BPH/LUTS: Electrosurgery, Lasers & Other Technology
Moderated Poster Session
MP3-16 - Causative urodynamic factor for BPH related chronic obstructive uropathy: Preliminary study
Thursday, September 20
4:00 PM - 6:00 PM
Location: Room 243
Introduction & Objective :
BPH has been suggested as a cause of chronic kidney disease. However, it has never been reported that which urodynamic parameter exerts an influence on kidney damage. We investigated which BPH related urodynamic parameter(s) is(are) related to upper tract obstruction.
Among Patients with prostate size over 40g, eGFR40) were enrolled in the present study. Mercaptoacetyltriglycine (Tc-99m MAG3) scan was performed in all enrolled pathients. Schaffer grade was also considered. Compliance below 35 was considered as poor compliance, and Tmax 1/2 in MAG3 was considered as potential obstruction.
Totally 20 patients were evaluated. Mean values of age (yrs), prostate size (g), bladder compliance, Schaffer grade, and BOOI were 72.3±6.8, 76.3±29.8, 40.2±19.3, 3.6±1.4 and 85.0±45.3, respectively. Mean Tmax 1/2 (min) were 12.3±7.3 in left side and 13.5±9.7 in right side. At least one side upper tract obstruction was observed in 11 patients. Among 20 enrolled patients, only 6 patients were re-evaluated to check the change of MAG3 parameters 6 months later.
Statistical analysis showed that poor compliance was related to upper tract obstruction (at least 1 side) (p=0.005, OR=2.75), however BOOI or Schaffer grade was not associated with upper tract obstruction (p=0.172, p=0.280, respectively).
MAG3 data (paired t-test, p=0.075 in left, p=0.028 in right) in 6 patients showed that improvement the urinary drainage into the urinary bladder (Figure).
Bladder obstruction index or Schaffer grade is not related to upper tract damage. Only poor compliance is a reliable urodynamic factor for upper tract damage in BPH patients, which can be improved surgically.