.8 - The value of exosomes as a potential biomarker for Devil Facial Tumour Disease.Camila Espejo – University of Tasmania; Richard Wilson – University of Tasmania; Greg Woods – University of Tasmania; Bruce Lyons – University of Tasmania
On Demand

OS28.4 - One Size Does Not Fit All: Overcoming Barriers to Successful Discovery and Scaled Manufacturing of Therapeutic Extracellular VesiclesJieun Lee, PhD – AgeX Therapeutics Inc.; Wei Guo – University of Pennsylvania; Hal Sternberg – AgeX Therapeutics Inc; Mike West – AgeX Therapeutics Inc.; Dana Larocca, PhD – AgeX Therapeutics Inc.; Dana Larocca, PhD – AgeX Therapeutics Inc.
On Demand

OS28.5 - Structural Insight to Interactions of Extracellular Vesicles and Membrane Active Anticancer-Antimicrobial PeptidesTamas Beke-Somfai, PhD – PI; Tamas Beke-Somfai, PhD – PI; Imola Szigyarto; Priyanka Singh – Ms; Mayra Quemé-Pena – Research Centre for Natural Sciences; Szilvia Bősze – Eötvös Loránd University; Tünde Juhász – Research Centre for Natural Sciences; Ference Zsila – Research Centre for Natural Sciences; Zoltan Varga, PhD – Biological Nanochemistry Research Group, Institute of Materials and Environmental Chemistry, Research Center for Natural Sciences, Budapest, Hungary; Mihaly Judith – Research Centre for Natural Sciences
On Demand

OS29.1 - A specific non-coding RNA in extracellular vesicles from induced neuronal cells and epigenetic regulation of neurotransmissionEllen Tedford – Cambridge University; Norhidayah Badya – U of Leeds; Conor Laing – University of Leeds; Glenn McConkey, PhD – University of Leeds; Glenn McConkey, PhD – University of Leeds
On Demand

OS29.4 - Human CD4+ T regulatory-derived extracellular vesicles and associated microRNAs: role in cell-to-cell communication and involvement in the loss of immune tolerance during multiple sclerosisSilvia Garavelli – Laboratorio di Immunologia, Istituto di Endocrinologia e Oncologia Sperimentale, Consiglio Nazionale delle Ricerche (IEOS-CNR), Naples, Italy; Claudio Procaccini – Laboratorio di Immunologia, Istituto di Endocrinologia e Oncologia Sperimentale, Consiglio Nazionale delle Ricerche (IEOS-CNR), Naples, Italy; Alessandra Colamatteo – Treg Cell Laboratory, Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università Degli Studi di Napoli "Federico II", Naples, Italy; Fortunata Carbone – Laboratorio di Immunologia, Istituto di Endocrinologia e Oncologia Sperimentale, Consiglio Nazionale delle Ricerche (IEOS-CNR), Naples, Italy; Elena Tagliabue – IRCCS MultiMedica; Donatella Carpi – Joint Research Centre, Ispra, Varese, Italy; Laura Cantone – EPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano; Valentina Bollati – EPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano; Ilaria Giusti – Department of Life Health and Environmental Sciences, University of L'Aquila, Italy; Vincenza Dolo – Department of Life, Health and Environmental Sciences, University of L'Aquila; Sarah Grossi – Universita' degli Studi dell’Insubria, Dipartimento di biotecnologie e scienze della vita, Varese, Italy; Paola Campomenosi – Universita' degli Studi dell’Insubria, Dipartimento di biotecnologie e scienze della vita, Varese, Italy; Dario Di Silvestre – Istituto di Tecnologie Biomediche, Consiglio Nazionale delle Ricerche (ITB-CNR), 20090 Segrate, Milano, Italy; Pierluigi Mauri – Istituto di Tecnologie Biomediche, Consiglio Nazionale delle Ricerche (ITB-CNR), 20090 Segrate, Milano, Italy; Annibale Puca – IRCCS MultiMedica; Fabio Buttari – Unit of Neurology and Unit of Neurorehabilitation, IRCCS Istituto Neurologico Mediterraneo (INM) Neuromed, Pozzilli, IS, Italy; Diego Centonze – Unit of Neurology and Unit of Neurorehabilitation, IRCCS Istituto Neurologico Mediterraneo (INM) Neuromed, Pozzilli, IS, Italy; Veronica De Rosa – Laboratorio di Immunologia, Istituto di Endocrinologia e Oncologia Sperimentale, Consiglio Nazionale delle Ricerche (IEOS-CNR), Naples, Italy; Giuseppe Matarese – Treg Cell Laboratory, Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università Degli Studi di Napoli "Federico II", Naples, Italy; Paola de Candia – IRCCS MultiMedica; Paola de Candia – IRCCS MultiMedica
On Demand

OS29.5 - Revealing the proteome of Brain Derived Extracellular Vesicles isolated from human Amyotrophic Lateral Sclerosis post-mortem tissues.Natasha Vassileff – The Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria, Australia.; Laura J Vella – The Florey Institute of Neuroscience and Mental Health, University of Melbourne; Harinda Rajapaksha – La Trobe Institute for Molecular Science; Mitch Shambrook – Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, Australia; Amirmohammad Nasiri Kenari, PhD student – Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, VIC, Australia; Jacky Chan – The Florey Institute of Neuroscience and Mental Health; Catriona McLean – The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, Australia.; Andrew F Hill – Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University; Lesley Cheng – Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University
On Demand

OS29.6 - Separation of microglial EVs from human brain-derived EVsTanina Arab, PhD – Department of Molecular and Comparative Pathobiology, Johns Hopkins School of Medicine, Johns Hopkins University, Baltimore, MD, USA; Yiyao Huang – Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine; Vasiliki Machairaki – Department of Neurology, Johns Hopkins University School of Medicine; Juan Troncoso – Department of Neurology, Johns Hopkins University School of Medicine; Olga Pletniková – Department of Pathology, Johns Hopkins University School of Medicine; Kenneth Witwer – Department of Molecular and Comparative Pathobiology and Department of Neurology, The Johns Hopkins University School of Medicine
Monday, Jul 20
12:54 PM – 1:03 PM

Towards reference intervals of extracellular vesicles in human plasma by flow cytometryBo Li – Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University; Edwin van der Pol – Department of Clinical Chemistry, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Vesicle Observation Center, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Department of Biomedical Engineering and Physics, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Lei Zheng – Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China; Rienk nieuwland – Department of Clinical Chemistry, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands, Vesicle Observation Center, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
Monday, Jul 20
2:16 PM – 2:26 PM

Urinary Extracellular Vesicles-perspectives and challenges for biomedical research and clinical utilizationAlicia Llorente – Dept. of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.; Elena S. Martens-Uzunova – Erasmus Medical Center; Kenneth Witwer – Department of Molecular and Comparative Pathobiology and Department of Neurology, The Johns Hopkins University School of Medicine
Monday, Jul 20
3:57 PM – 4:07 PM

Blood based assays for glioma diagnosis and monitoringLeonora Balaj, MDPhD – Massachusetts General Hospital and Harvard Medical School
Monday, Jul 20
4:07 PM – 4:20 PM

Regulatory points in EV-based liquid biopsy – translational implicationsJanusz Rak, MD, PhD – McGill University
Wednesday, Jul 22
3:31 PM – 3:42 PM

Increased Hematopoietic Extracellular RNAs andVesicles in the Lung during Allergic AirwayResponses Heather H. Pua, MD, PhD – Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center
Disease
On Demand

OT01.8 - Use of an alternating current electrokinetic microelectrode chip to positively identify oncology, neurology, and infectious disease samples through plasma extracellular vesicle analysisRajaram Krishnan, PhD – Biological Dynamics, Inc.; Jean Lewis, MD PhD – Biological Dynamics, Inc.; David Searson – Biological Dynamics, Inc.; Orlando Perrera – Biological Dynamics, Inc.; Alfred Kinana, MD PhD – Biological Dynamics, Inc.; Heath Balcer, MD PhD – Biological Dynamics, Inc.; Rajaram Krishnan, PhD – Biological Dynamics, Inc.
On Demand

OT04.1 - Endo-lysosomes as an alternative intracellular location for EV cargo delivery with disease relevanceGiona Pedrioli, MSc – Laboratory for Biomedical Neurosciences, LBN-EOC; Marialuisa Barberis – Laboratory for Biomedical Neurosciences, LBN-EOC; Diego Morone – Istituto di Ricerca in Biomedicina; Paolo Paganetti – Laboratory for Biomedical Neurosciences, LBN-EOC
On Demand

OT06.1 - Regulation of liver homeostasis, regeneration and diseases by mesenchymal stem cell-derived apoptotic extracellular vesiclesBingdong Sui – University of Pennsylvania
On Demand

OT06.2 - MSC-sEVs restore structural and mechanical properties in a rabbit model of cartilage injuryWei seong Toh, PhD – Faculty of Dentistry, National University of Singapore, Singapore. Department of Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore. Tissue Engineering Program, Life Sciences Institute, National University of Singapore, Singapore. Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore; Wei seong Toh, PhD – Faculty of Dentistry, National University of Singapore, Singapore. Department of Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore. Tissue Engineering Program, Life Sciences Institute, National University of Singapore, Singapore. Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore; Shipin zhang, MD PhD – Faculty of Dentistry, National University of Singapore, Singapore. Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Francis Keng lin Wong, MCI, F.R.C.S., F.A.M.S. – Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Department of Orthopaedic Surgery, Sengkang General Hospital, Singhealth, Singapore; Barry Wei Loong Tan, MBBS – Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; James Hoi Po Hui, F.R.C.S., F.A.M.S., M.D. – Tissue Engineering Program, Life Sciences Institute, National University of Singapore, Singapore. Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Sai Kiang Lim, MDPhD – Institute of Medical Biology, Agency for Science, Technology and Research, Singapore. Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Sai Kiang Lim, MDPhD – Institute of Medical Biology, Agency for Science, Technology and Research, Singapore. Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
On Demand

OT10.2 - Protective effects of extracellular vesicles derived from induced pluripotent stem cells in acute kidney injury modelRafael S. Lindoso, PhD – Federal University of Rio de Janeiro; Rafael S. Lindoso, PhD – Federal University of Rio de Janeiro; Federica Collino, PhD – Pediatric Nephrology, Dialysis and Transplant Unit, Fondazione Ca' Granda IRCCS Ospedale Maggiore Policlinico of Milan; Jarlene Alécia Lopes – Federal University of Rio de Janeiro; Marta Tapparo – Department of Medical Sciences, Molecular Biotechnology Center, University of Torino; Giovane Tortelote – Department of Pediatrics' Section of Pediatric Nephrology, Tulane University School of Medicine; Taís Kasai-Brunswick – Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro; Gustavo Lopes – Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro; Douglas Barroso – Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro; Renata Skovronova – Department of Molecular Biotechnology and Health Sciences, University of Torino; Camila Wendt – Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro; Kildare Miranda – Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro; Benedetta Bussolati, MD, PhD – University of Torino; Adalberto Vieyra – Federal University of Rio de Janeiro
On Demand

OT10.4 - Epigenetic regulation of fetal hypoplastic lungs by amniotic fluid stem cell derived extracellular vesiclesLina Antounians, MSc – The Hospital for Sick Children; Huayun Hou – The Hospital for Sick Children; Cadia Chan – The Hospital for Sick Children; Michael Wilson – The Hospital for Sick Children; Augusto Zani – The Hospital for Sick Children; Augusto Zani – The Hospital for Sick Children
On Demand

OF14.1 - Extracellular vesicles - a tattletale for rare gene editing eventsKoen Breyne, PhD – MGH-Harvard Medical School; Stefano Ughetto – MGH-Harvard Medical School; Xandra O Breakefield – MGH-Harvard Medical school
On Demand

OF14.5 - Staphylococcus aureus secrete immunomodulatory RNA and DNA via extracellular vesiclesBlanca V. Rodriguez, MS – Duke University; Meta Kuehn – Duke University
On Demand

OF14.6 - Urinary extracellular vesicles transcriptome in diabetic kidney diseaseOm Dwivedi – Institute for Molecular Medicine Finland FIMM, University of Helsinki, Finland; Maija Puhka – Institute for Molecular Medicine Finland FIMM, University of Helsinki, Finland; Karina A. Barreiro, MSc – Institute for Molecular Medicine Finland FIMM, University of Helsinki, Finland; erkka valo – Folkhälsan Institute of Genetics, Folkhälsan Research Center, Helsinki, Finland; Harry Holthofer – Institute for Molecular Medicine Finland FIMM, University of Helsinki, Finland; per-henrik Groop – Abdominal Center Nephrology, University of Helsinki and Helsinki University Hospital, Finland; Carol Forsblom – Folkhälsan Institute of Genetics, Folkhälsan Research Center, Helsinki, Finland; tiinamaija tuomi – Hospital District of Helsinki and Uusimaa (HUS), Helsinki, Finland; Leif Groop – Institute for Molecular Medicine Finland FIMM, University of Helsinki, Finland
On Demand

OF17.1 - The Proteome of Circulating Large EVs in Diabetes and HypertensionDylan Burger, PhD – Chronic Disease Program, Ottawa Hospital Research Institute; Dylan Burger, PhD – Chronic Disease Program, Ottawa Hospital Research Institute; Ozgun Varol – Ottawa Hospital Research Institute; Maddison Turner – Ottawa Hospital Research Institute; Christopher Kennedy – Ottawa Hospital Research Institute
On Demand

OS22.4 - A novel method for the delivery of cell-free therapy to fetuses with congenital anomalies: a proof of principle studyLina Antounians, MSc – The Hospital for Sick Children; Lina Antounians, MSc – The Hospital for Sick Children; Louise Montalva – The Hospital for Sick Children; Gabriele Raffler – The Hospital for Sick Children; Maria Sole Gaffi – The Hospital for Sick Children; Augusto Zani – The Hospital for Sick Children; Augusto Zani – The Hospital for Sick Children
On Demand

OS27.6 - MiR-20a regulates exogenous CD82 expression on proliferation, invasion, migration and angiogenesis of gastric cancerTingting guo – Zhengzhou University
On Demand

OS27.8 - The value of exosomes as a potential biomarker for Devil Facial Tumour Disease.Camila Espejo – University of Tasmania; Richard Wilson – University of Tasmania; Greg Woods – University of Tasmania; Bruce Lyons – University of Tasmania
Wednesday, Jul 22
2:18 PM – 2:28 PM

EV in vitro modelsIrina Nazarenko – Institute for Infection Prevention and Hospital Epidemiology; Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany
Wednesday, Jul 22
2:41 PM – 2:52 PM

EVs in bacterial and non-mammalian diseasesMaria Kaparakis-Liaskos – Department of Physiology, Anatomy and Microbiology, La Trobe University, Victoria, Australia.
Wednesday, Jul 22
2:52 PM – 3:02 PM

EVs in regenerationSusmita Sahoo – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai
Disease: Cancer
On Demand

OT01.6 - A Capillary-Channeled Polymer (C-CP) Fiber Spin-Down Tip Approach for the Isolation and Biomarker Characterization of Extracellular Vesicles of Ovarian Cancer OriginKaylan K. Jackson – Clemson University; Rhonda R. Powell – Clemson University; Terri F. Bruce, MDPhD – Clemson University; R. Kenneth Marcus – Clemson University
On Demand

OT02.1 - Identification of critical modifying factors in EV-based communication between colorectal cancer and stromal cells using the organoid modelZsuzsanna Szvicsek – Semmelweis University, Department of Genetics, Cell and Immunobiology, Molecular Cancer Research Group, Budapest, Hungary; Adam Oszvald – Semmelweis University, Department of Genetics, Cell and Immunobiology; Anikó Zeöld – Semmelweis University, Department of Genetics, Cell and Immunobiology, Molecular Cancer Research Group, Budapest, Hungary; Andrea Kelemen – Semmelweis University, Department of Genetics, Cell and Immunobiology, Molecular Cancer Research Group, Budapest, Hungary; Tamás Tölgyes – Uzsoki Hospital, Budapest, Hungary; Kristóf Dede – Uzsoki Hospital, Budapest, Hungary; Attila Bursics – Uzsoki Hospital, Budapest, Hungary; Edit Buzás – Semmelweis University, Department of Genetics, Cell and Immunobiology, MTA-SE Immune-Proteogenomics Extracellular Vesicle Research Group, Budapest, Hungary and HCEMM_SE Extracellular Vesicle Research Group; Zoltán Wiener, PhD – Semmelweis University, Department of Genetics, Cell and Immunobiology, Molecular Cancer Research Group, Budapest, Hungary
On Demand

