Presentation Authors: Hyung Ho Lee*, Gyeonggi-do, Korea, Republic of, Joon Chae Na, Dae Keun Kim, Young Eun Yoon, Woong Kyu Han, Seoul, Korea, Republic of
Introduction: We developed nomograms that predict chronic kidney disease III for the 6-months period after donor nephrectomy in living donors.
Methods: Data for living donor renal transplants were obtained from the Severance Hospital, Seoul, South Korea, from 2006 to 2018. Nomograms were designed using multivariate logistic regression models to predict 6 months estimated glomerular filtration rate below 60 mL/min/1.73 m2 based on pre-transplant information including demographic factors. Internal validation was performed using 1000 bootstrap resamples.
Results: Among 529 patients who underwent donor nephrectomy, 129 (24.38%) developed eGFR < 60 mL/min/1.73 m2 by 6 months after surgery. Age, gender, pre-operative estimated glomerular filtration rate, low-density lipoprotein cholesterol, uric acid, and smoking were independently associated with chronic kidney disease III, 6 months after surgery (Table 1). A nomogram including these 6 variables achieved 84.43% accuracy in predicting nomogram confined chronic kidney disease III by 6 months after surgery (Figure 1A, 1B).
Conclusions: We developed a simple and accurate prognostic tool for the prediction of living donor nephrectomy. This nomogram can be predicted chronic kidney disease III after living donor nephrectomy and high risk living kidney donors should be selected and need careful management after surgery to prevent chronic kidney disease III. These nomograms facilitate individualized patient care in living kidney donor