Presentation Authors: Giovanni Cacciamani*, Los Angeles, CA, Silvia Bassi, Marco Sebben, Anna Marcer, Verona, Italy, Luis Medina, Los Angeles, CA, Girogio Russo, Catania, Italy, Andrea Cocci, Firenze, Italy, Paolo Dell' Oglio, Milan, Italy, Nima Nassiri, Alessandro Tafuri, Andre Abreu, Los Angeles, CA, Alberto Briganti, Milan, Italy, Antonio Benito Porcaro, Verona, Italy, Francesco Montorsi, Milan, Italy, Inderbir Gill, Los Angeles, CA, Walter Artibani, Verona, Italy
Introduction: In the era of digital-data, the 'web' has become the primary source where individuals draw healthcare information. The aim of the present study is to determine worldwide public interest in prostate cancer (PCa) treatments, their penetrance and variation, and how they compare over time.
Methods: Worldwide search-engine trends analysis included electronic Google queries from people who searched PCa treatment options from January 2004 to August 2018, worldwide. Join-point regression (JPR) was performed. Comparison annual relative search volume (ARSV), average annual percentage change (AAPC) and temporal patterns were analysed to assess loss or gain of interest. Evaluations were made regarding (1) interest in PCa treatments; (2) comparison regarding people interest (3) the impact of the U.S. Preventive Service Task Force (USPSTF) Screening recommendation and National Comprehensive Cancer Network's (NCCN) guidelines endorsements on web searching for PCa treatments.
Results: The mean ARSV for 'prostatectomy' was 73% in 2004 and decreased reaching a nadir of 36% in 2014 (APC: -7.2%; 95%CI -7.8, -6.7; p < 0.01). Similarly, a decreased interest was recorded for 'radiation therapy' (AAPC:-3.2%, p=0.1), 'HIFU' (AAPC:-2.3%, p=0.1), 'hormonal therapy' (AAPC:-11.6%, p < 0.01), 'ablation therapy' (AAPC:-4.1%, p < 0.01), 'cryotherapy' (AAPC:-9.9%, p < 0.01), brachytherapy (AAPC:-8.3%, p < 0.01). A steep interest in 'active surveillance' (AS) was found (AAPC:+14.2%, p < 0.01) and 'focal therapy' (AAPC:+27.5%, p < 0.01). When trends where compared before and after NCCN and USPSTF recommendation, a consistent decrease of all the treatments option was found, while interest in Focal Therapy and AS showed an augmented mean ARSV (+19.6 and +31.6 respectively).
Conclusions: People are increasingly searching the web for PCa treatment options. A parallel decrease of interest was found for the non-monitoring treatments, except for Focal Therapy,while an important growth of appeal has been recorded for AS. Understanding people inquisitiveness together with their degree of knowledge could be supportive to guide counselling in the decision-making process and put effort in certifying patient information, avoiding them to fall in the pernicious trap of 'fake news'.