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Preclinical Development
Bioanalytics
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Rapid Fire Preclinical
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Rapid Fire Preclinical
Rapid Fire Preclinical
Rapid Fire Preclinical
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Monday, Nov 4
3:00 pm
Experimental design-driven FAIRification of data matrices: example of a principled approach
Location: Presentation Room 3, Exhibit Hall 2, 3 and 4
Philippe Rocca-Serra, PhD – University of Oxford
Monday, Nov 4
3:00 pm
Rapid Fire: Preclinical Development – Biomolecular
Location: Presentation Room 3, Exhibit Hall 2, 3 and 4
Rutwij Dave, PhD – Gilead Sciences; Anuja Paprikar, MS – St. Johns University
Monday, Nov 4
3:15 pm
Thaw-and-use Pre-labeled Target Cells for ADCC Assays
Location: Presentation Room 3, Exhibit Hall 2, 3 and 4
Shan Chung, Ph.D. – Genentech, Inc.
Monday, Nov 4
3:30 pm
Engineered Glycosylation Sites on Monoclonal Antibodies for Enhanced Stability
Location: Presentation Room 3, Exhibit Hall 2, 3 and 4
Esteban Cruz, MSc – University of Sydney
Monday, Nov 4
3:45 pm
In silico Approach to Screen mAbs, Which Saved 100 Mice
Location: Presentation Room 3, Exhibit Hall 2, 3 and 4
Rutwij Dave, PhD – Gilead Sciences
Monday, Nov 4
4:00 pm
A novel cell-based assay for predicting bispecific antibody activity
Location: Presentation Room 3, Exhibit Hall 2, 3 and 4
Lynn A. Kamen, Ph.D. – Genentech, Inc.
Monday, Nov 4
4:15 pm
Targeted Delivery of Hydroxyethyl Starch-Polyethyleneimine based Polyplexes using 8D3 antibody
Location: Presentation Room 3, Exhibit Hall 2, 3 and 4
Ekram Ahmed Chowdhury, PhD Candidate – Texas Tech University Health Sciences Center
Monday, Nov 4
4:30 pm
A Positive Charge Cluster on a Fc-fusion Impacts its Exposure
Location: Presentation Room 3, Exhibit Hall 2, 3 and 4
Ayse Meric Ovacik, PhD – Genentech
Monday, Nov 4
4:45 pm
Reversible Self-Association of a Bispecific Antibody: Effects of Temperature/Solution Conditions
Location: Presentation Room 3, Exhibit Hall 2, 3 and 4
Jai A. Pathak, PhD – MacroGenics
Monday, Nov 4
3:00 pm
Drug Repurposing in the Era of AI
Location: Presentation Room 4, Exhibit Hall 2, 3 and 4
Zhichao Liu, PhD – NCTR/FDA
Monday, Nov 4
3:00 pm
Rapid Fire: Preclinical Development – Chemical
Location: Presentation Room 4, Exhibit Hall 2, 3 and 4
Rebecca L. Kusko, PhD – Immunering Corp; Snehal Raut, MS – Texas Tech University Health Sciences Centre
Monday, Nov 4
3:15 pm
FDALabel Database: Enabling Insights from Drug Labeling to Advance Drug Safety and Personalized Medicine
Location: Presentation Room 4, Exhibit Hall 2, 3 and 4
Hong Fang, Coordinator, Senior Bioinformatician – FDA/NCTR
Monday, Nov 4
3:30 pm
Developing of a Database of Pharmacogenomics Biomarkers with Minority Groups Specific Information
Location: Presentation Room 4, Exhibit Hall 2, 3 and 4
Joshua Xu, PhD – U.S. Food and Drug Administration
Monday, Nov 4
3:45 pm
Data Integrity and QC-related Issues with Publicly Available Big Data in Pre-clinical Drug Discovery
Location: Presentation Room 4, Exhibit Hall 2, 3 and 4
Rebecca L. Kusko, PhD – Immunering Corp
Monday, Nov 4
4:00 pm
AI Based Method to Access Transcriptional Responses to Chemicals in Hepatocytes In Vivo and In Vitro
Location: Presentation Room 4, Exhibit Hall 2, 3 and 4
Benjamin Haibe-Kains – University Health Network
Monday, Nov 4
4:15 pm
LigandNet: A Machine Learning Toolkit for Predicting Protein-Ligand Activity
Location: Presentation Room 4, Exhibit Hall 2, 3 and 4
Suman Sirimulla, PhD – The University of Texas at El Paso
Monday, Nov 4
4:30 pm
Integrating AI with Predictive Stability Strategies
Location: Presentation Room 4, Exhibit Hall 2, 3 and 4
Mark Alasandro, PhD – Nalpropion Pharmaceuticals
Monday, Nov 4
4:45 pm
Obtain High Quality Information from FAERS and FOLP
Location: Presentation Room 4, Exhibit Hall 2, 3 and 4
Wenjun Bao, PhD – SAS Institute
Tuesday, Nov 5
3:00 pm
Synthetic High-density Lipoprotein Nanodiscs for Personalized Vaccination against Glioblastoma Multiforme
Location: Presentation Room 3, Exhibit Hall 2, 3 and 4
Lindsay Scheetz, MS – University of Michigan
Tuesday, Nov 5
3:00 pm
Rapid Fire: Preclinical Development – Biomolecular
Location: Presentation Room 3, Exhibit Hall 2, 3 and 4
