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Bioanalytics
W1230-12-79 - A Faster Method for Relative Quantification of N-glycans for Therapeutic Monoclonal Antibody during Trastuzumab Biosimilar Development

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M1530-11-72 - A Fully Validated LC-MS/MS Method for Quantitation of Oxybenzone in Serum

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T1030-11-71 - A Novel Blood-Based Biomarker Distinguishes Estrogen-Negative Solid Tumors in Patient Samples

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W1030-11-72 - A Robust and Specific LC-MS/MS Method for the Measurement of Cortisol as a Biomarker in Human Serum for Clinical Studies

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M0930-11-71 - A Sensitive and Selective UPLC-MS/MS Method for Simultaneous Determination of Paclitaxel, Gemcitabine, and Carboplatin in Human Plasma and Animal Tissues

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T1230-11-73 - A Sensitive ELISA Method for the Quantification of Anti-PD-1 Antibody Drug in Human Serum

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M1530-11-73 - A Sensitive Quantification of Unbound Vemurafenib in Human Plasma Using Equilibrium Dialysis Followed By Ultra-performance Liquid Chromatography Coupled to a Tandem Mass Spectrometry

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M0930-12-78 - Activatable Core–Shell Metallofullerene Nanoprobes for High Relaxivity Magnetic Resonance/Fluorescence Bimodal Imaging of Glutathione

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M1430-11-76 - Assay Acceptance and Reporting Criteria of the Dendritic Cell Activation Assay Contributing to the Assessment of Innate Immunogenicity Risk

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T1230-12-80 - Assay and Identification of a Growth Media Containing 4 Amino Acids by a Novel HPLC Method with Charged Aerosol Detection

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W0930-12-78 - Assay Development Kit - Rapid Reagent Pair Screening and Optimization for Ligand-Binding Assays

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T1330-11-73 - Assay Performance Evaluation of Simple Plex^TM Cartridge-Based ELLA and DuoSet ELISA Assay for the Detection of B-cell Maturation Antigen (BCMA) Biomarker

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W0930-11-71 - Assessment of Chemical Reactivity of BTK Covalent Inhibitors by a Simple Reaction Assay with GSH

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T1130-11-73 - Assessment of Pre-Existing Anti-Drug Antibodies Against Novel Nanobody Therapeutic

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M1330-12-77 - Bioanalytical and Logistical Considerations in Patient Centric Volumetric Absorptive Microsampling

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W1130-11-71 - Biodistribution of TAT or QLPVM Coupled to Receptor Targeted Liposomes for Delivery of Anticancer Therapeutics to Brain In Vitro and In Vivo

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T1430-11-73 - Bullfrog oil (Rana catesbeiana Shaw) Induces Apoptosis in A2058 Human Melanoma Cells by Mitochondrial Dysfunction Triggered by Oxidative Stress

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T1130-12-80 - Cancer Stem Cells and Tyrosine Kinase Receptors Directed Non-Lipid Based Nanoparticles for Pancreatic Ductal Adenocarcinoma Imaging and Therapy

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W1230-12-77 - Capillary Microsampling Combined with a Microfluidic Immunoassay Technology Provides a Reliable and Robust Method to Measure Therapeutic Antibodies and Their Targets in Preclinical Studies

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T1130-11-74 - Case Study to Demonstrate Sensitivity in Immunogenicity Assay Should be Based on Result of Both Screening and Confirmatory Tier

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M1330-11-71 - Cell Wall Metabolite Levels in S. aureus as a Function of Growth Phase

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T1030-12-80 - Characterization of a Cysteine-conjugated ADC on a Hybrid Quadrupole-Orbitrap Mass Spectrometer

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T1230-12-81 - Confident and Efficient Characterization of Recombinant Human Follicle Stimulating Hormone with the Q Exactive HF-X BioPharma Platform

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M1030-12-79 - CTLA4 Immunoassay Validation and Application to Disease Sample Analysis

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W1130-11-72 - Detection of Dry-Eye Biomarkers in Pooled Human Tears Using Hydrogel-Coated Gold Nanoshells

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T0930-11-72 - Determination of Total and Free Melphalan Concentrations in Human Plasma Using LC-Tandem Mass Spectrometry

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T1530-11-74 - Determination of Unbound Piperaquine in Human Plasma

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T1530-12-77 - Development and Characterization of GLP-1 Total and Active V-PLEX^® Assays

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T1030-11-72 - Development and Characterization of Human and Rodent Metabolic Assays on the U-PLEX® Platform

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M1230-11-71 - Development and Characterization of LDV-Peptide Targeted Nanocarriers for Paclitaxel Delivery: A Comparative Study of Micelles, Liposomes and Solid Lipid Nanoparticles

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M1030-12-77 - Development and Implementation of a Flow Cytometry Assay to Measure Receptor Occupancy of an Anti-CD73 Antibody to Target in a Clinical Trial

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W1030-11-71 - Development and Implementation of the S-PLEX^® Platform for Converting Standard Immunoassays to High-Sensitivity Assays

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T1330-12-77 - Development and Validation of a Human Total Soluble TIM-3 Biomarker Assay for Use in Clinical Studies

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M0930-11-74 - Development and Validation of a LC-MS/MS Method for Simultaneous Measurement of Tanespimycin and Its Active Metabolite (17-AG) in Human Plasma

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T1430-12-80 - Development and Validation of a Liquid Chromatography Tandem Mass Spectrometry Method as per ICH Guidelines for Quantification of LXR Agonist GW3965 in Mouse Plasma

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W1130-12-79 - Development and Validation of a New LC-MS/MS Method for Measuring Transmucosal Delivery of Mycophenolate In Vivo

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T1530-11-71 - Development and Validation of a New LC-MS/MS Method for Measuring Transmucosal Delivery of Oxaliplatin In Vivo

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M1530-12-82 - Development and Validation of a Quantitative Method for Fulvestrant in Rat Plasma by LC-MS/MS

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M0930-11-73 - Development and Validation of a Sensitive UPLC-MS/MS Method for Simultaneous Determination of Polydatin and Resveratrol in Plasma: Application to Pharmacokinetic Study

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T1330-11-72 - Development and Validation of an LC-MS/MS Method for the Simultaneous Quantitation of Fifteen Bile Acids in Human Serum

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W1130-12-77 - Development and Validation of LC-MS/MS Methods for the Quantitation of Commonly Co-administered Drugs and in Support of Several Clinical Studies

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M1430-11-74 - Development of a Neutralizing Antibody Assay with Improved Drug Tolerance for an Investigational Antibody by Applying Drug Depletion to Serum Samples

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M1430-11-73 - Development of a Novel Cell-Based Assay for the Detection of Neutralizing Antibodies to PF-06730512

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W1030-12-78 - Development of a Novel U-PLEX Method to Differentiate Between Anti-drug Antibody and Target Signals

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M1530-12-78 - Development of a Sensitive LC-MS/MS-Based Method for the Simultaneous Use of Mannitol and Sucrose as Markers of Blood-Brain Barrier Integrity

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M1530-12-81 - Development of a Simple and Robust Tryptic Digestion Method for the Determination of Therapeutic Antibodies by LC/MS

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T1430-12-78 - Development of an Intestinal Tissue Bioanalytical Assay Method for Quantitation of an Antiviral Drug Active Metabolite (CMX521-PPP) and its use in a Pre-Clinical in vivo Analyte Localization Analysis

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W1130-12-78 - Development of Highly Sensitive (4 pg/mL LOQ) HPLC-MS/MS Bioanalytical Method to Support Clinical Studies of an Inhaled Compound

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M1330-11-73 - Distribution and Recovery of Human Neonatal Fc Receptor (FcRn) in Sucrose Gradient Fractions from Human Liver Tissues using Multiple Reaction Monitoring (MRM)-based Targeted Proteomic Methods

