State of the Academy
ACLP president Rebecca Weintraub Brendel, MD, JD, FACLP, opens the meeting with a welcome address that includes a State of the Academy presentation.
Educating for an Unknown Future: Training our Learners for...What?
Edward Hundert, MD
With rapid changes in medical education, the field of psychiatry, and the organizational structures of health care delivery, it is hard to know how to approach the training of the physician or psychiatrist of the future. This talk will explore current trends and attempt to identify some bedrock principles of teaching and learning which can guide program design to prepare learners headed into this unknown future.
What the C-L Psychiatrist Should Know About Genetics
Wade Berretini, MD, PhD
This presentation will review some common and rare clinical genetic scenarios which a C-L Psychiatrist may encounter. For commonly occurring psychiatric disorders, genetic testing for diagnostic purposes plays no role currently. This is so because commonly occurring psychiatric disorders are polygenic, meaning that hundreds to thousands of alleles convey risk, with each allele contributing a minute amount of risk. The concept of a polygenic risk score will be reviewed, including the substantial overlap of polygenic risk scores for distinct DSM-V diagnostic entities. Rarely, the C&L Psychiatrist may be consulted regarding an individual with a childhood onset severe psychotic disorder, perhaps complicated by developmental delay and substantial cognitive impairment. In this scenario, genetic testing for copy number variations (CNVs) is warranted. The presence of a CNV can be examined in family members to establish whether the CNV is inherited or de novo. The C&L Psychiatrist may also be asked to examine someone who has had substantial adverse effects for several medications in a particular class of psychiatric drugs, for example antidepressants. In this case, testing for cytochrome P450 alleles which convey poor metabolizer status may be indicated.