OT02.2 - Prostate Cancer-derived EVs Induce a Pro-inflammatory Phenotype in the StromaBlandine F. Victor, MS – Cedars-Sinai Medical Center; Dolores Di Vizio – Cedars-Sinai Medical Center; Andrew Chin – Cedars-Sinai; Tatyana Vagner, PhD – Cedars-Sinai Medical Center; Javier Mariscal – Cedars-Sinai Medical Center; Mandana Zandian – Cedars-Sinai Medical Center; Catherine Grasso – Cedars-Sinai Medical Center; Roberta Gottlieb – Cedars-Sinai Medical Center; Helen Goodridge – Cedars-Sinai Medical Center
On Demand

OT02.3 - The αvβ6 integrin in cancer cell-derived small extracellular vesicles enhances angiogenesisShiv Ram Krishn, PhD – Thomas Jefferson University, Philadelphia, USA; Israa Salem – Thomas Jefferson University; Fabio Quaglia, PhD – Thomas Jefferson University; Nicole M. Naranjo – Thomas Jefferson University; Ekta Agarwal – The Wistar Institute; Peter A. McCue – Thomas Jefferson University; Paul H. Weinreb – Biogen Inc.; Shelia M. Violette – Biogen; Dario C. Altieri – Immunology, Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, PA 19104 USA; Lucia R. R. Languino, PhD – Department of Cancer Biology, Thomas Jefferson University
On Demand

OT02.4 - Prostate cancer exosomes promote bone metastasis in a cholesterol-dependent mannerStephen E. Henrich – Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611; Kaylin McMahon – Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611; Michael Plebanek – Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611; Fabio Tavora – Brown University, Providence, RI, 02912; Andre De Souza – Lifespan Cancer Institute, Providence, RI, 02903; Anthony Mega – Lifespan Cancer Institute, Providence, RI, 02903; Benedito Carneiro – Brown University, Providence, RI, 02912; Colby Thaxton – Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611; Simpson Querrey Institute for BioNanotechnology, Northwestern University, Chicago, IL, 60611; Robert H. Lurie Comprehensive Cancer Center Northwestern University, Chicago IL, 60611
On Demand

OT02.5 - Low aggressive HNSCC-derived EVs regulates metastatic potential of highly metastasized HNSCC.Shinya Sato, MD, PhD – Division of Molecular Pathology and Genetics, Kanagawa Cancer Center Research Institute; Michael Korrer – Department of Otolaryngology, Vanderbilt University Medical Center; Sohini Roy – Department of Otolaryngology, Vanderbilt University Medical Center; Young Kim – Department of Otolaryngology, Vanderbilt University Medical Center; Alissa Weaver – Department of Cell and Developmental Biology, Vanderbilt University School of Medicine
On Demand

OT02.6 - Desmoglein 2 enhances squamous cell carcinoma tumor development through extracellular vesicles in an IL-8/miR-146a-dependent mechanismJoseph P. Flemming – Thomas Jefferson University; Mohammed Haque – Thomas Jefferson University; Brianna L. Hill – Thomas Jefferson University; James Wahl – UNMC; Kenneth Tsai – Moffitt Cancer Center; Peter Wermuth – TJU; Andrew Overmiller – Thomas Jefferson University; My Mahoney – Thomas Jefferson University
On Demand

OT04.3 - Anti-human Fab fragment of CD9 antibody prevents the endocytosis of melanoma and colon cancer-derived extracellular membrane vesicles and nuclear transfer of their cargosAurelio Lorico, MD, PhD – Touro University Nevada College of Medicine; Mark Santos – Touro University College of Medicine; Jana Karbanová – Technische Universität Dresden; Kevin Huang – Touro University Nevada College of Medicine; Tony Huynh – Touro University Nevada College of Medicine; Gyunghwi Woo – Touro University Nevada College of Medicine; Cheryl Vanier – Touro University Nevada; Chikao Morimoto – Juntendo University; Germana Rappa – Touro University Nevada College of Medicine; Denis Corbeil – Tissue Engineering Laboratories, Technische Universität Dresden,; Aurelio Lorico, MD, PhD – Touro University Nevada College of Medicine
On Demand

OT09.5 - Role of membrane protein palmitoylation in extracellular vesicle biogenesis in squamous cell carcinomaMohammed Haque – Thomas Jefferson University; Joseph P. Flemming – Thomas Jefferson University; Brianna L. Hill – Thomas Jefferson University; James Wahl – UNMC; My Mahoney – Thomas Jefferson University
On Demand

OT09.6 - Translation initiation factor eIF4E reprograms the vesiculation of cancer cellsEsterina D'Asti – University of Montreal; Biljana Culjkovic-Kraljacic – University of Montreal; Héloïse Chassé – University of Montreal; Jadwiga Gasiorek – University of Montreal; Gavin Morris – University of Montreal; Katherine Borden – University of Montreal
On Demand

OF12.4 - Dietary cross-species communication: context-dependent role of bovine extracellular vesicles in cancer progressionRahul Sanwlani, MSc – La Trobe Institute for Molecular Sciences, La Trobe University, Melbourne, Australia; Monisha Samuel – La Trobe Institute for Molecular Sciences, La Trobe University, Melbourne, Australia; Suresh Mathivanan – La Trobe University
On Demand

OF15.6 - RNA nanoparticles as EV displaying ligands for specific cancer targeting and efficient RNAi delivery in vivoZhefeng Li, PhD – College of Pharmacy, The Ohio State University; Fengmei Pi, PhD – ExonanoRNA; Zhen Zheng – Center for RNA Nanobiotechnology and Nanomedicine; College of Pharmacy; Comprehensive Cancer Center; Dorothy M. Davis Heart and Lung Research Institute; College of Medicine. The Ohio State University; Peixuan Guo – Center for RNA Nanobiotechnology and Nanomedicine; College of Pharmacy; Comprehensive Cancer Center; Dorothy M. Davis Heart and Lung Research Institute; College of Medicine. The Ohio State University
On Demand

OF16.1 - Multiplex Nanoscale Flow Cytometry to Study the Circulating Extracellular Vesicle Biome in Patients with Pancreatic Cancer versus Screen Negative ControlsMayu Morita – OHSU; Thuy Ngo – Knight CEDAR Technology, OHSU; Emek Demir – OHSU; Randall Armstrong – OHSU; Scott Bornheimer – BD Biosciences; Terry K. Morgan, MD, PHD – OHSU; Terry K. Morgan, MD, PHD – OHSU
On Demand

OF16.2 - Analysis of surface markers as biomarkers for small cell lung cancerPatricia Midori M. M. Murobushi Ozawa, PhD – Department of Cell and Developmental Biology, Vanderbilt University School of Medicine; Sarah M. Groves – Department of Biochemistry, Vanderbilt University Medical Center; Vito Quaranta – Department of Biochemistry, Vanderbilt University Medical Center; Alissa Weaver – Department of Cell and Developmental Biology, Vanderbilt University School of Medicine
On Demand

OF16.3 - Leukobiopsy – exploiting extracellular vesicle-mediated leukocyte sequestration of cancer-specific signaturesJanusz Rak, MD, PhD – McGill University; Janusz Rak, MD, PhD – McGill University; Shipa Chennakrishnaiah – McGill University; Laura Montermini – RIMUHC; Brian Meehan – RIMUHC; Thupten Tsering – RIMUHC; Saro Aprikian – McGill University; Dongsic Choi – RIMUHC
On Demand

OF16.4 - Whole-Transcriptomic Profiling of Circulating Small Extracellular Vesicles Derived RNAs for Early Detection of Colorectal Carcinoma and AdenomaLi Min, PhD – Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.; Shengtao Zhu – Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.; Xiang Liu – Echo Biotech Co., Ltd, Beijing, China.; Da Qin – Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.; Qingdong Guo – Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.; Rui Wei – Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.; Libo Zhao – Echo Biotech Co., Ltd, Beijing, China.; Guanyi Kong – Echo Biotech Co., Ltd, Beijing, China.; Shutian Zhang – Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.; Shutian Zhang – Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.
On Demand

OF16.5 - RNA Signatures from Blood and Urine EVs Display Tissue-Lineage from Prostate Cancer PatientsNavneet Dogra, PhD – Department of Genetics and Genomic Sciences, Department of Pathology, Icahn School of Medicine, Mount Sinai; Navneet Dogra, PhD – Department of Genetics and Genomic Sciences, Department of Pathology, Icahn School of Medicine, Mount Sinai; Mehmet Ahsen – Icahn School of Medicine at Mount Sinai; Tina Chen – Icahn School of Medicine at Mount Sinai; Reena Olsen – Icahn School of Medicine at Mount Sinai; Dan Han – Icahn School of Medicine at Mount Sinai; Stacey M. Gifford – IBM; Benjamin Wunsch – IBM; Rachel Weil – Icahn School of Medicine at Mount Sinai; Melissa Smith – Icahn School of Medicine at Mount Sinai; Joshua Smith – IBM; Sungchel Kim – IBM; Kamala Bhatt – Icahn School of Medicine at Mount Sinai; Sujit Nair – Icahn School of Medicine at Mount Sinai; Bojan Losic, MDPhD – Icahn School of Medicine at Mount Sinai; Robert Sebra – Icahn School of Medicine at Mount Sinai; Adam Margolin – Icahn School of Medicine at Mount Sinai; Carlos Cordon-Cardo – Icahn School of Medicine at Mount Sinai; Ashutosh Tewari – Icahn School of Medicine at Mount Sinai; GUSTAVO Stolovitzky – Icahn School of Medicine at Mount Sinai
On Demand

OF16.6 - A multi-model, liquid biopsy approach for diagnosing and staging pancreatic adenocarcinomaZijian Yang, MS – University of Pennsylvania; Michael LaRiviere – University of Pennsylvania; Jina Ko, PhD – Massachusetts General Hospital, Wyss Institute at Harvard University; Jacob Till – University of Pennsylvania; Theresa Christensen – University of Pennsylvania; Stephanie Yee – University of Pennsylvania; Taylor Black – University of Pennsylvania; Kyle Tien – University of Pennsylvania; Andrew A. Lin – University of Pennsylvania; Hanfei Shen – University of Pennsylvania; Andrew Adallah – University of Pennsylvania; Mark O'Hara – University of Pennsylvania; Charles Vollmer – University of Pennsylvania; Bryson Katona – University of Pennsylvania; Ben Stanger – University of Pennsylvania; David Issadore, MDPhD – Department of Bioengineering, University of Pennsylvania; Erica Carpenter – University of Pennsylvania
On Demand

OF18.4 - Comparative proteomics from different cancer cell types reveals novel mechanisms of Rab11-exosome subtype regulationPauline Marie – University of Oxford; Shih-Jung Fan, MD PhD – University of Oxford; John Mason – University of Oxford; Claudia Mendes – University of Oxford; Mark Wainwright, MD PhD – University of Oxford; Adrian Harris – University of Oxford; Clive Wilson – University of Oxford; Deborah C I Goberdhan, PhD – University of Oxford; Deborah C I Goberdhan, PhD – University of Oxford
On Demand

OS20.1 - Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signaling pathway in the recipient cellsPAMALI FONSEKA, PhD – La Trobe Institute for Molecular Sciences, La Trobe University; Hina Kalra – La Trobe University; Lahiru Gangoda – La Trobe University; Suresh Mathivanan – La Trobe University
On Demand

OS21.2 - Small extracellular vesicles modulated by the αVβ3 integrin reprogram recipient cells towards an aggressive neuroendocrine cancer phenotypeFabio Quaglia, PhD – Thomas Jefferson University; Shiv Ram Krishn, PhD – Thomas Jefferson University, Philadelphia, USA; George Daaboul, MDPhD – NanoView Biosciences; Srawasti Sarke – Thomas Jefferson University; Peter A. McCue – Thomas Jefferson University; William Kelly – Thomas Jefferson University; Qin Liu – Wistar Institute; Lucia R. R. Languino, PhD – Department of Cancer Biology, Thomas Jefferson University
On Demand

OS24.3 - Combinatorial antibody microarray profiling of intra- and extravesicular proteins in colorectal cancer cell line extracellular vesiclesRosalie martel, MEng – McGill University; Molly L. shen – McGill University; Philippe Decorwin-Martin, M.Eng – McGill University; Lucile Alexandre – McGill University; lorenna oliveira – McGill University; Andy Ng – McGill University; David Juncker, MDPhD – McGill University
On Demand

OS24.4 - Characterization of EVs using orthogonal techniques identifies discrete EV populations from a mouse dendritic cell lineBryce Killingsworth – Laboratory of Pathology, National Cancer Institute, National Institutes of Health; Timothy Traynor – Laboratory of Pathology, National Cancer Institute, National Institutes of Health; Joshua A. Welsh – Laboratory of Pathology, National Cancer Institute, National Institute of Health; Aleksandra Dakic – Laboratory of Pathology, National Cancer Institute, National Institutes of Health; Jason Savage – Laboratory of Pathology, National Cancer Institute, National Institutes of Health; Kevin Camphausen – Radiation Oncology Branch, National Cancer Institute, National Institutes of Health; Kenneth Aldape – Laboratory of Pathology, National Cancer Institute, National Institutes of Health; Jennifer Jones – Laboratory of Pathology, National Cancer Institute, National Institutes of Health
On Demand

OS24.5 - Hybrid plasmonic biomaterial nanofilter scaffold for cancer EV diagnostics based on surface-enhanced Raman scattering (SERS)Hanna J. Koster – Department of Biomedical Engineering, University of California, Davis; Tatu Rojalin, MD PhD – Department of Biomedical Engineering, University of California, Davis; Juanjuan Liu – Department of Bioengineering, McGill University; Sebastian Wachmann Hogiu, MD PhD – Department of Bioengineering, McGill University; Randy Carney, PhD – Department of Biomedical Engineering, University of California, Davis
On Demand

OS26.6 - Program to assess the rigor and reproducibility of extracellular vesicle-derived analytes for cancer detectionMatthew Young, PhD – National Cancer Institute; Sudhir Srivastava – National Cancer Institute
On Demand

OS27.2 - Detecting Tumor-Associated Membrane Receptors on Extracellular Vesicles via immuno-PCR with Affibody-DNA-ConjugatesChristiane Stiller, PhD – Uppsala University; Petra Hååg – Karolinska Institute; Elizabeth Paz Gomero – KTH Royal Institute of Technology; Vasiliki Arapi – Karolinska Institute; Kristina Viktorsson – Karolinska Institute; Rolf Lewensohn – Karolinska Institute; Amelie E. Karlström – KTH Royal Institute of Technology
On Demand

OS28.5 - Structural Insight to Interactions of Extracellular Vesicles and Membrane Active Anticancer-Antimicrobial PeptidesTamas Beke-Somfai, PhD – PI; Tamas Beke-Somfai, PhD – PI; Imola Szigyarto; Priyanka Singh – Ms; Mayra Quemé-Pena – Research Centre for Natural Sciences; Szilvia Bősze – Eötvös Loránd University; Tünde Juhász – Research Centre for Natural Sciences; Ference Zsila – Research Centre for Natural Sciences; Zoltan Varga, PhD – Biological Nanochemistry Research Group, Institute of Materials and Environmental Chemistry, Research Center for Natural Sciences, Budapest, Hungary; Mihaly Judith – Research Centre for Natural Sciences
Monday, Jul 20
12:35 PM – 12:36 PM

IntroductionAndrew Hill – The Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria, Australia.
Monday, Jul 20
12:36 PM – 12:49 PM

Featured Abstract: Ral GTPases promote metastasis by controlling biogenesis and organotropism of extracellular vesiclesshima ghoroghi – INSERM UMR_S1109, Tumor Biomechanics; Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France; Benjamin Mary – INSERM UMR_S1109, Tumor Biomechanics; Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France; Annabel LARNICOL – INSERM UMR_S1109, Tumor Biomechanics; Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France; François Delalande – LSMBO, Institut Pluridisciplinaire Hubert Curien, Strasbourg, France.; Christine Carapito – LSMBO, Institut Pluridisciplinaire Hubert Curien, Strasbourg, France; Nicodème Paul – INSERM UMR_S1109, Tumor Biomechanics; Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France; Raphael Carapito – INSERM UMR_S1109, Tumor Biomechanics; Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France; Olivier Lefebvre – INSERM UMR_S1109, Tumor Biomechanics; Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France; Jacky Goetz – INSERM UMR_S1109, Tumor Biomechanics; Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France; Vincent Hyenne – Tumor Biomechanics INSERM UMR_S 1109 Institut d’hématologie et d'immunologie,CNRS SNC5055, Strasbourg, France
Monday, Jul 20
3:57 PM – 4:07 PM

