Oral Papers: Medical Specialties II: Pulmonology, Infectious Disease
WEBB FELLOW: Comorbidity of Mental Illness and HIV/AIDS in Mozambique: Results from a Comprehensive Diagnostic Assessment in Primary Care Clinics of Maputo City
AUTHORS: Luis F. Pereira, Flavio Mandlate, Kate Lovero, Milton Wainberg.
HIV/AIDS was first described in 1981 and it rapidly took pandemic proportions. Thirty seven million people are currently living with HIV/AIDS worldwide, 70% of whom are from countries in sub-Saharan Africa (Kharsany & Karim, 2016). Mozambique is among the ten countries in the world with the highest infection rate, and has a nationwide prevalence of 13.2%. Within Mozambique, Maputo City has the third highest prevalence, at 16.9%.
HIV infection and mental illness have a bidirectional relationship. Several studies have identified HIV infection as a risk factor for the development of mental illness, in particular anxiety and depression. Moreover, mental illness is associated with vulnerability to risky behaviors and poor adherence to antiretroviral treatments, among others, which increase the risk of HIV infection (Nel & Kagee, 2011).
For this reason, screening for mental illness in both HIV-positive and HIV-negative persons is of utmost importance, as it may affect risk, prognosis, and outcomes. To our knowledge, this is the first study that assesses the prevalence of mental health disorders in HIV- positive and -negative patients in three different settings in Maputo City: two primary healthcare clinics and a tertiary hospital.
Cross-sectional study which included participants attending three medical facilities in Maputo City, Mozambique. Data was collected via direct interview, and also using several psychiatric diagnostic questionnaires (including WHODAS-36, PHQ-9, GAD-7, SSS-8, PC-PTSD, ASSIST, AUDIT, PSQ, and CSSRS) in the addition to the MINI plus (Mini International Neuropsychiatric Interview).
988 participants were interviewed, 63% of which were female. Three hundred and twelve (31.6%) had a diagnosis of HIV infection, and 33 (6.7%) reported being in treatment for a mental illness. Major depressive disorder was the most common psychiatric illness diagnosed via the MINI plus (319/33%), followed by psychosis (196/20.3%) and alcohol use disorder (124/12.8%). The remainder of the results are still pending.
Pending full analysis of the results
Kharsany, A. B., & Karim, Q. A. (2016). HIV Infection and AIDS in Sub-Saharan Africa: Current Status, Challenges and Opportunities. The open AIDS journal, 10, 34-48.
Nel A & Kagee A. (2011). Common mental health problems and antiretroviral therapy adherence. AIDS Care, Nov;23(11):1360-5.