Assistant Professor - Department of Mechanical Engineering & School of Biomedical EngineeringAssociate Director - Orthopaedic Bioengineering Research Laboratory
Colorado State University
Fort Collins, Colorado
Dr. McGilvray’s research has been focused on the implementation of an implantable biocompatible micro-electric-mechanical system (bioMEMS) sensor that allows for the telemetric in vivo prediction of whether bone fractures in a large animal model will go on to a full union before it can be detected radiographically. This work has been supported by a competitive grant from the National Institutes of Health. Specifically, using a flexible bioMEMS technology platform, he has proposed to utilize a multi-sensor configuration on a single implant to measure the temporal and spatial implant strain profiles during bony healing, providing a measure of the unique in vivo variations with respect to the transient mechanical environment (i.e. implant strain profile) that are associated with specific implant designs and fracture type/severity combinations. The objective of the proposed work is to utilize multiple flexible sensor–implant constructs to predict the ultimate outcome of the healing process during the acute time period when applied to clinically challenging tibial and femoral fractures.
Additionally, he has recently designed a novel technique for printing the bioMEMs circuitry directly on bone (boneMEMs) and have leveraged existing technology to produce a new class of sensors which we postulate can be used to directly monitor bone graft loading and incorporation in vivo. This work has been supported by a competitive grant from the National Institutes of Health (PI: McGilvray, 1R21AR072371-01, 07/2017 to 06/2019, $275k direct costs). It is Dr. McGilvray’s overreaching goal to develop an enabling technology that will allow clinicians to determine if bone allografts will be able to properly heal following implantation. This is of great clinical value since massive bone allografts are used for reconstruction after large segmental bone loss due to trauma or tumor resections, but monitoring the degree of their incorporation with host bone using currently available diagnostic techniques is intractable.
Friday, October 18
1:30 PM – 2:30 PM