Genetics, genomics and proteomics
Functional genomics describes the process of integrating genomic DNA sequencing data with other types of genome-scale data to elucidate the effects of genes, proteins and genetic variation. This is undertaken by analyzing the results of genome-scale DNA sequencing in the context of other types of genomic sequencing, such as the sequencing of RNA or chromatin, in populations of purified cells or single cells, to inform clinical decision-making. This approach is particularly valuable in the research of rheumatic diseases, where the development of diseases depends on environmental contributions in the setting of genetic risk factors. The goal of this session is to provide an overview of ongoing research in the rapidly expanding field of functional genomics, with a specific emphasis on potential applications to precision medicine.