Preclinical Development – Biomolecular
2019 PharmSci 360
Previously, antibody engineering was mainly applied to improve the properties of a parent antibody by methods such as humanization, affinity maturation, stability engineering and half-life extension. Recent advances in antibody engineering have enabled us to conceive and realize novel antibody drug concepts. This presentation describes how antibody engineering technologies, such as bispecific antibody, recycling antibody and sweeping antibody, can drive the discovery of innovative antibody drugs.