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M1330-12-79 - Driving Effectiveness of the Analytical Method Lifecycle with Ruggedness Studies

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W1230-11-72 - Drug Delivery Using Biocompatible Polymer Encapsulated Magnetic Nanocarriers (PE-MNCs) Enhances Neurite Outgrowth on Inhibitory Substrate

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T1130-12-79 - Dual Functionalized Liposomes for Efficient Co-delivery of Anti-cancer Chemotherapeutics for the Treatment of Glioblastoma

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W1130-12-80 - Effect of Rumex acetosa Extract on P-gp and OATP1A2

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M1030-11-74 - Effect of Freeze Thaw Cycles of Conjugated Reagents on Immunogenicity Assays

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M1330-11-76 - Effect of Vancomycin on Cytoplasmic Peptidoglycan Intermediate Levels in Vancomycin Resistant Enterococci

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T1130-12-78 - Effective Formulation of Antioxidant Natural Compound to Polymeric Nanosuspension Shows Better Tumor Regression and Survival

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T1330-12-79 - Enantiomeric Purity Analysis for Solid Phase Synthesized Peptide Active Pharmaceutical Ingredients

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T1230-11-72 - Evaluation of an Acid-Treatment Procedure on the Interference of Anti-Drug Antibodies in a Pharmacokinetic Assay

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T1330-11-74 - Extracellular Vesicles Derived from Brain Endothelial Cells for DNA Delivery

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W0930-12-77 - Fit-for-Purpose Immunoassay Development for PEG Using DoE and Multiple Platforms

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M1130-12-79 - Fit-for-Purpose Method Validation of Clinical Biomarker Assays to Show Proof of Biology with Automated Western Blot Technologies

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M1030-11-73 - Gene Therapy: Strategies to Generate Critical Reagents to Support Assay Development

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T1430-12-77 - Generation of High-Resolution Metabolite Profiles by HPLC+AMS

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T0930-12-77 - Generic Method for Quantitation of Human Fc-Fusion Proteins in Mouse Plasma Using BLI Technology

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T1530-11-73 - High-Performance Liquid Chromatography Method Development and Validation for the Determination of Celastrol in Rat Plasma

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M1430-11-71 - High-Throughput In Vitro Assays for Immunogenicity Predictions and Risk Assessment

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M1330-11-75 - Identification of Asparagine Enantiomers and Their Hydrates by Terahertz Time-Domain Spectroscopy

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T1230-12-77 - Identifications of MabSelect SuRe LX Sepharose Resin and 15 Other Resin Analytes

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M1130-11-74 - Immune Checkpoint Inhibitor Antibody Drug Conjugate for Chemotherapy Guided Immunotherapy of Solid Tumors

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M1130-11-71 - Improving the Encapsulation of Gedatolisib, a Weakly Hydrophobic Drug with Limited Aqueous and Non-aqueous Solubility, in Polymeric Nanoparticles via Flash Nanoprecipitation

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M1030-11-71 - In Vitro Assessment of Immunogenicity for an Exploratory Gonorrhea Vaccine

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T1430-11-71 - Influence of Penetration Enhancers on Drug Deposition in Different Skin Layers Using Exercised Human Cadaver Skin

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T1330-12-78 - Laser Microdissection-LC-MS/MS Method for Quantitative Tissue Distribution Analysis (QTDA) of Tumor Tissue

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T0930-12-78 - LC-MS Method Development for Quantitation of Midazolam, Ketamine and Their Metabolites: Application to a Pharmacokinetic Study in Patients on Extracorporeal Membrane Oxygenation Therapy

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T1030-11-73 - LC-MS/MS Method for Quantification of Orexin-A in Plasma, a Biomarker for Narcolepsy

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T0930-11-71 - LC-MS/MS Quantification of Polypeptide ACTH in Human Plasma for Pharmacokinetic (PK) and Toxicokinetic (TK) Studies

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M1230-11-74 - Lipid Nanoformulations of Vancomycin and Cefazolin in Methicillin-Resistant Staphylococcus aureus Superbug Infection: A Perspective on Efficacy and Uptake

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W1130-11-73 - Lipid Nanoparticle for Active Targeted Delivery of Vancomycin in MRSA Infection

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T1530-11-72 - Lower Exposure of Simvastatin and Its Active Metabolite in NAFLD Rat Caused by Lower Intestinal Absorption and Higher Biliary Excretion

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W0930-12-79 - Magnetic Biosensors for Characterizing Protein-Protein Interactions in Complex Biological Matrix

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M0930-12-77 - Modernization of Insulin Bioidentity Testing with In-Cell Western Technology

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T1230-12-78 - MSD and Ella Multiplex Assay Development of IFN-γ, CCL8 and CXCL10

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T1230-11-71 - MSD GOLD™ Streptavidin and Small Spot Streptavidin Plates: Multi-year Reproducibility and Application to Pharmacokinetic Assay Development

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M1430-12-79 - Neurofilament Light (NfL) is a Bona-fide Blood Based Biomarker for Neurodegenerative Diseases

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W1230-12-78 - New Bio-compatible Physiological Bicarbonate Buffer System for Dissolution Testing

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W1230-11-73 - Novel Elvitegravir Nanoformulation for Drug Delivery Across the Blood-Brain Barrier to Achieve HIV-1 Suppression in the CNS

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T1330-11-71 - Optimization of a Commercial ELISA to Measure Serum -Defensin 2 in Patients with Psoriasis

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M1130-11-72 - Optimization of Solid Lipid Nanoparticles to Deliver Efavirenz to Brain for Treatment of Neuro-AIDS

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T1430-12-79 - Overcoming Stability Issues in the Development of an LC-MS/MS Method for the Quantitation of Azacitidine in Human Plasma

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W1030-12-80 - PandA Optimization Strategy: Keys to Producing Meaningful Immunogenicity Data and Avoiding the Pitfalls of this Highly Drug Tolerant Format

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M1130-11-73 - PD-1 siRNA-Solid Lipid Nanoparticles Inhibit Tumor Growth

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T1230-11-74 - PEGylation Affects the Pharmacokinetic Assessment of Pegfilgrastim Using Ligand Binding Assays

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M1430-12-78 - Pharmacokinetic and Pharmacodynamic Herb-Drug Interactions between Simvastatin and Gardenia Jasminoids in Healthy and NAFLD Rats

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M1530-11-71 - Pharmacokinetics of Novel Organic Carbon Monoxide Prodrugs BW-CO-115 and BW-CO-203 via Oral Administration

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T1230-12-82 - Photoacoustic Nano-Diagnostics of Solid Tumors

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T0930-11-73 - PK Assay Variability Linked to Plate Positional Effects on MSD Plate Reader

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M1130-12-78 - Platform Comparisons for Measurement of CCL18: ELISA, IMPACT, and ELLA

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T1130-11-72 - Pre-existing Antibodies to Biotherapeutics: Two Case Studies for Immunogenicity Assay Design and Appropriate Cut Point Determinations

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M1030-12-78 - Profiling the Promoter Activity of Different L1 Families in the Mouse Genome to Build an Endogenous Animal Model for Drug Screening

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W1030-12-79 - Qualification of a Drug-Tolerant Anti-Drug Antibody Assay for C1 Inhibitor in Human Serum

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M1130-11-75 - Quantification of Chimeric Antigen Receptor T Cells in Blood with a Novel Quantitative PCR Methodology-Recommendation of the Use of the Volume-Based Unit (copies/μL) for the Cellular Kinetic Studies

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T1530-12-78 - Quantification of Dehydroepiandrosterone (DHEA), 17α-hydroxyprogesterone (17-OHP) and 17α-hydroxypregnenolone (17-OHPreg) in Human Serum Using AB Sciex Triple Quad 5500 LC MS/MS System

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T1030-12-77 - Quantitation of Biotherapeutics via LCMS - Surrogate Peptide versus Intact Mass Analysis