Blood based assays for glioma diagnosis and monitoringLeonora Balaj, MDPhD – Massachusetts General Hospital and Harvard Medical School
Tuesday, Jul 21
3:38 PM – 3:39 PM

IntroductionSusmita Sahoo – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai
Tuesday, Jul 21
3:39 PM – 3:49 PM

Nuclear proteins are recruited into tumor-derived extracellular vesicles upon expression of tetraspanin Tspan8Elena Grueso Navarro – Institute for Infection Prevention and Hospital Epidemiology; Medical Center-University of Freiburg, University of Freiburg, Freiburg, Germany; Andrea Gross – Institute for Infection Prevention and Hospital Epidemiology; Medical Center-University of Freiburg, University of Freiburg, Freiburg, Germany.; Amal Mohamed – Institute for Infection Prevention and Hospital Epidemiology; Medical Center-University of Freiburg, University of Freiburg, Freiburg, Germany.; Patrick Then – Leibniz Institute of Photonic Technology, Jena, Germany; Frank Garwe – Leibniz Institute of Photonic Technology, Jena, Germany; Domitille Schvartz – Department of Human Protein Sciences, Centre Médical Universitaire, Geneva, Switzerland; Jean-Charles Sanchez – Department of Human Protein Sciences, Centre Médical Universitaire, Geneva, Switzerland; Andreas Keller – Clinical Bioinformatics, University Hospital Saarland University, Saarbrücken, Germany; Joaquin Jurado Maqueda – Bioinf2Bio, Porto, Portugal. i3S-Instituto de Investigação e Inovação em Saúde Universidade do Porto, Porto, Portugal. Ipatimup-Institute of Molecular Pathology and Immunology University of Porto, Porto, Portugal.; Carla Oliveira – Bioinf2Bio, Porto, Portugal. i3S-Instituto de Investigação e Inovação em Saúde Universidade do Porto, Porto, Portugal. Ipatimup-Institute of Molecular Pathology and Immunology University of Porto, Porto, Portugal.; Irina Nazarenko – Institute for Infection Prevention and Hospital Epidemiology; Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany
Disease: Cardiovascular
On Demand

OT03.2 - Towards identification of protein components mediating cardiac repair by cardiac progenitor cell-derived extracellular vesiclesMarieke T. Roefs, M.T. – Department of Experimental Cardiology, University Medical Center Utrecht, Utrecht University, The Netherlands; Pieter Vader – Laboratory of Clinical Chemistry and Hematology, UMC Utrecht; Department of Experimental Cardiology, UMC Utrecht, The Netherlands; Joost Sluijter, J.P.G. – Department of Experimental Cardiology, University Medical Center Utrecht, Utrecht University, The Netherlands; Joost Sluijter, J.P.G. – Department of Experimental Cardiology, University Medical Center Utrecht, Utrecht University, The Netherlands
On Demand

OT03.3 - Hypoxia enhances the therapeutic potential of human CD34+ stem cell exosomes in ischemic hindlimb repairShweta Lodha, BA – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Morad Asadi – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Susmita Sahoo – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Marta Adamiak, PhD – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Cherrie Sherman – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Douglas Losardo – Feinberg Cardiovascular Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, IL; Rajesh Gupta – University of Toledo; Luca Musante – University of Virginia School of Medicine; Uta Erdbrügger – University of Virginia; Michael Davis – Emory University; David Kim – Feinberg Cardiovascular Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, IL
On Demand

OT03.4 - MiRNA-192 and -432 depleted c-kit+ progenitor cell exosomes promotes the proliferation, migration of mesenchymal stem cells and regulates inflammationHyun-Ji Park, PhD – Emory University; Jessica R. Hoffman – Emory University; Michael Davis – Emory University
On Demand

OF15.3 - Computational Modeling of Mesenchymal Stem Cell Exosomes Predicts Cardiac Improvements in Preclinical and Clinical Models of Hypoplastic Left Heart SyndromeJessica R. Hoffman – Emory University; Laxminarayana Korutla – University of Pennsylvania; Mohamed Abdullah – University of Maryland School of Medicine; Gregory Bittle – University of Maryland School of Medicine; Joshua Hare – University of Miami; Joey Harmon – University of Pennsylvania; Robert Hu – University of Pennsylvania; Rachana Mishra – University of Maryland School of Medicine; David Morales – University of Maryland School of Medicine; Sudhish Sharma – University of Maryland School of Medicine; Sunjay Kaushal – University of Maryland School of Medicine; Prashanth Vallabhajosyula – Yale University; Michael Davis – Emory University
On Demand

OF17.2 - Coronary artery disease ameliorates extracellular vesicle lncRNA PUNISHER regulates antigenic response and endothelial cells function via NFkB-dependent mechanismMohammed Rabiul Hosen, PhD – University of Bonn; Andreas Zietzer – University Hospital Bonn; Philip Goody, n/a – University Hospital Bonn; Monika Baumschabl – Molecular Cardiology, University Hospital Bonn; Anna Flender, n/a – University Hospital Bonn; Paula Levermann, n/a – University Hospital Bonn; Marc Sylvester, n/a – Institute of Biochemistry and Molecular Biology, University of Bonn; Nikos Werner – Krankenhaus der Barmherzigen Brüder Trier; Georg Nickenig – Heart Center Bonn, University Hospital Bonn; Felix Jansen – Heart Center Bonn, University Hospital Bonn
On Demand

OF17.4 - Adipose mesenchymal stromal cell derived EVs foster cardio-renal protection in the DOCA-salt hypertensive rat modelRafael S. Lindoso, PhD – Federal University of Rio de Janeiro; Jarlene Alécia Lopes – Federal University of Rio de Janeiro; Renata Binato – National Institute of Cancer; Eliana Abdelhay – National Institute of Cancer; christina Moeda Takiya – Federal University of Rio de Janeiro; Giovanni Montini; Benedetta Bussolati, MD, PhD – University of Torino; Adalberto Vieyra – Federal University of Rio de Janeiro; Federica Collino, PhD – Pediatric Nephrology, Dialysis and Transplant Unit, Fondazione Ca' Granda IRCCS Ospedale Maggiore Policlinico of Milan; Federica Collino, PhD – Pediatric Nephrology, Dialysis and Transplant Unit, Fondazione Ca' Granda IRCCS Ospedale Maggiore Policlinico of Milan
On Demand

OS27.4 - Integrated omics reveal conserved and divergent modulation of cardiovascular disease by tissue-entrapped extracellular vesiclesMark C. Blaser, PhD – Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Fabrizio Buffolo, MD – Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Arda Halu, PhD – Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Florian Schlotter, MD – Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Hideyuki Higashi, MSc – Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Lorena Pantano Rubino, PhD – The Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Boston, MA, 02139, U.S.A.; Louis A. Saddic, MD, PhD – Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Samantha Atkins – Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Maximillian A. Rogers, PhD – Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Tan H. Pham, BSc – Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Eugenia Shvartz, MS – Center for Excellence in Vascular Biology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Galina K. Sukhova, PhD, MS – Center for Excellence in Vascular Biology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Silvia Monticone, MD, PhD – Division of Internal Medicine and Hypertension, Department of Medical Sciences, University of Torino, Torino, Italy; Giovanni Camussi – Department of Medical Sciences, University of Torino; Simon C. Body, MD, MPH – Boston University School of Medicine, Boston, MA, 02118, U.S.A.; Jochen D. Muehlschlegel, MD, MMSc – Center for Perioperative Genomics, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Peter Libby, MD – Center for Excellence in Vascular Biology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.A; Sasha A. Singh, PhD – Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Masanori Aikawa, MD, PhD – Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.; Elena Aikawa, MDPhD – Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, 02115, U.S.A.
Tuesday, Jul 21
3:03 PM – 3:28 PM

Deconstructing Regenerative Medicine: From Cells to Exosomes and Defined FactorsEduardo Marbán – Smidt Heart Institute, Cedars-Sinai Medical Center
Disease: Immunological
On Demand

OT05.3 - Droplet-based Single Extracellular Vesicle Sequencing for Rare Immune Subtype DiscoveryJina Ko, PhD – Massachusetts General Hospital, Wyss Institute at Harvard University; Yongcheng Wang – Harvard University; David Weitz – Harvard University; Ralph Weissleder – Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School
On Demand

OT06.3 - Mesenchymal Stromal Cell Exosomes Educate Myeloid Cell Populations to Alleviate Neonatal Hyperoxia-Induced Lung InjuryGareth R. Willis, PhD – Harvard University & Boston Children's Hospital; Monica Reis – Harvard University & Boston Children's Hospital; Angeles Fernandez-Gonzalez – Harvard University & Boston Children's Hospital; Vincent Yeung – Harvard University & Boston Children's Hospital; Xianlan Liu – Boston Children's Hospital; S Alex Mitsialis – Harvard University & Boston Children's Hospital; Stella Kourembanas – Harvard University & Boston Children's Hospital
On Demand

OT06.4 - Immunomodulatory small extracellular vesicles derived from mesenchymal stem cells: A potential cell-free therapy for acute and chronic pulmonary vascular diseasesAlvin Tieu, BMSc, MSc – Clinical Epidemiology Program and Regenerative Medicine Program, Ottawa Hospital Research Institute; Casey Lansdell, MSc – Regenerative Medicine Program, Ottawa Hospital Research Institute; Duncan Stewart, MD – Ottawa Hospital Research Institute; Dylan Burger, PhD – Chronic Disease Program, Ottawa Hospital Research Institute; Manoj Lalu, MD, MDPhD – Clinical Epidemiology Program, Ottawa Hospital Research Institute
On Demand

OT06.6 - Changes in extracellular vesicle protein cargo after pro-inflammatory priming of umbilical cord mesenchymal stem cellsMairead Hyland, MSc Stem Cells and Regenerative Medicine – Keele University; Emma Wilson – University of Chester; Aled Clayton – Cardiff University; Claire Mennan – Keele University and RJAH Oswestry; Oksana Kehoe – Keele University
On Demand

OT10.6 - lncRNA EPHA6-1 in IFNβ-induced small extracellular vesicles promotes cytotoxicity of NK cells by acting as a ceRNA for hsa-miR-4485 to up-regulate NKp46 expressionShuang Li – Institute of Blood Transfusion, Peking Union Medical College; Anjing Zhu – Institute of Blood Transfusion, Chinese Academy of Medical Sciences Peking Union Medical College; Shilin Li – Institute of Blood Transfusion, Chinese Academy of Medical Sciences Peking Union Medical College; Limin Chen – Institute of Blood Transfusion, Chinese Academy of Medical Sciences Peking Union Medical College
On Demand

OF14.2 - Y-RNA subtype ratios in plasma extracellular vesicles are cell type specific and are candidate biomarkers for inflammatory diseasesTom Driedonks, PhD – Dept. Molecular & Comparative Pathobiology, Johns Hopkins School of Medicine; Sanne Mol – Dept. Biochemistry & Cell Biology, Fac. Veterinary Medicine, Utrecht University, The Netherlands; Sanne de Bruin – Dept. Intensive Care, Amsterdam University Medical Centers, location AMC, Amsterdam, The Netherlands; Anna-Linda Peters – Dept. Anesthesiology, University Medical Center Utrecht, Utrecht, The Netherlands; Xiaogang Zhang – Dept. Biochemistry & Cell Biology, Fac. Veterinary Medicine, Utrecht University, The Netherlands; Marthe Lindenbergh – Dept. Biochemistry & Cell Biology, Fac. Veterinary Medicine, Utrecht University, The Netherlands; Boukje Beuger – Dept. of Blood Cell Research, Sanquin Research, and Landsteiner Laboratory, Amsterdam University Medical Centers, Location AMC, Amsterdam, The Netherlands; Anne-Marieke Stalborch – Molecular Cell Biology lab, Dept. of Molecular and Cellular Hemostasis, Sanquin Research, and Landsteiner Laboratory, Amsterdam University Medical Centers, Location AMC, Amsterdam, The Netherlands; Thom Spaan – Dept. of Infectious Diseases & Immunity, Division of Virology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands; Esther de Jong – Dept. Experimental Immunology, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, The Netherlands; Erhard van der Vries – Dept. of Infectious Diseases & Immunity, Division of Virology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands; Coert Margadant – Molecular Cell Biology lab, Dept. of Molecular and Cellular Hemostasis, Sanquin Research, and Landsteiner Laboratory, Amsterdam University Medical Centers, Location AMC, Amsterdam, The Netherlands; Robin van Bruggen – Dept. of Blood Cell Research, Sanquin Research, and Landsteiner Laboratory, Amsterdam University Medical Centers, Location AMC, Amsterdam, The Netherlands; Alexander Vlaar – Dept. Intensive Care, Amsterdam University Medical Centers, location AMC, Amsterdam, The Netherlands; Tom Groot Kormelink – Dept. Experimental Immunology, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, The Netherlands; Esther Nolte-'t Hoen – Dept. Biomolecular Health Sciences, Fac. Veterinary Medicine, Utrecht University
On Demand

OF17.3 - Understanding the role of endothelial cell-derived apoptotic bodies in inflammatory signaling and cell clearance in an atherosclerosis model of inflammation.Amy A. Baxter, PhD – La Trobe University; Georgia Atkin-Smith – La Trobe University, Walter & Eliza Hall Institute for Medical Research; Stephanie Paone – St Pancras Clinical Research; Mark Hulett – La Trobe University; Ivan Poon – La Trobe University
On Demand

OF18.1 - Glycolytic restraint in alveolar macrophages is critical for vesicular secretion of suppressor of cytokine signaling 3Mikel D. Haggadone – University of Michigan Medical School; Jennifer Speth – University of Michigan Medical School; Hanna Hong – University of Michigan Medical School; Eric Zhang – University of Michigan; Costas Lyssiotis – University of Michigan Medical School; Marc Peters-Golden – University of Michigan Medical School
On Demand

OS19.4 - Amniotic fluid stem cell derived extracellular vesicles modulate pathogenic immune responses in experimental autoimmune encephalomyelitisGiorgia Manni, PhD – Department of Experimental Medicine, Section of Pharmacology, University of Perugia; Rita Romani – Department of Experimental Medicine, Sec. Biology; Marco Gargaro – Department of Experimental Medicine, Sec Pharmacology; Luisa Pascucci – Department of Veterinary Medicine; Pierluigi Orvietani – Department of Experimental Medicine, Sec. Phisiolgy and Biochemistry; Paolo Puccetti – Department of Experimental Medicine, Sec. Pharmacology; Vincenzo Nicola Talesa – Department of Experimental Medicine, Sec. of Biology; Francesca Fallarino – Department of Experimental Medicine, Sec. of Pharmacology
On Demand

OS21.1 - Continuous in vivo release of mast cell derived extracellular vesicles from an implanted device spreads pro-inflammatory response in miceKrisztina V. Vukman, PhD – Dept. of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary; Gábor Seregélyes – 1Dept. of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary; Tamás Visnovitz – Dept. of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary; Péter Lőrincz – Department of Anatomy, Cell and Developmental Biology, Eötvös Loránd University, Budapest, Hungary; Anna Koncz – Dept. of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary; Andrea Ferencz – Department of Surgical Research and Techniques, Semmelweis University, Budapest, Hungary; Daniella Fehér – Department of Surgical Research and Techniques, Semmelweis University, Budapest, Hungary; Krisztina Juhos – Department of Surgical Research and Techniques, Semmelweis University, Budapest, Hungary; Barabara Sódar – Dept. of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary; Krisztina Pálóczi – Dept. of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary; Eszter Tóth – Dept. of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary; András Försönits – Dept. of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary; Delaram Khamari – Dept. of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary; Alicia Galinsoga – Dept. of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary; Edit Buzás – Semmelweis University, Department of Genetics, Cell and Immunobiology, MTA-SE Immune-Proteogenomics Extracellular Vesicle Research Group, Budapest, Hungary and HCEMM_SE Extracellular Vesicle Research Group
On Demand

OS23.2 - Pro-inflammatory cytokine-mediated alterations in beta cell extracellular vesicle cargo and function enhance activation of the CXCL10-CXCR3 axis in diabetesNaureen Javeed, MSc, PhD – Department of Physiology and Biomedical Engineering, Mayo Clinic; Tracy Her – Department of Physiology and Biomedical Engineering, Mayo Clinic; Matthew Brown – Department of Physiology and Biomedical Engineering, Mayo Clinic; Patrick Vanderboom – Division of Endocrinology, Diabetes, and Metabolism, Mayo Clinic; Aoife Egan – Division of Endocrinology, Diabetes, and Metabolism, Mayo Clinic; Adrian Vella – Division of Endocrinology, Diabetes, and Metabolism, Mayo Clinic; Ian Lanza – Division of Endocrinology, Diabetes, and Metabolism, Mayo Clinic; Tushar Patel – Department of Transplantation, Mayo Clinic; Aleksey Matveyenko – Department of Physiology and Biomedical Engineering, Mayo Clinic
On Demand

