Category: Clinical Stones: PCNL
Introduction & Objective :
Definitions of high throughput stone units differ in the UK and internationally and despite
international and national pooled PCNL outcome data being available for some years, there
are still very few series reporting over 500 cases.
A combination of retrospective and prospective data were collated from 2000-2016 and
compared against large single centre international series And pooled multicentre data.
Data were available on 801 unique cases performed between 2000 and 2016, mean age
55.2 (S.D. = 14.8) (range 17-93).
The mean change in haemoglobin was found to be 1.65 g/dL +/- 0.05, n= 630. 27 patients
required transfusion post –operatively (3.7%).
In 470 cases, the information on pre-op UTI was available. 119 (25%) demonstrated
evidence of bacteriuria pre-operatively. The most common isolated species were E. Coli and
Proteus. Those infected did demonstrate, on average, a higher drop in Hb during surgery;
however, this difference was not found to be statistically significant.
Where the information was available, creatinine rise during surgery was calculated. The
mean rise was found to be 15.21 umol/L (S.E.: 2.08, n = 208). The mean drop in eGFR was
estimated to be 7.35 ml/min/1.73m2 (+/- 0.895, n=205).
In total, 8 cases of 801 (1%) required admission to higher level care. There was 1 small
bowel puncture and 1 pleural perforations causing haemo pneumothorax.
Sub-selective embolization occurred in 1 case 0.12 % and there were no peri-operative deaths
in this series.
Published data comparing single centres with >500 cases as multicentre pooled data will be presented.
In the age of transparent informed consent, single centre rather than pooled outcome data
should be utilised
Andreas Auer– Urology Registrar (ST6), Queen Alexandra Hospital Portsmouth, Southampton, England, United Kingdom
Michal Barabas– Medical Student, University of Cambridge, Cambridge, England, United Kingdom
Richard Cetti– Consultant, Launceston, Tasmania, Australia
Ann Rogers– Queen Alexandra Hospital Portsmouth, Prtsmouth, England, United Kingdom
Byron Walmsley– Queen Alexandra Hospital, Portsmouth, England, United Kingdom
Stephen Keoghane– Consultant, Bury St Edmunds, England, United Kingdom
Urology Registrar (ST6)
Queen Alexandra Hospital Portsmouth
Southampton, England, United Kingdom
University of Cambridge
Cambridge, England, United Kingdom