Automation and High Throughput Technologies
There is a wide range of commercial equipment available for screening purposes, including reagent dispensers, plate washers, and multiparameter plate readers. Both speed and accuracy are key for use in a high throughput screening environment, where equipment can be either used in stand-alone mode, or integrated onto more complex automation platforms.
AstraZeneca have undertaken an extensive review of this equipment over the last 4 years as part of an infrastructure refresh programme. This has led us to select preferred equipment and to identify gaps in this niche area of science. In turn we have developed positive partnerships with vendors to drive the development of these key pieces of equipment, fulfilling our requirements and delivering better products.
Within this presentation we will give examples of how the following products have been developed and how they can now improve HTS workflows:
· The Certus Flex microplate dispenser: microvalve technology for contactless dispensing of a wide range of liquid classes.
· The BlueCatBio centrifugal plate washer: centrifugal emptying with the individual addition of up to four separate solutions for complex phenotypic assays.
We will outline the enhancements to date with peripheral equipment partners to collaboratively design and deliver hardware solutions and software enhancements for these devices.