OS23.3 - Synergy between 15-lipoxygenase and secreted PLA2 promotes inflammation by formation of TLR4 agonists from extracellular vesiclesMateja Manček Keber – National Institute of Chemistry; Van Thai Ha – National Institute of Chemistry; Duško Lainšček – National Institute of Chemistry; Bernd Gesslbauer – University of Graz; Eva Jarc – Jožef Stefan Institute; Tuulia Hyötyläinen – Örebro University; Nejc Ilc – University of Ljubljana; Katja Lakota – University Medical Centre Ljubljana; Matija Tomšič – University Medical Centre Ljubljana; Fons A.J. van de Loo – Radboud University Medical Center; Valery Bochkov – University of Graz; Toni Petan – Jožef Stefan Institute; Roman Jerala – National Institute of Chemistry
On Demand

OS23.4 - Monocytes traffic extracellular vesicles to damaged muscle and adopt a novel immunophenotype to support muscle regenerationRussell G. Rogers, III, PhD – Smidt Heart Institute, Cedars-Sinai Medical Center; Akbarshakh Akhmerov, M.D. – Smidt Heart Institute, Cedars-Sinai Medical Center; Weixin Liu – Smidt Heart Institute, Cedars-Sinai Medical Center; Lizbeth Sanchez – Smidt Heart Institute, Cedars-Sinai Medical Center; Eduardo Marbán – Smidt Heart Institute, Cedars-Sinai Medical Center
Wednesday, Jul 22
3:31 PM – 3:42 PM

Increased Hematopoietic Extracellular RNAs andVesicles in the Lung during Allergic AirwayResponses Heather H. Pua, MD, PhD – Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center
Disease: Infectious
On Demand

OT08.2 - Vesicles released during Mycobacterium tuberculosis infection: immunomodulatory (glyco)lipids and role in host-pathogen interactionsEmilie Layre – CNRS-Université Paul Sabatier; Emilie Layre – CNRS-Université Paul Sabatier; Pierre Boyer – CNRS-Université Paul Sabatier; Jerome Nigou – CNRS-Université Paul Sabatier
On Demand

OT08.3 - Blood-Based Detection of Tuberculosis using Outer Membrane VesiclesNishal Shah, MS – University of Pennsylvania; Jina Ko, PhD – Massachusetts General Hospital, Wyss Institute at Harvard University; takahiro Yano – University of Pennsylvania; Sruthi Ravimohan – University of Pennsylvania; Greg Bisson – University of Pennsylvania; Harvey Rubin – University of Pennsylvania; David Issadore, MDPhD – Department of Bioengineering, University of Pennsylvania
On Demand

OT08.4 - Mechanisms of innate immune regulation by exosomes released during infection with pathogenic gram-negative bacteriaAdam Fleming – George Mason University; Heather Hobbs – George Mason University; Graham Matulis – George Mason University; Valentin Giroux – George Mason University; Weidong Zhou – Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA; Valerie Calvert – George Mason University; Carolina Salvador-Morales – George Mason University; Nitin Agrawal – Children's National Hospital; Emanuel Petricoin – George Mason University; Rekha Panchal – USAMRIID; Sina Bavari – USAMRIID; Ramin M. Hakami – George Mason University; Ramin M. Hakami – George Mason University
On Demand

OT08.6 - Human pathogenic fungus Candida albicans induces immunomodulatory TGF-β1-transporting vesicles from human immune cellsLuke D. Halder – Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (HKI); Emeraldo Jo – Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (HKI); Mohammad Hasan – Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (HKI); Marta Ferreira-Gomes – Friedrich Schiller University; Thomas Krüger – Leibniz Institute for Natural Product Research and Infection Biology (HKI), Department of Molecular and Applied Microbiology, Jena, Germany; Martin Westermann – University Hospital Jena; Diana Palme – Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (HKI); Günter Rambach – Medical University of Innsbruck; Niklas Beyersdorf – University of Würzburg; Cornelia Speth – Medical University of Innsbruck; Ilse Jacobsen – Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (HKI); Olaf Kniemeyer – Leibniz Institute for Natural Product Research and Infection Biology (HKI), Department of Molecular and Applied Microbiology, Jena, Germany; Berit Jungnickel – Friedrich Schiller University; Peter Zipfel – Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (HKI); Christine Skerka – Leibniz Institute for Natural Product Research and Infection Biology – Hans Knöll Institute (HKI)
On Demand

OT11.1 - Unbiased quantitative proteomic analysis identifies novel cellular components specifically incorporated into endogenous EV subtypes, HIV-1 particles and virus-modified EVslorena Martin-Jaular – INSERM U932, Institut Curie, PSL Research university; Nathalie Nevo – INSERM U932, Institut Curie, PSL Research university; mercedes tkach – INSERM U932, Institut Curie, PSL Research university; mabel jouve – CNRS UMR3215, Institut Curie, PSL Research university; Florent Dingli – Institut Curie, PSL Research University, Laboratoire de Spectrométrie de Masse Protéomique; damarys loew – Institut Curie, PSL Research University, Laboratoire de Spectrométrie de Masse Protéomique; Kenneth Witwer – Department of Molecular and Comparative Pathobiology and Department of Neurology, The Johns Hopkins University School of Medicine; matias ostrowski – Instituto INBIRS, Universidad de Buenos Aires-CONICET; georg borner – Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry,; Clotilde Théry, MD PhD – INSERM U932, Institut Curie, PSL Research university; lorena Martin-Jaular – INSERM U932, Institut Curie, PSL Research university
On Demand

OT11.2 - The encephalomyocarditis virus Leader modulates autophagic pathways to promote the release of virions inside extracellular vesiclesKyra AY Defourny, Msc – Dept. Biomolecular Health Sciences, Fac. Veterinary Medicine, Utrecht University, The Netherlands; Susanne G. Van der grein – Dept. Biomolecular Health Sciences, Fac. Veterinary Medicine, Utrecht University, The Netherlands; Huib rabouw – Dept. Biomolecular Health Sciences, Fac. Veterinary Medicine, Utrecht University, The Netherlands; Frank J.M. Van Kuppeveld – Dept. Biomolecular Health Sciences, Fac. Veterinary Medicine, Utrecht University, The Netherlands; Esther Nolte-'t Hoen – Dept. Biomolecular Health Sciences, Fac. Veterinary Medicine, Utrecht University
On Demand

OT11.3 - ZIKV induced DEFA1B blocks ZIKV adsorption and retard cell cycle by regulating ORC1 expressionShuang Li – Institute of Blood Transfusion, Peking Union Medical College; Shilin Li – Institute of Blood Transfusion, Chinese Academy of Medical Sciences Peking Union Medical College; Limin Chen – Institute of Blood Transfusion, Chinese Academy of Medical Sciences Peking Union Medical College
On Demand

OT11.4 - Extracellular vesicles mediate bacterial-immune cell interactions during respiratory viral-bacterial co-infectionsSidney Lane – University of Pittsburgh; Matthew Hendricks – University of Washington; Jennifer Bomberger – University of Pittsburgh
On Demand

OT11.5 - Using machine learning with neuronal EV target proteins and clinical data to predict cognitive impairment in HIV infectionLynn Pulliam, PhD – University of California, San Francisco; Michael Liston, MS – Veteran Affairs; bing Sun, M.D., MD PhD – NCIRE; Jared Narvid – UCSF
On Demand

OT11.6 - Who comes out first: Extracellular Vesicles (EV) or Viruses?Fatah Kashanchi, PhD – Laboratory of Molecular Virology, School of Systems Biology, George Mason University, Manassas, VA; Yuriy Kim – George Mason University; Daniel Pinto – George Mason University; Gifty Mensah – George Mason University; Maria Cowen – George Mason University; James Erickson – George Mason University; Michelle Pleet – George Mason University; Catherine DeMarino – George Mason University; Renaud Mahieux – Superieure de Lyon, Université
On Demand

OF12.5 - Bacterial membrane vesicles (MVs) — a bacterial innate defense system against viral infectionXiaomei Yan, PhD – Xiamen University; Qian Niu – Xiamen University; Ye Tian – Xiamen University
On Demand

OS20.3 - Salivary exosomes – Carrier of High Risk Human Papillomavirus Causing Oropharyngeal Cancerchamindie punyadeera, PhD – QUT; chamindie punyadeera, PhD – QUT; kai tang – QUT; Liz Kenny – RBWH; Brett Hughes – RBWH; sarj vasani – RBWH; Yunxia Wan – QUT
On Demand

OS22.2 - Extracellular vesicles containing host restrictive factor IFITM3 inhibited Zika virus infection of fetuses in pregnant mice through trans-placenta deliveryAllen Z. Wu, PhD – Nanjing University; Allen Z. Wu, PhD – Nanjing University
Disease: Neurological
On Demand

OT07.1 - Alzheimer's disease biomarkers in plasma extracellular vesicles of neuronal origin correlate with brain pathology in miceFrancheska Delgado-Peraza – Laboratory of Clinical Investigation, National Institutes of Aging; Erez Eitan – NeuroDex; Carlos J. Nogueras-Ortiz, PhD – Laboratory of Clinical Investigation, National Institutes of Aging; Dong Liu – Department of otorhinolaryngology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University; Mark P Mattson – Johns Hopkins School of Medicine; Nigel Greig – National Institute on Aging/National Institutes of Health; Dimitrios Kapogiannis – Laboratory of Clinical Investigation, National Institutes of Aging
On Demand

OT07.2 - Exosomal ceramide mediates neurotoxicity of Amyloid beta (Aβ) in Alzheimer’s disease.Ahmed Elsherbini – University of Kentucky; Simone Crivelli – University of Kentucky; Alexander Kirov – Augusta University; Michael Dinkins – Augusta University; Zhihui Zhu – University of Kentucky; Haiyan Qin – University of Kentucky; Sanjib Karki – University of Kentucky; Priyanka Tripathi – University of Kentucky; Erhard Bieberich – University of Kentucky
On Demand

OT07.4 - Blood-derived extracellular vesicles in Multiple Sclerosis: the effects of Particulate Matter exposureLuca Ferrari, PhD – EPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano; Mirjam Hoxha – Epiget Lab Dipartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy; Simona Iodice – EPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano; Federica Rota – Epiget Lab Dipartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy; Jacopo Mariani, BS – EPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano; Giulia Mallucci – IRCCS Fondazione Mondino, Department of Neurology and Neurorehabilitation, Multiple Sclerosis Unit, Pavia, Italy; Roberto Bergamaschi – IRCCS Fondazione Mondino, Department of Neurology and Neurorehabilitation, Multiple Sclerosis Unit, Pavia, Italy; Valentina Bollati – EPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano
On Demand

OT07.6 - Plasma neuronal and astrocyte-derived exosomes serve as biomarkers of neurodegeneration and systemic bioenergetic effects in male Cynomolgus monkeys self-administrating oxycodoneAshish Kumar – Wake Forest Baptist Medical Center; Yixin Su – Wake Forest Baptist Medical Center; David Soto-Pantoja – Wake Forest Baptist Medical Center; Jingyun Lee – Wake Forest Baptist Medical Center; Ravi Singh – Wake Forest Baptist Medical Center; Cristina Furdui – Wake Forest Baptist Medical Center; Michael Nader – Wake Forest Baptist Medical Center; Gagan Deep, PhD – Wake Forest Baptist Medical Center; Gagan Deep, PhD – Wake Forest Baptist Medical Center
On Demand

OT10.1 - Intranasal administration of neural stem cells-derived extracellular vesicles promotes neurogenesis and reduces neuroinflammation and amyloid plaques in a mouse model of Alzheimer’s diseaseLeelavathi N. Madhu – Institute of Regenerative medicine, College of Medicine, Texas A&M University; Raghavendra Upadhya, PhD – Institute of Regenerative Medicine, College of Medicine, Texas A&M University; Sahithi Attaluri, M Pharm – Institute of Regenerative Medicine, College of Medicine, Texas A&M University; Maheedhar Kodali, PhD – Institute for Regenerative Medicine, College of Medicine, Texas A&M University; Laila Melissari – Institute for Regenerative Medicine, College of Medicine, Texas A&M University; Andrew Vogel – Institute of Regenerative Medicine, College of Medicine, Texas A&M University; Bing Shuai – Institute of Regenerative Medicine, College of Medicine, Texas A&M University; Ashok K Shetty – Institute of Regenerative Medicine, College of Medicine, Texas A&M University
On Demand

OS19.1 - Extracellular vesicle associated microRNA-29a elicits microglial activation and synaptodendritic injury with chronic methamphetamine exposureDalia Moore – University of Nebraska Medical Center; Alexander Clark – Creighton University; Farah Shahjin – UNMC; Niming Wu – University of Nebraska Medical Center; Subhash Chand – University of Nebraska Medical Center; katherine odegaard – University of Nebraska Medical Center; austin Gowen – University of Nebraska Medical Center; Rick Bevins, MDPhD – UNIVERSITY OF NEBRASKA AT LINCOLN; Gurudutt Pendyala, MDPhD – University of Nebraska Medical Center; Howard Fox, MDPHD – University of Nebraska Medical Center; Sowmya V. Yelamanchili, PhD – Department of Anesthesiology; Sowmya V. Yelamanchili, PhD – Department of Anesthesiology
On Demand

OS19.2 - Blood-borne and brain-derived ectosomes/microparticles in morphine-induced anti-nociceptive toleranceDeepa Ruhela, MD PhD – University of Maryland School of Medicine; Veena Bhopale, MD PhD – University of Maryland School of Medicine; Ming Yang, MD – University of Maryland School of Medicine; Kevin Yu, MD PhD – University of Maryland School of Medicine; Eric Weintraub, MD – University of Maryland School of Medicine; Aaron Greenblatt, MD – University of Maryland School of Medicine; Stephen R. Thom, MD, PhD – University of Maryland School of Medicine; Stephen R. Thom, MD, PhD – University of Maryland School of Medicine
On Demand

OS19.3 - EVs are a conveyor of toxic dipeptide repeat proteins in C9orf72 ALS/FTD modelsMaria Elena Cicardi – Thomas Jefferson University; Davide Trotti – Thomas jefferson University
On Demand

OS19.5 - Association of neuronal-derived extracellular vesicles cargo with cognitive decline in late middle lifeErden Eren, PhD – National Institute on Aging, NIH; Jack Hunt – Wisconsin Alzheimer’s Disease Research Center, University of Wisconsin; Michelle Shardell – University of Maryland; Sahil Chawla – National Institute on Aging, NIH; Joyce Tran – National Institute on Aging, NIH; Jeffrey Gu – NIA/NIH; Nick Vogt – Wisconsin Alzheimer’s Disease Research Center, University of Wisconsin; Sterling Johnson – Wisconsin Alzheimer’s Disease Research Center, University of Wisconsin; Barbara B. Bendlin – Wisconsin Alzheimer’s Disease Research Center, University of Wisconsin; Dimitrios Kapogiannis – Laboratory of Clinical Investigation, National Institutes of Aging
On Demand

OS19.6 - Extracellular Vesicle Release from the Choroid Plexus Visualized Using ExoMap-2 MiceChristie D. Fowler, PhD – University of California, Irvine; Valeria Lallai, MD PhD – University of California, Irvine; Francis Fordjour, MD PhD – Johns Hopkins University; Lane Christenson, MDPhD – University of Kansas Medical Center; Stephen Gould, MD PhD – Johns Hopkins University
On Demand

OS21.6 - Astrocyte-derived EV-mediated blood-brain barrier disruptionShilpa Buch, PhD – University of Nebraska Medical Center; Ke Liao – University of Nebraska Medical Center; Susmita Sil – University of Nebraska Medical Center; Fang Niu – University of Nebraska Medical Center; Guoku Hu, PhD – University of Nebraska Medical Center
On Demand

