Adult ID

Investigative ID

Oral Abstract

125 - Pathogenesis and Inflammatory Response

Presentations:

• 10:30 AM - 10:45 AM

  971 - The Role of Inflammation and Innate Effectors in Passive Immunization for Acinetobacter baumannii Infections
  Travis B. Nielsen, PhD – Loyola University Chicago; Jun Yan, MS – University of Southern California; Brian M. Luna, PhD – University of Southern California; Yuli Talyansky – University of Southern California; Robert A. Bonomo, MD – Louis Stokes Cleveland VA Medical Center; Brad Spellberg, MD – Los Angeles Coutny + University of Southern California
• 10:45 AM - 11:00 AM

  972 - A Mycobacterium Tuberculosis Secreted Lipid Triggers Cough Through a Neuronal Cough Receptor
  Paxton Cruz, B.S. – University of Texas Southwestern; Cody Ruhl, B.S. – University of Texas Southwestern; Michael Shiloh, MD, PhD – University of Texas Southwestern
• 11:00 AM - 11:15 AM

  973 - Single-Cell RNA Sequencing Analysis of Zika Virus Infection in Human Stem Cell-Derived Cerebral Organoids
  Karen Ocwieja, MD, PhD – Boston Children's Hospital; Alexandra Stanton – Harvard University; Alexsia Richards, PhD – Whitehead Institute; Jenna Antonucci, PhD – Inst. for Medical Engineering and Science, Massachusetts Inst. of Technology; Travis Hughes – Virology Graduate Program, Harvard Medical School; Alex Shalek, PhD – Massachusetts Institute of Technology; Rudolph Jaenisch, PhD – Whitehead Institute; Lee Gehrke, PhD – Massachusetts Institute of Technology
• 11:15 AM - 11:30 AM

  974 - PD-1 Immune Checkpoint Blockade Improves Survival and Promotes Fungal Clearance in an Immunosuppressed Murine Invasive Pulmonary Aspergillosis (IPA) Model
  Sebastian Wurster, MD – The University of Texas MD Anderson Cancer Center; Prema Robinson, PhD – The University of Texas MD Anderson Cancer Center; Nathaniel D. Albert – The University of Texas MD Anderson Cancer Center; Michail Lionakis, MD, ScD – National Institute of Allergy and Infectious Diseases; Dimitrios P. Kontoyiannis, MD – The University of Texas MD Anderson Cancer Center
• 11:30 AM - 11:45 AM

  975 - Roles of Type I and III Interferon in Severe Pathogenesis of Human Metapneumovirus
  John V. Williams, MD – University of Pittsburgh; Yu Zhang, PhD – University of Pittsburgh; Jiuyang Xu, BS – University of Pittsburgh; Margot Miranda-Katz, BS – University of Pittsburgh; Helen Rich, BS – University of Pittsburgh; Michelle Manni, PhD – University of Pittsburgh; Sharon Tollefson, BS – Vanderbilt University Medical Center; Saumendra Sarkar, PhD – University of Pittsburgh; John F. Alcorn, PhD – University of Pittsburgh

Co-Author(s)

• PC

  Paxton Cruz, B.S.

  Research Assistant
  University of Texas Southwestern
  Dallas, TX

  Disclosure: Nothing to disclose
• PR

  Prema Robinson, PhD

  Associate Professor
  The University of Texas MD Anderson Cancer Center
  Houston, TX

  Disclosure: Nothing to disclose
• CR

  Cody Ruhl, B.S.

  Graduate student
  University of Texas Southwestern
  Dallas, TX

  Disclosure: Nothing to disclose
• AS

  Alexandra Stanton

  Graduate Student
  Harvard University
  Cambridge, MA

  Disclosure: Nothing to disclose
• JY

  Jun Yan, MS

  Graduate Student
  University of Southern California
  Los Angeles, CA

  Disclosure: Nothing to disclose
• YZ

  Yu Zhang, PhD

  Postdoctoral fellow
  University of Pittsburgh
  Pittsburgh, PA

  Disclosure: Nothing to disclose
• NA

  Nathaniel D. Albert

  Research Coordinator
  The University of Texas MD Anderson Cancer Center
  Houston, TX

  Disclosure: Nothing to disclose
• BL

  Brian Luna, PhD

  Lecturer
  University of Southern California
  Los Angeles, CA

  Disclosure: ExBaq: Shareholder
• AR

  Alexsia Richards, PhD

  Postdoctoral Researcher
  Whitehead Institute
  Boston, MA

  Disclosure: Nothing to disclose
• JX

  Jiuyang Xu, BS

  Student
  University of Pittsburgh
  Pittsburgh, PA

  Disclosure: Nothing to disclose
• JA

  Jenna Antonucci, PhD

  Postdoctoral Researcher
  Inst. for Medical Engineering and Science, Massachusetts Inst. of Technology
  Cambridge, MA