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T1030-12-82 - Quantitation of IgG in Human Serum with LC-MS/MS Bottom-Up Strategy

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M1130-12-77 - Quantitation of Myostatin/GDF8 in Human Serum Using an Enzyme Linked Immunosorbent Assay (ELISA)

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M1530-12-77 - Quantitation of siRNA and Its Metabolites in RNA-Induced Silencing Complex in Rat Liver Using Immunoprecipitation LC-MS/MS (IP-LC-MS/MS)

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T1130-11-71 - Rapid In-House Determination of Cut Point Values for Immunogenicity Assays Using JMP and Excel

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W1030-12-81 - Re-validation of an Immunogenicity Method Following the Issuance of the Finalized FDA Guidance and Assessing the Impact on Clinical Data Interpretations

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T1230-12-79 - Robust Chemometric Analyses of 2D-NMR Methyl Fingerprints for mAb Therapeutics

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M1430-11-72 - Screening for Pre-existing Neutralizing Antibodies against AAV Serotypes 1, 2, 5, 6, 8 and 9 In Sera of Different Strains of Pigs

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W1030-11-74 - Serological Prevalence of Toxoplasmosis in Pregnant Women in Luanda (Angola): Diagnosis of Toxoplasma gondii on Placental Fragments by Nested-PCR

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M0930-11-72 - Simultaneous Detection and Quantification of Lapatinib and Capecitabine in Plasma and Tissue Using a Sensitive Liquid Chromatography-Tandem Mass Spectrometry Method

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M1530-12-80 - Simultaneous Determination of Coproporphyrin-I and Coproporphyrin-III in Human Plasms and Human Urine Using LC-MS/MS

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M1530-11-74 - Simultaneous Quantitative Analysis of Anti-infectious Disease Drug Classes in Human Plasma by LC-MS/MS

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T1130-12-77 - Spectral Investigation into Qualitative Evaluation of Interaction between Doxorubicin Hydrochloride Entrapped within Poly(butyl)cyanoacrylate Nanoparticles

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W0930-11-72 - Stability Testing of Compounded Enoxaparin Sodium Injection in Pre-filled Syringesby Using HPLC Isocratic Method

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W1030-12-82 - Standardized and Efficient Modular Automation of a DOE Driven Method Development of a Solution Phase Bridging ELISA Assay to Support Immunogenicity Assessment

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W1030-12-77 - Strategies for Overcoming Drug Target Interference in Anti-Pembrolizumab Antibody Detection

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M0930-12-79 - Streamlined Impurity Analysis Using High Throughput Analytical Automation to Support Process Development and Characterisation Studies

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W1030-11-73 - Systematic Assay Screening for Specific Biomarker Analysis: Circumvent Antibody Bias

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T1430-11-72 - The Application of Light-Absorbing Photostabilizers for the Determination of Protoporphyrin IX in Human Plasma by LC-MS/MS

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M1230-11-73 - The Induction of Effective Cancer Immune Response by the Combination of Lipid Based Bubbles and Therapeutic Ultrasound

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T1030-12-78 - The Relationship between Selectivity and Drug Delivery Efficiency of Peptide-Drug Conjugate: A Comparison of Three EGFR-Targeting Peptide-Drug Conjugates with Different Affinities

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M1430-12-77 - Tracing Drug Induced Liver Injury (DILI) signatures by Harnessing Cancer Cell Lines

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T0930-12-79 - Turning a Negative to a Positive with Anti-metatype Affimer Reagents

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M1530-12-79 - Ultrasensitive Bioassay for Detection of a TNFα-Specific Antibody in Mouse Samples from Rectal vs IV Administration

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T1530-12-79 - Ultra-sensitive Immunoassay Characterization using Endogenous Validation Samples.Ultra-sensitive Immunoassay Characterization using Endogenous Validation Samples

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M1030-11-72 - Using Monosaccharide Peptide/Protein Conjugates as Surrogates to Better Understand Protein-Polysaccharide Conjugate Vaccine Structures

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M1430-11-75 - Validation of a cell lysate based assay to detect antibodies against CFTR

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T1030-12-81 - Validation of Multiple LC-MS/MS Methods for Quantification of Bevacizumab and Ranibizumab in Human Plasma after Intravitreal Administration

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M1230-12-77 - Validation of Quantitative Ligand Binding Assay Using Mouse Serial Sampling

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Clinical Pharmacology
W1130-13-87 - A Clinical Study Design to Evaluate Whether the Systemic Bioavailability of Topical Drugs may Influence the Assessment of Local Dermal Pharmacokinetics by Dermal Open Flow Microperfusion (dOFM)

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T1430-13-83 - A Drug-Drug Interaction Study to Study the Effects of Multiple Doses of the CYP3A4 Modulators Itraconazole and Rifampin on the Single Dose Pharmacokinetics of Vatiquinone

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T0930-13-88 - A Drug-Drug Interaction Study: The Effect of Multiple Doses of Vatiquinone on the Single Dose Pharmacokinetics of Tolbutamide and Omeprazole

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W1030-13-83 - A Modeling Approach to Predict the Outcome of a Bioequivalence Study: Application to a Triple Combination Tablet of Amlodipine/Irbesartan/Hydrochlorothiazide

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T1330-13-85 - A Multiscale Mathematical Model to Study Nanomedicine Delivery in Solid Tumors

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M1530-13-85 - A Pharmacokinetic Study of Two Oxybutynin Transdermal Formulations with Transient Heat Exposure

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M1130-13-89 - A Population PK-PD Model to Characterize the Increase in Gastrointestinal Motility by YH12852, a Highly Selective 5-HT4 Receptor Agonist, in Healthy Subjects and Patients with Functional Constipation

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M1030-13-85 - A Retrospective Investigation of Bioanalytical Issues in Pharmacodynamic (PD) Studies Submitted in Abbreviated New Drug Applications (ANDAs) for Low Molecular Weight Heparin (LMWH) Drug Products

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T1330-13-88 - A Target-Mediated Drug Disposition Population Pharmacokinetic Model of GC1118, a Novel Anti-epidermal Growth Factor Receptor Antibody, in Patients with Refractory Solid Tumors

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T1130-13-86 - Anti-inflammatory Effect oF Selective CB2 Inverse Agonists in Murine and Human Microglial Cells

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T1130-13-83 - Application of Delay Differential Equations in Modeling Absorption Problems Related to Irbesartan Pharmacokinetics

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M1030-13-84 - Application of Physiologically-Based Pharmacokinetic Absorption Modeling and Simulations: Risk Assessment and Control of Critical Quality Attributes for Medical Countermeasure Drug Products

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T1030-13-87 - Applications and Benefits of Healthy Volunteer Trials to Accelerate Oncology Drug Development

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T1130-13-87 - Assessing OATP1B1- and OATP1B3-Mediated Drug-Drug Interaction Potential of Vemurafenib In Vitro in the Presence of Protein Binding and Using Static and Physiologically-Based Pharmacokinetic Models

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M1330-13-84 - Assessment of Target Inhibition Using a Pharmacokinetic/Pharmacodynamic Model following Intravitreal Administration of an Anti-HtrA1 Antigen-Binding Fragment in a Phase I Study

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W0930-13-84 - Assessment of the Impact of Drug Dissolution on Pharmacokinetics of Diltiazem Extended Release Drug Products Using Physiologically Based Pharmacokinetic Analysis

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W0930-13-88 - Biopharmaceutic In Vitro In Vivo Extrapolation (IVIV_E) Informed PBPK Model of Ritonavir Norvir^® Tablet Absorption in Humans Under Fasted and Fed State Conditions

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M1430-13-86 - Biopharmaceutical Profile, Bioavailability, Food Effect, and Pharmacokinetics of Vericiguat: A Novel Soluble Guanylate Cyclase Stimulator

