Exhibitor Tutorial

Develop and Validate GPCR Assays for Screening

Monday, February 5
2:00 PM - 2:45 PM
Location: Room 5A

Multispan is well known for our production of quality stable GPCR cell lines along with their corresponding functional assays. Through these activities, we have observed many things that have influenced these activities. In this tutorial, we will share some of these secrets to help you build better cell lines. In addition, we will share experiences in developing cell lines and how the selection of a parental cell line is critical to success and how receptor expression levels are critical to the signaling profiles that are seen. It is also critical to be able to measure activity in a cell that is downstream to the initial signal. To that end, we have expanded our in-cell ELISA assays and have increased our ability to measure activity from native cells. We hope that by attending this tutorial, you will learn methods that will help you to perform assays better and will also learn about Multispan and how we may be able to help you in your drug discovery efforts.

Jennifer Pham

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Lisa Minor

Business Development Consultant
Multispan, Inc.

Dr. Minor is a well recognized scientific expert with 25 years of experience in drug discovery encompassing several therapeutic areas, high throughput screening and safety profiling through her tenure at Johnson and Johnson Pharmaceuticals. She is an editor for the Assay Guidance Manual for NIH, served for 8 years as a member of the advisory board for the Society for Biomolecular Sciences (now Society for Laboratory Automation and Screening) and on the Scientific Advisory Board for the National Toxicology Program and chaired multiple international assay development meetings. She has been consulting for Multispan since January, 2012. Dr. Minor received her postdoctoral training at the Medical College of Pennsylvania and obtained her Ph.D. in Biological Chemistry from the Pennsylvania State University.

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Develop and Validate GPCR Assays for Screening

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