Central Nervous System

Panel 13 - Advances in the Management of Brain Metastases

1:00 PM - 2:15 PM
Location: Room W190

Session Type: Panel
1.25 AMA PRA Category 1 Credits™
1.25 CAMPEP Credits
1.5 MDCB Credits

Brain metastases are the most common brain malignancy, and they are most commonly treated with radiation therapy. Increasing survival from improving targeted agents for systemic disease in combination with increasing recognition of neurocognitive dysfunction after whole brain radiation has led to increased utilization of stereotactic radiotherapy and hippocampal avoidance whole brain therapy. This session seeks to review the latest literature and techniques for treating increasing numbers and sizes of brain metastases with stereotactic radiotherapy, combining newer systemic agents with radiation therapy, using whole brain radiation while avoiding the hippocampii, and managing special challenging cases such as recurrent or large brain metastases or cavities.

Learning Objectives:


Eric Mellon, MD, PhD

University of Miami

University of Miami: Assistant Professor of Radiation Oncology: Employee

ViewRay: Travel Expenses

Eric A. Mellon, MD, PhD is an Assistant Professor of the Departments of Radiation Oncology and Bioengineering at the University of Miami, Sylvester Comprehensive Cancer Center, Miller School of Medicine. He is a board certified radiation oncologist and graduate of the Physician Scientist Training Program of the University of Pennsylvania where he earned his PhD in MRI Physics.

Dr. Mellon has published over forty peer-reviewed articles on emerging MRI techniques for cancer and clinical radiation oncology--mostly in brain and pancreatic cancers. Clinically, he specializes in radiotherapy for tumors of the central nervous sytem and serves as co-leader of the neurologic cancer site disease group at the Sylvester Cancer Center. He is principal investigator and co-investigator on two NIH-funded trials for magnetic resonance spectroscopy guided radiotherapy of glioblastoma and assessment of response to therapy for brain metastases. His current basic research interests utilize MRI to probe the tumor microenvironment during therapy, giving information beyond just tumor size to evaluate early treatment response.


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Tony Wang, MD

Columbia University Medical Center

Columbia University Irving Medical Center: Associate Professor: Employee

Abbvie: Consultant: Travel Expenses; AstraZeneca: Advisory Board;
Cancer Panels: Honoraria;
Doximity: Consultant;
Elekta: Consultant: Honoraria: Travel Expenses;
Merck: Consultant;
Novocure: Advisory Board;
RTOG Foundation: Research Grants; Wolters Kluwer: Royalties

Doximity: Stock Options

Tony J. C. Wang, M.D., is the Co-Director of the Center for Radiosurgery and an Associate Professor of Radiation Oncology (in Neurological Surgery) at New York Presbyterian/Columbia University Irving Medical Center. He is recognized nationally for his extensive expertise in malignant and benign brain tumors. His research interests are in Gamma Knife stereotactic radiosurgery and brain tumors resulting in over 50 peer-reviewed publications. He has given over 50 invited lectures and visiting professorships nationally and internationally.

He serves on several national and international working groups developing guidelines for brain tumor management and stereotactic radiosurgery. He is an editor for 2 radiation oncology textbooks and a writer for over 15 book chapters. He serves as an Associate Editor on the Radiation Oncology Section of Neurosurgery, the official journal of the Congress of Neurological Surgeons, and as a reviewer for International Journal of Radiation Oncology, Biology, and Physics, Practical Radiation Oncology, and Journal of Neuro-Oncology as well as many others.

Dr. Wang received his B.A. and M.D. degrees from University of Missouri Kansas City Medical School, during which time he was also a Clinical Research Training Program Fellow at the National Institutes of Health, Bethesda, Maryland. He received internship training at Flushing Hospital Medical Center. Dr. Wang received his radiation oncology training at New York Presbyterian Hospital (Columbia campus), where he was Chief Resident from 2011-2012.

As a member of the Brain Tumor Center and Pituitary Tumor Center at Columbia, Dr. Wang is part of a multidisciplinary team that brings expertise from multiple specialties, including neurosurgery, neuro-oncology, neuroradiology, and neuro-endocrinology.


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Panel 13 - Advances in the Management of Brain Metastases

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