Adult ID

HIV/TB/STD

Investigative ID

Global ID

Epi/Infection Control

Oral Abstract

308 - Fungi: Blood, Sweat, and Genes

Presentations:

• 3:15 PM - 3:30 PM

  2885 - A Host Transcriptional Signature for Accurate Diagnosis of Candidemia in the Hospital Setting
  Julie M. Steinbrink, MD – Duke University; Kaiyuan Hua, M.B. – Duke University; Rachel Myers, PhD – Duke University; Melissa D. Johnson, PharmD, MHS – Duke Center for Antimicrobial Stewardship and Infection Prevention; Jessica Seidelman, MD, MPH – Duke University; Ephraim L. Tsalik, MD, MHS, PhD – Duke University; Barbara D. Alexander, MD, MHS – Duke University; Micah T. McClain, MD, PhD – Duke University
• 3:30 PM - 3:45 PM

  2886 - Retrospective Case-Control Study of the Performance of the Karius Test, a Plasma Microbial Cell-Free DNA Next-Generation Sequencing Test, to Detect Invasive Mold Infections in Hematopoietic Cell Transplant Recipients with Pneumonia
  Joshua A. Hill, MD – Fred Hutchinson Cancer Research Center; University of Washington; David K. Hong, MD – Karius, Inc; Sudeb Dalai, MD – Karius, Inc; Carine Ho, MD – Karius, Inc; Desiree D. Hollemon, MSN, MPH – Karius, Inc; Lily Blair, PhD – Karius, Inc; Terry Stevens-Ayers, MSc – Fred Hutchinson Cancer Research Center; University of Washington; Michael Boeckh, MD PhD – Fred Hutchinson Cancer Research Center; Cynthia E. Fisher, MD, MPH – University of Washington
• 3:45 PM - 4:00 PM

  2887 - Identifying Candida albicans Transcription Factors (TFs) That Regulate Pathogenesis of Intra-Abdominal Candidiasis (IAC) by Screening a Deletion Mutant Library
  Cornelius J. Clancy, MD – University of Pittsburgh; Shaoji Cheng, MD, PhD – University of Pittsburgh; Kevin Squires, BA – University of Pittsburgh; Minh-Hong Nguyen, MD – University of Pittsburgh
• 4:00 PM - 4:15 PM

  2888 - STAT4 Mutation in Three Generations with Disseminated Coccidioidomycosis (DCM) Also Exhibits Increased Susceptibility to Coccidioidal Infection in Transfected Mice
  Daniel A. Powell, PhD – University College of Medicine; Lisa F. Shubitz, DVM – University of Arizona; Amy Hsu – National Institutes of Health; Joie Davis – National Institutes of Health; Steven M. Holland, MD – Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health; Joanne Berghout, PhD – University of Arizona; Yves A. Lussier, MD – University of Arizona; Jeffrey A. Frelinger, PhD – University of Arizona; John N. Galgiani, MD – University of Arizona
• 4:15 PM - 4:30 PM

  2889 - Skin Niche Conditions Trigger C. auris to Form Robust Biofilms That Resist Desiccation
  Jeniel E. Nett, MD, PhD – University of Wisconsin; Tarika Patel – University of Wisconsin; Chad Johnson – University of Wisconsin; John Kernien – University of Wisconsin

Co-Author(s)

• JH

  Joshua Hill, MD

  Assistant Memeber
  Fred Hutchinson Cancer Research Center; University of Washington
  Seattle, Washington

  Disclosure: Amplyx: Consultant
  Karius: Grant/Research Support
  Nohla therapeutics: Consultant
  Shire: Grant/Research Support
• DP

  Daniel Powell, PhD

  Research Scientist
  University College of Medicine
  Tucson, AZ

  Disclosure: Nothing to disclose
• SC

  Shaoji Cheng, MD, PhD

  Dr
  University of Pittsburgh
  Pittsburgh, PA

  Disclosure: Nothing to disclose
• DH

  David Hong, MD

  Vice President, Medical Affairs and Clinical Development
  Karius, Inc
  Mountain View, CA
• KH

  Kaiyuan Hua, M.B.

  Master of Biostatistics
  Duke University
  Durham, NC

  Disclosure: Nothing to disclose
• TP

  Tarika Patel

  Student
  University of Wisconsin
  Madison, WI

  Disclosure: Nothing to disclose
• LS

  Lisa Shubitz, DVM

  Research Scientist
  University of Arizona
  Tucson, AZ

  Disclosure: Nothing to disclose
• AH

  Amy Hsu

  Research Scientist
  National Institutes of Health
  Bethesda, MD

  Disclosure: Nothing to disclose
• CJ

  Chad Johnson

  Research Assistant
  University of Wisconsin
  Madison, WI

  Disclosure: Nothing to disclose
• RM

  Rachel Myers, PhD

  Research Scientist
  Duke University
  Durham, NC

  Disclosure: Nothing to disclose
• KS

  Kevin Squires, BA

  Mr
  University of Pittsburgh
  Pittsburgh, PA

  Disclosure: Nothing to disclose
• JD

  Joie Davis

  Ms
  National Institutes of Health
  Bethesda, MD

  Disclosure: Nothing to disclose
• CH

  Carine Ho, MD

  Clinical Research Associate
  Karius, Inc
  Redwood City, CA

  Disclosure: Nothing to disclose
• MJ

  Melissa Johnson, PharmD, MHS

  Associate Professor in Medicine
  Duke Center for Antimicrobial Stewardship and Infection Prevention
  Durham, NC