  Disclosure: Nothing to disclose
• 

  Michail Lionakis, MD, ScD

  Chief, Fungal Pathogenesis Section, Laboratory of Clinical Immunology & Microbiology
  National Institute of Allergy and Infectious Diseases
  Bethesda, Maryland

  Disclosure: Nothing to disclose
• MM

  Margot Miranda-Katz, BS

  Research assistant
  University of Pittsburgh
  Pittsburgh, PA

  Disclosure: Nothing to disclose
• YT

  Yuli Talyansky

  Graduate Student
  University of Southern California
  Los Angeles, CA

  Disclosure: Nothing to disclose
• RB

  Robert Bonomo, MD

  Chief of Medicine
  Louis Stokes Cleveland VA Medical Center
  Cleveland, Ohio

  Disclosure: Nothing to disclose
• TH

  Travis Hughes

  Graduate Student/Medical Student
  Virology Graduate Program, Harvard Medical School
  Cambridge, MA

  Disclosure: Nothing to disclose
• DK

  Dimitrios Kontoyiannis, MD

  Professor, Infectious Diseases
  The University of Texas MD Anderson Cancer Center
  Houston, TX

  Disclosure: Amplyx: Advisor or Review Panel member
  Astellas Pharma: Grant/Research Support, Advisor or Review Panel member
  Cidara: Advisor or Review Panel member
  Mayne: Advisor or Review Panel member
  Merck & Co: Advisor or Review Panel member
  Pfizer: Advisor or Review Panel member
  Schering: Advisor or Review Panel member
• HR

  Helen Rich, BS

  Student
  University of Pittsburgh
  Pittsburgh, PA

  Disclosure: Nothing to disclose
• MM

  Michelle Manni, PhD

  Instructor
  University of Pittsburgh
  Pittsburgh, PA

  Disclosure: Nothing to disclose
• AS

  Alex Shalek, PhD

  Associate professor
  Massachusetts Institute of Technology
  Cambridge, MA

  Disclosure: Honeycomb Biotechnologies, Inc. : Consultant
• BS

  Brad Spellberg, MD

  Chief Medical Officer
  Los Angeles Coutny + University of Southern California
  Los Angeles, California

  Disclosure: Acuryx: Consultant
  Alexion: Consultant
  Bayer: Consultant
  BioAIM: Shareholder
  Cempra: Consultant
  ExBaq: Shareholder
  Forge: Consultant
  GlaxoSmithKline: Consultant
  Merck: Consultant
  Motif: Shareholder
  MycoMed: Shareholder
  NovaDigm Therapeutics: Shareholder
  Paratek: Consultant
  Peptilogics: Consultant
  Pfizer: Consultant
  Shionogi: Consultant
  Synthetic Biologics: Consultant, Shareholder
  Tetraphase: Consultant
• RJ

  Rudolph Jaenisch, PhD

  Professor
  Whitehead Institute
  Cambridge, MA

  Disclosure: Nothing to disclose
• ST

  Sharon Tollefson, BS

  Research assistant
  Vanderbilt University Medical Center
  Pittsburgh, PA

  Disclosure: Nothing to disclose
• LG

  Lee Gehrke, PhD

  Professor
  Massachusetts Institute of Technology
  Cambridge, MA

  Disclosure: E25 Biosciences: Other Financial or Material Support, Cofounder
• SS

  Saumendra Sarkar, PhD

  Professor
  University of Pittsburgh
  Pittsburgh, PA

  Disclosure: Nothing to disclose
• JA

  John Alcorn, PhD

  Associate Professor
  University of Pittsburgh
  Pittsburgh, PA

  Disclosure: Nothing to disclose

Moderator(s)

• 

  Jennifer Philips, MD, PHD

  Co-chief, Division of Infectious Diseases
  Washington University
  St. Louis, MO

  Disclosure: Nothing to disclose
• RB

  Robert Bonomo, MD

  Chief of Medicine
  Louis Stokes Cleveland VA Medical Center
  Cleveland, Ohio

  Disclosure: Nothing to disclose

Presenting Author(s)

• TN

  Travis Nielsen, PhD

  Medical Student
  Loyola University Chicago
  Forest Park, IL

  Disclosure: BioAIM: Shareholder
  ExBaq: Shareholder
• KO

  Karen Ocwieja, MD, PhD

  Clinical Fellow
  Boston Children's Hospital
  Somerville, MA

  Disclosure: Nothing to disclose
• JW

  John V. Williams, MD

  Professor
  University of Pittsburgh
  Pittsburgh, Pennsylvania

  Disclosure: GlaxoSmithKline: Advisor or Review Panel member
  Quidel: Advisor or Review Panel member
• SW

  Sebastian Wurster, MD

  Postdoctoral Fellow
  The University of Texas MD Anderson Cancer Center
  Houston, TX

  Disclosure: Nothing to disclose
• MS

  Michael Shiloh, MD, PhD

  Associate Professor
  University of Texas Southwestern
  Dallas, TX

  Disclosure: Nothing to disclose