It is well known that adopting the Hydrophilic-Lipophilic Difference and Net Average Curvature (HLD-NAC) models provide opportunities for easily predicting oil/water systems with minimal interfacial tension between phases. It has also been demonstrated how minimal interfacial tension leads to effective cleaning systems when the soil is well defined. Two additional parameters that also impact cleaning are substrate wetting and surfactant monomer diffusion to the cleaning solution/soil interface. This discussion focuses on how utilization of the concepts behind HLD-NAC can be combined with the latter two to provide an efficient and effective hard surface cleaner.