Category: Endoscopic

MP30-12 - Narrow Band Imaging trans-urethral resection of the bladder in patients with pT1 high grade disease: an effective treatment with a low persistence rate on second trans-urethral resection of the bladder

Sun, Sep 23
2:00 PM - 4:00 PM

Introduction & Objective :

To evaluate the persistent rate on repeated transurethral resection of the bladder (re-TURB) 6 weeks after the first TURB in patients with pT1HG disease undergoing resection of the margins and bed on Narrow Band Imaging.

Methods :

A consecutive series of patients undergoing TURB and a diagnosis of pT1 high grade disease were prospectively enrolled. On initial TURB patients underwent classic white light resection of the tumour followed by narrow band image (NBI) resection of margins and bed. After 6 weeks from the initial TURB, patients underwent a re-TURB under white light. Persistence rates on re-TURB were recorded.

Results :

Overall 797 patients underwent TURB, out of them 126 patients with pT1 high grade disease were included in the study. The total number of lesions was 226 meaning 1.79 lesions per patient.   On re-TURB 21/126 (17%) of the patients presented residual disease with a total of 28/226 (12%) lesions identified. All these patients presented a pTa residual disease. Out of them 8/21 (38%) presented bladder cancer on the resection bed and 13/21 (62%) presented bladder cancer on margins.

Conclusions :

Narrow Band Imaging trans-urethral resection of the bladder is an oncological effective procedure in the treatment of pT1HG disease. The procedure has a 17% of persistence rate which is inferior when compared to the available evidence on white light TURB. Further multicenter studies are needed in order to validate our results.

barbara cristina Gentile

villa claudia
Rome, Lazio, Italy

Roberto Giulianelli

Rome, Lazio, Italy

Luca Albanesi

Rome, Lazio, Italy

Gabriella Mirabile

Rome, Lazio, Italy

Riccardo Lombardo

Rome, Lazio, Italy

Paola Tariciotti

Rome, Lazio, Italy

Giorgio Rizzo

rome, Lazio, Italy

Pietro Aloisi

Rome, Lazio, Italy