OS25.2 - Fibroblast Growth Factor 2-mediated Regulation of Neuronal Exosome Release Depends on VAMP3/cellubrevin in Hippocampal Neurons.Thomas Koeglsperger, Dr. – German Center for Neurodegenerative Diseases (DZNE); Thomas Koeglsperger, Dr. – German Center for Neurodegenerative Diseases (DZNE); Rohit Kumar – German Center for Neurodegenerative Diseases (DZNE); Qilin Tang – German Center for Neurodegenerative Diseases (DZNE); Stephan A. Müller – German Center for Neurodegenerative Diseases (DZNE); Pan Gao – German Center for Neurodegenerative Diseases (DZNE); Mahlstedt Diana – German Center for Neurodegenerative Diseases (DZNE); Yi Tan – German Center for Neurodegenerative Diseases (DZNE); Klingl Andreas – Department of Biology, Ludwig Maximilian University, Munich; Kai Bötzel – Department of Neurology, Ludwig Maximilian University, Munich; Stefan F. Lichtenthaler – German Center for Neurodegenerative Diseases (DZNE); Günter Höglinger – German Center for Neurodegenerative Diseases (DZNE)
On Demand

OS25.3 - The well-chaperoned extracellular vesicle: their presence in neuropathologiesXiaoli Yu – University of Colorado Denver, Anschutz Medical Campus, Department of Neurosurgery; Anthony Fringuello – University of Colorado Denver, Anschutz Medical Campus, Department of Neurosurgery; Steven G. Griffiths – X0S0ME; Brooke Metzger – Illinois College; Michael W. Graner – University of Colorado Anschutz Medical Campus
On Demand

OS29.1 - A specific non-coding RNA in extracellular vesicles from induced neuronal cells and epigenetic regulation of neurotransmissionEllen Tedford – Cambridge University; Norhidayah Badya – U of Leeds; Conor Laing – University of Leeds; Glenn McConkey, PhD – University of Leeds; Glenn McConkey, PhD – University of Leeds
On Demand

OS29.4 - Human CD4+ T regulatory-derived extracellular vesicles and associated microRNAs: role in cell-to-cell communication and involvement in the loss of immune tolerance during multiple sclerosisSilvia Garavelli – Laboratorio di Immunologia, Istituto di Endocrinologia e Oncologia Sperimentale, Consiglio Nazionale delle Ricerche (IEOS-CNR), Naples, Italy; Claudio Procaccini – Laboratorio di Immunologia, Istituto di Endocrinologia e Oncologia Sperimentale, Consiglio Nazionale delle Ricerche (IEOS-CNR), Naples, Italy; Alessandra Colamatteo – Treg Cell Laboratory, Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università Degli Studi di Napoli "Federico II", Naples, Italy; Fortunata Carbone – Laboratorio di Immunologia, Istituto di Endocrinologia e Oncologia Sperimentale, Consiglio Nazionale delle Ricerche (IEOS-CNR), Naples, Italy; Elena Tagliabue – IRCCS MultiMedica; Donatella Carpi – Joint Research Centre, Ispra, Varese, Italy; Laura Cantone – EPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano; Valentina Bollati – EPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano; Ilaria Giusti – Department of Life Health and Environmental Sciences, University of L'Aquila, Italy; Vincenza Dolo – Department of Life, Health and Environmental Sciences, University of L'Aquila; Sarah Grossi – Universita' degli Studi dell’Insubria, Dipartimento di biotecnologie e scienze della vita, Varese, Italy; Paola Campomenosi – Universita' degli Studi dell’Insubria, Dipartimento di biotecnologie e scienze della vita, Varese, Italy; Dario Di Silvestre – Istituto di Tecnologie Biomediche, Consiglio Nazionale delle Ricerche (ITB-CNR), 20090 Segrate, Milano, Italy; Pierluigi Mauri – Istituto di Tecnologie Biomediche, Consiglio Nazionale delle Ricerche (ITB-CNR), 20090 Segrate, Milano, Italy; Annibale Puca – IRCCS MultiMedica; Fabio Buttari – Unit of Neurology and Unit of Neurorehabilitation, IRCCS Istituto Neurologico Mediterraneo (INM) Neuromed, Pozzilli, IS, Italy; Diego Centonze – Unit of Neurology and Unit of Neurorehabilitation, IRCCS Istituto Neurologico Mediterraneo (INM) Neuromed, Pozzilli, IS, Italy; Veronica De Rosa – Laboratorio di Immunologia, Istituto di Endocrinologia e Oncologia Sperimentale, Consiglio Nazionale delle Ricerche (IEOS-CNR), Naples, Italy; Giuseppe Matarese – Treg Cell Laboratory, Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università Degli Studi di Napoli "Federico II", Naples, Italy; Paola de Candia – IRCCS MultiMedica; Paola de Candia – IRCCS MultiMedica
On Demand

OS29.5 - Revealing the proteome of Brain Derived Extracellular Vesicles isolated from human Amyotrophic Lateral Sclerosis post-mortem tissues.Natasha Vassileff – The Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria, Australia.; Laura J Vella – The Florey Institute of Neuroscience and Mental Health, University of Melbourne; Harinda Rajapaksha – La Trobe Institute for Molecular Science; Mitch Shambrook – Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, Australia; Amirmohammad Nasiri Kenari, PhD student – Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, VIC, Australia; Jacky Chan – The Florey Institute of Neuroscience and Mental Health; Catriona McLean – The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, Australia.; Andrew F Hill – Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University; Lesley Cheng – Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University
Monday, Jul 20
12:01 PM – 12:25 PM

Plenary Session: EVs in Neurological DiseasesHollis T. Cline – The Scripps Research Institute
ISEV Current EVents
Tuesday, Jul 21
11:00 AM – 12:00 PM

Head over Heels about EVsPhil W. Askenase, MD – yale university
Thursday, Jul 23
11:00 AM – 1:00 PM

Emerging Trends in EV Research in HIV, NeuroAIDS & Drug Abuse
Thursday, Jul 23
6:00 PM – 7:00 PM

Standardisation and Rigor Task Force for Bacterial EVs
Thursday, Jul 30
6:00 PM – 7:00 PM

Student Network on EVs (SNEV)
Outreach
On Demand

OS26.1 - HEVI NZ: A Hub for Extracellular Vesicle Investigations in New Zealand supports research and educationCherie Blenkiron, BSc, PhD – The University of Auckland; Colin L. Hisey, PhD – The University of Auckland; Vanessa Chang – The University of Auckland; Lawrence W. Chamley – The University of Auckland
On Demand

OS26.2 - EMBO practical course ‘Extracellular Vesicles: From Biology to Biomedical Applications’Esther Nolte-'t Hoen – Dept. Biomolecular Health Sciences, Fac. Veterinary Medicine, Utrecht University; Guillaume van Niel, PhD – Institute of Psychiatry and Neurosciences of Paris U-1266 INSERM; Cecilia Lässer, PhD – Krefting Research Centre, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg; An Hendrix – Laboratory of Experimental Cancer Research, Department of Human Structure and Repair, Ghent University, Belgium; Cancer Research Institute Ghent, Belgium
On Demand

OS26.3 - 1st Lugano ExoDay - technical challenges in exosome research. First extracellular vesicles workshop in the Southern SwitzerlandDaniele D'Arrigo, MD – Regenerative Medicine Technologies Lab, RMTL-EOC; Carolina Balbi, PhD – Cardiocentro Ticino; Giona Pedrioli, MSc – Laboratory for Biomedical Neurosciences, LBN-EOC; Elena Vacchi, MSc – Laboratory for Biomedical Neurosciences, LBN-EOC; Vanessa Biemmi – Cardiocentro Ticino; Giorgia Melli – Laboratory for Biomedical Neurosciences, LBN-EOC; Giuseppe Vassalli – Cardiocentro Ticino; Matteo Moretti – Regenerative Medicine Technologies Lab, RMTL-EOC; Paolo Paganetti – Laboratory for Biomedical Neurosciences, LBN-EOC; Lucio Barile – Cardiocentro Ticino
On Demand

OS26.5 - The role of core facilities and emerging technologies in maximizing rigor and reproducibility of EV quantification and characterization and following MISEV guidelinesRachel M. DeRita, PhD – University of Pennsylvania; Andrew Hoffman, DVM, DVSc – University of Pennsylvania School of Veterinary Medicine
RNA
On Demand

OT01.3 - The addition of a size exclusion chromatography step to various urinary extracellular vesicle concentrating methods reveals differences in the small RNA profileJenni Karttunen, PhD – Department of Veterinary Medicine, University of Cambridge; Sarah E. Stewart – Institute of Metabolic Science, University of Cambridge, Cambridge, UK; Andrew Grant – Department of Veterinary Medicine, University of Cambridge, Cambridge, UK; Lajos Kalmar – Department of Veterinary Medicine, University of Cambridge, Cambridge, UK; Fiona E Karet Frankl – Department of Medical Genetics, University of Cambridge, Cambridge, UK; Tim Williams – Department of Veterinary Medicine, University of Cambridge, Cambridge, UK
On Demand

OT02.6 - Desmoglein 2 enhances squamous cell carcinoma tumor development through extracellular vesicles in an IL-8/miR-146a-dependent mechanismJoseph P. Flemming – Thomas Jefferson University; Mohammed Haque – Thomas Jefferson University; Brianna L. Hill – Thomas Jefferson University; James Wahl – UNMC; Kenneth Tsai – Moffitt Cancer Center; Peter Wermuth – TJU; Andrew Overmiller – Thomas Jefferson University; My Mahoney – Thomas Jefferson University
On Demand

OT03.4 - MiRNA-192 and -432 depleted c-kit+ progenitor cell exosomes promotes the proliferation, migration of mesenchymal stem cells and regulates inflammationHyun-Ji Park, PhD – Emory University; Jessica R. Hoffman – Emory University; Michael Davis – Emory University
On Demand

OT04.5 - Uncovering novel genes regulating EV-mediated functional RNA transfer using a CRISPR/Cas9-based reporter systemOlivier G. de Jong, PhD – Laboratory of Clinical Chemistry and Hematology, UMC Utrecht, The Netherlands; Daniel E. Murphy, MSc – Laboratory of Clinical Chemistry and Hematology, UMC Utrecht; Imre Mäger – Department of Paediatrics, University of Oxford; Eduard Willms – La Trobe University; Sander A.A Kooijmans, PhD – CDL Research, University Medical Center Utrecht, The Netherlands; Jacco van Rheenen – Department of Molecular Pathology, Oncode Institute, Netherlands Cancer Institute; Raymond M. Schiffelers – Laboratory of Clinical Chemistry and Hematology, UMC Utrecht, The Netherlands; Samir El-Andaloussi – Department of Laboratory Medicine, Clinical Research Center, Karolinska Institutet; Matthew J.A. Wood – Department of Paediatrics, University of Oxford; Pieter Vader – Laboratory of Clinical Chemistry and Hematology, UMC Utrecht; Department of Experimental Cardiology, UMC Utrecht, The Netherlands
On Demand

OT09.2 - Fragmentation of extracellular ribosomes and tRNAs shapes the extracellular RNAomeJuan P. Tosar, PhD – Universidad de la República, Uruguay; Juan P. Tosar, PhD – Universidad de la República, Uruguay; Mercedes Segovia – Laboratory of 9 Immunoregulation and Inflammation, Institut Pasteur de Montevideo, Uruguay.; Fabiana Gámbaro – Functional Genomics Unit, Institut Pasteur de Montevideo, Uruguay; Yasutoshi Akiyama – Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, USA. Department of Medicine, Harvard Medical School, Boston, MA, USA.; Pablo Fagúndez – Analytical Biochemistry Unit. Nuclear Research Center. Faculty of Science. Universidad de la República, Uruguay.; Bruno Costa – Analytical Biochemistry Unit. Nuclear Research Center. Faculty of Science. Universidad de la República, Uruguay.; Tania Possi – Functional Genomics Unit, Institut Pasteur de Montevideo, Uruguay; Marcelo Hill – Laboratory of Immunoregulation and Inflammation, Institut Pasteur de Montevideo, Uruguay.; Pavel Ivanov – Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, USA. Department of Medicine, Harvard Medical School, Boston, MA, USA; Alfonso Cayota – Functional Genomics Unit, Institut Pasteur de Montevideo, Uruguay
On Demand

OT09.3 - CD47 interactions with exportin-1 regulate targeting of m7G-capped RNAs to extracellular vesiclesSukbir Kaur, PhD – National Cancer Institutes; Alejandra Cavazos Saldana – Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, USA; Abdel G. Elkahloun – Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, USA; Jennifer D. Petersen, PhD – Section on Integrative Biophysics, Division of Basic and Translational Biophysics, Eunice Kennedy-Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, USA; Anush Arakelyan – Section on Intercellular Interactions, Division of Basic and Translational Biophysics, Eunice Kennedy-Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda,; Satya P. Singh – Inflammation Biology Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, USA.; Lisa M Jenkins – Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, USA; Bethany Kuo – Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, USA; Bianca Reginauld – Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, USA; David G Jordan – Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, USA; Andy D Tran – Confocal Microscopy Core Facility, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, USA; Weiwei Wu – Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, USA; Joshua Zimmerberg – Section on Integrative Biophysics, Division of Basic and Translational Biophysics, Eunice Kennedy-Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, USA; Leonid Margolis – Section on Intercellular Interactions, Division of Basic and Translational Biophysics, Eunice Kennedy-Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, USA; David D. Roberts – Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, USA
On Demand

OT09.6 - Translation initiation factor eIF4E reprograms the vesiculation of cancer cellsEsterina D'Asti – University of Montreal; Biljana Culjkovic-Kraljacic – University of Montreal; Héloïse Chassé – University of Montreal; Jadwiga Gasiorek – University of Montreal; Gavin Morris – University of Montreal; Katherine Borden – University of Montreal
On Demand

OT10.4 - Epigenetic regulation of fetal hypoplastic lungs by amniotic fluid stem cell derived extracellular vesiclesLina Antounians, MSc – The Hospital for Sick Children; Huayun Hou – The Hospital for Sick Children; Cadia Chan – The Hospital for Sick Children; Michael Wilson – The Hospital for Sick Children; Augusto Zani – The Hospital for Sick Children; Augusto Zani – The Hospital for Sick Children
On Demand

OT10.6 - lncRNA EPHA6-1 in IFNβ-induced small extracellular vesicles promotes cytotoxicity of NK cells by acting as a ceRNA for hsa-miR-4485 to up-regulate NKp46 expressionShuang Li – Institute of Blood Transfusion, Peking Union Medical College; Anjing Zhu – Institute of Blood Transfusion, Chinese Academy of Medical Sciences Peking Union Medical College; Shilin Li – Institute of Blood Transfusion, Chinese Academy of Medical Sciences Peking Union Medical College; Limin Chen – Institute of Blood Transfusion, Chinese Academy of Medical Sciences Peking Union Medical College
On Demand

OF14.2 - Y-RNA subtype ratios in plasma extracellular vesicles are cell type specific and are candidate biomarkers for inflammatory diseasesTom Driedonks, PhD – Dept. Molecular & Comparative Pathobiology, Johns Hopkins School of Medicine; Sanne Mol – Dept. Biochemistry & Cell Biology, Fac. Veterinary Medicine, Utrecht University, The Netherlands; Sanne de Bruin – Dept. Intensive Care, Amsterdam University Medical Centers, location AMC, Amsterdam, The Netherlands; Anna-Linda Peters – Dept. Anesthesiology, University Medical Center Utrecht, Utrecht, The Netherlands; Xiaogang Zhang – Dept. Biochemistry & Cell Biology, Fac. Veterinary Medicine, Utrecht University, The Netherlands; Marthe Lindenbergh – Dept. Biochemistry & Cell Biology, Fac. Veterinary Medicine, Utrecht University, The Netherlands; Boukje Beuger – Dept. of Blood Cell Research, Sanquin Research, and Landsteiner Laboratory, Amsterdam University Medical Centers, Location AMC, Amsterdam, The Netherlands; Anne-Marieke Stalborch – Molecular Cell Biology lab, Dept. of Molecular and Cellular Hemostasis, Sanquin Research, and Landsteiner Laboratory, Amsterdam University Medical Centers, Location AMC, Amsterdam, The Netherlands; Thom Spaan – Dept. of Infectious Diseases & Immunity, Division of Virology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands; Esther de Jong – Dept. Experimental Immunology, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, The Netherlands; Erhard van der Vries – Dept. of Infectious Diseases & Immunity, Division of Virology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands; Coert Margadant – Molecular Cell Biology lab, Dept. of Molecular and Cellular Hemostasis, Sanquin Research, and Landsteiner Laboratory, Amsterdam University Medical Centers, Location AMC, Amsterdam, The Netherlands; Robin van Bruggen – Dept. of Blood Cell Research, Sanquin Research, and Landsteiner Laboratory, Amsterdam University Medical Centers, Location AMC, Amsterdam, The Netherlands; Alexander Vlaar – Dept. Intensive Care, Amsterdam University Medical Centers, location AMC, Amsterdam, The Netherlands; Tom Groot Kormelink – Dept. Experimental Immunology, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, The Netherlands; Esther Nolte-'t Hoen – Dept. Biomolecular Health Sciences, Fac. Veterinary Medicine, Utrecht University
On Demand