  Disclosure: Nothing to disclose
• JK

  John Kernien

  Graduate student
  University of Wisconsin
  Madison, WI

  Disclosure: Nothing to disclose
• MN

  Minh-Hong Nguyen, MD

  Professor of Medicine
  University of Pittsburgh
  Pittsburgh, PA

  Disclosure: Astellas: Consultant, Grant/Research Support
  Cidara: Consultant, Grant/Research Support
  Melinta: Grant/Research Support
  Merck: Consultant, Grant/Research Support
  Scynexis: Consultant
• SH

  Steven Holland, MD

  Dr.
  Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health
  Bethesda, Maryland

  Disclosure: Nothing to disclose
• DH

  Desiree Hollemon, MSN, MPH

  Head of Clinical Affairs
  Karius, Inc
  Redwood City, CA

  Disclosure: Karius, Inc. : Consultant
• JS

  Jessica Seidelman, MD, MPH

  Medical Instructor
  Duke University
  Durham, NC

  Disclosure: Nothing to disclose
• JB

  Joanne Berghout, PhD

  Dr.
  University of Arizona
  Tucson, AZ

  Disclosure: Nothing to disclose
• LB

  Lily Blair, PhD

  Bioinformaticist
  Karius, Inc
  Redwood City, CA

  Disclosure: Karius, Inc.: Employee
• 

  Ephraim Tsalik, MD, MHS, PhD

  Associate Professor
  Duke University
  Durham, NC

  Disclosure: BioFire: Grant/Research Support
  Biomerieux: Grant/Research Support
  CytoVale: Consultant
  Immunexpress: Consultant
  Predigen, Inc.: Officer or Board Member, Research Grant
  Qvella: Other Financial or Material Support, Research Collaboration
• BA

  Barbara Alexander, MD, MHS

  Professor of Medicine and Pathology
  Duke University
  Durham, NC

  Disclosure: Astellas Pharma: Advisory Board, Consultant, Grant/Research Support, Other Financial or Material Support, Research Grant
  Cidara: grant to institution, Research Grant
  F2G: grant to institution, Research Grant
  Lediant: grant to institution, Grant/Research Support, Other Financial or Material Support, Research Grant
  Scynexis: Consultant, grant to institution, Independent Contractor, Research Grant
• YL

  Yves Lussier, MD

  Dr.
  University of Arizona
  Tucson, AZ

  Disclosure: Nothing to disclose
• TS

  Terry Stevens-Ayers, MSc

  Research Technician
  Fred Hutchinson Cancer Research Center; University of Washington
  Seattle, Washington

  Disclosure: Nothing to disclose
• 

  Michael Boeckh, MD PhD

  Member
  Fred Hutchinson Cancer Research Center
  Seattle, Washington

  Disclosure: Ablynx: Consultant, Grant/Research Support
  Ansun Biopharma: Consultant, Grant/Research Support
  Astellas: Consultant, Grant/Research Support
  Bavarian Nordic: Consultant
  Chimerix: Consultant, Grant/Research Support
  Gilead: Consultant, Grant/Research Support
  GlaxoSmithKline: Consultant
  Helocyte: Consultant
  Janssen: Consultant, Grant/Research Support
  Lophius: Grant/Research Support
  Merck: Consultant, Grant/Research Support
  Moderna: Consultant
  Shire: Consultant, Grant/Research Support
  Vir Bio: Consultant, Grant/Research Support
• JF

  Jeffrey Frelinger, PhD

  Professor
  University of Arizona
  Tucson, Arizona

  Disclosure: Nothing to disclose
• MM

  Micah McClain, MD, PhD

  Associate Professor
  Duke University
  Durham, NC

  Disclosure: Nothing to disclose
• CF

  Cynthia Fisher, MD, MPH

  Assistant Professor
  University of Washington
  Seattle, Washington

  Disclosure: Karius, Inc.: Grant/Research Support

Moderator(s)

• 

  Jeniel Nett, MD, PhD

  Assistant Professor
  University of Wisconsin
  Madison, Wisconsin

  Disclosure: Nothing to disclose
• CC

  Cornelius Clancy, MD

  Associate Professor of Medicine
  University of Pittsburgh
  Pittsburgh, PA

Presenting Author(s)

• 

  Jeniel Nett, MD, PhD

  Assistant Professor
  University of Wisconsin
  Madison, Wisconsin

  Disclosure: Nothing to disclose
• JS

  Julie Steinbrink, MD

  Fellow
  Duke University
  Durham, NC

  Disclosure: Nothing to disclose
• SD

  Sudeb Dalai, MD

  Medical Director
  Karius, Inc
  Redwood City, CA

  Disclosure: Karius, Inc.: Employee
• JG

  John Galgiani, MD

  Director
  University of Arizona
  Tucson, AZ

  Disclosure: Nothing to disclose