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M1530-13-86 - Brain Metabolism of cis- and trans-Permethrin

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T0930-13-86 - Buffer Capacity of Topical Products: In Vitro and In Vivo Proof and Clinical Significance

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T0930-13-83 - Circulating Endothelial Cells (CECs) as a Diagnostic and Prognostic Marker for Pulmonary Arterial Hypertension (PAH): A Proof of Concept Study in PAH Patients

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M1130-13-87 - Comparing the Performance of First-Order Conditional Estimation (FOCE) and Different Expectation-Maximization (EM) Methods in Handling Complex Nonlinear Parent-Metabolite Pharmacokinetic Model

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W1230-13-84 - Comparison of Three Topical Drug Permeation Enhancers in Human Cadaver Skin Using Conventional Franz Cell Permeation and Mass Spectrometry Imaging

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T1530-13-87 - Compartmental Pharmacokinetic Model Analysis of Vincristine and Its M1 Metabolite in Kenyan Pediatric Cancer Patients

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T1530-13-89 - Consistent Lung Delivery of Inhaled Triple ICS/LAMA/LABA Fixed-Dose Combination Using Co-suspension Delivery Technology: An In Silico Modeling Study

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W1130-13-84 - Dermatopharmacokinetic Assessment of Bio(in)equivalence of Topical Metronidazole Creams Using Tape Stripping

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T1230-13-87 - Design, Synthesis and Biological Screening of Novel Quinazoline and Pyrrolotriazine Derivatives as Potent HER-2 and VEGFR2 Inhibitors

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M1030-13-88 - Developing a Physiologically Based Pharmacokinetic Module of Sofosbuvir to Predict a Pediatric Population Dose Using Simcyp Simulator

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T1330-13-84 - Development and Verification of a Physiologically Based Pharmacokinetic – Pharmacodynamic (PBPK-PD) Canine Model for Propofol in Greyhounds and Beagles

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T1330-13-87 - Development of a PBPK Model for the Prediction of Amiodarone Pharmacokinetics in Fed and Fasted State Using the Advanced Dissolution, Absorption and Metabolism (ADAM) Model

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M1030-13-89 - Development of a Physiologically Based Pharmacokinetic (PBPK) Model for Intra-articular Delivery

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W0930-13-87 - Development of Pharmacokinetic Evaluation System for Effective Formulation Design (X): The Study of the Gastrointestinal Behavior under Dosing OD Tablets without Water by Using GastroPlus^TM

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M1530-13-87 - Development of Pharmacokinetic Evaluation System for Effective Formulation Design for Generic Medicines: Prediction of Drug Absorption from OD Tablets Containing Poorly Water-Soluble Drugs in Human

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M0930-13-84 - Differential Genome-Wide H3K9 Acetylation Changes Induced by DNA Hypomethylating Agents

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T1230-13-86 - Differential Packaging of Cytokines/Chemokines in Macrophages-Derived Exosomes upon Exposures to Tobacco and HIV: Potential Role of These Exosomes in Smoking-Induced HIV Pathogenesis

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M1430-13-87 - Efavirenz Physiologically Based Pharmacokinetic Model Development and Validation as a Moderate CYP3A4 Inducer for Drug-Drug Interaction Predictions

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M1530-13-83 - Effect of Food on the Pharmacokinetics of Monomethyl Fumarate After Administration of Diroximel Fumarate

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M1230-13-84 - Efficacy of Millets as Adjuvant to Chemotherapy in Reducing Adverse Effects in a 56 Year Old Female Patient Reported with Stage 4 Advanced Ovarian Cancer

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T1530-13-86 - Establishment of a Hollow Fiber Infection Model for Preclinical PK/PD Evaluation of Novel Spectinamide Antituberculosis Agents

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M0930-13-88 - Estimation of Brain Entry Rate of Oxycodegol, a Selective, Long-Acting Full µ-opioid Receptor Agonist, in Humans Using PBPK-PD Modeling

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M1230-13-86 - Evaluating Food Effects on Oral Drug Absorption in Infants: An Exploratory Study in Healthy Adults

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T0930-13-85 - Evaluation of Different Inhibitory Effect of Itraconazole and Clarithromycin on Hepatic CYP3A Activity Using Oral Sildenafil and Endogenous Metabolic Markers for Hepatic CYP3A Activity

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T1430-13-85 - Evaluation of Dried Blood Spot Sampling Method toward Therapeutic Monitoring of Radotinib in the Treatment of Chronic Myeloid Leukemia

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M1430-13-88 - Evaluation of Methamphetamine and Amphetamine Disposition Discrepancy upon Selegiline Transdermal Patch Administration in Healthy Volunteers Versus Special Populations Using PBPK Modelling

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T1030-13-85 - Evaluation of U.S. FDA Approved Generic Oral Solution Products

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W0930-13-89 - Exploring Clinical Relevance of Dissolution Testing by Physiologically Based Biopharmaceutics Modeling (PBBM)

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M1130-13-85 - Exposure Predictions of Prodrug CZ48 and Active Campothecin, CPT, in Humans: Population PK Modeling and Simulation of CZ48 and CPT

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T1030-13-89 - FDA Perspective on Current Challenges in Bioequivalence Evaluation for Topical Dermatologic Corticosteroid Abbreviated New Drug Applications (ANDAs)

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T1030-13-88 - FDALabel: Database on the Amazon Cloud for Drug Labeling Information

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M1030-13-87 - Gender Differences in Pharmacokinetics, Excretion Pattern, and Tissue Distribution Following Administration of 4-n-nonylphenol in Rats

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T0930-13-84 - Impact of Operator Variability on the Reproducibility of Tape Stripping Results

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T1230-13-85 - In Vitro and In Vivo Interpretations of Effect of Isoflurane Anesthesia on Membrane Lipids of Blood-Brain Barrier: Potential Clinical Implications

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M0930-13-86 - In Vitro Study of Novel Bone-Targeting Angiotensin 1-7 Conjugate Effects on Cell Survival and mRNA Expression of Different Components of Renin-Angiotensin System in Various Cancer Cell Lines

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W1030-13-87 - Inflammation Responsive Drug Delivery for Localized Opioid Release to Combat Chronic Pain in Osteoarthritis

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T1230-13-83 - Influence of Rifampin-Mediated OATP1B1/1B3 Inhibition on the Pharmacokinetics of Clazosentan

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T1330-13-86 - Investigating the Impact of Crohn's Disease on Oral Budesonide Pharmacokinetics Using In Vitro Dissolution Testing and PBPK Modeling

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T1430-13-84 - Investigations of Catheter Obstructions from Materials Collected in Patients with Type 1 Diabetes Treated by Intraperitoneal Insulin Infusion

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T1430-13-87 - IPE between PharmD and Exercise Science Students

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M0930-13-85 - Lipidomic Alterations in Docetaxel-Resistant Prostate Cancer

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T1530-13-84 - Longitudinal Impacts of Roux-en-Y Gastric Bypass Surgery on the Atorvastatin and Simvastatin Metabolisms and 3D PK/PD Correlations

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T1530-13-83 - Mass Balance, Metabolic Disposition, and Pharmacokinetics of [¹⁴C]Etrasimod Following Oral Administration to Healthy Male Volunteers

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M1330-13-86 - Mean Residence Time Values for Monoclonal Antibody Drugs

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T1530-13-85 - Mechanism-Based Population Pharmacokinetic/Pharmacodynamic (PKPD) Modeling of ISIS 702843, a TMPRSS6 Targeting Antisense Oligonucleotide (ASO) to Guide Early Clinical Development

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T1130-13-84 - MEK1/2-Mediated Chemosensitization in Glioblastoma Cells

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M1430-13-85 - Microdosing Strategy for Absolute Bioavailability Studies: A Case Study on ¹³C-Venetoclax, from Development to the Clinic