Ashwin Parenky; Mohamad M. Kronfol, B.Pharm – Virginia Commonwealth University
Tuesday, Nov 5
3:15 pm
A Repeated Lys-ala-Leu-ala Peptide-lipid-plasmid Nanoparticle as a Cancer Vaccine Carrier
Location: Presentation Room 3, Exhibit Hall 2, 3 and 4
Sharif M. Shaheen – Daffodil International University
Tuesday, Nov 5
3:30 pm
Decorated HDL Nano-particulates Inspired Tumor Extracellular Dissociation for Site-Specific Chemo-immunotherapy
Location: Presentation Room 3, Exhibit Hall 2, 3 and 4
Yang Ding, PhD – China Pharmaceutical University
Tuesday, Nov 5
3:45 pm
Nanocarrier Carbonate Apatite Reduces off Target Effects in Cancer Treatment
Location: Presentation Room 3, Exhibit Hall 2, 3 and 4
Mohammad Borhan Uddin – Monash University
Tuesday, Nov 5
4:00 pm
Next Generation of Anthrax Vaccine; formulation development and biophysical characterization
Location: Presentation Room 3, Exhibit Hall 2, 3 and 4
Rikhav P. Gala, PhD – Fraunhofer USA, Center for Molecular Biotechnology
Tuesday, Nov 5
4:15 pm
High-Throughput in vitro Assays for Neoantigen Prediction
Location: Presentation Room 3, Exhibit Hall 2, 3 and 4
Carley Tasker, PhD – Merck Research Laboratories
Tuesday, Nov 5
4:30 pm
Folate Transport Regulation for the Treatment of Neurometabolic Disorders
Location: Presentation Room 3, Exhibit Hall 2, 3 and 4
Reina Bendayan, Pharm.D., FAAPS – University of Toronto
Tuesday, Nov 5
4:45 pm
Mechanistic Dermal Absorption PBPK Modelling Supports Bioequivalence of Complex Topicals
Location: Presentation Room 3, Exhibit Hall 2, 3 and 4
Tariq Abdulla, Ph.D. – Simcyp Limited
Tuesday, Nov 5
3:00 pm
Liposomal Doxorubicin Under Microconfinement and Microscopy
Location: Presentation Room 4, Exhibit Hall 2, 3 and 4
Kuo-Tang Liao, Kuo-Tang Liao – Food & Drug Administration - Silver Spring, MD
Tuesday, Nov 5
3:00 pm
Rapid Fire: Preclinical Development – Chemical
Location: Presentation Room 4, Exhibit Hall 2, 3 and 4
Beata Sweryda-Krawiec, PhD – Tarveda Therapeutics; Sulaiman Alhudaithi, MS – Virginia Commonwealth University
Tuesday, Nov 5
3:15 pm
Layer-by-Layer Assembled Nanoparticles for the Treatment of Colorectal Cancer
Location: Presentation Room 4, Exhibit Hall 2, 3 and 4
Justin Rosch, PhD – Oregon State University
Tuesday, Nov 5
3:30 pm
Brain Penetration and Interaction with P-gp – Novel Models
Location: Presentation Room 4, Exhibit Hall 2, 3 and 4
Li Yu, PhD – F Hoffman-La Roche Ltd
Tuesday, Nov 5
3:45 pm
FLURBIPROFEN POWDERS FOR NOSE-TO-BRAIN DELIVERY AS ALZHEIMER’S DISEASE MODIFYING AGENT
Location: Presentation Room 4, Exhibit Hall 2, 3 and 4
Gaia Colombo, PhD – University of Ferrara
Tuesday, Nov 5
4:00 pm
Tools for Mechanistic Prediction of ASD Performance: A Case Study
Location: Presentation Room 4, Exhibit Hall 2, 3 and 4
Aaron M. Stewart, M.S – Lonza - Bend
Tuesday, Nov 5
4:15 pm
Hyaluronic-Cisplatin Implant Film in Malignant Mesothelioma Recurrences
Location: Presentation Room 4, Exhibit Hall 2, 3 and 4
Paolo Colombo, Pharm D.; PhD – University of Parma
Tuesday, Nov 5
4:30 pm
Formulation Challenges Facing Naloxone Intranasal Solution
Location: Presentation Room 4, Exhibit Hall 2, 3 and 4
Manar Al-Ghabeish, PhD – US Food and Drug Administration
Tuesday, Nov 5
4:45 pm
In-vitro predictive model for transdermal skin-to-skin drug transfer
Location: Presentation Room 4, Exhibit Hall 2, 3 and 4
Nahid S. Kamal – US Food and Drug Administration
Wednesday, Nov 6
3:00 pm
Calibration of a Mechanistic Mini-model of IL-2 Induced Lymphocyte Proliferation
Location: Presentation Room 4, Exhibit Hall 4
Ronny Straube, PhD – Bristol-Myers Squibb
Wednesday, Nov 6
3:00 pm
Rapid Fire: Preclinical Development
Location: Presentation Room 4, Exhibit Hall 4
Shradda Thakkar; Sreedhar Reddy Suthe, PhD – Texas Tech University Health Sciences Center
Wednesday, Nov 6
3:15 pm
Non-intuitive Considerations for Modeling T-cell Engaging Bispecifics
Location: Presentation Room 4, Exhibit Hall 4
Fei Hua, PhD – Applied BioMath
Wednesday, Nov 6
3:30 pm
In-vivo Flux: A Breakthrough in IVIVC of Topical-dermatological-formulations
Location: Presentation Room 4, Exhibit Hall 4
Benjamin A. Kuzma – Long Island University
Wednesday, Nov 6
3:45 pm
Projections of FIH Doses for Intrathecally Administered Antisense Oligonucleotides
Location: Presentation Room 4, Exhibit Hall 4
Natalia Penner, Ph.D.
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