MP03-19: REGIONAL DIFFERENCES AND THE IMPACT ON STONE-RELATED QUALITY OF LIFE: RESULTS FROM THE NORTH AMERICAN STONE QUALITY OF LIFE CONSORTIUM

Luke Limfueco, Francis Jefferson, Shlomi Tapiero, Zhamshid Okhunov, Roshan Patel, Jodi Antonelli, Necole Streeper, Kristina Penniston, Stephen Nakada, Sri Sivalingam, Davis Viprakasit, Timothy Averch, Thomas Chi, Vincent Bird, Vernon Pais, Roger Sur, Sero Andonian, Noah Canvasser, Ben Chew, Jaime Landman, Ralph Clayman

Introduction: Urolithiasis is associated with a decreased health-related quality of life. The Wisconsin Stone Quality of Life (WISQOL) questionnaire is a validated instrument to evaluate Stone-Related Quality of Life (SRQOL) in patients with kidney stones. Our objective was to assess the correlation between geographical location and SRQOL in the North American Stone Quality of Life Consortium.

Methods: A total of 2308 patients from 14 institutions who completed the WISQOL questionnaire were categorized into 4 populations by their geographical locations: West (W), Midwest (MW), South (S), and Northeast (NE). The WISQOL questionnaire is a 28-question survey that quantifies SRQOL using a Likert-type scale according to the following domains: social function, emotional function, stone-related impact, and vitality (total score range 0-140). Demographic and clinical data, as well as WISQOL domain and total scores were analyzed.

Results: Populations did not differ by age, gender, number of comorbidities, nor age at enrollment. In group W, more patients had stones at the time they completed the WISQOL, and their body mass index was lower compared to other groups (Table 1). Upon univariate analysis, population W exhibited a lower SRQOL within each domain and a lower overall SRQOL compared to the other geographical populations (p<0.001) (Table 2). After controlling for statistically significant covariates through multivariate analysis, residing in the West was a significant independent predictor of a lower SRQOL (p<0.001). Residing in the Northeast was a significant independent predictor for a higher SRQOL (p=0.017) compared to the rest of the cohort.

Conclusions: Geographical region was independently associated with SRQOL. Patients residing in the West exhibited a significantly lower SRQOL compared to other populations whereas patients residing in the Northeast had a significantly higher SRQOL. Source of

Funding: none