OF14.3 - Mining public EV Small RNA-seq data with miREV – Insights into potential reference transcripts and abundant miRNAsAlex Hildebrandt – Division of Animal Physiology and Immunology, Technical University of Munich, Freising, Germany; Benedikt Kirchner, MSc – Division of Animal Physiology and Immunology, Technical University of Munich, Freising, Germany; Esther Nolte-'t Hoen – Dept. Biomolecular Health Sciences, Fac. Veterinary Medicine, Utrecht University; Michael W. Pfaffl, PhD – Division of Animal Physiology and Immunology, Technical University of Munich, Freising, Germany
On Demand

OF14.4 - Presence of vault RNA and proteins indicates contamination of extracellular vesicle preparations with vault particlesXinming Liu, MSc(Res) – The University of Sheffield; Daniel Lambert – The University of Sheffield; Stuart Hunt – The University of Sheffield; Stuart Hunt – The University of Sheffield
On Demand

OF14.5 - Staphylococcus aureus secrete immunomodulatory RNA and DNA via extracellular vesiclesBlanca V. Rodriguez, MS – Duke University; Meta Kuehn – Duke University
On Demand

OF14.6 - Urinary extracellular vesicles transcriptome in diabetic kidney diseaseOm Dwivedi – Institute for Molecular Medicine Finland FIMM, University of Helsinki, Finland; Maija Puhka – Institute for Molecular Medicine Finland FIMM, University of Helsinki, Finland; Karina A. Barreiro, MSc – Institute for Molecular Medicine Finland FIMM, University of Helsinki, Finland; erkka valo – Folkhälsan Institute of Genetics, Folkhälsan Research Center, Helsinki, Finland; Harry Holthofer – Institute for Molecular Medicine Finland FIMM, University of Helsinki, Finland; per-henrik Groop – Abdominal Center Nephrology, University of Helsinki and Helsinki University Hospital, Finland; Carol Forsblom – Folkhälsan Institute of Genetics, Folkhälsan Research Center, Helsinki, Finland; tiinamaija tuomi – Hospital District of Helsinki and Uusimaa (HUS), Helsinki, Finland; Leif Groop – Institute for Molecular Medicine Finland FIMM, University of Helsinki, Finland
On Demand

OF15.6 - RNA nanoparticles as EV displaying ligands for specific cancer targeting and efficient RNAi delivery in vivoZhefeng Li, PhD – College of Pharmacy, The Ohio State University; Fengmei Pi, PhD – ExonanoRNA; Zhen Zheng – Center for RNA Nanobiotechnology and Nanomedicine; College of Pharmacy; Comprehensive Cancer Center; Dorothy M. Davis Heart and Lung Research Institute; College of Medicine. The Ohio State University; Peixuan Guo – Center for RNA Nanobiotechnology and Nanomedicine; College of Pharmacy; Comprehensive Cancer Center; Dorothy M. Davis Heart and Lung Research Institute; College of Medicine. The Ohio State University
On Demand

OF16.4 - Whole-Transcriptomic Profiling of Circulating Small Extracellular Vesicles Derived RNAs for Early Detection of Colorectal Carcinoma and AdenomaLi Min, PhD – Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.; Shengtao Zhu – Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.; Xiang Liu – Echo Biotech Co., Ltd, Beijing, China.; Da Qin – Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.; Qingdong Guo – Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.; Rui Wei – Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.; Libo Zhao – Echo Biotech Co., Ltd, Beijing, China.; Guanyi Kong – Echo Biotech Co., Ltd, Beijing, China.; Shutian Zhang – Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.; Shutian Zhang – Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.
On Demand

OF16.5 - RNA Signatures from Blood and Urine EVs Display Tissue-Lineage from Prostate Cancer PatientsNavneet Dogra, PhD – Department of Genetics and Genomic Sciences, Department of Pathology, Icahn School of Medicine, Mount Sinai; Navneet Dogra, PhD – Department of Genetics and Genomic Sciences, Department of Pathology, Icahn School of Medicine, Mount Sinai; Mehmet Ahsen – Icahn School of Medicine at Mount Sinai; Tina Chen – Icahn School of Medicine at Mount Sinai; Reena Olsen – Icahn School of Medicine at Mount Sinai; Dan Han – Icahn School of Medicine at Mount Sinai; Stacey M. Gifford – IBM; Benjamin Wunsch – IBM; Rachel Weil – Icahn School of Medicine at Mount Sinai; Melissa Smith – Icahn School of Medicine at Mount Sinai; Joshua Smith – IBM; Sungchel Kim – IBM; Kamala Bhatt – Icahn School of Medicine at Mount Sinai; Sujit Nair – Icahn School of Medicine at Mount Sinai; Bojan Losic, MDPhD – Icahn School of Medicine at Mount Sinai; Robert Sebra – Icahn School of Medicine at Mount Sinai; Adam Margolin – Icahn School of Medicine at Mount Sinai; Carlos Cordon-Cardo – Icahn School of Medicine at Mount Sinai; Ashutosh Tewari – Icahn School of Medicine at Mount Sinai; GUSTAVO Stolovitzky – Icahn School of Medicine at Mount Sinai
On Demand

OS19.1 - Extracellular vesicle associated microRNA-29a elicits microglial activation and synaptodendritic injury with chronic methamphetamine exposureDalia Moore – University of Nebraska Medical Center; Alexander Clark – Creighton University; Farah Shahjin – UNMC; Niming Wu – University of Nebraska Medical Center; Subhash Chand – University of Nebraska Medical Center; katherine odegaard – University of Nebraska Medical Center; austin Gowen – University of Nebraska Medical Center; Rick Bevins, MDPhD – UNIVERSITY OF NEBRASKA AT LINCOLN; Gurudutt Pendyala, MDPhD – University of Nebraska Medical Center; Howard Fox, MDPHD – University of Nebraska Medical Center; Sowmya V. Yelamanchili, PhD – Department of Anesthesiology; Sowmya V. Yelamanchili, PhD – Department of Anesthesiology
On Demand

OS22.6 - Sequence-specific RNA trafficking to Extracellular Vesicles is conserved across cell typesAndreia M. Silva, PhD – AstraZeneca R&D; Olga Shatnyeva – Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca; Elisa Lázaro-Ibáñez, PhD – Advanced Drug Delivery, BioPharmaceuticals R&D, AstraZeneca; Molly Stevens – Department of Materials, Department of Bioengineering and Institute for Biomedical Engineering, Imperial College London; Department of Medical Biochemistry and Biophysics, Karolinska Institutet; Niek Dekker – Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca
On Demand

OS25.4 - Methamphetamine Use Disorder Uniquely Plasma Extracellular Vesicle MiRNA ExpressionUrsula S. Sandau, PhD – Oregon Health and Science University; Erika Duggan – Scintillon Institute; Xiao Shi – VA Portland Health Care System; Oregon Health and Science University; Tracy Swanson – VA Portland Health Care System; Oregon Health and Science University; Marilyn Huckans – VA Portland Health Care System; Methamphetamine Abuse Research Center; Sierra Smith – Oregon Health and Science University; Jennifer Loftis – VA Portland Health Care System; Methamphetamine Abuse Reaseach System; aaron Janowsky – VA Portland Health Care System; Methamphetamine Abuse Reaseach System; Oregon Health and Science University; John Nolan – Scintillon Institute; Julie A. Saugstad – Oregon Health and Science University
On Demand

OS27.6 - MiR-20a regulates exogenous CD82 expression on proliferation, invasion, migration and angiogenesis of gastric cancerTingting guo – Zhengzhou University
On Demand

OS29.1 - A specific non-coding RNA in extracellular vesicles from induced neuronal cells and epigenetic regulation of neurotransmissionEllen Tedford – Cambridge University; Norhidayah Badya – U of Leeds; Conor Laing – University of Leeds; Glenn McConkey, PhD – University of Leeds; Glenn McConkey, PhD – University of Leeds
On Demand

OS29.4 - Human CD4+ T regulatory-derived extracellular vesicles and associated microRNAs: role in cell-to-cell communication and involvement in the loss of immune tolerance during multiple sclerosisSilvia Garavelli – Laboratorio di Immunologia, Istituto di Endocrinologia e Oncologia Sperimentale, Consiglio Nazionale delle Ricerche (IEOS-CNR), Naples, Italy; Claudio Procaccini – Laboratorio di Immunologia, Istituto di Endocrinologia e Oncologia Sperimentale, Consiglio Nazionale delle Ricerche (IEOS-CNR), Naples, Italy; Alessandra Colamatteo – Treg Cell Laboratory, Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università Degli Studi di Napoli "Federico II", Naples, Italy; Fortunata Carbone – Laboratorio di Immunologia, Istituto di Endocrinologia e Oncologia Sperimentale, Consiglio Nazionale delle Ricerche (IEOS-CNR), Naples, Italy; Elena Tagliabue – IRCCS MultiMedica; Donatella Carpi – Joint Research Centre, Ispra, Varese, Italy; Laura Cantone – EPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano; Valentina Bollati – EPIGET LAB, Department of Clinical Sciences and Community Health, Università degli Studi di Milano; Ilaria Giusti – Department of Life Health and Environmental Sciences, University of L'Aquila, Italy; Vincenza Dolo – Department of Life, Health and Environmental Sciences, University of L'Aquila; Sarah Grossi – Universita' degli Studi dell’Insubria, Dipartimento di biotecnologie e scienze della vita, Varese, Italy; Paola Campomenosi – Universita' degli Studi dell’Insubria, Dipartimento di biotecnologie e scienze della vita, Varese, Italy; Dario Di Silvestre – Istituto di Tecnologie Biomediche, Consiglio Nazionale delle Ricerche (ITB-CNR), 20090 Segrate, Milano, Italy; Pierluigi Mauri – Istituto di Tecnologie Biomediche, Consiglio Nazionale delle Ricerche (ITB-CNR), 20090 Segrate, Milano, Italy; Annibale Puca – IRCCS MultiMedica; Fabio Buttari – Unit of Neurology and Unit of Neurorehabilitation, IRCCS Istituto Neurologico Mediterraneo (INM) Neuromed, Pozzilli, IS, Italy; Diego Centonze – Unit of Neurology and Unit of Neurorehabilitation, IRCCS Istituto Neurologico Mediterraneo (INM) Neuromed, Pozzilli, IS, Italy; Veronica De Rosa – Laboratorio di Immunologia, Istituto di Endocrinologia e Oncologia Sperimentale, Consiglio Nazionale delle Ricerche (IEOS-CNR), Naples, Italy; Giuseppe Matarese – Treg Cell Laboratory, Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università Degli Studi di Napoli "Federico II", Naples, Italy; Paola de Candia – IRCCS MultiMedica; Paola de Candia – IRCCS MultiMedica
Tuesday, Jul 21
7:02 PM – 7:13 PM

EV nucleic acid contentKendall Van Keuren-Jensen – Translational Genomics Research Institute
Tuesday, Jul 21
7:13 PM – 7:25 PM

Bioinformatic analysis of EV RNA dataJoel Rozowsky – Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA
Wednesday, Jul 22
4:05 PM – 4:14 PM

Extracellular biogenesis of extravesicular rRNA- and tRNA-derived fragmentsJuan P. Tosar, PhD – Universidad de la República, Uruguay
Wednesday, Jul 22
3:31 PM – 3:42 PM

Increased Hematopoietic Extracellular RNAs andVesicles in the Lung during Allergic AirwayResponses Heather H. Pua, MD, PhD – Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center
Sponsored Presentations
Monday, Jul 20
1:13 PM – 1:28 PM

Nanoview- Analytical Considerations for Characterizing Disease-Specific EVs Via Surface and Luminal Protein BiomarkersGeorge Daaboul, MDPhD – NanoView Biosciences
Monday, Jul 20
1:13 PM – 1:29 PM

Nano FCM- Nano-Flow Cytometry: A Comprehensive Platform for Extracellular Vesicle AnalysisBen Peacock – The University of Sheffield
Monday, Jul 20
1:13 PM – 1:31 PM

15-minute Platinum Sponsor Presentations- Monday
Monday, Jul 20
1:13 PM – 1:31 PM

Particle Metrix- Latest improvements on fluorescent Nanoparticle Tracking Analysis (f-NTA)Clemens Helmbrecht – Particle Metrix GmbH
Tuesday, Jul 21
4:59 PM – 5:09 PM

10-minute Gold Sponsor Presentations- Tuesday
Tuesday, Jul 21
4:59 PM – 5:09 PM

Beckman- Gold Sponsor Presentation
Tuesday, Jul 21
4:59 PM – 5:09 PM

Luminex- Amnis® ImageStream®X Mk II and Amnis® CellStream® for Small Particle DetectionHaley R. Pugsley, PhD – Luminex Corporation
Tuesday, Jul 21
4:59 PM – 5:09 PM

Malvern Panalytical- Size and concentration of nanoparticlesArianna Biesso
Tuesday, Jul 21
4:59 PM – 5:09 PM

Myriade- Videodrop : Characterize and Count Nanoparticles in a Single Drop and in Real TimePhilippe Garabedian, MBA – Myriade
Tuesday, Jul 21
4:59 PM – 5:09 PM

Streck- Streck RNA Complete BCT™: Maintaining Extracellular Vesicle Count and Circulating RNA Cargo for up to 7 days at Ambient Temperature
Tuesday, Jul 21
7:40 PM – 8:25 PM

15-minute Platinum Sponsor Presentations from Monday
Tuesday, Jul 21
7:45 PM – 8:00 PM

Particle Metrix- Latest improvements on fluorescent Nanoparticle Tracking Analysis (f-NTA)Clemens Helmbrecht – Particle Metrix GmbH
Tuesday, Jul 21
8:00 PM – 8:15 PM

Nano FCM- Nano-Flow Cytometry: A Comprehensive Platform for Extracellular Vesicle AnalysisBen Peacock – The University of Sheffield
Tuesday, Jul 21
8:15 PM – 8:30 PM

Nanoview- Analytical Considerations for Characterizing Disease-Specific EVs Via Surface and Luminal Protein BiomarkersGeorge Daaboul, MDPhD – NanoView Biosciences
Wednesday, Jul 22
12:40 PM – 12:55 PM

15-minute Platinum Sponsor Presentations- Wednesday
Wednesday, Jul 22
12:40 PM – 12:55 PM

FUJIFilm- Characteristics on PS Affinity for Isolation and Detection of Mesenchymal Stem Cell-derived EVsSadamu Ozaki, B.S. – FUJIFILM Wako Pure Chemical Corporation
Wednesday, Jul 22
12:40 PM – 12:55 PM

A New Era In Single Particle Measurement - The Next Generation of TRPS InstrumentsEmma Blundell; Martin Jones
Wednesday, Jul 22
12:40 PM – 12:59 PM

Rooster Bio- Scale-up in Clinical Translation of EVsJon Rowley – RoosterBio Inc
Technologies & Methods
On Demand

OT01.1 - Beyond size-exclusion: dual-mode chromatography improves purity of extracellular vesicles from plasmaJan Van Deun, PhD – University Hospital Erlangen; Ala Jo – Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School; Huiyan Li – Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School; Hsing-Ying Lin – Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School; Ralph Weissleder – Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School; Hyungsoon Im – Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School; Hakho Lee – Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School
On Demand

OT01.2 - Tangential Flow for Analyte Capture of Extracellular VesiclesMehdi Dehghani – Rochester Institute of Technology; Kilean Lucas – University of Rochester; Shayan Gholizadeh – Rochester Institute of Technology; Munther Alsudais – Rochester Institute of Technology; Jonathan Flax – University of Rochester; James McGrath – University of Rochester; Thomas Gaborski – Rochester Institute of Technology
On Demand

OT01.3 - The addition of a size exclusion chromatography step to various urinary extracellular vesicle concentrating methods reveals differences in the small RNA profileJenni Karttunen, PhD – Department of Veterinary Medicine, University of Cambridge; Sarah E. Stewart – Institute of Metabolic Science, University of Cambridge, Cambridge, UK; Andrew Grant – Department of Veterinary Medicine, University of Cambridge, Cambridge, UK; Lajos Kalmar – Department of Veterinary Medicine, University of Cambridge, Cambridge, UK; Fiona E Karet Frankl – Department of Medical Genetics, University of Cambridge, Cambridge, UK; Tim Williams – Department of Veterinary Medicine, University of Cambridge, Cambridge, UK
On Demand

