Special Interest Group (SIG)

Compound Combination Special Interest Group (SIG)

Wednesday, February 7
8:00 AM - 9:15 AM
Location: 14B

The mission of the SLAS Compound Combination Screening SIG is to create a knowledge-sharing forum for screening practitioners active in the field of compound combinations. As such, the goal is to mature the field of compound combination screening, aimed at better science that accelerates the pace of drug discovery.

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Oliver Leven

Head of Screener Business, Europe
Genedata AG, Switzerland

Studied Chemistry at University of Cologne, Diplom-Chemiker, Dr. rer. nat. in Biochemistry and Bioinformatics (University of Cologne, 1999), Founder of Science Factory (2000), Since 2003 with Genedata, enabling screening workflows for customers, e.g. supporting High Content, Combination and high-throughput screening. Running the Genedata Ready to Run initiative, partnering with instrument vendors and other software vendors. Heading the Screener Business in Europe since 2017.

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Rajarshi Guha

Research Scientist
NIH

Rajarshi Guha is Group Leader (Research Informatics) in the Division of Pre-Clinical Innovation at NCATS. With over 10 years of experience in handling, analysing and visualizing chemical information, he brings a diverse range of skills and experience to his current role at NCATS. He is involved in small molecule development projects in a variety of therapeutic areas including rare cancers and infectious diseases. He is also involved in software and algorithm development in the areas of cheminformatics methods and large scale infrastructure projects including Pharos (http://pharos.nih.gov/) BARD (http://bard.nih.gov/). His research interests focus on methodology development to analyze and visualize chemical biology data sets, with specific focus on techniques to link chemical structure information to molecular, bibliographic, genomic and clinical covariates. He has held multiple leadership roles in the American Chemical Society’s Division of Chemical Information and is currently a co-Editor in Chief of the Journal of Cheminformatics.

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Rajarshi Guha

Research Scientist
NCATS

Rajarshi Guha is an informatics research scientist in the Division of Pre-Clinical Innovation at NCATS. With over 10 years of experience in handling, analysing and visualizing chemical information, he brings a diverse range of skills and experience to his current role at NCATS. He is involved in small molecule development projects in a variety of therapeutic areas including rare cancers and infectious diseases. He is also involved in software and algorithm development in the areas of cheminformatics methods and large scale infrastructure projects including Pharos (http://pharos.nih.gov/) BARD (http://bard.nih.gov/) and the Trans-NIH RNAi Screening Initiative. His research interests focus on methodology development to analyze and visualize chemical biology data sets, with specific focus on techniques to link chemical structure information to molecular, bibliographic, genomic and clinical covariates to explain the effects of small molecules in the context of larger biological systems. His recent work has focused on the development of novel analytic and visualization methods for combination screening results. An active member of the cheminformatics community, he has made contributions to various open-source projects and has held multiple leadership roles in the American Chemical Society’s Division of Chemical Information and is currently a co-Editor in Chief of the Journal of Cheminformatics.

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Daniel Urban

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