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W0930-13-83 - Multi-scale PK Modeling of Biotherapeutic Formulations Injected in Human Subcutaneous (SC) Tissue

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M0930-07-43 - Cell Assembly-Mediated Delivery of Checkpoint Inhibitors for Leukemia Immunotherapy

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T1030-07-44 - Design of Surface Modified Liposomal Nanoparticles for Targeted Delivery of Gene to the Brain

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W1230-05-30 - Design of Ternary Amorphous Solid Dispersions Containing a High Viscosity Polymer and Mesoporous Silica by Hot Melt Extrusion to Produce a Heightened Parachute Effect During Dissolution

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W1130-07-44 - Design of Tubular Electrospun Grafts Containing Vancomycin for Vascular Tissue Regeneration

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M1230-01-07 - Design, Development, and In Vitro Characterization of a New 8-aminoquinoline Derivative Loaded Solid Lipid Nanoparticles for Relapsing Malaria

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M1030-07-46 - Design, Formulation, and In Vivo Evaluation of 3D Printed Dexamethasone Polypropeylene Fumarate (PPF) Biodegradable Stents for Vascular Applications

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M1030-02-11 - Design, Synthesis and Characterization of Biotinylated Polymeric Micelles to Combat Breast Cancer

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M1330-02-08 - Designing a Novel High Hydroxyl Oil-Based Polyol as a Drug Delivery Carrier

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T1230-06-41 - Detection of Host Cell Proteins (HCPs) in Biotherapeutics with Reproducible UHPLC and HRAM Orbitrap-Based MS

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M1130-06-41 - Detection of Silicon as a Process Impurity in Captisol® (Betadex Sulfobutyl Ether Sodium) by ICP-MS

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W0930-02-08 - Determination and Identification of Biomarkers for Normal and Diabetic Rats under Aerobic and Anaerobic Exercise

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M1230-07-46 - Determination of Betadex (β-Cyclodextrin) According to the USP Betadex Sulfobutyl Ether Sodium Monograph and Possible Improvements

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T1230-06-37 - Determination of Residual Hydroxylamine in Complex Formulations

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M1330-06-40 - Developing a Fast, Non-Destructive Terahertz Dissolution Assay of Tablets During Manufacture

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W1230-02-14 - Developing an Affinity-Based Subcutaneous Formulation for a GLP-1-Like Agonist

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T0930-07-44 - Developing an Oral Dissolving Film (ODF) Formulation of Microparticulate Gonorrhea Vaccine

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T1230-06-38 - Development and Application of Riboflavin and Diphenhydramine Impurity Solutions for Pharmacopeial Testing

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T1030-06-40 - Development and Application of USP Apparatus 4 for In Vitro Drug Release from Omega-3-Acid Ethyl Esters Capsules

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T1530-04-26 - Development and Characterisation of Ketoprofen-Benzocaine Deep Eutectic Mixtures

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M1530-04-26 - Development and Characterisation of Procaine-Ketoprofen Deep Eutectic Mixtures

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T1230-07-44 - Development and Characterization of 3D Printed Delayed-Release Orodispersible Film Loaded with Lansoprazole Drug

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M1230-01-05 - Development and Characterization of an In Situ Thermosensitive Electro-Responsive Nanogel-Composite for Controlled Release of a Bioactive Agent for Nose-to-Brain Delivery

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M1430-03-18 - Development and Characterization of Nanoparticulate Delivery System for the Treatment of Cutaneous Melanoma

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T1530-02-13 - Development and Characterization of Nanoparticulate Dosage Form to Deliver Anti-cancer Drug Carmustine Across the Blood-Brain Barrier

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M1530-01-04 - Development and Characterization of Orally Disintegrating Films Loaded with High Levels of Ibuprofen Nanoparticles

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T1330-02-12 - Development and Characterization of PLGA Nanoparticles for the Delivery of mitoNEET Ligand NL-1 in Stroke Treatment

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M1530-03-15 - Development and Characterization of Polymeric Films Containing Thymoquinone for the Treatment of Wound Healing and Bacterial Skin Infections

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W1030-07-49 - Development and Characterization of Sublingual Insulin Film

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T1230-03-20 - Development and Evaluation of a Micro-dispersed Drug-in-Adhesive Delivery System of 3-fluoroamphetamine

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T1230-03-21 - Development and Evaluation of Dermatological Formulation with Enhanced In Vitro Drug Release Using Reduced Level of Diclofenac Sodium

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T1230-01-06 - Development and Evaluation of Sorafenib-Loaded Nanoparticles as Inhalable Drug Delivery Carriers for Treatment of Non-Small Cell Lung Cancer

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T0930-05-34 - Development and Optimization of Fast Dissolving Buccal Films Loaded with Ketoprofen Nanoparticles Using Box-Behnken Design

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W1230-03-18 - Development and Optimization of Oil in PEG Cream

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W0930-07-46 - Development and Stability of an Extraction Resistant Drug Formulation Containing Crosslinked Poly(Acrylic Acid)

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W1130-06-40 - Development and Validation of a High-Performance Liquid Chromatography (HPLC) Method for the Determination of Formaldehyde and Acetaldehyde Content in Microcrystalline Cellulose Samples

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W0930-03-20 - Development and Validation of a Novel HPLC-UV Analytical Method and Stability Evaluation of 4-phenylbutyric Acid, an Antidote for Warfare Chemicals

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M1030-07-48 - Development and Validation of a Sensitive Method for Alkyl Sulfonate Genotoxic Impurities Determination using Gas Chromatography Coupled to Triple Quadrupole Mass Spectrometry

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T1530-06-38 - Development and Validation of Fast Stability indicating UPLC Method for Quantification of Pseudoephedrine, Dextromethorphan, Triprolidine,Guaifenesin and preservatives present in cough and cold syrups

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M1230-06-41 - Development and Validation of In Vitro Release Test (IVRT) Method for Ophthalmic Suspensions – A Walkthrough Exercising Regulatory Guidance

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T1330-06-38 - Development of a Comprehensive GC-MS Headspace Method for the Evaluation of Multiple Antimicrobial Preservatives in Peptide and Protein Formulations

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M1230-02-08 - Development of a Folate-Decorated, Macrophage-Targeting Nanoemulsion System for HIV Treatment

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M1130-01-03 - Development of a Functional Polymer with an Environmental pH Responsiveness for Cancer Targeting

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W1230-03-20 - Development of a Library of Plastics Additives for Identification of Extractables

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M1330-02-14 - Development of a Lipopolysaccharide Antagonist for the Systemic Treatment of Sepsis

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T1430-02-12 - Development of a Mechanistic Absorption Model to Bridge Late Stage Formulation for a BCS Class II Drug Candidate

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T1230-07-49 - Development of a Medicated Chewing Gum Containing Sceletium tortuosum and Process Optimization Utilizing the SeDeM Diagram

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W1130-07-47 - Development of a Method to Measure the Encapsulation Efficiency of Phenylalanine in Ethylcellulose Microcapsules and Its Use to Determine Efflux of Phenylalanine from the Microcapsules

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M0930-03-20 - Development of a Novel and Innovative Drug Delivery System for Local Targeting of the Esophagus

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T1030-07-47 - Development of a Novel In Vitro Model to Predict Risk of Skin-to-Skin Drug Transfer during Transdermal Hormonal Replacement Therapy

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M1530-07-44 - Development of a Packaging System for a Cell Therapy Product Suitable for Cryogenic Storage by Utilizing Residual Seal Force and Headspace Oxygen Content Analysis

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W0930-01-05 - Development of a Protein-Free Amphiphilic Lycopodium Spore Microcapsule for Oral Therapeutics Delivery

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W1230-04-28 - Development of a Solid Self-Emulsifying Drug Delivery System Containing Dutasteride

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W1030-04-26 - Development of a Solubilised Capsule Formulation Using Co-micronisation and Precipitation Inhibition

