Presentation Authors: Atakelet A Ferede*, Gordon Smyth, Ponnusamy Mohan, Richard Power, James Forde, Dilly M Little, Dublin, Ireland
Introduction: Renal failure is common complication among recipients of prior nonrenal solid organ transplants, predominantly due to calcineurin inhibitor toxicity. As a result of extended life expectancy and better quality of life, these patients are increasingly being referred for consideration for kidney transplantation. In this study we examined our experience of recipients of kidney transplant post nonrenal solid organ transplantation and compare them to age-matched repeat kidney transplant recipients.
Methods: This is a retrospective review of a prospectively maintained database from the National Kidney Transplant Service (NKTS) of Republic of Ireland. The study period was from August 1993 to August 2017 and included adult living and deceased donor kidney transplant recipients. Patients who received kidney transplant after other solid organ transplantation were reviewed and were compared to patients who received repeat kidney transplant in the same period.
Results: There were a total of 433 patients in the study cohort (38 recipients of kidney transplant post other nonrenal solid organ transplant and 395 recipients of repeat kidney transplant). Baseline and transplant-specific characteristics of study population are outlined in Table 1. Death-censored 1-,5- and 10-year graft survival for the two groups were 94.7%/93.7%, 87.3%/86.4%, 78.6%/74%, respectively (P=509) (Figure 1).
Conclusions: Our national experience demonstrates that patients receiving kidney transplant after nonrenal solid organ transplant can expect allograft survival similar to patients receiving repeat kidney transplant.