Clinical Oncology: Outcomes & Complications
Moderated Poster Session
MP23-4 - Recurrence Patterns of Renal Cell Carcinoma after Robotic Partial Nephrectomy
Saturday, September 22
2:00 PM - 4:00 PM
Location: Room 253
Introduction & Objective : Robotic partial nephrectomy (RPN) has an established role in the treatment of renal cell carcinoma (RCC) with an oncologic outcome that is comparable to open surgery. Indeed, the technique and the outcome of RPN was replicated by multiple authors and from different centers. Here, we describe the recurrence patterns of RCC in patient underwent RPN at our institute.
We reviewed prospectively collected data of the patient who underwent RPN with final diagnosis of RCC, between September 2009 and March 2018. RPN was utilized routinely in the treatment of small renal masses (≤ 4 cm) and selectively in the treatment in larger mass (4-7 cm) at our institute. All patients had negative margin except 2 .
Out of the 335 patients underwent RPN at our institute, 269 patients (80.2%) were diagnosed with RCC. During the mean follow up period of 39 months (ranging 1 -96) we identified 9 cases of recurrence. The average lag time from the RPN and recurrence was 31 months (18 -72). The pattern of recurrence presented as the following: 2 patients had trocar site recurrence, 2 patients developed locoregional recurrence with infiltration of the RCC in the perinephric fat and lymph nodes. 3 patient had recurrence of the disease in the tumor bed. Two patients developed second primary tumor in the other kidney. No patient presented with distal metastasis after RPN.
RCC has excellant (96.6%) 8 years cancer free survival when amenable to be treated with RPN. Tumors with histologic grade ≥3, larger tumors ≥ 4 cm, and tumors with local invasion T3 tumors are more likely to recur. Papillary pathology was found to be surrogate with recurrence. Positive margin did not translate into recurrence in our series, though the small number of positive margine (0.7 %).