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T1130-05-34 - Development of a Sustained Release Orally Disintegrating Films for Tamsulosin Hydrochloride

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M1230-05-32 - Development of Abuse Deterrent Formulation for Loperamide Using Hot Melt Extrusion

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W1030-06-40 - Development of an GMP Automated Platform for API Forced Degradation Studies and Method Linearity

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W1230-06-38 - Development of an HPLC Method for the Identification of a Disaccharide Counter-ion in the DP Investigation on the Anomalous Behavior of the Disaccharide Standard Solution

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W1130-05-29 - Development of an In Situ Gel Formulation for the Enhanced Topical Delivery of Niacinamide on Microporated Skin

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M0930-01-05 - Development of an Inhaled Clofazimine Formulation for the Treatment of Pulmonary Tuberculosis

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M1230-03-18 - Development of an Ointment-Based Topical Ocular Delivery System for Hydrogen Sulfide

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M1130-02-13 - Development of Anti-inflammatory Drug-Eluting Polymeric Devices

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T1430-02-14 - Development of Aprepitant-loaded Phosphatidylcholine Solid Dispersions for Enhancing Dissolution Rates

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W1130-03-20 - Development of Carboplatin Loaded Liposomes for Pulmonary Delivery

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T1130-05-31 - Development of Different Density-Controlled Release 3D Printing Tablets Using HME Technologies

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T1030-01-05 - Development of Eudragit Based Natamycin Films for Ophthalmic Applications Using Design of Experiments Approach

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M1330-01-06 - Development of Excipient-Free Caveolin-1 Scaffolding Peptide Dry Powder Inhalation for Treatment of Idiopathic Pulmonary Fibrosis – Stability Study

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T1030-01-04 - Development of High Potency Tacrolimus Dry Powder for Inhalation by Thin Film Freezing

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T0930-03-16 - Development of Hyaluronidase Sensitive Palm Oil Based Organogel for In Vitro Release of HIV/AIDS Microbicides Using Artificial Neural Networks

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T1530-07-48 - Development of Implantable Malaria Chemoprophylaxis

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T1130-02-13 - Development of In Vitro - In Vivo Correlations (IVIVC) Using the Gastro-Intestinal Simulator (GIS)

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W0930-01-04 - Development of Inhalable Solid Lipid Nanoparticles Formulation by Hot Melt Extrusion Technique

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T1530-03-19 - Development of iRGD Conjugated Semifluorinated Nanoassemblies for Targeted Drug Delivery to Solid Tumors and Study of the Polymer Architecture Effect to the Delivery Platform

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M1130-04-22 - Development of Monoacetyldiglyceride (MADG) Loaded Self-emulsifying Granules with Enhanced Oral Bioavailability Using Fluid Bed Granulator

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M1430-04-27 - Development of Nano-amorphous Spray Dried Powder to Improve Dissolution Rate: Stabilizer Selection and Formulation Optimization Using Quality by Design (QbD) Approach

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W1030-03-15 - Development of Nanoparticles for the Treatment of Lymphatically Metastasizing Melanoma

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T1530-07-46 - Development of Novel Bilayer Microarray Patches (MAP) Containing a High Dose of Long-Acting Cabotegravir Nanosuspension as an Alternative to Injectable Delivery

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T1230-07-43 - Development of Novel Formulations Through 505(b)(2) Pathway Prevailing Over the Regulatory Barriers

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M0930-02-14 - Development of Oral Solid Dosage Form for Sunitinib Free Base with Improved pH-Dependent Dissolution Rate and Absorption

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T1530-03-21 - Development of Polyssacharide-Based Nanoparticles for Mucosal Vaccine Delivery Against Group A Streptococcus

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W1030-04-25 - Development of Rutin smartCrystals^®for Targeted Dermal Application

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T1230-06-39 - Development of Solution Based Certified Reference Materials for the Analysis of Gabapentin Pharmaceutical Impurities

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T1130-07-48 - Development of Stability Indicating RP-HPLC Method for an Anthraquinone Botanical Extract in a Topical Formulation for Treatment of Wounds

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M1330-07-49 - Development of Supersaturable Solidified Self-nanoemulsifying Drug Delivery System to Enhance the Dissolution Rate of a Ketoprofen

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W0930-02-09 - Development of the Customized Cardiovascular Stent Made from the Biomimetic Hydrogel

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M1030-07-44 - Development of Transdermal Controlled Release Formulation for Tacrolimus

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M0930-03-19 - Development of Pediatric Anti-HIV Formulations with Improved Dissolution Characteristics

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M1430-05-29 - Dexlansoprazole Dual Delayed Release Formulation Using pH Dependent ECOPOL® Polymers

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M1030-04-22 - Diclofenac Sodium Entrapment Efficiency and Stability in MCM-41 Carrier Which Surface Had Been Amino-Functionalized Using Two Methods

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M1130-07-45 - Difference in Palatability Among the Formulations of Kremezin®, an Oral Absorbent of Uremic Toxins, in Chronic Kidney Disease (CKD) Patients

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W1230-02-08 - Different Liposome Classes Interact Differently with Brain Endothelial Cells

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T0930-06-42 - Differentiating the Effects of Different Oxidative Stress Conditions on Therapeutic Monoclonal Antibodies

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T1230-04-26 - Direct Powder Extrusion 3D Printing of Itraconazole-Hydroxypropylcellulose Formulations

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T1530-04-24 - Discovery and Characterization of Novel Solubilizing Excipients via High Throughput Methods

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M1030-06-37 - Dissolution Behavior of Neutral Drugs in FaSSIF Versions

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M1330-04-24 - Dissolution Mechanism of Amorphous Solid Dispersions as a Function of Drug Loading: Role of Polymer Hydrophobicity

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T1130-02-08 - Dissolution Methods for Evaluation of Oral Soluble Films: A Comparison Between USP-2 and a Novel “Basket-in-Tube” Method

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W0930-04-24 - Dissolution of Indomethacin Crystals into a Polymer Melt: Role of Diffusion and Fragmentation

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T0930-02-13 - Docetaxel Formulation in Polysorbate 80: A Complex and Sensitive System

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T1030-04-28 - Double-Layer Coated Solid Dispersion of Aprepitant (SYO-1906) for Enhancing Solubility and Bioavailability without Nanonization

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W1230-06-37 - Double-Layer Complex Tablets of Tadalafil and Amlodipime to Treat Erectile Dysfuncion and Hypertension

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W1230-01-06 - Downstream Process Considerations for Industrial Polymeric Submicron Particle Manufacturing

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M1430-07-49 - Drug Delivery from a Novel Fixed-dose ICS/LAMA/LABA MDI using Co-suspension Delivery Technology: Evidence of Consistency, Robustness, and Reliability

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M1330-01-03 - Drug Repositioning of Poorly Soluble Drug, Flubendazole via Metastable Salt Formation

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M1030-02-10 - Drug Supersaturation in Lipid-Based Drug Delivery Systems: Pharmacokinetic Studies with Celecoxib and Cinnarizine

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M1430-05-35 - Dry Powder Coating of a Novel Polymer for Taste Masking

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T1530-05-34 - Dry Powder Coating of Guaifenesin for Taste Masking in Orally Disintegrating Tablets

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T0930-01-02 - Dry Powder Formulation and Characterization of Potential Anti-Tuberculosis Drug CPZEN-45

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T1330-03-17 - Dry Powder Inhalation System for Non-Viral Gene Editing

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W0930-02-14 - Dual Functional Oleic Acid Magnetic Nanoparticles – In Vitro In Vivo Model for Glioblastoma Multiforme

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T1030-03-17 - Dual Neurovascular Targeting Platform for Stroke Based on Platelet-Like Nanoparticles Loaded with Ginkgolide B

