Bioanalytics – Biomolecular
2019 PharmSci 360
The intent of the session is to discuss the different bioanalytical approaches and associated scientific rationales, as well as challenges in support of pharmacokinetic characterization of bispecific biotherapeutics. The audience will learn about different bioanalytical approaches and associated challenges in supporting pharmacokinetics (PK) for biospecific biotherapeutics. Several case studies will be presented that will highlight the importance of critical reagents in the design of the bioanalytical assays to achieve specific and sensitive assays, as well as, considerations for the design of the bioanalytical assays based on the mechanism of action of the biotherapeutic. The audience will also have an opportunity to communicate with the experts regarding technical approaches and solutions they have used to resolve issues related to bispecific program support.