Presentation Description / Session Abstract: Everyone likes an anniversary, and it is 50 years since the paper by Ariela Pomerance and John Whitney (Cardiovascular Research, Volume 4, Issue 1, January 1970, Pages 61–66) first reported the comparative aspects of myxomatous mitral valve disease (MMVD) in the dog and human. Over the following 50 years we have come a long way with this disease, but how close are we, or our medical colleagues, to understanding the fundamental biology and cause of MMVD? In this lecture I will review 50 years of research examining how our insight into MMVD has developed and changed and how close we are, or not, to identifying the cause of the single most important cardiovascular disease in canine medicine.
Learning Objectives:
Understand the historical context behind understanding of canine myxomatous mitral valve disease.
Have a clear understanding of the fundamental biology of canine myxomatous mitral valve disease.
Have an appreciation of the potential direction in canine myxomatous mitral valve disease research.