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M1430-07-46 - ɑ_vβ₃-Targeted Liposomal Drug Delivery System with Attenuated Immunogenicity Enabled by Novel Peptides for Glioma Therapy

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T0930-05-32 - Edible Pyrazinamide-Loaded Orodispersible Hollow-Cup Carrier for Flexible Paediatric Dosing: Design and In Vitro Physicochemical Characterization

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W1130-05-33 - Effect of % HPO and Particle Size Levels of Hypromellose on the Release of Theophylline Controlled Release Tablets – A Quality by Design (QbD) Approach

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M1330-05-32 - Effect of Binder Level on Structure and Properties of Acetaminophen-Klucel Granules Prepared Using Continuous Twin-Screw Melt Granulation

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T1030-05-33 - Effect of Binder Type and Addition Method on Granule Properties in Continuous Twin Screw Wet Granulation

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T0930-07-45 - Effect of Encapsulated Gas in Microbubbles on Ultrasound-based Drug Delivery for Brain

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M1330-03-21 - Effect of Ethylene Oxide External Surface Sterilization on Stability of Ranibizumab in Prefilled Syringes

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M1130-05-34 - Effect of Excipients as Physical and/or Chemical Barriers on Abuse-Deterrent Extended Release Tablet

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M1230-07-49 - Effect of Formulation and Printing Parameters on Critical Quality Attributes of Printlets Printed by Selective Laser Sintering

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W1130-01-02 - Effect of Formulation Factors on Stability of Aqueous Solution Containing Pemetrexed

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M1030-01-05 - Effect of Formulation Variables on IOP Lowering Profiles of Delta⁹-Tetrahydrocannabinol Valine Hemisuccinate Loaded Nanoemulsion in Normotensive Rabbits

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T1130-03-19 - Effect of Incremental Changes in Surfactant of Semi-solid Topical Product and Its Effect on Performance Attribute

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T1230-05-35 - Effect of Magnesium Stearate Hydrate Form on Dissolution

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M1230-05-30 - Effect of Manufacturing Process Parameters on Mechanical Characteristics of Megabeads

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M1530-03-21 - Effect of Mixing Method as a Processing Parameter on the Adhesive Properties of Suspension-Based Transdermal Patches

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M1430-06-40 - Effect of Oxygen Level and Temperature on Stability of Lipids

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T1130-04-28 - Effect of Particle Morphology on the Mechanical Properties of Felodipine in PVP VA64 Spray-Dried Amorphous Solid Dispersions

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T1430-05-30 - Effect of PEG 400 and Polyvinyl Alcohol (PVA) on the pH-Sensitive Nanoparticles Formation and Stability

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T0930-06-36 - Effect of Permeation Enhancers on Insulin Solution via Sublingual Administration

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M1030-01-04 - Effect of pH on the Degradation Rate of Tacrolimus in Cyclodextrin Solution

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W1230-05-29 - Effect of pH-Modifiers on Solubility and Dissolution Rate of Telmisartan Solid Dispersions by Hot Melt Extrusion Technology

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M0930-05-30 - Effect of Polymer and Drug Loading on the Drug Release Profile and Solid-State Stability of Anti-Solvent Precipitated Lumefantrine Amorphous Solid Dispersions

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W1130-01-05 - Effect of Polymer Source Variation on In Vitro Drug Release of Leuprolide Acetate Microspheres

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M1430-02-13 - Effect of Preparation Temperature and Pore Former on PLGA Microparticles

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M1330-01-02 - Effect of Salt Form on AR-13503 Polymer System Compatibility and In Vitro Release Kinetics

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T1330-05-29 - Effect of Solvent on Re-crystallization of BCS Class II Drugs during Strip Film Manufacturing via Solution Casting

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T1130-01-04 - Effect of Stabilizer on Thermal Stability of Cediranib Maleate/Cyclodextrin Complexes in Aqueous Suspension

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T1030-05-32 - Effect of Sugar and PEG on Helix Stabilization of Alanine Based Peptides

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M1130-01-04 - Effect of Surfactant and Surface Coating Material on the Physicochemical Properties of Pimozide Nanoparticles

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T0930-03-20 - Effect of the Addition of Sodium Chloride and Sodium Citrate in Some Attributes of Soft Gelatin Capsules

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T1030-05-31 - Effects of Binder and Concentration of Polyethylene Oxide on the Mechanical Properties of Abuse Deterrent Formulations

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W1130-02-11 - Effects of Co-solvents on the Properties of Goserelin-Loaded PLGA Microsphere

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W1130-04-27 - Effects of Drying Temperature and Particle Size Control on Downstream Performance of Spray Dried Regorafenib/HPMCAS System Dissolved in Tetrahydrofuran (THF)

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W1030-02-13 - Effects of Fatty Acid Composition in Polysorbate on Biotechnology Drug Product Quality

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T1330-04-28 - Effects of Labrasol and Its Related Formulations on the Intestinal Absorption of Insulin and Elucidation of Their Absorption Enhancing Mechanisms

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W1030-07-43 - Effects of Microstructure on Lidocaine-Prilocaine Topical Product Performance

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T1130-05-33 - Effects of Processing and Formulation Variables on the Abuse-Deterrent Properties of PEO-Matrix Tablets

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M1430-07-47 - Effects of Sugar Blending on Mechanical Properties of the Dissolving Microneedles

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T1330-07-48 - Effects of Synthesis Parameters on Formation and Property of Thermo-Responsive Injectable Hydrogel Scaffolds for Stem Cell Engineering

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W0930-04-23 - Effects of Temperature and Ionic Strength of Dissolution Medium on Charge-Assisted Bond N⁺-H Mediated Gelation of Amorphous Lurasidone Hydrochloride

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W1130-01-04 - Efficacy of Ethanol Injection as a Low Temperature, Mechanical Shear Stress-free Method to Prepare Docetaxel-Folate-Targeted Liposomes

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M1130-02-14 - Efficient Cell Growth Inhibition Using Interferon-β pDNA Complexes of a Novel Phosphorylcholine-Based Polymer for Glioblastoma Therapy

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T0930-02-12 - Efficient Nanog Knockdown by Novel Ternary siRNA Complexes for Acute Myeloid Leukemia Therapy

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T1530-07-47 - Engineering 3d Printed Non-Viral Gene Delivery System for Bone Regeneration

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M1430-02-09 - Engineering of Piroxicam Loaded Polymer Hybrid Microspheres: Development, Characterization and In Vivo Evaluation

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T1330-04-25 - Enhanced Dissolution of Ibuprofen by Nonpareil Beads Containing Solubility Enhancers

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M1230-04-24 - Enhanced Oral Bioavailability of Paclitaxel by Self-Microemulsifying Drug Delivery System: Formulation Development, In Vitro and In Vivo Evaluation in Rabbits

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T1530-03-16 - Enhanced Subcellular Trafficking of Resveratrol Using Mitochondriotropic Liposomes in Cancer Cells

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T0930-07-47 - Enhanced Topical Delivery by a Microcurrent Generating Device

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T1130-03-17 - Enhanced Transdermal Delivery of 4-Phenylbutyric Acid– A Chemical Chaperon Effective Against Vesicant Warfare Chemicals

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M1230-04-26 - Enhancement of Aqueous solubility of Hispolon by Complexation with Sulfobutylether-β-Cyclodextrin

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W1230-03-17 - Enhancing the Delivery of Ibuprofen Through the Skin Using In Silico Modeling

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M1130-04-24 - Enhancing the Intestinal Permeability of Fenretinide Using Milk Derived Exosomes

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W1130-02-12 - Estimating Excipient Effect on Dissolution Profiles of Solid Solutions Using DDDPlus^TM

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M1130-07-49 - Eutectic Mixtures of Celecoxib with Adipic Acid/Saccharin: Improved Dissolution Rate and Wettability

