Gastrointestinal Cancer

EDU 10 - (INTERACTIVE) Pancreas and Hepatobiliary Practice Updates

8:00 AM - 9:00 AM
Location: Room W194

Session Type: Education
1.00 AMA PRA Category 1 Credits™
1.00 CAMPEP Credits
1.00 MDCB Credits

Pancreatic and hepatobiliary cancers have poorer overall survival outcomes even when disease is localized to the primary site. However, paralleling our improved understanding of the biology of thee cancers, treatment paradigms have also continued to evolve with newer advances in surgical techniques, chemotherapeutic agents, RT techniques, and immunotherapy paradigms. Radiation dose, modality, fraction size, and sequencing are being evaluated actively. In this session, we will emphasize recent advances in RT for (i) pancreatic cancer focusing on imaging for borderline resectable disease, preoperative chemoradiation, radiation dose escalation, sparing of the spleen to reduce lymphopenia, and stereotactic body radiation therapy; and (ii) hepatobiliary cancer (hepatocellular and cholangiocarcinoma ) focusing on optimal imaging, radiation dose escalation, protons vs. photons, and stereotactic radiation therapy. The session will be organized in a case-based format with presentations by speakers spanning radiation oncology, medical oncology and radiology serving as moderators for each case that is discussed by all jointly and concluded by a summary slide with a take-home message. We plan to have about 12 minutes allocated to each case and 6 cases over roughly 75 minutes - the case mix will be 3 pancreatic, 2 hepatocellular carcinoma and one cholangiocarcinoma tentatively:
1. borderline resectable - imaging, preop chemoradiation
2. locally advanced - dose escalation? SBRT? spleen sparing? LAP07, Alliance
3. resected pancreas - adjuvant treatment
4. HCC - other liver directed therapies, dose escalation
5. HCC with PVTT - chemo, RT
6. intrahepatic cholangio - chemo, RT

Learning Objectives:


Sunil Krishnan, MD, FASTRO

MD Anderson Cancer Center

MD Anderson Cancer Center: Professor: Employee

Cancer Prevention and Research Institute of Texas: Research Grants;
Celgene: Research Grants;
DoD: Research Grants;
NIH: Research Grants

Taylor and Francis Group: Royalty

RTOG: Vice-chair, GI translational research program


Send Email for Sunil Krishnan


EDU 10 - (INTERACTIVE) Pancreas and Hepatobiliary Practice Updates

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