Oral Abstract Session
SCMR 22nd Annual Scientific Sessions
Cardiac magnetic resonance (CMR) plays an increasing role in diagnosis and risk stratification of patients suffering from coronary artery disease (CAD). With most studies focusing on diagnostic accuracy and prognostic value, evidence from trials prospectively evaluating its role in clinical pathways and decision processes is limited.
Symptomatic CAD patients were randomized to diagnostic coronary angiography (Group 1) or adenosine stress CMR (Group 2). Revascularization was performed according to the results of the index procedure. Primary endpoint was the composite of cardiac death and non-fatal myocardial infarction. Quality of life was assessed by the Seattle Angina Questionnaire at baseline and during follw-up.
Research was funded in part by Guerbet, Roissy CDG Cedex, France.
Two hundred patients were enrolled and 194 were analyzed: 98 in Group 1 and 96 in Group 2. In Group 1, 45 (45.9%) revascularizations were performed at initial examination. In Group 2, 27 (28.1%) patients had myocardial ischemia on CMR and thus were referred to revascularization. Significant quality of life improvement after one year was observed in Group 2 in comparison to Group 1 regarding physical limitation (p
A CMR based management strategy for stable CAD patients was safe, reduced revascularization procedures and resulted in better quality of life at 12 months follow up, though non-inferiority could not be proven. Optimal timing for re-assessment remains to be investigated.