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M0930-01-03 - Evaluating the Batch to Batch Reproducibility and Aerosol Performance of Spray Dried Albuterol Sulfate Formulations Using Cascade Impaction and Laser Diffraction Methods

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M1130-07-44 - Evaluating the Potential of Drug Eluting Contact Lenses for Treatment of Bacterial Keratitis Using an Ex Vivo Corneal Model

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M1130-05-32 - Evaluation of a New Grade of Highly-Compressible Methylcellullose for Direct Compression

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T1330-06-41 - Evaluation of an Automated, Acidic pH Protein Digestion for Reduced Levels of Artificial Deamidation in Biotherapeutic Peptide Mapping Studies

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M1530-07-48 - Evaluation of an Immediate-Release Formulation of Hydroxychloroquine Sulfate with an Interwoven Pediatric Taste-Masking System

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M1230-06-37 - Evaluation of Degradation Products of Insulin using High Resolution Mass Spectrometry with Proteome Discoverer and BioPharma Finder

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M1030-07-45 - Evaluation of Different Suppliers of Ethylene Vinyl Acetate Used in Intravaginal Rings

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T1530-04-28 - Evaluation of Distribution and Anticancer Activity of Conformational Switch-Based, pH-Sensitive Liposomes in 3D Multicellular Spheroids

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M1030-05-33 - Evaluation of Hot Melt Extruded Caffeine Pellets Containing POLYOX™ Water Soluble Resins

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T1430-06-39 - Evaluation of Influence of Pediatric Gastrointestinal Fluid Composition and Volume on Dissolution and Solubility of BCS II Drug

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W1130-05-32 - Evaluation of Instacoat CFC Formulation (Sugar Free) Using Chewing Gums

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W0930-05-32 - Evaluation of Instanute MB II, a Label Friendly High Solids Moisture Barrier Film Coating Formulation on Multivitamin Multimineral Tablets

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T0930-02-11 - Evaluation of Lansoprazole Enteric Hard Capsule Encapsulated by Sodium Alginic Acid

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W1130-02-10 - Evaluation of Metformin Tablet Using Wet granulation for Sustained Release

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T0930-03-19 - Evaluation of Metronidazole Bioavailability from Dermal Products Using an In Vitro Permeation Test (IVPT) Across Human Skin

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T0930-05-29 - Evaluation of Partially Pregelatinized Starch in a Continuous High Shear Wet Granulation Process

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T1330-03-20 - Evaluation of Quantitative Capsule Rupture Test Methods and Data Variability in Generic Omega-3 Capsule Applications

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T1430-05-35 - Evaluation of Taste Masking Efficiency of Kollicoat® Smartseal 100P Using Hot Melt Extrusion Techniques

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W1030-05-32 - Evaluation of Xanthan/ Locust bean blend Fluid Gels as Modified Release Oral Liquids

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T1430-03-17 - Ex Vivo Transport Study on Quercetin−Cyclodextrin Inclusion Complexes as Candidates for Nose−to−Brain Delivery

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M0930-02-08 - Excipient Similarity in Generic Formulations Containing Biopharmaceutics Classification System 3 Drugs

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M1130-02-10 - Exploitation of Coarse Black Phosphorus Using Plug-and-Play Technique for Inducing Chemo-Photo-Immunotherapy Against Colorectal Cancer

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M1530-04-22 - Exploratory Study of Aripiprazole-Adipic Acid Co-crystals by Hot Melt Extrusion Technique for Improved Solubility and Dissolution Rate

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M0930-06-40 - Exploratory In Vitro Mastication to Assess the Potential Accelerated Release of Fentanyl from a Transdermal Patch

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W0930-06-37 - Exploring Factors Affecting Nifedipine Biphasic Dissolution Profile Using an inForm Platform

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T1030-04-25 - Exploring Precipitation Inhibitors in Supersaturated Lipid-Based Formulations: Case Study Venetoclax

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T1230-05-31 - Exploring the Development of an Anhydrous Substitute for Petrolatum

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T1130-06-42 - Exploring the Physical Stability of Amorphous Drugs - The Thermodynamic Toolbox

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T0930-05-31 - Exploring the Role of Synbiotics as Carrier to Solidify Self Nano-emulsifying Drug Delivery System

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M1230-01-02 - Extending Shelf-Life of Therapeutic Proteins, Part 1: Arresting Rate of Aggregation during Agitation and Thermal Stress Using IgG as a Model Protein

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T1230-01-02 - Extending Shelf-Life of Therapeutic Proteins, Part 2: Reverting Reversible Aggregates into Monomers and Arresting Rate of Aggregation of Bevacizumab

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M1530-07-47 - Extractable Assessment of Blood Glucose Test Strips and Lancing Devices

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T1430-07-47 - Extremely Low Molar Ratio Captisol-Enabled Kidney Protective Iohexol Formulations – Comparative Cardiovascular Assessment in Anesthetized Male Dogs following Rapid Intracoronary Injection

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W1030-05-34 - Fabrication of Immediate Release Tablets via Fused Deposition Modeling 3D Printing Paired with Hot-Melt Extrusion

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W1130-07-49 - Fabrication of Shell-Core Delayed Release Tablet Using Dual Nozzle Fused Deposition Modeling 3D Printing Techniques

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T1530-01-07 - Factors of Bitterness in Clinical Medicines for Pediatric Patients Evaluated by Correlation between Physicochemical Properties or Biopharmaceutics Classification and Taste Sensor Responses

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T1030-06-39 - Factors to Consider During Filter Validation in Pharmaceutical QC

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M1130-04-25 - Fasted and Fed Bioequivalence Studies of SYO-1644 (Sorafenib Bioavailability Enhanced Tablets) in Beagle Dogs

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M1130-07-43 - FDA Draft Guidance, Use of Liquids and/or Soft Foods as Vehicles for Drug Administration – Why are Composition and Physicochemical Properties Important for Compatibility and Suitability Studies?

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T0930-03-18 - Film Forming Polymeric Solutions as Drug Delivery Systems for the Transdermal Delivery of Drugs

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T1230-05-30 - Fine Engineered Excipients for Improving the Disintegration and Dissolution Behaviors for BCS II Drugs

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W1130-07-46 - FITC Dextran Loaded PLGA Microneedles for Its Application in Transdermal Drug Delivery

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M1130-05-29 - Flow Behavior of the Cross-Linked Acrylic Acid Polymers Commonly Used in the Pharmaceutical Dosage Forms

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T1130-05-32 - Fluid Bed Coating of Microparticles: Effects of MicroCoat Technology on Drug Release

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T1230-04-28 - Rapid Transition of a Novel Celecoxib Formulation from a Fit-for-Phase Presentation to a Commercializable Product Using an Innovative Integrated Drug Development and Clinical Testing Platform

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T0930-06-38 - Residual Solvent Variations in Transdermal Drug Delivery Systems

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M1530-03-19 - Retinoid Containing Face Wash Lotion for the Treatment of Acne [DRL Publication No. 878]

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W1230-04-24 - Revaprazan-Loaded Surface-Modified Solid Dispersion: Physicochemical Characterization and In Vivo Evaluation in Rats

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M1130-03-21 - Review of Advanced Analytical Methods in Complex Polymeric Drug Substance Characterization

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M1530-06-37 - RP-HPLC Method Development, Validation, and Determination of Letrozole and Paclitaxel Combination in a Nanoliposome Formulation

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T1230-04-25 - Scaled-Up Production of Lumefantrine Nanoparticles

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W0930-04-28 - Simultaneous Improvement of Aqueous Solubility and Tabletability of Theophylline with Cocrystallization

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M0930-03-17 - Skin Follicular Targeting in Acne Treatment: Potentials with Isotretinoin-Loaded Delonix Nanoparticles

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M1530-03-16 - Skin Microporation and Iontophoresis for the Rapid Delivery of Ketamine for Treatment-Resistant Depression

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