Expression of the cGAMP Transporter SLC19A1 Is Altered in Systemic Lupus Erythematosus Jeong Min Yu, MD – Cedars-Sinai Medical Center
9:00 AM – 11:00 AM ET
Genome-wide DNA Methylation Analysis in Lupus Keratinocytes Identifies Differential Methylation of Genes That Regulate Apoptosis Grace Hile, MD – University of Michigan
9:00 AM – 11:00 AM ET
Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-induced Lupus Model Gantsetseg Tumurkhuu, PhD – Cedars-Sinai Medical Center
9:00 AM – 11:00 AM ET
CXCL13 Neutralization Reduces Neuropsychiatric Manifestations in MRL/lpr Mice Michelle Huang, MS – Albert Einstein College of Medicine
9:00 AM – 11:00 AM ET
An SLE-linked ITGAM Gene Variant Changes Mac-1 Structure, Signaling, and Surface Expression and Enhances IFNg Production and Antigen Presentation by B Cells Joseph L. Blake – UAB
9:00 AM – 11:00 AM ET
RNA Externalized by Neutrophil Extracellular Traps Promotes Inflammatory Pathways in Endothelial Cells Luz Blanco, PhD – NIAMS, National Institute of Health
9:00 AM – 11:00 AM ET
Targeted Sequencing Revealed Novel Candidate Genetic Contributions to Lupus Nephritis in a Cohort of Swedish Patients with Systemic Lupus Erythematosus Sule Yavuz, MD – Uppsala University
9:00 AM – 11:00 AM ET
Endogenous Interferon-β and Low IL-4R on Transitional B Cells Promotes Lupus Nephritis Fatima AlDuraibi, MD – University of Alabama at Birmingham
9:00 AM – 11:00 AM ET
Role of Protein Tyrosine Phosphatase 1B (PTP1B) in Endothelial-to-Mesenchymal Transition (EndoMT) Promoted by Inflammation: Implications for SLE Jorge Romo-Tena, MD – NIH / INNSZ
9:00 AM – 11:00 AM ET
SLAMF7 and CD38 on NK Cells Represent Potential New Therapeutic Targets for Systemic Lupus Erythematosus Morgane Humbel, MS – University of Lausanne
9:00 AM – 11:00 AM ET
Exhausted pSTAT5-IFNα Signaling Pathways in SLE Patients Are Correlated with Age-associated B Cells and Disease Activity Samantha Slight-Webb, PhD – Oklahoma Medical Research Foundation
9:00 AM – 11:00 AM ET
Contraction of the Stool Taxa Clostridia Is Associated with the Development of Clinical Disease Among Anti-Ro+ Mothers of Children with Neonatal Lupus Robert Clancy, PhD – NYU Grossman School of Medicine
9:00 AM – 11:00 AM ET
Tired T-Cells and Monocytes with Malaise: Investigating the Links Between Cellular Iron Deficiency and Mitochondrial Dysfunction in Systemic Lupus Erythematosus Chris Wincup, MBChB, MRCP – University College London
9:00 AM – 11:00 AM ET
CCL3L3–null Status May Predispose to Systemic Lupus Erythematosus and Non-scarring Alopecia Eunyoung Lee, MD – Seoul National University Hospital
9:00 AM – 11:00 AM ET
Investigating the Differences in ANA Specificities Between Asymptomatic and Symptomatic ANA+ Individuals Carolina Munoz-Grajales, MD – University of Toronto-UHN
9:00 AM – 11:00 AM ET
Towards a Glucocorticoid Exposure Signature in SLE: Effects of Type I Interferon Melissa Northcott, MBBS, FRACP – Monash University
9:00 AM – 11:00 AM ET
Local Genetic Ancestry Associations with Clinical Features of Systemic Lupus Erythematosus Olivia Solomon, MPH – University of California, Berkeley
9:00 AM – 11:00 AM ET
The Minor Protective Allele at rs1876453 Is Associated with Increased Age of Onset of Systemic Lupus Erythematosus Ani Oganesyan, BA – University Of Colorado School Of Medicine
9:00 AM – 11:00 AM ET
Exposure to Topical Antimicrobials Reduces Inflammatory Gene Expression in Cutaneous Lupus Lesional Skin Sirisha Sirobhushanam, PhD – University of Michigan
9:00 AM – 11:00 AM ET
Genetic Associations and Polygenic Risk Assessment in Incomplete Lupus Erythematosus Matt Slief, BS – Oklahoma Medical Research Foundation
9:00 AM – 11:00 AM ET
Longitudinal Study of Acute SLE Flare Reveals Dynamic Changes in Multiple Immune Cell Subsets Kieran Manion, PhD – Toronto Western Hospital
9:00 AM – 11:00 AM ET
SLE Patients Stratify into Distinct Clusters Based on Their Peripheral Blood Immunologic Phenotype During Acute Flare Kieran Manion, PhD – Toronto Western Hospital
9:00 AM – 11:00 AM ET
Type I Interferon Inhibits Glucocorticoid-Induced Leucine Zipper (GILZ) Expression and Upregulation by Glucocorticoids Wendy Dankers – Monash University