OT01.4 - The use of rEV for the optimization of EV separation and characterization by AF4Lien Lippens, PhD studen – Laboratory of Experimental Cancer Research, Department of Human Structure and Repair, Ghent University, Ghent, Belgium; Edward Geeurickx – Laboratory of Experimental Cancer Research, Department of Human Structure and Repair, Ghent University, Ghent, Belgium; Robin Boiy – Laboratory of Experimental Cancer Research, Department of Human Structure and Repair, Ghent University, Ghent, Belgium; Sarah Deville – Flemish Institute for Technological Research (VITO), Health Unit; Bruno De Geest – Biopharmaceutical Technology Unit, Department of Pharmaceutics, Ghent University, Ghent, Belgium; Olivier de Wever – Laboratory of Experimental Cancer Research, Department of Human Structure and Repair, Ghent University, Belgium; Cancer Research Institute Ghent, Belgium; An Hendrix – Laboratory of Experimental Cancer Research, Department of Human Structure and Repair, Ghent University, Belgium; Cancer Research Institute Ghent, Belgium
On Demand

OT01.5 - Comparative evaluation of EV isolation methods for EV subpopulation analysis in human urine, plasma and cell culture mediaLiang Dong, MD – The Brady Urological Institute, Johns Hopkins University School of Medicine; Richard Zieren, MD – The Brady Urological Institute, Johns Hopkins University School of Medicine; Kengo Horie, MD, PhD – The Brady Urological Institute, Johns Hopkins University School of Medicine; Sarah Amend – The Brady Urological Institute, Johns Hopkins University School of Medicine; Kenneth Pienta – The Brady Urological Institute, Johns Hopkins University School of Medicine
On Demand

OT01.6 - A Capillary-Channeled Polymer (C-CP) Fiber Spin-Down Tip Approach for the Isolation and Biomarker Characterization of Extracellular Vesicles of Ovarian Cancer OriginKaylan K. Jackson – Clemson University; Rhonda R. Powell – Clemson University; Terri F. Bruce, MDPhD – Clemson University; R. Kenneth Marcus – Clemson University
On Demand

OT01.7 - Development and optimization of purification method of exosomes by tangential flow filtration and ion exchange chromatography approachYonatan (Yoni) Levinson – Cell & Gene Therapy R&D, Lonza Inc; Ali Navaei – Cell & Gene Therapy R&D, Lonza Inc; Sandeep Choudhary – Cell & Gene Therapy R&D, Lonza Inc; Yonatan Levinson – Cell & Gene Therapy R&D, Lonza Inc; Senthil Ramaswamy – Cell & Gene Therapy R&D, Lonza Inc
On Demand

OT01.8 - Use of an alternating current electrokinetic microelectrode chip to positively identify oncology, neurology, and infectious disease samples through plasma extracellular vesicle analysisRajaram Krishnan, PhD – Biological Dynamics, Inc.; Jean Lewis, MD PhD – Biological Dynamics, Inc.; David Searson – Biological Dynamics, Inc.; Orlando Perrera – Biological Dynamics, Inc.; Alfred Kinana, MD PhD – Biological Dynamics, Inc.; Heath Balcer, MD PhD – Biological Dynamics, Inc.; Rajaram Krishnan, PhD – Biological Dynamics, Inc.
On Demand

OT04.4 - A bright, versatile reporter for multivesicular body trafficking and exosome secretion and uptakeBong Hwan Sung, MSc, PhD – Department of Cell and Developmental Biology, Vanderbilt University; Ariana von Lersner – Vanderbilt University; Jorje Guerrero – University of Wisconsin-Madison; Evan Krystofiak – Vanderbilt University; David Inmann – University of Wisconsin-Madison; Roxanne Pelletier – Vanderbilt University; Andries Zijlstra – Vanderbilt University Medical Center; Suzanne Ponik – University of Wisconsin-Madison; Alissa Weaver – Department of Cell and Developmental Biology, Vanderbilt University School of Medicine
On Demand

OT04.5 - Uncovering novel genes regulating EV-mediated functional RNA transfer using a CRISPR/Cas9-based reporter systemOlivier G. de Jong, PhD – Laboratory of Clinical Chemistry and Hematology, UMC Utrecht, The Netherlands; Daniel E. Murphy, MSc – Laboratory of Clinical Chemistry and Hematology, UMC Utrecht; Imre Mäger – Department of Paediatrics, University of Oxford; Eduard Willms – La Trobe University; Sander A.A Kooijmans, PhD – CDL Research, University Medical Center Utrecht, The Netherlands; Jacco van Rheenen – Department of Molecular Pathology, Oncode Institute, Netherlands Cancer Institute; Raymond M. Schiffelers – Laboratory of Clinical Chemistry and Hematology, UMC Utrecht, The Netherlands; Samir El-Andaloussi – Department of Laboratory Medicine, Clinical Research Center, Karolinska Institutet; Matthew J.A. Wood – Department of Paediatrics, University of Oxford; Pieter Vader – Laboratory of Clinical Chemistry and Hematology, UMC Utrecht; Department of Experimental Cardiology, UMC Utrecht, The Netherlands
On Demand

OT04.6 - Quantitative characterization of Extracellular Vesicle Uptake and Content Delivery within Mammalians Cellsgregory lavieu, PhD – INSERM U132/Institut Curie; gregory lavieu, PhD – INSERM U132/Institut Curie; emeline Bonsergent – Institut Curie/ Universite de Paris; eleonora grisard – institut Curie; Clotilde Théry, MD PhD – INSERM U932, Institut Curie, PSL Research university
On Demand

OT05.3 - Droplet-based Single Extracellular Vesicle Sequencing for Rare Immune Subtype DiscoveryJina Ko, PhD – Massachusetts General Hospital, Wyss Institute at Harvard University; Yongcheng Wang – Harvard University; David Weitz – Harvard University; Ralph Weissleder – Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School
On Demand

OT05.4 - Advancing extracellular vesicle characterization with quantitative single molecule localization microscopyKathleen Lennon – Beckman Research Institute, City of Hope; Metztli Cisneros – Beckman Research Institute, City of Hope; Adam Maddox – Beckman Research Institute, City of Hope; Devin L. Wakefield – Beckman Research Institute, City of Hope; Matthew Brehove – Beckman Research Institute, City of Hope; Saumya Das – Massachusetts General Hospital, Harvard Medical School; Kendall Van Keuren-Jensen – Translational Genomics Research Institute; Gagandeep Singh – City of Hope; Tijana Jovanovic-Talisman – Beckman Research Institute, City of Hope; Tijana Jovanovic-Talisman – Beckman Research Institute, City of Hope
On Demand

OT05.5 - An Evaluation of Four Orthogonal Single-Particle Analysis PlatformsEmily R. Mallick – Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine; Tanina Arab – Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine; Yiyao Huang, MD – Department of Molecular and Comparative Pathobiology, The John Hopkins University School of Medicine; Zhaohao Liao – Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine; Zezhou Zhao – Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine; Liang Dong, MD – The Brady Urological Institute, Johns Hopkins University School of Medicine; Kenneth Pienta – The Brady Urological Institute, Johns Hopkins University School of Medicine; Michael Paulaitis – The Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine; Kenneth Witwer – Department of Molecular and Comparative Pathobiology and Department of Neurology, The Johns Hopkins University School of Medicine
On Demand

OT05.6 - Analysis of tetraspanin expression and spatial arrangement for EV subpopulations using single particle interferometric reflectance imaging and immunofluorescence.Rachel Mizenko – Department of Biomedical Engineering, University of California, Davis; Alyssa Powell – Department of Biomedical Engineering, University of California, Davis; Randy Carney, PhD – Department of Biomedical Engineering, University of California, Davis
On Demand

OT10.5 - Bottom-up assembly of fully-synthetic extracellular vesiclesOskar Staufer, MA – Max Planck Institute for Medical Research, Department for Cellular Biophysics, Jahnstraße 29, 69120 Heidelberg, Germany; Oskar Staufer, MA – Max Planck Institute for Medical Research, Department for Cellular Biophysics, Jahnstraße 29, 69120 Heidelberg, Germany; Franziska Dietrich – Max Planck Institute for Medical Research, Department for Cellular Biophysics, Jahnstraße 29, 69120 Heidelberg, Germany; Jochen Hernandez – Max Planck Institute for Medical Research, Department for Cellular Biophysics, Jahnstraße 29, 69120 Heidelberg, Germany; Martin Schröter – Max Planck Institute for Medical Research, Department for Cellular Biophysics, Jahnstraße 29, 69120 Heidelberg, Germany; Sebastian Fabritz – Department for Chemical Biology, Max Planck Institute for Medical Research, Jahnstraße 29, 69120 Heidelberg, Germany; Heike Böhm – Max Planck Institute for Medical Research, Department for Cellular Biophysics, Jahnstraße 29, 69120 Heidelberg, Germany; Ilia Platzman – Max Planck Institute for Medical Research, Department for Cellular Biophysics, Jahnstraße 29, 69120 Heidelberg, Germany; Joachim Spatz – Max Planck Institute for Medical Research, Department for Cellular Biophysics, Jahnstraße 29, 69120 Heidelberg, Germany
On Demand

OF12.1 - Development of non-invasive clinically applicable in vivo tracking of extracellular vesicles using magnetic resonance imaging (MRI)Johnny Akers – Visicell Medical; Paola Aguiari – Children's Hospital Los Angeles; Hamsik Soloyan – Children's Hospital Los Angeles; Seda Mkhitaryan – Children's Hospital Los Angeles; Gevorg Karapetyan – Children's Hospital Los Angeles; Laura Perin – Children's Hospital Los Angeles-University of Southern California; Mya Thu – Children's Hospital Los Angeles-University of Southern California; Sargis Sedrakyan, PhD – Children's Hospital Los Angeles-University of Southern California; Sargis Sedrakyan, PhD – Children's Hospital Los Angeles-University of Southern California
On Demand

OF12.7 - In vivo tracking of extracellular vesicles: comparison across radioactive, fluorescence and bioluminescence approachesElisa Lázaro-Ibáñez, PhD – Advanced Drug Delivery, BioPharmaceuticals R&D, AstraZeneca; Farid N. Faruqu – Institute of Pharmaceutical Science, King's College London; Amer Saleh – Clinical Pharmacology & Safety Sciences, Biopharmaceuticals R&D, AstraZeneca; Andreia M. Silva, PhD – AstraZeneca R&D; Khuloud Al-Jamal – Institute of Pharmaceutical Science, King’s College London; Niek Dekker – Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca
On Demand

OF13.1 - Analysis of extracellular vesicles by size exclusion chromatography coupled with on-line fluorescence detection and microfluidic resistive pulse sensingDiana Kitka – Research Centre for Natural Sciences; Mihaly Judith – Research Centre for Natural Sciences; Jean-Luc Fraikin, PhD – Spectradyne; Zoltan Varga, PhD – Biological Nanochemistry Research Group, Institute of Materials and Environmental Chemistry, Research Center for Natural Sciences, Budapest, Hungary; Zoltan Varga, PhD – Biological Nanochemistry Research Group, Institute of Materials and Environmental Chemistry, Research Center for Natural Sciences, Budapest, Hungary
On Demand

OF13.2 - The CONAN assay: purity grade and concentration of EV microliter formulations by colloidal nanoplasmonics.Paolo Bergese – Consorzio Interuniversitario Nazionale per la Scienza e la Tecnologia dei Materiali, Florence, Italy; Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy and Consorzio Sistemi a Grande Interfase, Department of Chemistry, University of Florence, Sesto Fiorentino, Italy; Paolo Bergese – Consorzio Interuniversitario Nazionale per la Scienza e la Tecnologia dei Materiali, Florence, Italy; Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy and Consorzio Sistemi a Grande Interfase, Department of Chemistry, University of Florence, Sesto Fiorentino, Italy; Andrea Zendrini, PhD – Department of Animal Science, Food and Nutrition-Università Cattolica del Sacro Cuore, Piacenza, Italy; Lucia Paolini – Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy, and Consorzio Sistemi a Grande Interfase, Department of Chemistry, University of Florence, Sesto Fiorentino, Italy; Sara Busatto – Consorzio Sistemi a Grande Interfase, Department of Chemistry, University of Florence, Sesto Fiorentino, Italy and Department of Transplantation, Mayo Clinic, Jacksonville, FL, United States; Annalisa Radeghieri – Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy and Consorzio Sistemi a Grande Interfase, Department of Chemistry, University of Florence, Sesto Fiorentino, Italy; Miriam Romano – Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy and Consorzio Sistemi a Grande Interfase, Department of Chemistry, University of Florence, Sesto Fiorentino, Italy; Marca H.M. Wauben – Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands; Martijn J.C. van Herwijnen, PhD – Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands; Peter Nejsum – Department of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus, Q12 Denmark; Anne Borup – Department of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus, Q12 Denmark; Andrea Ridolfi – Consorzio Sistemi a Grande Interfase, Department of Chemistry, University of Florence, Sesto Fiorentino, Italy ; Istituto per lo Studio dei Materiali Nanostrutturati (CNR-ISMN), Bologna, Italy and Department of Chemistry, University of Florence, Sesto Fiorentino, Italy; Costanza Montis – Consorzio Sistemi a Grande Interfase, Department of Chemistry, University of Florence, Sesto Fiorentino, Italy and Department of Chemistry, University of Florence, Sesto Fiorentino, Italy
On Demand

OF13.4 - Membrane-sensing peptides for extracellular vesicles analysisMarina Cretich – Consiglio Nazionale delle Ricerche (CNR); Istituto di Scienze e Tecnologie Chimiche (SCITEC); Roberto Frigerio – Consiglio Nazionale delle Ricerche (CNR); Istituto di Scienze e Tecnologie Chimiche (SCITEC); Alessandro Strada – Consiglio Nazionale delle Ricerche (CNR); Istituto di Scienze e Tecnologie Chimiche (SCITEC); Greta Bergamaschi – Consiglio Nazionale delle Ricerche (CNR); Istituto di Scienze e Tecnologie Chimiche (SCITEC); Marcella Chiari – Consiglio Nazionale delle Ricerche (CNR); Istituto di Scienze e tecnologie Chimiche (SCITEC); Alessandro Gori – Consiglio Nazionale delle Ricerche (CNR); Istituto di Scienze e tecnologie Chimiche (SCITEC)
On Demand

OF13.5 - High-resolution size-based profiling and morphological analysis of extracellular vesicles by scanning electron microscopySara Cavallaro, MS – KTH Royal Institute of Technology; Federico Pevere – Uppsala University; Petra Hååg – Karolinska Institute; Kristina Viktorsson – Karolinska Institute; Rolf Lewensohn – Karolinska Institute; Jan Linnros – KTH Royal Institute of Technology; Apurba Dev – Uppsala University
On Demand

OF13.6 - Detailed Characterization of how different extracellular vesicles isolation methods results in different amount of Periostin protein association.Carolina Balbi, PhD – Cardiocentro Ticino; Edoardo Lazzarini – Cardiocentro Ticino; Emanuel Fertig – Victor Babes National Institute of Pathology; Mihaela Gherghiceanu – Victor Babes National Institute of Pathology; Lucio Barile – Cardiocentro Ticino; Giuseppe Vassalli – Cardiocentro Ticino
On Demand

OF14.3 - Mining public EV Small RNA-seq data with miREV – Insights into potential reference transcripts and abundant miRNAsAlex Hildebrandt – Division of Animal Physiology and Immunology, Technical University of Munich, Freising, Germany; Benedikt Kirchner, MSc – Division of Animal Physiology and Immunology, Technical University of Munich, Freising, Germany; Esther Nolte-'t Hoen – Dept. Biomolecular Health Sciences, Fac. Veterinary Medicine, Utrecht University; Michael W. Pfaffl, PhD – Division of Animal Physiology and Immunology, Technical University of Munich, Freising, Germany
On Demand

OF15.1 - Engineering extracellular vesicles for targeted delivery of Cas9 to T cellsDevin M. Stranford – Northwestern University; Lacy Simons – Northwestern University; Judd F. Hultquist – Northwestern University; Joshua N. Leonard – Northwestern University
On Demand

OF15.2 - Exosomal AAVs in Myocardial Repair: Escaping Neutralizing Antibody and Enhancing DeliveryMarta Adamiak, PhD – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Shweta Lodha, BA – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Morad Asadi – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Yaxuan Liang – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Cherrie Sherman – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Erik Kohlbrenner – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Dongtak Jeong – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Delaine Ceholski – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Navneet Dogra, PhD – Department of Genetics and Genomic Sciences, Department of Pathology, Icahn School of Medicine, Mount Sinai; Nicole Dubois – Department of Developmental and Regenerative Biology, Mindich Child Health and Development Institute, Black Family Stem Cell Institute, Icahn School of Medicine, Mount Sinai; Roger Hajjar – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai; Susmita Sahoo – Cardiovascular Research Center, Icahn School of Medicine, Mount Sinai
On Demand

