Metabolic bone disease
Richard Loeser, Jr, MD
University of North Carolina
Lynda Bonewald, PhD
Indiana University
The osteocyte is a terminally differentiated osteoblast that lies within the bone matrix and controls the translation of mechanical and metabolic signals to the bone surface and cartilage for remodeling or modeling. In addition, the osteocyte has endocrine functions including maintaining the level of phosphate in the circulation, through the release of FGF23. These are just a few of the functions of this amazing cell that will be discussed in detail by faculty.
