Visiting Professor of Surgery
Harvard Medical School
Carl J. Hauser MD, FACS, FCCM, Beth Israel Deaconess Medical Center, Boston MA.
Dr. Hauser went to NYU School of Medicine. He trained in Surgery and Surgical Critical Care at Harbor/UCLA Medical Center under Dr. William C. Shoemaker. Starting as an Instructor of Surgery at USC and an Associate Professor at University of Mississippi, he rose to Tenured Professor of Surgery at New Jersey Medical School. He later moved to BIDMC in Boston where he was Trauma Medical Director from 2010-2019. The major focus of Dr. Hauser's lab is inflammation biology. His work on mitochondrial 'danger signals', or DAMPs, as initiators of inflammation after injury (Nature, 2010) has been cited over 2500 times and is widely held to have been a key conceptual advance in inflammation research. The Hauser Lab currently centers on molecular aspects of inflammation after injury and the susceptibility to infection that injury incurs. Key aspects of this problem under investigation include neutrophil signaling, chemokine biology, cell calcium flux signaling, and regulation of immune cell function. We have shown that susceptibility to infection incurred by injury is in great measure due to immune cell exposure to mitochondrial DAMPs from injury sites. We are generously supported by a Department of Defense ‘Focused Program Award’ that created the Harvard-Longwood (HALO) trauma research consortium to support these translational studies. The HALO project is now beginning its fourth year, and has begun bringing its findings into the clinical domain. Dr. Hauser is a reviewer for multiple journals, an active member of many surgical societies and a Past President of the Western Trauma Association.
Wednesday, September 9, 2020
1:40 PM – 2:00 PM