Presentation Authors: Daron Smith*, LONDON, United Kingdom, Stuart Irving, Norwich, United Kingdom, Sarah Fowler, John Withington, london, United Kingdom, Ben Turney, Oxford, United Kingdom, Oliver Wiseman, Cambridge, United Kingdom, Will Finch, Norwich, United Kingdom
Introduction: Details regarding infections treated before undergoing PCNL were added to the BAUS PCNL database in 2014. We analysed these data to assess the implications that pre-operative infection would have on the outcome of PCNL, especially for post-operative complications particularly regarding sepsis.
Methods: Data from the National UK PCNL database recorded between 2014-16 for patients with pre-operative treated infections were categorised into four groups:&[middot]patients who had received oral antibiotics,&[middot]patients admitted for iv antibiotics&[middot]patients who required emergency drainage (either by JJ stent or nephrostomy)&[middot]patients who required an ITU admission for sepsisChi squared analysis was performed between patients with and without prior infections
Results: 2630 patients were analysed. 1379 (52.4%) had no pre-PCNL infection (&[Prime]Controls&[Prime]). 1251 patients (47.6%) had prior treatment for infection, of whom 30.7% received at least one course of oral antibiotics, 6.9% required at least one admission for iv antibiotics, 8.3% required drainage before definitive surgery and 1.7% required an ITU admission for sepsis. Details regarding the relative likelihood of case abandonment, transfusion, Intra- and post-operative complications including fever and sepsis and Stone clearance results are shown in table 1.
Conclusions: Patients who require treatment of infection prior to PCNL have an INCREASED risk of post-op complications, especially of fever and sepsis, with the highest risk in patients who have had a previous ITU admission for Sepsis. Interestingly, post-operative stone clearance rates were DECREASED in patients with prior infection. These findings are useful for pre-operative counselling, postoperative vigilance and the interpretation of PCNL outcomes in the context of case complexity.