Basic Science: BPH/LUTS

Moderated Poster Session

MP3-1 - Tissue effects of different laser fibre diameters using 1.94 µm Tm:fibre lasers in a pig kidney model

Thursday, September 20
4:00 PM - 6:00 PM
Location: Room 243

Introduction & Objective : Aim of this study was to evaluate the ablation capacity and coagulation depth of different laser fibre diameters using a high peak power pulsed Thulium (Tm):fibre laser and a continuous wave (cw) Tm:fibre laser in a pig kidney model.


Methods : All soft tissue samples were obtained from a pig kidney and mounted on a motorized translation XY stage to ensure a precise speed of cutting (2 mm/s). A cw Tm:fibre laser (120-W peak power) and a prototype high peak power pulsed Tm:fibre laser (1000-W peak power) both emitting at 1.94 µm were used at the same average power of 60-W and 120-W, respectively. Energy was delivered using a 200 µm and a 600 µm bare-ended fibre. After Lactat Dehydrogenase (LDH)-staining of the embedded specimens, histological evaluation was performed to compare vaporization volume, ablation depth, thermo-mechanical damage zone, coagulation zone and the depth of necrotic tissue layer between both Tm:fibre lasers and fibre diameters, respectively.


Results : Using the cw Tm:fibre laser at 120-W (cutting speed 2 mm/s), no significant differences were seen between both fibre diameters with regard to vaporization volume (24.6 vs. 28.2 mm3/s), ablation depth (5.7 vs. 5.6 mm), thermo-mechanical damage zone (0 vs. 0 mm2) and the coagulation zone (18.1 vs. 11.3 mm2). Regarding the high peak power pulsed Tm:fibre laser, no differences were found between both fibre diameters with regard to vaporization volume (4 vs. 3 mm3/s), ablation depth (2.7 vs. 2.5 mm), thermo-mechanical damage zone (1 vs. 1.3 mm2) and the coagulation zone (3.1 vs. 2.2 mm2) at 120-W, respectively. Regarding the laser fibre diameters, there were also no differences between the histologically measured parameters at 60-W in both Tm:fibre lasers. However, comparing the power of both lasers, the vaporization volume of the cw Tm:fibre laser at 60-W was significantly lower compared to 120-W using 200 and 600 µm fibres, respectively, whereas the high peak power pulsed Tm:fibre laser did not show significant differences at 60-W compared to 120-W with regards to the vaporization volume. 


Conclusions : The laser fibre (200 or 600 µm) diameter did not affect vaporization volume, ablation depth, the thermo-mechanical damage zone and the coagulation zone in cw or high peak power pulsed Tm:fibre lasers. However, the cw Tm:fibre laser produces a coagulation zone five times larger than the high peak power pulsed Tm:fibre laser regardless of the fibre core diameter.

Benedikt Becker

Resident
Asklepios Klinik Barmbek, Department of Urology

Dr. Becker is a resident of urology in the urological department of the Asklepios Hospital Barmbek in Hamburg, Germany. He studied in Giessen and Lübeck (both Germany). His main scientific interest is the broad spectrum of endourology, especially laser treatment of benign prostatic obstruction. He is an active member of the German Society of Urology (DGU), the German Society of Residents in Urology (GeSRU), and the Endourological Society (WCE). At this time, he is participating in the Two Year fellowship program in Endourology/Stone Surgery.

Presentation(s):

    Send Email for Benedikt Becker

    Christopher Netsch

    Consultant
    Asklepios Klinik Barmbek, Abteilung für Urologie

    Dr. med. Dr. habil. Christopher Netsch, MD, FEBU is an Assistant Professor of Urology at the Semmelweis University of Budapest/Hungary. He received his medical degree from the University of Mainz/Germany. His training in urology was conducted at the Inselspital Bern/Switzerland, Städtisches Klinikum Karlsruhe/Germany and at the Asklepios Klinik Barmbek/Germany. After his board certification in 2011 (Hamburg/Germany), Dr. Netsch became a consultant urologist at the Asklepios Klinik Barmbek/Germany. Dr. Netsch completed his Endourology Fellowship at the Asklepios Klinik Barmbek in 2012. He was also qualified as a Fellow of the European Board of Urology (FEBU) in 2015.
    Dr. Netsch`s research focuses on urolithiasis and minimally-invasive therapies for BPH. He has authored or co-authored over 70 peer-reviewed journal articles and numerous book chapters. He was awarded with the Mauermayer award of the German Society of Urology (DGU) in 2013 and the Hans Marberger award of the European Association of Urology (EAU) in 2014. He is currently an editorial consultant for the World Journal of Urology.
    Dr. Netsch is a member of the DGU Urolithiasis Guidelines committee. He is also an active member of numerous national and international societies such as the DGU, EAU, and the Endourological Society. He is also a member of the DGU working group in Endourology and the EAU section of Uro-Technology (ESUT): Lower Tract Section.

    Presentation(s):

      Send Email for Christopher Netsch

      Dmitry Enikeev

      Deputy Director for Science
      Institute for Urology and Reproductive health, Sechenov University

      Deputy Director for Science, Institute for Urology and Reproductive health, Sechenov University

      Presentation(s):

        Send Email for Dmitry Enikeev

        Petr Glybochko

        Director
        RI for Uronephrology, Sechenov University

        Presentation(s):

          Send Email for Petr Glybochko

          Leonid Rapoport

          Deputy Director
          RI for Uronephrology, Sechenov University

          Presentation(s):

            Send Email for Leonid Rapoport

            Mark Taratkin

            Researcher
            Institute for Urology, Sechenov University

            Researcher at the Institute for Urology and Reproductive health, Sechenov University.
            Head of the laser technology lab.

            Presentation(s):

              Send Email for Mark Taratkin

              Andreas J. Gross

              Head of Department
              Asklepios Klinik Barmbek, Abteilung für Urologie

              Presentation(s):

                Send Email for Andreas J. Gross


                Assets

                MP3-1 - Tissue effects of different laser fibre diameters using 1.94 µm Tm:fibre lasers in a pig kidney model



                Attendees who have favorited this

                Please enter your access key

                The asset you are trying to access is locked. Please enter your access key to unlock.

                Send Email for MP3-1 - Tissue effects of different laser fibre diameters using 1.94 µm Tm:fibre lasers in a pig kidney model