Basic Science: BPH/LUTS

Moderated Poster Session

MP3-7 - The role of the photovaporization of the prostate (PVP) with GreenLight 180W XPS in patients with large prostates: Is it time to change the standard of treatment?

Thursday, September 20
4:00 PM - 6:00 PM
Location: Room 243

Introduction & Objective :

According to several guidelines, PVP is as effective as TURP in prostates 80mL.However, with the availability of the Moxy fiber and the 180W power, some authors have stated this technique may have a role in the management of larger prostates. We aim to determine effectiveness and safety of PVP in patients with prostates >80mL.


Methods :

An observational retrospective study was conducted in patients who underwent PVP between 2012 and 2017. Prostate volume was divided into 2 categories: ≤80mL and >80mL. Intra and postoperative complications, symptomatic improvement (VAS), IPSS and quality of life (QoL) were recorded. Descriptive and inferential statistics were employed.


Results :

We included 533 patients, 65.8% with prostates ≤80 mL and 34.2% >80 mL. Table 1 shows preoperative characteristics. Median follow-up was 21 months (IQR 8-38). IPSS and QoL improved from 17 to 5 and 4 to 1, respectively, in patients with prostates >80 mL. Compared to smaller prostates, no significant differences were found. The complication rates according to the Clavien-Dindo classification in prostates >80mL were 24% (I-II) and 9.9% (III-IV), which are slightly greater compared to smaller prostates (Table 2). A multivariate logistic regression analysis showed that prostate volume was associated with moderate-to-severe bleeding (OR 3.4, 95% CI 1.2-9.5), the need for bleeding control (OR 2.2, 95% CI 1.0-4.7), conversion (OR 19.1, 95% CI 2.3-157) and blood transfusion (BT) (OR 28.4 95% CI 2-404).


Conclusions : PVP with GreenLight 180W XPS is safe and effective in patients with prostates >80 mL. As expected, bleeding, conversion and the need for BT was greater in larger prostates, but these rates are notably lower compared to TURP (BT>5%) and open prostatectomy (BT 8-19%). Given the increasing evidence supporting the use of PVP in large prostates, we believe it could become a standard of care in the near future.

Carlos Gustavo Trujillo

Urologist
Hospital Universitario Fundación Santa Fe de Bogotá and Universidad de los Andes School of Medicine

My name is Carlos Gustavo Trujillo. I work as a urologist in the Foundación Santa Fe de Bogotá the university hospital of Los Andes University where I also work as a professor at the medical school. I'm part of the research team of the urology department and I'm currently working for the creation of the clinical care center for non-metastatic prostate cancer in our institution.

Presentation(s):

    Send Email for Carlos Trujillo

    Alejandra Bravo-Balado

    Research Assistant
    Hospital Universitario Fundación Santa Fe de Bogotá and Universidad de los Andes School of Medicine

    Presentation(s):

      Send Email for Alejandra Bravo-Balado

      Juan Ignacio Caicedo

      Urologist
      Hospital Universitario Fundación Santa Fe de Bogotá and Universidad de los Andes School of Medicine

      Presentation(s):

        Send Email for Juan Ignacio Caicedo

        Tatiana Higuera

        Medical student
        Hospital Universitario Fundación Santa Fe de Bogotá and Universidad de los Andes School of Medicine

        Presentation(s):

          Send Email for Tatiana Higuera

          Laura Zuluaga

          Research Assistant
          Hospital Universitario Fundación Santa Fe de Bogotá and Universidad de los Andes School of Medicine

          Presentation(s):

            Send Email for Laura Zuluaga

            Mauricio Plata

            Chairman Department of Urology
            Hospital Universitario Fundación Santa Fe de Bogotá and Universidad de los Andes School of Medicine

            Presentation(s):

              Send Email for Mauricio Plata


              Assets

              MP3-7 - The role of the photovaporization of the prostate (PVP) with GreenLight 180W XPS in patients with large prostates: Is it time to change the standard of treatment?



              Attendees who have favorited this

              Please enter your access key

              The asset you are trying to access is locked. Please enter your access key to unlock.

              Send Email for MP3-7 - The role of the photovaporization of the prostate (PVP) with GreenLight 180W XPS in patients with large prostates: Is it time to change the standard of treatment?