OF15.6 - RNA nanoparticles as EV displaying ligands for specific cancer targeting and efficient RNAi delivery in vivoZhefeng Li, PhD – College of Pharmacy, The Ohio State University; Fengmei Pi, PhD – ExonanoRNA; Zhen Zheng – Center for RNA Nanobiotechnology and Nanomedicine; College of Pharmacy; Comprehensive Cancer Center; Dorothy M. Davis Heart and Lung Research Institute; College of Medicine. The Ohio State University; Peixuan Guo – Center for RNA Nanobiotechnology and Nanomedicine; College of Pharmacy; Comprehensive Cancer Center; Dorothy M. Davis Heart and Lung Research Institute; College of Medicine. The Ohio State University
On Demand

OF18.5 - Three-dimensional culture models to elucidate exosomal biologyKathleen M. McAndrews – UT MD Anderson Cancer Center; Fei Xiao – UT MD Anderson Cancer Center; Valerie LeBleu – UT MD Anderson Cancer Center; Raghu Kalluri – Department of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center
On Demand

OS19.6 - Extracellular Vesicle Release from the Choroid Plexus Visualized Using ExoMap-2 MiceChristie D. Fowler, PhD – University of California, Irvine; Valeria Lallai, MD PhD – University of California, Irvine; Francis Fordjour, MD PhD – Johns Hopkins University; Lane Christenson, MDPhD – University of Kansas Medical Center; Stephen Gould, MD PhD – Johns Hopkins University
On Demand

OS22.1 - Single particle Raman spectroscopy: an emerging tool to quantify composition of engineered extracellular vesiclesRandy Carney, PhD – Department of Biomedical Engineering, University of California, Davis; Randy Carney, PhD – Department of Biomedical Engineering, University of California, Davis; Marissa Taub – University of California, Davis; Rachel Mizenko – Department of Biomedical Engineering, University of California, Davis; Dina Pham – Department of Biomedical Engineering, University of California, Davis
On Demand

OS22.3 - Engineering extracellular vesicles with altered cellular tropism for targeted payload delivery in vivoMonique Kauke, PhD – Codiak BioSciences; Nikki Ross – Codiak BioSciences; Dalia Burzyn – Codiak BioSciences; Shelly Martin – Codiak BioSciences; Ke Xu – Codiak BioSciences; Nuruddeen Lewis – Codiak BioSciences; Charan Leng – Codiak BioSciences; Su Chul Jang – Codiak BioSciences; Stephanie Yu – Codiak BioSciences; Kevin Dooley – Codiak BioSciences; Sriram Sathyanarayanan – Codiak BioSciences; Jonathan Finn – Codiak BioSciences
On Demand

OS22.4 - A novel method for the delivery of cell-free therapy to fetuses with congenital anomalies: a proof of principle studyLina Antounians, MSc – The Hospital for Sick Children; Lina Antounians, MSc – The Hospital for Sick Children; Louise Montalva – The Hospital for Sick Children; Gabriele Raffler – The Hospital for Sick Children; Maria Sole Gaffi – The Hospital for Sick Children; Augusto Zani – The Hospital for Sick Children; Augusto Zani – The Hospital for Sick Children
On Demand

OS22.5 - Microalgae as a novel and renewable bioresource of extracellular vesicleAntonella Bongiovanni, PhD – Institute for Research and Biomedical Innovation (IRIB) - National Research Council (CNR); Antonella Bongiovanni, PhD – Institute for Research and Biomedical Innovation (IRIB) - National Research Council (CNR); Giorgia Adamo – Institute for Research and Biomedical Innovation (IRIB) - National Research Council (CNR); Sabrina Picciotto – Institute for Research and Biomedical Innovation (IRIB) - National Research Council (CNR); University of Palermo; David Fierli – Institute of Technology Sligo (ITSligo); Maria Elena Barone – Institute of Technology Sligo (ITSligo); Anita Aranyos – Institute of Technology Sligo (ITSligo); Rachel Parkes – Institute of Technology Sligo (ITSligo); Svenja Morsbach – Max-Planck Institute for Polymer Research; Samuele Raccosta – Institute of Biophysics (IBF) - National Research Council (CNR); Darja Božič – University of Ljubljana; Antonella Cusimano – Institute for Research and Biomedical Innovation (IRIB) - National Research Council (CNR); Christopher Stanly – Institute of Biosciences and BioResources (IBBR) - National Research Council (CNR); Daniele P Romancino – Institute for Research and Biomedical Innovation (IRIB) - National Research Council (CNR); Rita Carrotta – Institute of Biophysics (IBF) - National Research Council (CNR); Carolina Paganini, MS – ETH Zurich; Umberto Capasso Palmiero – ETH Zurich; Vincenzo Martorana – Institute of Biophysics (IBF) - National Research Council (CNR); Rosina Noto – Institute of Biophysics (IBF) - National Research Council (CNR); Giovanna L Liguori – Institute of Genetics and Biophysics (IGB) - National Research Council (CNR); Annamaria Kisslinger – Institute of Experimental Endocrinology and Oncology (IEOS); Laura Corcuera – Zabala Innovation Consulting; Elia Di Schiavi – Institute of Biosciences and BioResources (IBBR) - National Research Council (CNR); Veronika Kralj-Iglič – University of Ljubljana; Ales Iglič – University of Ljubljana; Katharina Landfester – Max-Planck Institute for Polymer Research; Paolo Arosio – ETH Zurich; Gabriella Pocsfalvi – Institute of Biosciences and BioResources (IBBR) - National Research Council (CNR); Mauro Manno – Institute of Biophysics (IBF) - National Research Council (CNR); Nicolas Touzet – Institute of Technology Sligo (ITSligo)
On Demand

OS24.1 - Scaling-up the manufacturing of well-characterized mesenchymal stromal cell-derived extracellular vesicles for biomedical applicationsAna Fernandes-Platzgummer – Department of Bioengineering and iBB – Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal; Sara Rosa – Department of Bioengineering and iBB – Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal; Ricardo Silva – Department of Bioengineering and iBB – Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal; Raquel MS Cunha, PhD – Instituto Superior Técnico, University of Lisbon; Miguel Almeida Fuzeta, MSc – Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal; Cecília Calado – Instituto Superior de Engenharia de Lisboa; Carla Carvalho – Department of Bioengineering and iBB – Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal; Joaquim Cabral – Department of Bioengineering and iBB – Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal; Ana Azevedo – Department of Bioengineering and iBB – Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal; Cláudia Silva – Department of Bioengineering and iBB – Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal
On Demand

OS24.2 - Ultrasensitive Protein Detection for Quantification of Extracellular Vesicles in Human Biofluids Enables Comparison of Isolation TechniquesDmitry Ter-Ovanesyan, PhD – Wyss Institute; Maia Norman, B.S. – Wyss Institute; Wendy Trieu – Wyss Institute; Roey Lazarovits – Wyss Institute; George Church – Wyss Institute; David Walt – Wyss Institute
On Demand

OS24.3 - Combinatorial antibody microarray profiling of intra- and extravesicular proteins in colorectal cancer cell line extracellular vesiclesRosalie martel, MEng – McGill University; Molly L. shen – McGill University; Philippe Decorwin-Martin, M.Eng – McGill University; Lucile Alexandre – McGill University; lorenna oliveira – McGill University; Andy Ng – McGill University; David Juncker, MDPhD – McGill University
On Demand

OS24.4 - Characterization of EVs using orthogonal techniques identifies discrete EV populations from a mouse dendritic cell lineBryce Killingsworth – Laboratory of Pathology, National Cancer Institute, National Institutes of Health; Timothy Traynor – Laboratory of Pathology, National Cancer Institute, National Institutes of Health; Joshua A. Welsh – Laboratory of Pathology, National Cancer Institute, National Institute of Health; Aleksandra Dakic – Laboratory of Pathology, National Cancer Institute, National Institutes of Health; Jason Savage – Laboratory of Pathology, National Cancer Institute, National Institutes of Health; Kevin Camphausen – Radiation Oncology Branch, National Cancer Institute, National Institutes of Health; Kenneth Aldape – Laboratory of Pathology, National Cancer Institute, National Institutes of Health; Jennifer Jones – Laboratory of Pathology, National Cancer Institute, National Institutes of Health
On Demand

OS24.5 - Hybrid plasmonic biomaterial nanofilter scaffold for cancer EV diagnostics based on surface-enhanced Raman scattering (SERS)Hanna J. Koster – Department of Biomedical Engineering, University of California, Davis; Tatu Rojalin, MD PhD – Department of Biomedical Engineering, University of California, Davis; Juanjuan Liu – Department of Bioengineering, McGill University; Sebastian Wachmann Hogiu, MD PhD – Department of Bioengineering, McGill University; Randy Carney, PhD – Department of Biomedical Engineering, University of California, Davis
On Demand

OS24.6 - Laser Trapping Raman spectroscopy (LTRS) of single vesicles can distinguish extent of lipoprotein contaminationMarissa Taub – University of California, Davis; Rachel Mizenko – Department of Biomedical Engineering, University of California, Davis; Dina Pham – Department of Biomedical Engineering, University of California, Davis; Randy Carney, PhD – Department of Biomedical Engineering, University of California, Davis
On Demand

OS26.5 - The role of core facilities and emerging technologies in maximizing rigor and reproducibility of EV quantification and characterization and following MISEV guidelinesRachel M. DeRita, PhD – University of Pennsylvania; Andrew Hoffman, DVM, DVSc – University of Pennsylvania School of Veterinary Medicine
On Demand

OS26.6 - Program to assess the rigor and reproducibility of extracellular vesicle-derived analytes for cancer detectionMatthew Young, PhD – National Cancer Institute; Sudhir Srivastava – National Cancer Institute
On Demand

OS27.2 - Detecting Tumor-Associated Membrane Receptors on Extracellular Vesicles via immuno-PCR with Affibody-DNA-ConjugatesChristiane Stiller, PhD – Uppsala University; Petra Hååg – Karolinska Institute; Elizabeth Paz Gomero – KTH Royal Institute of Technology; Vasiliki Arapi – Karolinska Institute; Kristina Viktorsson – Karolinska Institute; Rolf Lewensohn – Karolinska Institute; Amelie E. Karlström – KTH Royal Institute of Technology
On Demand

OS27.3 - Heterogeneity in EV Cargo Expression Measured by Single Vesicle Flow CytometryJohn Nolan – Scintillon Institute; Erika Duggan – Scintillon Institute
On Demand

OS27.7 - Streamlined detection and quantification of plasma extracellular vesicles and their protein cargo by high-performance nanoscale flow cytometry and label-free mass spectrometrySamuel Tassi Yunga, MD, PhD – Knight Cancer Institute, Oregon Health & Science University; Randall Armstrong – OHSU; Austin Gower – Knight Cancer Institute, Oregon Health & Science University; Meghan Fitzgerald – Knight Cancer Institute, Oregon Health & Science University; Matthew Chang – Knight Cancer Institute, Oregon Health & Science University; Ashok Reddy – Proteomics Shared Resources, OHSU; Mark Flory – OHSU; Owen McCarty – Department of Biomedical Engineering, Oregon Health & Science University; Owen McCarty – Department of Biomedical Engineering, Oregon Health & Science University
On Demand

OS28.1 - Absolute quantification of Extracellular vesicles in vivo by a sensitive bioluminescence system.Dhanu Gupta, MSc – Department of Laboratory Medicine, Karolinska Institutet, Sweden; Xiuming Liang – Clinical Research Center, Department for Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden; Joel Nordin – Clinical Research Center, Department for Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden; Samir El-Andaloussi – Department of Laboratory Medicine, Clinical Research Center, Karolinska Institutet
On Demand

OS28.2 - Biofunctional peptide-modified extracellular vesicles for cell targeting, macropinocytosis induction, and effective intracellular deliveryIkuhiko Nakase, PhD – Department of Biological Science, Graduate School of Science, Osaka Prefecture University; Ikuhiko Nakase, PhD – Department of Biological Science, Graduate School of Science, Osaka Prefecture University
On Demand

OS29.6 - Separation of microglial EVs from human brain-derived EVsTanina Arab, PhD – Department of Molecular and Comparative Pathobiology, Johns Hopkins School of Medicine, Johns Hopkins University, Baltimore, MD, USA; Yiyao Huang – Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine; Vasiliki Machairaki – Department of Neurology, Johns Hopkins University School of Medicine; Juan Troncoso – Department of Neurology, Johns Hopkins University School of Medicine; Olga Pletniková – Department of Pathology, Johns Hopkins University School of Medicine; Kenneth Witwer – Department of Molecular and Comparative Pathobiology and Department of Neurology, The Johns Hopkins University School of Medicine
Monday, Jul 20
12:54 PM – 1:03 PM

Towards reference intervals of extracellular vesicles in human plasma by flow cytometryBo Li – Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University; Edwin van der Pol – Department of Clinical Chemistry, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Vesicle Observation Center, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Department of Biomedical Engineering and Physics, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Lei Zheng – Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China; Rienk nieuwland – Department of Clinical Chemistry, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands, Vesicle Observation Center, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
Monday, Jul 20
1:53 PM – 2:04 PM

ISEV guidelines on EV studies (MISEV2018) and standardization initiativesClotilde Théry, MD PhD – INSERM U932, Institut Curie, PSL Research university; Kenneth Witwer – Department of Molecular and Comparative Pathobiology and Department of Neurology, The Johns Hopkins University School of Medicine
Monday, Jul 20
2:04 PM – 2:16 PM

Flow CytometryJohn Nolan – Scintillon Institute; Kenneth Witwer – Department of Molecular and Comparative Pathobiology and Department of Neurology, The Johns Hopkins University School of Medicine
Monday, Jul 20
2:16 PM – 2:26 PM

Urinary Extracellular Vesicles-perspectives and challenges for biomedical research and clinical utilizationAlicia Llorente – Dept. of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.; Elena S. Martens-Uzunova – Erasmus Medical Center; Kenneth Witwer – Department of Molecular and Comparative Pathobiology and Department of Neurology, The Johns Hopkins University School of Medicine
Monday, Jul 20
2:57 PM – 3:08 PM

EV separation methods: variable recovery and specificity requires transparencyAn Hendrix – Laboratory of Experimental Cancer Research, Department of Human Structure and Repair, Ghent University, Belgium; Cancer Research Institute Ghent, Belgium
Monday, Jul 20
3:18 PM – 3:31 PM

EV imaging TEMGuillaume van Niel, PhD – Institute of Psychiatry and Neurosciences of Paris U-1266 INSERM
Tuesday, Jul 21
5:33 PM – 5:44 PM

Size and concentration determination of extracellular vesicles with flow cytometry, nanoparticle tracking analysis, and resistive pulse sensingEdwin van der Pol – Department of Clinical Chemistry, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Vesicle Observation Center, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Department of Biomedical Engineering and Physics, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
Tuesday, Jul 21
5:58 PM – 6:09 PM

Capture TechnologyMar Valés Gómez – Spanish National Centre for Biotechnology (CNB-CSIC)
Tuesday, Jul 21
6:47 PM – 7:02 PM

Proteomics and Bioinformatic analysis of EV protein contentSuresh Mathivanan – La Trobe University
Tuesday, Jul 21
7:02 PM – 7:13 PM

EV nucleic acid contentKendall Van Keuren-Jensen – Translational Genomics Research Institute
Tuesday, Jul 21
7:13 PM – 7:25 PM

Bioinformatic analysis of EV RNA dataJoel Rozowsky – Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA
Wednesday, Jul 22
11:01 AM – 11:26 AM

Contributions of Cryo-Electron Microscopy to the EV fieldAlain Brisson – Universite de Bordeaux
Wednesday, Jul 22
11:38 AM – 12:04 PM

Microfluidics for the Isolation of Extracellular VesiclesShannon Stott – Harvard Medical School
Wednesday, Jul 22
12:14 PM – 12:29 PM

IntroductionKenneth Witwer – Department of Molecular and Comparative Pathobiology and Department of Neurology, The Johns Hopkins University School of Medicine
Wednesday, Jul 22
12:15 PM – 12:30 PM

Genetically encoded probes provide insight into extracellular vesicle cargo release in cellsBhagyashree Joshi – University Medical Center Groningen; Marit de Beer – Postdoctoral researcher; Ben N G Giepmans – Associate Professor; Inge S Zuhorn – Associate Professor